Nā Papaʻohana Aila Kūpono ACC Kauka

ʻO ke ʻano dosage o ka hoʻokuʻu ʻana o Thrombopol i loko o nā pālani hāmeʻa i loko: pink, biconvex, ka pōʻai (i loko o nā pololi 10 o nā pcs.,

ʻO ka ʻōmole o 1 papa:

• mea waiwai: acetylsalicylic acid - 75 a 150 mg,
• nā mea kōkua: ka pauku palaoa, ke kōpala sodium carboxymethyl, microcrystalline cellulose,
• shell: hypromellose, Acrylic No ka hui ʻana no nā papa coating, ka hui ʻana o ka sodium lauryl sulfate, sodium hydrogen carbonate, methacrylic acid copolymer (type C), talc, triethyl citrate, titanium dioxide, colloidal silicon dioxide, crimson dye (Ponceau 4R).

Lapaʻau lāʻau

ʻO Thrombopol kekahi o nā NSAID ((non-steroidal anti-inflammatory drug), nā māka antiplatelet.

ʻO ke kumu o ka hana o ka hana acetylsalicylic acid ʻo ka hikiʻole ke hoʻololi ʻia o ka huaʻala o COX-1 (cyclooxygenase), ka mea e alakaʻi ai i kahi blockade i ke kāpili ʻana o ka thromboxane A₂ a me ka papa ʻana o nā hui platelet.

Ke hopena nei ka hopena antiplatelet ma hope o ka hoʻohana ʻana i nā hapa liʻiliʻi o ka lāʻau lapaʻau, ʻo ka lōʻihi o kona hopena ma hope o hoʻokahi pāheʻe he 7 lā. Hiki ke hoʻohana ʻia ka Acetylsalicylic acid e mālama i ka hoʻopale ʻana a me nā mea maʻi i lalo i nā maʻi: nā myocardial infarction, hoʻopiʻi i nā maʻi varicose, maʻi ʻeha coronary.

Eia kekahi, ʻo ka waiwai i loaʻa i ka hopena analgesic, anti-inflammatory a me ka antipyretic hopena.

Ma muli o ke kaupaona enteric o nā papa, hoʻokuʻu ʻia ka acetylsalicylic acid i loko o ka nui o nā mea alkaline o ka duodenum, e kōkua ana i ka hōʻemi o kāna hopena irritating i ka mucosa gastric.

Lapaʻau lāʻau

ʻO ka lawe ʻana aku o ka acetylsalicylic acid mai Thrombopol e hoʻomaka i nā hola 3-4 ma hope o ka lawe ʻana i ka lāʻau (hōʻoia kēia i ka hopena paʻa o ka haʻalele ʻana o nā papa i loko o ka ʻōpū). C_max (ka uka nui o kahi kinona) i ka nui o nā plasma he 6.72 a me 12.7 μg / ml (no nā papa o 75 a me 150 mg, kēlā,) kahi manawa e hōʻea ai ia ma kahi o 2-3 mau hola. ʻO ka hoʻopili ʻana o ka lāʻau e hoʻohiolo ana i ka heleʻana o ka meaʻai i ka ʻeha gastrointestinal.

ʻO AUC (wahi ma lalo o ka pihi ʻike-manawa) he 56.42 a 108.08 μg × h / ml (no nā papa o 75 a me 150 mg, ma kēlā).

ʻO ka Acetylsalicylic acid ka nui a komo koke i nā kīʻaha o ke kino a me nā mea he nui. ʻO ka palena o kona paʻa ʻana i nā protein plasma e hoʻoholo ʻia e ka ʻike.

ʻO ka hoʻoili pākuʻi paha ma kahi o 0.15-0.2 l / kg; e hoʻonui pū ana i ka manawa me ka hoʻonui o ka serum me ka thrombopol i loko o ke koko.

ʻAʻole e like me nā salicylates ʻē aʻe, e kū'ē ana i ke kua o ka hoʻokele hou ʻana o ka lāʻau, ʻaʻole i hōʻuluʻulu ʻia nā wai acetylsalicylic non-hydrolyzed.

ʻO ka hoʻoneʻe nui o ka acetylsalicylic i ka wā o ka hoʻoulu ʻana. Hōʻalo kēia kaʻina ma lalo o ka hopena o nā huina o ka pumehana i ka ate. Kūkulu ʻia nā metabolites i hope (loaʻa i loko o ka wai a me ka nui o nā ʻili): phenyl salicylate, glucuronide salicylate, a me ka limu salicyluric.

T_1/2 (hapalua-ola) o ka acetylsalicylic acid mai ke kaila koko ma waena o 15 a 20 mau minuke.

ʻO ka 1% wale nō o ka waha o ka waha e hoʻopuka ʻia ma ke ʻano o nā acetylsalicylic non-hydrolyzed e nā keiki, ʻo ke koena e like me ka salicylates a me kā lākou metabolites.

I ka hana ʻole ʻana o ka hana haki, 80-100% o hoʻokahi pākahi i hoʻopuke ʻia e nā ʻōpū ma loko o 24-75 mau hola.

ʻOi aku ka pae o ka metabolic i nā wahine (ma muli o ka hana haʻahaʻa o nā enzymes i ka serum koko).

