Nā Glucovans: nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana

1 papa pāahī-kiʻi e pili ana:

Kāleka 2.5 mg + 500 mg:

Nā ʻāpana hoʻoikaika: glibenclamide - 2,5 mg, metformin hydrochloride - 500 mg.

Kuhi: ka sodium croscarmellose - 14.0 mg, povidone K 30 - 20,0 mg, cellulose

microcrystalline - 56.5 mg, magnesium stearate - 7.0 mg.

Shell: opadry OY-L-24808 ulaula - 12.0 mg: monoholate lactose - 36,0%,

15prP hypromellose - 28.0%, titanium dioxide - 24,39%, macrogol - 10,00%, kaio pua hao - 1,30%, ka hāleʻa hao hao wili - 0.3%, pōkole hao kelepona - 0,010%, wai maʻemaʻe. - qs

Dosis 5 mg + 500 mg:

Nā ʻāpana hoʻoikaika: glibenclamide - 5 mg, metformin hydrochloride - 500 mg.

Nukleus: sodium croscarmellose - 14.0 mg, povidone K 30 - 20.0 mg, microcrystalline cellulose - 54.0 mg, magnesium stearate - 7.0 mg.

Kahu: Opadry 31-F-22700 melemele - 12.0 mg: ʻaila pālua o ka lactose - 36.0%, hypromellose 15 cP - 28.0%, titanium dioxide - 20,42%, macrogol - 10,00%, kīwaha quinolika - 3.00%, hao keʻa puaʻa - 2.50%, ulaula pōpoki hao - 0,08%, wai maʻemaʻe - qs.

Nā palapala 2,5 mg + 500 mg: nā bopivex capsule ʻano like, i kālai ʻia me ke kala ʻulaʻula māmā, i kahakaha ʻia me "2.5" ma kahi ʻaoʻao.

5 mg + 500 mg dosage: nā kaponi ʻulaʻoni ʻoniʻoni nīnika i kālai ʻia
melemele lau, i hoʻopaʻa ʻia me "5" i hoʻokahi ʻaoʻao.

Ka hana lāʻau lapaʻau

ʻO Glucovans® ka hui pūpū o ʻelua mau pūhui hypoglycemic waha o nā hui lāʻau lapaʻau like ʻole: metformin a me glibenclamide.

Aia ʻo Metformin i ka hui o ka biguanides a hōʻemi i nā kiko o ka basal a me ka postprandial glucose i loko o ke koko koko. ʻAʻole ia e hoʻoikaika i ka metformin i ka huna ʻana i ka insulin a no laila ʻaʻole e kumu i ka hypoglycemia. He 3 mau hana i ka hana:

- hōʻemi ia ka hana o ka glucose i ka peka e ka pale ʻana i ka gluconeogenesis a me ka glycogenolysis,

- hoʻonui i ka ʻike o ka ʻoneka no nā peripheral i insulin, ka ʻai a me ka hoʻohana ʻana i ka maʻi glucose e nā ʻāpana i loko o nā uaua,

- ke kau nei i ka lawe ʻana o ka glucose i ka gastrointestinal tract.

He hana like ka metformin me ka glibenclamide hana like, akā hoʻopiha pū kekahi i ka hana hypoglycemic a kekahi. ʻO ka hui pūʻana o nā ʻaihue hypoglycemic ʻelua he hopena synergistic ma ka hoʻemi ʻana i ka glucose.

Lapaʻau lāʻau

ʻO Glibenclamide. I ka wa e lawe waha ʻia, ʻike ʻia ʻana mai loko mai o ka wahi gastrointestinal ma mua o 95%. ʻO Glibenclamide, kahi ʻāpana o ka lāʻau Glucovans® i micronized. Pahu ʻia ka pae kiʻekiʻe o ka plasma i kahi mau hola 4, ʻo ka nui o ke kahe ana he 10 mau lita. ʻO ke kamaʻilio me nā protein plasma he 99%. Ua aneane holoʻokoʻa ia i ke akeʻa me ka hoʻokumu ʻana o nā metabolites ʻelua, ʻoi aku

ua hoʻopā ʻia e nā keiki (40%) a me ka bile (60%). ʻO ka pau hoʻopau hapa-ola mai 4 a 11 mau hola. Ma hope o ka lawelawe waha, ua hoʻohuihui ʻia ka metformin mai ke kumu gastrointestinal pololei loa, ke kuhi ʻia ʻana o ka pīpī ma plasma i loko o 2 mau hola. Ma kahi o 20-30% o metformin e hoʻopili ʻia ma o ka gastrointestinal tract i loli ʻole. ʻO ka bioavailability kūpono mai 50 a 60%.