I ka poʻe maʻi me ka hiki ʻole o ka renal, a me ka wahine hāpai a me nā keiki hou, hiki i ka salicylates ke haʻalele i ka bilirubin mai ka pilina me ka albumin, ka mea i hāʻawi i ka ʻano o ka bilirubin encephalopathy.

Nā hōʻailona no ka hoʻohana ʻana

• ka lani panghina,
• ʻO ka infarction myocardial waha (ke pale ʻana i ka maʻi myocardial mua ma mua o nā mea i hoʻopilikia ʻia, no ka maʻi mellitus, hyperlipidemia, hypertension arterial, obesity, ulaula, i ka wā ʻelemakule, me ka pale ʻana i ka myocardial infarction).
• ʻoi (pale, me ka poʻe maʻi me nā maʻi cerebrovascular transient)
• ka maʻi hōʻeha o ka cerebrovascular (prevention),
• ka thromboembolism (pale i ka wā postoperative a ma hope o ke komo ʻana o ka hoʻopiʻi ʻana ma luna o nā moku, inā, ka coronary artery bypass grafting, carotid artery endarterectomy, carotid artery angioplasty, arteriovenous shunting),
• thrombosis vein hohonu a me thromboembolism o ka pulmonary artery a me nā lālā ona (pale, e komo pū i nā mea maʻi ma hope o ka hoʻomohala nui ʻana i ka wā o ka immobilization lōʻihi).

Nā Hoʻohui

• ka hoʻonāukiuki ʻana o nā pilikia o erosive a me ka ulcerative o ka ʻili o ka gastrointestinal,
• ka hui pū ʻana o ka paʻa bronchial asthma, recurrent polyposis a paranasal sinuses / ihu and intolerance to acetylsalicylic acid,
• hemorrhagic diathesis,
• ka huhū haole,
• ka manawa like me ka methotrexate ma ke ʻano o 15 mg no hoʻokahi pule a ʻoi paha,
• Hoʻokomo ʻia ka bronchial asthma e nā salicylates a me nā NSAIDs,
• ʻO wau a me III trimesters o ka hāpai, a me ka wā o ka umauma,
• makahiki i 18 makahiki
• ka molowa ʻana o kēlā me kēia wahi o ka lāʻau, a me nā NSAID ʻē aʻe.

Relative (ʻo Thrombopol i kuhikuhi ʻia ma lalo o ka mākaʻi o ka lāʻau lapaʻau):

• polyposis o ka ihu,
• kohola
• nā maʻi hanu maʻi,
• pālahalaha maʻi
• kōleʻa / lawelawe kōleʻa
• ka mōʻaukala o nā ʻōpū a me nā ʻōpū duodenal a i ʻole ka ʻaihue a me ka ʻaihue,
• ʻOiaʻiʻo
• huhū maʻi
• Allergy allergy
• hoʻohana pū ʻana me anticoagulants,
• ka manawa like me ka methotrexate i loko o kahi pae o ka 15 mg i hoʻokahi pule,
• II trimester o ka hāpai.

Nā hopena hopena

• pānaehana hana: hoʻonui i ka hana o nā ʻalohi o nā ate, ka lua, ka luaʻi ʻana, ka ʻeha, ka ʻōpū o ka ʻōpū, ʻeha i ka ʻōpū, ka ʻōpū o ka ʻōpū o ka ʻōpū a me ka duodenum, me ka hoʻonaninani, ka hāwele o ka gastrointestinal,
• kikowaena Pūnaewele: tinnitus, dizziness,
• ea kalepa: bronchospasm,
• nā maʻi kūlike: ka edema o Quincke, urticaria,
• hematopoietic ʻōnaehana: hoʻonui i ke koko, ʻaʻole liʻiliʻi - anemia.

Ke keu

Hōʻike ʻia nā hōʻailona mua o ka overdose ma ke ʻano o ka nausea, ka luaʻi, ka tinnitus a me ka wikiwiki wikiwiki, a me ka neʻe ʻana, nā maʻi i lalo iho nei e ulu: ʻike i ka ʻike, lohe ʻole, ʻeha kahe, kolohe, ka hiamoe, hyperthermia, mea hōʻino. Me ka hoʻohālikelike koʻikoʻi, hiki paha i nā haunaele i ka wai-electrolyte a me ka hoʻāla kaulike-kumu (dehydration a me ka metabolic acidosis).

Hoʻomaka nā hōʻailona o ka palaka / hoʻohuihui hōʻemi ma hope o ka hoʻohanaʻana o 150-300 mg / kg acetylsalicylic acid. Hoʻopuka ka overdose koʻikoʻi me kahi kaʻe o ka 300-500 mg / kg. Nui paha ka momona o nā 500 mg / kg i kahi momona.

ʻAʻohe mea antidote kūikawā no ka thrombopol. Ma kahi lāʻau lapaʻau, i hiki ai i ka hōʻemi o ka lilo ʻana o ka lāʻau, hōʻike ʻia nā hana e like me: e hoʻoulu i ka lua a hoʻomāhaʻi i ka ʻōpū. Hoʻohana ʻia kēia mau hana no ka 3-4 mau hola ma hope o ka lawe ʻana i ka lāʻau lapaʻau, i nā hihia e lawe ai i ka ʻano nui, hiki i kēia manawa ke 10 mau hola. I mea e hōʻemi ai i ka komo ʻana o ka waiwai, pono e hoʻopili i kahi pakanā o ke kaʻa hoʻōla o ka carbon activated (ʻo nā pākeke makua - 50-100 g, nā keiki - 30-60 g), ʻoiai e nānā ana i ka pae o ka wai-electrolyte pono e hoʻokumu ʻia (inā pono, pono e hoʻoponopono hou ia i ka manawa manawa).

Ma ka hoʻomaʻamaʻa ʻana i ka waikawa a me ka hoʻōla ʻana i ka huehue o ka acetylsalicylic acid e nā keiki, ka nānā ʻana o ka paʻakai sodium bicarbonate, pono i mālama ʻia ka pH i ka pae o 7-7.

I nā hihia he nui loa ka hoʻohālikelike, hōʻike ʻia ka hemodialysis a i ʻole dialysis peritoneal.

Ma muli o ka hiki ʻana o ka acidosis respiratory, ʻae ʻia ka lāʻau lapaʻau e ʻoki ana i ka ʻōnaehana o ka hanana ma waena (e like me ka barbiturates) e pāpā ʻia. Ma mua o nā hopena o ka hanu, pono ia e hōʻoia i ka ala o ke airway a me ka loaʻa o ka oxygen. Inā pono, e hana i ka intubation intratracheal a hāʻawi i ka hoʻoweliweli uila.

Nā ʻōlelo kikoʻī

Hiki i ka Acetylsalicylic acid ke hoʻoulu i ka bronchospasm, me ke alakaʻi i ka hoʻouka a me ka maʻi a me nā hopena hypersensitivity ʻē aʻe. ʻO nā mea koʻikoʻi nā mea nui he mōʻaukala o ka bronchial asthma, hay fever, nasal polyposis, maʻi respiratory disease, alacism kūʻai i nā lāʻau lapaʻau ʻē aʻe (e.g. ʻano kūlohelohe, hōʻeha, hives).

Hiki i ka hoʻohana ʻana o ka acetylsalicylic acid ka mea e hōʻeha i ka nui o ka nui o ke koko i ka wā / ma hope o nā wawao. Ma kēia mau mea, 5-7 mau lā ma mua o ka hana i noi ʻia ʻia, pono e hoʻokuʻu ʻia ke ʻano.

Hoʻonui ka pilikia o ke koko me ka hoʻohana pū ʻana me ka thrombopol me nā anticoagulants, platelet aggregation inhibitors, a me nā lāʻau thrombolytic.

ʻO nā haʻahaʻa haʻahaʻa o ka acetylsalicylic acid i nā hihia o kahi predisposition (i hoʻemi ka uric acid excretion) hiki ke hakakā i ka gout.

Me ka hui pū ʻana o ka thrombopol me methotrexate, piʻi i ka ulu ʻana o ka hopena ʻino mai nā hui hematopoietic.

ʻO nā hopena kiʻekiʻe o ka acetylsalicylic acid e hoʻopuka i kahi hopena hypoglycemic, pono e mālama pono i nā poʻe maʻi me ka maʻi maʻi e loaʻa ana i nā lāʻau lapaʻau me kahi hopena hypoglycemic.

Me ka hoʻohana pū ʻana o ka glucocorticosteroids me thrombopol, ua mau ʻia ke emi ʻana i kona kao i loko o ke koko, a ma hope o ka hoʻopau ʻia o ka glucocorticosteroids, hiki i kahi kau salicylates.

ʻAʻole kuhi ʻia ka hoʻohana pono ʻana me ka ibuprofen, no ka mea e hōʻemi ana i ka pono o ka acetylsalicylic acid.

ʻO ka hui pūʻana o ka acetylsalicylic acid a me ka ethanol e hoʻonui i ka hōʻino o ka meaʻino i ka membrane mucous o ka gastrointestinal tract a lōʻihi ka manawa i hoʻokaʻawale manawa.

Hoʻokomo nui kahi overdose i ka poʻe maʻi maʻi. Ma muli o nā mea i hiki i nā mea maʻi ma luna o ke mau makahiki he 65, hiki paha ke hoʻokaʻawale i ka hana ʻoi aku, hiki i kēia pūʻulu o nā maʻi ke hāʻawi i ka thrombopol i nā hōʻemi kāwili ʻia.

ʻŌpū a me ka lactation

• ʻO wau a me III trimesters o ka hāpai ʻana: ua contraindicated ka hana ʻana, ka hoʻohana ʻana o Thrombopol i ka I trimester e alakaʻi ana i ka wehe ʻana i ka palate o luna a me nā hemahema o ka puʻuwai, i ka III trimester - e hoʻokaʻawale i ka hana, hana ka mua o ka ductus arteriosus i ka ʻōpū, hoʻonui ʻia ke koko i ka makuahine / fetus, ke koho koke ʻana i ka salicylates ma mua o ka manawa. hiki i ka hānau keiki ke hōʻeha i ka ʻōpū intracranial, aemaise i nā pēpē mua.
• ʻO II trimester o ka hapaha: hiki ke hoʻohana ʻia ʻo Thrombopol ma hope o ka loiloi ʻana i ka ʻike kaulike / ʻoi aʻe ka loaʻa ʻana o ka hopena.
• lactation: ua hoʻōla ʻia ka lāʻau.