Hoʻolaha koke ʻia ʻo Metformin i loko o nā pā, hoʻomaʻamaʻa ʻole ia i nā protein plasma. Hoʻomili ʻia ia i kahi pae palupalu loa a hoʻopā ʻia e nā keiki. ʻO ka wehe hapa hapa-ola he awelika o 6.5 mau hola. I ka hihia o ka hana renal impaired, hoʻomaʻemaʻe ka hoʻomaʻamaʻa ʻana o ka renal, i ka mea e hoʻomaʻemaʻe ana i ka hana o ka creatinine, ʻoiai e pau ka hapalua hapalua o ke ola, e alakaʻi ana i ka piʻi ʻana o ka metformin i ka plasma koko. ʻO ka hui pū ʻana o ka metformin a me glibenclamide ma ke ʻano ʻano like me ka bioavailability like me ka lawe ʻana i nā papa i loaʻa nā metformin a i ʻole glibenclamide i ka hoʻokaʻawale. ʻO ka bioavailability o ka metformin i hui pū me ka glibenclamide ʻaʻole i loaʻa i ka ʻai kai, me ka bioavailability o glibenclamide. Eia nō naʻe, piʻi ka nui o ka emi ʻana o ka glibenclamide me ka ʻaina meaʻai.

Nā hōʻailona no ka hoʻohana ʻana

Pākuʻi type 2 i nā pākeke:

me ka loaʻa ʻole o ka hoʻohana ʻana i nā meaʻai meaʻai, ka hoʻomaʻamaʻa kino a me ka monotherapy o mua me ka metformin a i ʻole ka hopena o ke olalona.

e hoʻololi i ka lāʻau o mua i nā mea lapaʻau ʻelua (metformin a me derivative sulfonylurea) i nā mea maʻi me ka pae o ka glycemia pai a paʻa.

Nā Hoʻohui

hypersensitivity i ka metformin, glibenclamide a me nā derivatives sulfonylurea, a me nā mea kōkua, type 1 diabetes mellitus,

diabetes ketoacidosis, diabetes precoma, diabetes coma, renal failed or impaired renal function (ʻoi aku ka hana ma lalo o 60 ml / min),

nā hopena ākea e hiki ke alakaʻi i kahi loli i ka hana o ka aʻalolo: kūʻai, maʻi hōʻeha, ke neʻe, ka neʻe ʻana a me nā ʻāpana o ka iodine e ʻike ʻia (e ʻike i nā "Kūlana Nūpepa"),

nā maʻi akamai a i ʻole ke hele ʻia me ka maʻi hypoxia: puʻuwai a i ʻole ka hanu, ka hala ʻana o ka myocardial infarction, pīhoihoi, hōʻeha ate, porphyria,

hapai, ka manawa o ka umauma, ka hoʻohana pinepine ʻana o ka miconazole, ka hoʻokō nui,

humuhukuhū maoli, nā waiʻona hoʻoilo, lactic acidosis (me ka mōʻaukala o)

ka adherence i ka meaʻai haʻahaʻa-emi (emi iho ma mua o 1000 kaleka / lā),

ʻAʻole ia e hoʻohana i ka lāʻau i loko o nā kānaka ma mua o 60 mau makahiki o ka mea e hana i ka hana kino kino, a pili pū me ka piʻi nui o ka hoʻomohala ʻana i ka acidact lactic i loko o lākou.

Loaʻa i ka Glucovans® ka lactose, no laila ʻaʻole i ʻōlelo ʻia ka hoʻohana ʻana i nā mea maʻi me nā maʻi i loaʻa i nā mea āpau i pili i ka galactose intolerance, hemahema lactase a glucose-galactose malabsorption syndrome.