Hoʻohui nūhou

Hōʻalo i ka hopena, e hoʻonui ʻia i ka hopena i hui pū ʻia me thrombopol:

• methotrexate: pili me ka hoʻokaʻawale ʻana i ka wehe ʻana i nā renal a me kona neʻe ʻana mai ka kamaʻilio ʻana me nā protein, ua contraindicated nā hui pū ʻana a pono paha e mālama ʻia (i ka wā e hoʻohana ʻia ai i nā ʻōmole ma luna a i ʻole 15 mg i hoʻokahi pule, he kumuhana).
• heparin a me nā helu anticoagulants: e pili ana i ka hana platelet i ʻole a me ka wehe ʻana o nā anticoagulants kūlike mai ka kamaʻilio ʻana me nā protein,
• nā hua lāʻau thrombolytic a me nā platelet aggregation inhibitors (ticlopidine),
• digoxin: pili me ka hoʻokaʻawale i loko o kāna hana renal,
• ʻO nā mea e kū ai ka hypoglycemic (a me nā derivatives o ka sulfonylurea): pili ia me nā waiwai hypoglycemic o ka acetylsalicylic acid iho i nā kūwaha kiʻekiʻe a me ka neʻe o ka derebatives sulfonylurea mai ka pilina me ka protein,
• valproic acid: ma muli o ka kaʻe o kona pili me nā protein,
• Nā NSAID
• sulfonamides (komo pū pūhū trimoxazole),
• pani ʻia
• paʻakai lithium.

ʻO nā hopena i hōʻemi ʻia kona hopena me ka hoʻohana pū ʻana me thrombopol:

• sulfinpyrazone, probenecid, benzbromaron a me nā mea hoʻohana anti-gout e hoʻonui ai i ka hoʻōla ʻana o ka uric: pili me ka hoʻokūkū tubular hoʻokūkū o ka uric acid,
• antihypertensive āpau, me ka angiotensin e hoohuli ana i ka enzyme inhibitors,
• antagonist aldoster (a make spironolactone),
• diuretics loop (ma ka furosemide kūikawā).

Nā hana ʻē aʻe ʻē aʻe:

• inu wai: hopena hoʻohui,
• glucocorticosteroids no ka hoʻohana ʻana i nā ʻōnaehana: e hoʻonāwaliwali i ka hana o ka thrombopol.

ʻO ka wehewehe ʻōlelo pōkole o ka lāʻau

Hoʻokumu ʻia ka thrombo ACC e like me nā papa papa liʻiliʻi keʻokeʻo i keʻokeʻo ʻia e hoʻopuni ʻia me kahi kaʻi ʻalipona e maʻalahi līlī ʻia i ka ʻili o ka ʻōpala. ʻAʻole ʻoi aku ka nui o ke ola o ka lāʻau lapaʻau ma mua o ʻekolu mau makahiki, pono ʻoe e mālama i ka pālāpū me ia mai ka lā. ʻO keʻano o ka lāʻau lapaʻau:

• mea kūlohelohe: acetylsalicylic acid, e like me kona kukuna, nā papa he 50 a 100 mg,
• nā mea kōkua.

Hāʻawi ʻia ka lāʻau lapaʻau i loko o ka pānaʻi ʻokoʻa me kahi kū ʻole o ka wai. Akā, pono e hoʻohana pono a ma nā inika i ʻōlelo ʻia ʻia. ʻAʻole makemake ʻia nā overdoses no ka ʻelemakule.

Hoʻokumu ka hopena o ka lāʻau lapaʻau e pili ana i nā hiʻohiʻona nui o ka wae kumu - ka salicylic acid: kahi hōʻemi i nā kaʻina hana, a me ka hoʻohaʻahaʻa i ka wela, a me ka hopena analgesic. Hoʻopau kona eter i ke kāpili ʻana o ka thromboxane A2 i loko o nā platelets, a laila e kōkua i ka pale ʻana i ka hoʻokumu ʻana o nā lolo koko. Hōʻike hōʻike ka hopena iā ia iho ma hope o ka hoʻohana ʻana i ka thrombo ACC a ua loaʻa i loko o 7 mau lā ma hope o ka lawe ʻana i hoʻokahi papa.

Nā hōʻailona no ka kuhikuhi ʻana i ka lāʻau lapaʻau

ʻO ka hopena i ʻike ʻia i ka hana o ka mea nui o ka lāʻau lapaʻau e ʻae iā ia e kuhikuhi no ka prophylaxis a me ka mālama ʻana (ʻelua monotherapy a me nā ʻano like ʻole) o ka myocardial infarction, ischemia, varicose veins. Ua hōʻike ʻia nā kumu nui o ka Trombo ACC:

• ka manele o ka angina pectoris,
• ʻO ka prophylaxis mua a me ka lua ma ka mālama ʻana i nā maʻi naʻau mai ka wā i loaʻa mai ai ka infococote myocardial, kaomi loa inā ua ʻike ʻia ka mea maʻi me ka maʻi mellitus, ka nui loa, nā hewa maikaʻi (ka nicotine a me nā mea inu wai), nā makahiki paʻa.

Hoʻohana ʻia ka hoʻohana ʻana o Thrombo ACC me nā lāʻau lapaʻau ʻē aʻe ma hope o ke kūkā kamaʻilio ʻana me ke kauka hele ʻana: hoʻonui ka papa i ka hopena o kahi mahele nui o ka mākaukau (me ka poʻe e pili ana i ka mālama ʻana i ka puʻuwai), no kēia kumu ka hiki ke ʻano o ka hoʻomaʻamaʻa ʻia o kēlā ʻano hanana.

Nā ʻōkuhi no ka hoʻokele pololei o ka thrombo ACC

Pono e kiʻi ʻia nā papa ma ke ao a i ke ahiahi paha, ma mua o ka ʻaina a holoi ʻia me ka wai nui. Ua kuhikuhi ʻia ʻo thrombo ma ke ʻano he papa, ʻo ka lōʻihi o ka mea e pono ai ke hoʻoholo e ke kauka ma muli o ka maʻi. Inā kōkua ka lāʻau lapaʻau a ʻaʻole ke kumu o nā ʻōiwi, a laila e hiki ke hoʻonui ʻia ka lōʻihi.

ʻO ke inu ʻana i ka Trombo ACC ma luna o kahi ʻōpū ʻole e pāpā ʻia loa.

ʻO ka maʻi maʻamau o ka lāʻau he 50-100 mg i kēlā me kēia lā. ʻO nā dosis momona (a hiki i ka 200 mg) i kuhikuhi no ka hana prophylactic o ka trombosis vein hohonu a me ka thromboembolism.

He ʻokoʻa loa ka pālahalaha o nā lāʻau no ka mea ʻoi loa ka liʻiliʻi o ka mea ikaika.

I ka poʻe o ka wā kiʻekiʻe, hiki i ka hoʻohana nui ʻana o ka nui o nā lākaʻi ke hoʻonāukiuki i kahi nui o ka hopena:

• hoʻomaopopo ʻole i ka ʻike a me ka hoʻonohonoho ʻana o nā neʻe;
• uha nui a me ka lua,
• nāwaliwali laulā
• huehue ka puʻuwai o ke kaumaha a me ke koko haʻahaʻa,
• pilikia ʻole a me ka hana hepatic.

I ka hoʻomaka mua o kahi overdose, lawa ia e lawe i ka arika, e hoʻomaʻemaʻe i ka ʻōpū a hoʻihoʻi i ke kaulike wai-electrolyte me nā mea lapaʻau a / a i ʻole nā ​​hopena kanaka. Ma kahi o kahi helu koʻikoʻi, ʻo ka hoʻokipa ākea me ka diuresis, hemodialysis, lavage o ka ʻōpū a me nā ʻōpū, pono e hoʻihoʻi hou ʻia ka hoʻāla o ka acid-base a me ka mālama mālama ʻana.

Nā lāʻau lapaʻau lāʻau o thrombo ACC

He nui nā koho a me ka thrombo ACC no laila, no laila ke koho ʻana i ka lāʻau kūpono kūpono e like me kona ʻano, he papa hoʻomalu, ʻo ka nui a me nā palena hiki ʻole ke paʻakikī.

Ke hoʻololi nei iā Thrombo ACC me nā lāʻau lapaʻau ʻē aʻe, pono ʻoe e kamaʻilio i kāu kauka no ka hoʻohuli ʻana me nā lāʻau ʻē aʻe.

Mea hana, hoʻokuʻu i nā mea, ka hoʻonohonoho, nā inikua, ka wehewehe

ʻO ka thrombo ACC e huahana ʻia e ka hale kūʻai lāʻau lapaʻau Austrian GL ʻO Pharma GmbH, nona nā mea kanu i loaʻa i ke kūlanakauhale o Pannach. Ma Lūkia, ʻo ka mākaʻi o Austrian pharmacists ka poʻe ʻoihana "Valeant", aia i kū i ka address: 115162, Moscow, st. Shabolovka, hale 31, kūkulu hale 5. Aia ma kēia kikoʻī hiki iā ʻoe ke hoʻouna aku i nā kīʻaha āpau e pili ana i ka lāʻau lapaʻau.

Loaʻa ka thrombo ACC i hoʻokahi kiʻi kaha - he nā papa wahaenteric coating film coating. Hoʻopili ʻia nā papa ma nā blisters (konvalyutki) i hana ʻia me ka alumini a me polyvinyl chloride, kahi, e kau ʻia i loko o nā pahu me nā lauke me nā palapala aʻoaʻo no ka hoʻohana ʻana. I nā pahu - 14 a 20 paha papa.