ʻŌpū a me ka lactation

Hoʻopili ʻia ka hoʻohana ʻana o ka lāʻau i ka wā hāpai. Hoʻomaʻamaʻa ʻia ka mea maʻi i ka wā o ka mālama ʻana me Glucovans®, pono ia e hoʻomaopopo i ke kauka e pili ana i ka hāpai ʻana a me ka hoʻomaka ʻana o ka hapai. Ke hoʻolālā nei i ka hapai, me ka mālama ʻana i ka wā hāpai i ka wā lawe i ka lāʻau Glucovans®, pono e haʻalele ʻia ka lāʻau lapaʻau a hoʻonā ʻia i ka lāʻau lapaʻau. Hoʻopili ke Glucovans® i ka umauma umauma, no ka mea ʻaʻohe hōʻike i kona hiki ke hele i ka waiū umauma.

ʻLoe a me ke kākele

Hoʻoholo ʻia ka nui o ka lāʻau e ke kauka ponoʻī no kēlā me kēia maʻi, e pili ana i ka pae o ka glycemia.

ʻO ka papa lāʻau mua he 1 papa o ka lāʻau Glucovans® 2,5 mg + 500 mg a i ʻole Glucovans® 5 mg + 500 mg hoʻokahi i ka lā. No ka hōʻalo ʻana i ka hypoglycemia, ʻaʻole pono ka nui o ka mua ma mua o ka nui o ka lā glibenclamide (a i ʻole ka hopena like o kekahi i lawe ʻia i ka sulfonylurea) a i ka metformin, inā ua hoʻohana ʻia lākou me ka lāʻau lapaʻau mua-mua. Ke manaʻo ʻia nei e hoʻonui ʻia ka nui o nā hoʻomoʻa ma mua o 5 mg o glibenclamide + 500 mg o ka metformin i kēlā me kēia lā 2 mau pule aʻe paha e kiʻi i ka pono o ka glucose koko.

ʻO ka hoʻoliʻi ʻana o ka hoʻokolohua hui ʻana me mua me ka metformin a me ka glibenclamide: ʻaʻole pono ʻo ka dosis mua i ka pākahi o kēlā me kēia lā o glibenclamide (a i ʻole ka hopena like o ka hoʻomākaukau ʻana o ka ʻaʻukui sulfonylurea) a me ka metformin i lawe ʻia ma mua. ʻO kēlā me kēia 2 a i hoʻokahi mau pule paha ma hope o ka hoʻomaka ʻana o ka hoʻōla, hoʻoponopono ʻia ke ʻano ma muli o ke ʻano o ka glycemia.

ʻO ka nui loa o ka lā i helu ʻia he 4 mau papa o ka lāʻau Glucovans® 5 mg + 500 mg a i ʻole 6 papa o ka lāʻau Glucovans® 2,5 mg + 500 mg.

Kau ka dosimen dosage i ke kanaka hoʻokahi:

No nā dosages o 2.5 mg + 500 mg a me 5 mg + 500 mg

• I ka lā hoʻokahi, i ke kakahiaka i ka ʻaina kakahiaka, me ka hoʻolālā o ka papa 1 i ka lā.

• ʻElua ʻelua i kēia lā, i ke kakahiaka a i ke ahiahi, me ke koho ʻana o 2 a 4 mau papa i ka lā.

No nā dosage o ka 2.5 mg + 500 mg

• ʻEkolu mau lā i kēia lā, i ke kakahiaka, ahiahi a me ke ahiahi, me ke koho ʻana o 3, 5 a 6 mau papa i ka lā.

No nā pākahi o 5 mg + 500 mg

• ʻEkolu lā i kēia lā, i ke kakahiaka, kakahiaka a me ke ahiahi, me ke koho ʻana o 3 papa i ka lā.

Pono e lawe ʻia nā papa me nā meaʻai. Pono ka papa ʻaina e hui me ka papa me ka nui o ka haʻalulu ai ka nui o ka puʻukū e pale i ka loaʻa ʻana o ka hypoglycemia.

Koho ʻia ka nui o ka lāʻau ma muli o ke kūlana o ka hana nui. ʻAʻole pono ʻo ka pā mua ma mua o ka papa lāʻau o ka lālani Glucovans® 2,5 mg + 500 mg. Pono ʻia ka loiloi maʻamau o ka hana hoka.

ʻAʻole ʻōlelo ʻia ʻo Glucovans® no ka hoʻohana ʻana i nā keiki.

Ke keu

Ma ka hihia o ka overdose, hiki i ka hiki ʻana ke hoʻomohala i ka hypoglycemia ma muli o ka hiki mai o kahi derivative o ka sulfonylurea i loko o ke ʻano o ka lāʻau (e ʻike i nā "Nā Manaʻo Manaʻo").