Loaʻa nā papa ʻaina thrombo ACC i ka acid acetylsalicylic e like me ka mea hana maʻa mau, i ʻike ʻia ʻo Aspirin. Akā ʻaʻole e like me ka Aspirin maʻamau me ka hopena antipyretic a me analgesic, ʻo ka huiʻana o Trombo ACC e pili ana i ka acetylsalicylic acid i kahi haʻahaʻa haʻahaʻa loa, e hoʻolako ana iā ia me kahi kūlana liʻiliʻi, ʻo ia hoʻi ka hopena antiplatelet. No laila, ma nā papa o thrombo ACC, pili ka acetylsalicylic acid i loko o ʻelua mau'āpana - 50 mg a 100 mg paha. Ua haʻahaʻa loa nā ʻōhua ʻelua, a no laila e hiki ke hoʻohana ʻia nā lāʻau lapaʻau wale nō, e like me ka ʻōlelo ʻana a nā kānaka, "hoʻēlo ʻia ke koko", ʻaʻole hoʻi e hōʻoluʻolu i ka ʻeha a hoʻemi ʻana i ke ea kiʻekiʻe. ʻOiaʻiʻo, inā makemake ʻoe, hiki iā ʻoe ke hoʻohana i ka thrombo ACC e hoʻohaʻahaʻa i ka mahana, akā no kēia, e lawe koke ʻoe i nā papa ʻelima, kahi e hoʻohālikelike ʻia i ka pākaukau i hoʻokahi papa o Aspirin maʻamau. A he kūpono kēia a pono ʻole.

Akā no ka hoʻohuli ʻana iā Trombo ACC me ka Aspirin maʻamau, hiki nō ke kī, no ka mea like ka nui o nā mea hana. Akā ma kēia hihia wale nō e māhelehele ʻia ka papa Aspirin i loko o nā ʻāpana a i ʻole hoʻi e kiʻi i ka nui o ka acetylsalicylic acid i 50-100 mg.

E like me nā mea kōkua, nā papa me ka pae ʻana o 50 mg a me 100 mg ka nui o nā mea like: microcrystalline cellulose, lactose monxidate, colloidal silicon dioxide a me ka māka lae. ʻO ka pūpū o ka 100 mg a me ka papa papa 50 mg ka mau pūʻali o nā mea like, ʻo ia hoʻi: talc, triacetin, a copolymer o ka methacrylic acid a me ka ethyl acrylate (1: 1) (Eudragit L).

ʻO nā papa o nā pā ʻelua (50 mg a me 100 mg) ka poʻe i hoʻokeo ʻia ke keʻokeʻo, loaʻa i kahi ʻano biconvex a poʻokeʻo, he pulu maalulu a i ʻole a hoʻoweliweli iki paha.

Thrombo ACC 100 a me 50

ʻOi pinepine, i loko o ka mau'ōlelo o kēlā me kēia lā, no ka leʻaleʻa, hoʻohui ʻia nā helu i nā inoa o nā lāʻau lapaʻau e manaʻo ʻia ana nā dosages o ka mea ikaika. Kahi ʻia ka hana like o nā inoa "hou", no laila ke hoʻomaopopo nei nā lāʻau lapaʻau, nā kauka, a me nā mea maʻi. Hoʻopili pololei kēia i ka thrombo ACC, i ka manawa inoa hou "thrombo ACC 100" a me "Thrombo ACC 50" e kuʻo wale nō ka hana o nā papa o ka lāʻau like.

ʻAʻohe mea ʻokoʻa, he ʻokoʻa ma kahi o ka inane o ka mea ikaika, ma waena o thrombo ACC 50 a me thrombo ACC 100, no laila ʻaʻole mākou e noʻonoʻo i ka lāʻau lapaʻau like kaawale me nā ʻano like ʻole. Ma nā mea ʻē aʻe, ma ke aniani ma lalo nei, e pili ana ka ʻike a pau e pili ana i ka thrombo ACC ma kekahi ʻāpana - ʻelua 50 mg a me 100 mg. A inā paha e pono e hoʻohālikelike i kekahi mau hōʻailona kūikawā a i ʻole nā ​​mana o kekahi ʻaha kikoʻī, a laila e hana mākou ma ke kumu, akā inā ʻaʻole ʻē paha nā ʻike a pau e pili ana i ka Trombo ACC ma nā papa ʻelua.

Hoʻolaha hopena

Loaʻa i ka thrombotic ACC kahi hopena antiplatelet, ka mea e hoʻemi ana i ka hoʻoneʻeʻana o nā platelets a me nā puna koko koko. Eia kekahi, ʻo ke kāpae ʻia o nā ʻāpana o ke koko i hoʻokaʻawale ʻia i waena o lākou a me ka paia o nā kīʻaha koko. No ke kumu o ia mea, ʻoi aku ka nui o ke koko, ʻaʻole ka palahalaha, maʻalahi a lūlū maikaʻi ma o nā moku, ʻaʻole paʻa, ʻaʻole hana i ka blockages. ʻO ka hopena antiplatelet o ka thrombo ACC ma muli o ka hoʻomaikaʻi ʻana i nā kahe kahe o ke koko ka mea e pale ai i ka hoʻokumu ʻana o nā koko koko i nā kīʻaha like ʻole, e hana ana i ka pale ʻana i nā kūlana koʻikoʻi nā hopena o ka pani ʻana o nā kīʻaha koko e ka thrombi (ka hōʻeha ʻana i ka puʻuwai, nā hōʻeha, nā tromboses, embolism pulmonary, a pēlā aku).