ʻO ka haʻahaʻa a maʻalahi i nā hōʻailona o ka hypoglycemia me ka nalowale o ka noʻonoʻo a me ka hōʻike neurological e hiki ke hoʻoponopono ʻia e ka ʻai koke o ke kō. Pono e hoʻokō ka hoʻoponopono a me / a hoʻololi i nā meaʻai. ʻO ka hōʻeha ʻana o nā hopena hypoglycemic koʻikoʻi i ka mea maʻi me ka maʻi maʻi, ka hele ʻana me ka coma, paroxysm, a i ʻole nā pilikia neurological, e pono ai ka mālama mālama olakino. Pono pono e lawelawe nei i kahi hopena dextrose pono ma hope o ka maʻi a me ka kānalua o ka hypoglycemia, ma mua o ka hoʻokipa ʻana i ka maʻi. Ma hope o ka ʻike hou ʻana, pono e hāʻawi i ka mea ʻai i ka mea maʻi i ka momona hoʻokaʻawale ʻia (i mea e pale ʻole ai ka hana hou o ka hypoglycemia).

ʻO ka overdose ka lōʻihi a i ʻole ka heleʻana o nā mea pili i hoʻopili ʻia e hiki ai ke hoʻonāukiuki i ka hoʻomohala ʻana o ka acidosis lactic, ʻoiai ʻo ka metformin he ʻāpana o ka lāʻau

Lactic acidosis kahi kūlana e koi ai i ka mālama ola olakino, mālama ʻia i ka acidosis lactic e lawe ʻia i loko o kahi keʻena. ʻO ke ala e ʻoi aku ka hopena maikaʻi loa no ka wehe ʻana i ka lactate a me ka metformin ka hemodialysis.

Hoʻonui ka Plasma glibenclamide hoʻomaʻemaʻe i nā maʻi i ka maʻi o ka naʻau. No ka mea pili ka glibenclamide i nā kahe koko, ʻaʻole i hoʻopau ʻia ka lāʻau i ka wā o ka dialysis.

Hoʻopili pū me nā lāʻau ʻē aʻe

Hoʻonui ka Plasma glibenclamide hoʻomaʻemaʻe i nā maʻi i ka maʻi o ka naʻau. No ka mea pili ka glibenclamide i nā kahe koko, ʻaʻole i hoʻopau ʻia ka lāʻau i ka wā o ka dialysis.

Hoʻonui ʻo Bozentan i ka hui me ka glibenclamide i ka piʻi o ka hepatotoxicity. Hōʻike ʻia e pale aku i kēia mau lāʻau i ka manawa like. Hiki ke emi iho ka hopena hypoglycemic of glibenclamide.

Pākuʻi me ka Metformin

Alika: Hoʻopilikia ka hopena o ka hoʻomohala ʻana i ka hoʻōho lactic acid me ka inu ʻawaʻawa o ka ʻawaʻawa, ʻoiai inā i ka pōloli, a i ʻole ka palaka maikaʻi, a i ʻole ka palupalu ʻana. I ka wā o ka mālama ʻana me Glucovans®, inu waiwa a me nā lāʻau lapaʻau e pili ana i ka waiʻona.

Hoʻohui ʻia me ka hoʻohana ʻana o nā mea āpau hypoglycemic āpau

ʻO Chlorpromazine: i nā helu kiʻekiʻe (100 mg / lā) e hoʻoulu i ka glycemia (hoʻemi i ka hoʻokuʻu o ka insulin).

ʻO ka mālama aku: pono e hoʻomaʻamaʻa i ka mea maʻi e pili ana i ka pono no ka mālama kūʻokoʻa o ka glucose koko, inā pono,

hoʻoponopono i ka mahele o ka ʻaihue hypoglycemic i ka manawa like o ka hoʻohana ʻana i kahi antipsychotic a ma hope o ka hoʻokuʻu ʻana o kona hoʻohana.

ʻO Glucocorticosteroids (GCS) a me tetracosactide: kahi hoʻonui o ka glucose o ke koko, i kekahi manawa me ka ketosis (GCS e hōʻemi a emi i ka hoʻohaʻahaʻa glucose.

ʻO nā kaʻina: pono e hōʻike ʻia ka mea maʻi e pili ana i ka pono no ka mālama kūʻokoʻa o ka hoʻokahe o ke koko, inā pono, e hoʻoponopono ʻia ke ʻano o ka maʻi hypoglycemic i ka wā o ka hoʻohana like ʻana o GCS a ma hope o ka hoʻopaʻa ʻana i kā lākou hoʻohana.

Loaʻa iā Danazole kahi hopena hyperglycemic. Inā pono ka mālama ʻana me ka danazol a i ka manawa i pau ai ka hopena, pono ʻia ka hoʻoponopono ʻana o ka lāʻau Glucovans® i lalo o ka hoʻomalu ʻana o ka pae glycemia.

Agonists Zr-adrenergic: ma muli o ka hoʻoulu ʻana o nā receptors Pr-adrenergic e hoʻonui i ka kao o ke kaila i loko o ke koko.

ʻO nā kaʻina: pono e lūlū i ka mea maʻi a hoʻopaʻa i ka kaohi o ka ʻona glucose o ke koko, ka hoʻololi ʻana i ka therapy insulin.

Diuretics: kahi nui o ka glucose koko.

Hoʻomaʻamaʻa: pono e aʻo ʻia ka mea maʻi e pili ana i ka pono no ka mālama kūʻokoʻa o ka hoʻokahe o ke koko, ka hoʻoponopono ʻana o ka maʻa ʻomaʻomaʻo hypoglycemic i ka wā hana me ka diuretics a ma hope o ka hoʻopau ʻana i kā lākou hoʻohana.

ʻO Angiotensin-hoʻohuli i ka enzyme (ACE) inhibitors (captopril, enalapril): ʻo ka hoʻohana ʻana o ACE inhibitors e kōkua i ka hōʻemi o ke koko koko. Inā kūpono, pono ke hoʻoponopono ʻia ke ʻano o ka Glucovans® i ka wā i hoʻohana pū ʻia aku me nā ACE inhibitors a ma hope o ka hoʻokuʻu ʻana i kā lākou hoʻohana.

Pākuʻi me ka Metformin

Diuretics: Lactic acidosis e kū ana i ka wā i lawe ʻia aku ka Metformin me ka hana ʻole ʻana i hana ʻia e ka diuretics, ʻo ia hoʻi ka diuretics loop.

Pili i ka hoʻohana o Glibenclamide

Z-adrenergic blockers, clonidine, reserpine, guanethidine a sympathomimetics mask kekahi mau hōʻailona o ka hypoglycemia: palpitations a me tachycardia, ʻo ka hapa nui o nā beta-blocker ākea e hoʻonui i ka ulu a me ka nui o ka hypoglycemia. Pono e hōʻike ʻia ka mea maʻi e pili ana i ka pono no ka mālama kūʻokoʻa ʻana i ka glucose o ke koko, ʻoi aku hoʻi i ka hoʻomaka ʻana o ka mālama ʻana.

Fluconazole: ʻO ka hoʻonui ʻana i ka hapalua-ola o ka glibenclamide me ka hiki ke loaʻa i kahi hōʻike o hypoglycemia. Pono e hōʻike ʻia ka mea maʻi e pili ana i ka pono o ka mālama pono ʻana i ka glucose i loko o ke koko, pono paha ia e hoʻoponopono i ka ʻai ʻana o nā lāʻau hypoglycemic i ka wā o ka mālama ʻana me ka fluconazole a ma hope o ka hoʻopaʻa ʻana i kona hoʻohana.

Pili i ka hoʻohana o Glibenclamide

ʻO ka Desmopressin: Hiki i ka Glucovans® ke hōʻemi i ka hopena antidiuretic o ka desmopressin.

ʻO nā lāʻau antibacterial mai ka hui o sulfonamides, fluoroquinolones, anticoagulants (dermaragine Coumarin), inhibitor MAO, chloramphenicol, pentoxifylline, lipid-hoʻemi iho i nā lāʻau mai ka pūʻulu o nā fibrates, disopyramides - ka hopena o ka hypoglycemia me ka hoʻohana ʻana o glibenclamide.

Nā hiʻohiʻona noi

E kue i kahi o ke ʻano o ka mālama ʻana me Glucovans®, pono ia e kiaʻi mau i ka pae o ka hoʻokeʻo no ka wikiwiki, a ma hope o ka ʻai ʻana.