ʻO ka acetylsalicylic acid, ʻo ia kahi o ka thrombo ACC e like me ka mea hoʻohana ʻano ikaika ʻana, ʻo ia kekahi o nā mea hana e pili ana i ka antiplatelet. ʻO kāna hopena antiplatelet me ka nui o ka mīkini mau hana. No laila, pili ka acetylsalicylic acid i ka hana o nā ʻano like ʻole e hoʻoikaika i ka hana ʻana o kekahi mau mea a hoʻopaʻa i nā poʻe ʻē aʻe.

Ma kahi o ka hopena antiplatelet, ka acetylsalicylic acid ka hopena a me ka hopena fibrinolytic, aia i ka hoʻokaʻawale i nā koko koko i hana ʻia a kipi aku i nā sela koko hoʻokaʻaka. Hoʻopili ʻia ka waikawa Acetylsalicylic i ke kūlohelohe o nā kumu coagulation II, VII, IX, a me X i ke koko, kahi e hōʻemi ai i ka hoʻokumu thrombus.

No ka hoʻolālāʻana i ka hana fibrinolytic a me antiplatelet, lawe ʻia ka acetylsalicylic acid i nā wai haʻahaʻa - 75 - 325 mg i kēlā me kēia lā. ʻO ia ke kumu i loaʻa ai nā papa Trombo ACC i ka 50 mg a i ʻole 100 mg o ka acetylsalicylic acid. Ke hoʻomau nei ka hopena antiplatelet no hoʻokahi pule ma hope o hoʻokahi hoʻokahi manawa o ka nui o thrombo ACC.

ʻO ia ka mea i wehewehe ʻia o ka acetylsalicylic acid i hoʻohana ʻia e pale a mālama i ka hōʻeha ʻana i ka naʻau, maʻi puʻuwai coronary, ʻōwili o nā maʻi varicose a me nā maʻi ʻē aʻe e pōʻino ana no ka hoʻokumu ʻana i nā māka koko.

Ke lawe ʻia ʻana ma kahi o thrombo, e hoʻopili koke ʻia ʻo ACC. Mahalo i kaʻili enteric, ʻaʻohe papale i ka hoʻonāukiuki a me ka hopena o ka papaʻa i ka mucosa gastric. Ma hope o ka komoʻana i ke kahe, ua loli ka acetylsalicylic acid i ka acid salicylic, e hōʻike ana i kona hopena. Eia kekahi, neʻe iki ka salicylic acid i loko o ke ake me ka hoʻokumu ʻana o ka salicylate phenyl, salicylate glucuronide me ka salicyluric acid, kahi, e māhele ʻia i nā pōpuna a me nā kiko. Hoʻokomo ʻia ka waikawa Salicylic i ka waiū umauma a holo i ka pleka. I nā wahine, ʻoi aku ka wikiwiki o ka loli acetylsalicylic i loko o ke kino ma mua o nā kāne no ka wikiwiki o nā enzymes.

Hoʻopili ka Acetylsalicylic acid i ke ʻano o nā metabolites e nā keiki ma loko o 24 a 72 mau hola. ʻOiai me ka hoʻokele mau ʻana, ʻaʻole hōʻiliʻili ka lāʻau i ka serum koko.

Pehea e lawe ai?

Pono e lawe koke i nā papa nui thrombo ACC 50 mg a me 100 mg ma mua o ka ʻai ʻana, holoi ʻia me ka wai nui - ma ka liʻiliʻi o kahi aniani (200 ml). E hoʻomanaʻo ʻaʻole hiki iā ʻoe ke inu i ka thrombo ACC ma luna o ka ʻōpū ʻole, no ka mea hiki ke hōʻeha kēia i ka ʻeha a me ka ʻōpū. E ʻike e ʻai koke ma hope o ka thrombotic ACC. Ma ka manawa like, ʻaʻole i ʻōlelo ka huaʻōlelo "kaʻai" i kahi pākaukau paʻakikī, akā i ka hoʻohana ʻana i nā mea liʻiliʻi o ka meaʻai e hoʻopiha i ka ʻōpū. No ka laʻana, ma hope o ka lawe ʻana i ka thrombo ACC ua lawa ka ʻai ʻana i kekahi o nā maiʻa, kahi manikini, kahi puʻukū liʻiliʻi, huila liʻiliʻi, a pēlā aku, a ua lawa kēia e pale ai i ka hopena hoʻonāukiuki i ka ʻōpū.

ʻO nā ʻōpio Trombo ACC pono e hoʻopau ʻia i ko lākou āpau, ʻaʻole i wāwahi, ʻūhā, nahu, a ʻeha paha i nā ala ʻē aʻe.