ʻO ka maʻi lactic acidosis kahi ʻokoʻa a koʻikoʻi akā (ʻo ka make nui o ka make me ke ʻano o ka mālama ʻana i ka hana ʻoi aku ka hoʻopiʻi) e hiki mai ana ma muli o ka hōʻiliʻili o ka metformin. ʻO nā hihia o ka acidosis lactic i nā mea maʻi i mālama ʻia me ka metformin i hana nui ʻia i nā mea maʻi me ka maʻi mellitus me nā hana ʻole o ka pilikia.

ʻO nā mea ʻē aʻe e pili ana i ka pilikia, pono e noʻonoʻo ʻia, e like me ka ka maʻi maʻi kīnā ʻole, ka ketosis, ka manawa lōʻihi, ka ʻai ʻawaʻawa ka nui, ka make ʻana o ka naʻau, a me kekahi ʻano e pili ana i ka hypoxia koʻikoʻi

Pono ʻoe e noʻonoʻo i ka hopena o ka lactic acidosis me ke ʻano o nā hōʻailona nonspecific e like me ka ʻili o ka naʻau, i hui pū ʻia e nā maʻi dyspeptic, ʻeha o ka ʻeha a me nā malaise koʻikoʻi. I nā hihia koʻikoʻi, hiki ke hele mai ka acidotic shortness o ka hanu, hypoxia, hypothermia, a me ka coma.

He mau ʻōhua ʻai o ka diagnosty ʻo nā mea hoʻonaninani: nā haʻahaʻa pH koko haʻahaʻa, konsentrate lactate plasma ma luna o 5 mmol / l, hoʻonui anionic interval a me ka lactate / pyruvate ratio.

No ka mea ʻo Glucovans® e pili ana i ka glibenclamide, e lawe pū ana i ka lāʻau lapaʻau me ka hopena o ka maʻi hypoglycemia i ka mea maʻi. ʻO ka weheʻana i ka wai hoʻōla o ka hopena ma hope o ka hoʻomaka ʻana o ka mālama ʻana ke pale i ka hanana o hypoglycemia. Hiki ke kuhikuhi ʻia kēia ʻano maʻi i kahi mea maʻi e pili ana i ka pāʻina maʻamau (me ka ʻaina kakahiaka). He mea nui ia ka ʻaʻa kalapika e hana pinepine ʻia, ʻoiai ka pilikia o ka ulu ʻana o ka hypoglycemia e hoʻonui me ka papaʻaina o ka wā i hala ai, ʻaʻole i ʻole a i ʻole ka pale i ka paʻakai kalaiwa. ʻO ka hoʻomohala ʻana o ka hypoglycemia ka mea maʻamau me ka pākuhi hypocaloric, ma hope o ka hana koʻikoʻi a lōʻihi paha, me ka waiʻona, a i ʻole ka hui pū ʻana me nā mea maʻi hypoglycemic.

Ma muli o nā hopena uku e hiki mai ana e ka hypoglycemia, e lomo, me ka makaʻu, ka tachycardia, hypertension, palpitations, angina pectoris a me ka arrhythmia. ʻAno i hala paha nā hōʻailona hope inā ulu kū i ka hypoglycemia, i ka hihia o ka neuropathy autonomic a i ʻole e lawe ana i ka beta-blockers, clonidine, reserpine, guanethidine a sympathomimetics.

ʻO nā hōʻailona ʻē aʻe o ka hypoglycemia i loko o nā maʻi me ka maʻi maʻi hiki ke komo i ka hōʻeha, ka pōloli, ka nausea, ka luaʻi, ke kaumaha nui, ka hiamoe hiamoe, ka hoʻomāinoino, ka uluʻana, ka hopohopo a me ka noʻonoʻo psychomotor, me ka hopohopo, ka hilahila, ka haʻi ʻana i ka haʻi, ka blurred matakite, haʻalulu, hōʻeha a me ka paresthesia, dizziness, delirium, hoʻopiʻi, kānalua, ʻike ʻole, ʻike ʻole make, a me ka bradycardia.

ʻO ka mālama pono ʻana, ke koho ʻana i nā palena, a me nā ʻōlelo kūpono no ka mea maʻi he mea nui e hōʻemi i ka hopena o ka hypoglycemia. Inā mālama ka mea maʻi i ka hoʻoulu ʻana o ka hypoglycemia, ka mea i hōʻeha a pili paha i ka ʻike ʻole ʻana o nā ʻōpuhi, pono e noʻonoʻo ʻia ka mālama ʻana me nā mea maʻi hypoglycemic ʻē aʻe.

Hoʻokomo ka poʻe i ka hoʻomohala ʻana o ka hypoglycemia:

• Ka hoʻohana like ʻole o ka waiʻona, keu i ka wā wikiwiki,

• Ka hōʻole a (ʻole paha no nā poʻe maʻi maʻi) ʻaʻole hiki i ka mea maʻi ke launa pū me ke kauka a hahai i nā ʻōlelo koi i kuhikuhi ʻia i loko o nā ʻōkuhi no ka hoʻohana ʻana;

• Nā meaʻai kūpono, nā meaʻai kūpono, ka pololi a me ka loli ʻana o ka ʻai,

• He pale kaulike ma waena o ka hana hoʻokaumaha a me ka hana ʻai,

• Kāpē paʻakikī kūlā,

• Noho nui ʻia o ka lāʻau Glucovans®,

• nā koho endocrine i koho ʻia: hemahema ka hana ʻana o ka thyroid.

pituitary a me nā kūloko adrenal,

• ka mālama ʻana ʻana i kekahi mau lāʻau.

ʻO ka laupili o Renal a me ka pohō

Hiki i nā Pharmacokinetics a me / a i ʻole nā pharmacodynamics i loli i nā mea maʻi me ka maʻi hepatic a i ʻole ka hopena kino ʻole. Hiki ke hoʻonui ʻia ka hypoglycemia e loaʻa ana i kēlā mau maʻi, kahi e pono ai ke ʻano kūpono.

ʻO kahi Pūnaewele Glucose

Ma ka hopena o nā mea hana a i ʻole ke kumu o ka hoʻokaʻawale ʻana o ka maʻi maʻa, ua manaʻo ʻia e noʻonoʻo pono ʻia kahi hoʻololi iki o ka hoʻoliʻi ʻana i ka insulin. ʻO nā hōʻailona o ka hyperglycemia ke hoʻoiho pinepine, ka make nui loa, ka maloʻo maloʻo.

ʻO 48 mau hola ma mua o ke kaʻina hoʻolālā o ka hoʻomaʻamaʻa ʻana a i ʻole hoʻokele intravenous o kahi ʻenehana radiopaque iodine, i hoʻopau ʻia ka lāʻau Glucovans®. Hoʻoikaika ʻia ka hoʻōla ʻia ma hope o 48 mau hola, a ma hope wale nō ke loiloi ʻia ka loiloi a ʻike ʻia he mea maʻamau.

No ka mea, ua ʻoki ʻia ka metformin e nā keiki, a ma ka manawa maʻamau, pono ia e hoʻoholo i ka clearance creatinine a me / a i ʻole nā mea serum creatinine: ma ka liʻiliʻi he hoʻokahi i hoʻokahi makahiki i nā mea maʻi me ka hana o ka māla maʻamau, a ma ka manawa 2 mau manawa o ka makahiki ma nā mea maʻi , aia pū i nā mea maʻi me ka wehe ʻana o creatinine i ka palena kiʻekiʻe o kahi maʻamau.

Hoʻolaha ʻia ka mālama koʻikoʻi i nā hihia e loaʻa ʻole ai nā hana o ka pūpū, i ka laʻana, i nā mea maʻi maʻi, a i ʻole ia i ka hoʻomaka ʻana o ka lāʻau antihypertensive, ka hoʻohana ʻana i ka diuretics a i ʻole nā lāʻau o ka anti-inflammatory non-steroidal (NSAID).

ʻO nā hana ʻē aʻe

Pono ka mea maʻi e hoʻomaopopo i ke kauka e pili ana i ke ʻano o kahi maʻi bronchopulmonary a i ʻole he maʻi ʻeha o nā genitourinary organitions.

Hoʻokomo i ka hiki ke alakaʻi i kahi kaʻa a hana pū me nā mīkini

Pono e ʻike ʻia nā mea maʻi e pili ana i ka pilikia o ka hypoglycemia a pono e mālama i nā hana palekana i ka wā e holo a hana ana me nā hana pono e koi nui ai ka nānāʻana a me ka wikiwiki o ka hopena psychomotor.