E like me ke kānāwai, ua lawe ʻia ka thrombo ACC hoʻokahi lā i kēlā me kēia lā. Hoʻomaopopo ʻia e lawe i ka lāʻau lapaʻau i kēlā me kēia lā i ka manawa like - no kēia pono wale ʻoe e koho i kahi kikoʻī i ke ao a inu mau ka lāʻau i kēia manawa. He mea maʻalahi ia no nā poʻe he nui e lawe i ka Thrombo ACC ma mua o ka ʻaina kakahiaka, aʻo nā mea'ē aʻe e makemake i kēia hana i ke ahiahi ma mua o ka hiamoe. ʻO ka manawa hana o ka lawe ʻana i nā papa, e hilinaʻi nui loa i ka hōʻoluʻolu o ka mea maʻi. Akā e hoʻomanaʻo ʻia i kēlā me kēia manawa i ka lāʻau e inu ai, koke ma hope o ia e pono ai e ʻai i kahi meaʻai liʻiliʻi.

Kuhi ʻia nā papa o ka thrombo ACC no ka hoʻohana ʻana ma ke ʻano lōʻihi, a ua hoʻoholo ʻia e ke kauka ka lōʻihi o nā papa lāʻau lapaʻau. Ua kuhikuhi ʻia kekahi i kahi kaohi mau ʻana o ka thrombo ACC no 6 mau mahina a i ʻole paha i kekahi mau makahiki, a hāʻawi ʻia kekahi i nā papa no ʻekolu mau mahina me ka haki o 2 a 4 mau pule ma waena o lākou. Ma hope o nā hana, hiki ke kuhikuhi ʻia ʻo thrombo ACC no hoʻokahi mahina wale nō. Akā i ka laulā nui, kuhikuhi pinepine ʻia ka Trombo ACC no ke ola, ʻoiai inā he ʻeha a ke kanaka no ka trombosis a me ka paio ʻana o nā ʻehā like ʻole me ka thrombi, a laila ʻaʻole ia e nalo a noho ana a hiki i kona make ʻana. I mea e pale ai i ka hoʻokumu ʻana o nā koko koko a me ka wehe ʻana o nā kīʻaha koko e lawe ʻia ana ka thrombo ACC no ka manawa lōʻihi, ke ʻole, inā he ʻano koʻe nui kekahi o ka maʻi thrombosis.

Paena no nā maʻi like ʻole

ʻO ke kumu o ka thrombotic ACC e hilinaʻi nei no ke kumu ua lawe ʻia ka lāʻau lapaʻau.

No laila, no ka pale ʻana i ka infarction myocardial prim a hoʻomaʻi, pono ʻia ʻo thrombo ACC e 50-100 mg i kēlā me kēia lā (1 papa 50 mg a i ʻole 1 papa 100 mg ka hoʻokahi i ka lā).

Ma ka mālamaʻana i ka angina kūlia a paʻa i ka thrombo ACC e ʻōlelo ʻia no ka lawe ʻana i ka 50-100 mg i kēlā me kēia lā. No laila, pono ʻoe e inu i hoʻokahi papa o 50 mg a 100 mg hoʻokahi i ka lā.

No ka pale ʻana i nā hōʻeha a me nā hanana loea cerebrovascular, ua noi ʻia ʻo thrombo ACC e lawe i ka 50-100 mg i kēlā me kēia lā (1 papa 50 mg a i ʻole 1 papa 100 mg hoʻokahi i ka lā).

Ke kāohi nei i ka thromboembolism ma hope o kekahi hōʻeha a ma hope o nā intervtion intervities pili i ka lawe ʻana i ka thrombo ACC ma 50 - 100 mg i hoʻokahi lā (1 papa o 50 mg a i 1 papa papa o 100 mg hoʻokahi i ka lā).

No ka pale i ka trombosis vein hohonu a me ka thromboembolism o ka pulela a me kāna mau lālā, ʻoiai ʻo Thrombo ACC e ʻōlelo e lawe i 100-200 mg i kēlā me kēia lā (1 a i ʻole 2 mau papa o 100 mg hoʻokahi i ka lā).

Hoʻohana i ka wā hāpai a me ka umauma

ʻO ka hoʻohana ʻana i ka acetylsalicylic acid i loko o nā malama ʻekolu o ka hānau ʻana i hiki ai ke hoʻonāukiuki i nā hemahema hoʻomohala i loko o ka pūpū, e like me ke kiʻekiʻe palate kiʻekiʻe ("cleft palate"), nā puʻuwai puʻuwai, etc. ʻO ia ke kumu e lawe ai i nā lāʻau lapaʻau e pili ana i ka acetylsalicylic acid, me ka thrombo ACC, i hoʻohālikelike ʻia i ka wā mua o nā wiki he ʻumikūmālua.

Ke lawe nei i ka hoʻomākaukau ʻana i ka acetylsalicylic acid i loko o nā helu he ʻoi aku o 300 mg i ka lā mai ka 27 mau pule o ka hāpai ʻana a ma mua o ka hānau ʻana i ka wā e hoʻonāukiuki i ka hana ʻana, hoʻonui i ke koko i ka makuahine a me ka maʻi fetus, a me nā hana mua o ka wehe ʻana o ka naʻau i ka pūpū. Hoʻomaopopo ka kaila acetylsalicylic koke ma mua o ka hānau keiki, hiki ke hoʻonāukiuki i ka hemorrhages intracranial i loko o kahi pēpē, ʻoi aku ka mana o ka wī ma mua. ʻO ia ke kumu i lawe ʻia ai i nā lāʻau lapaʻau me ka acetylsalicylic acid i ke kolu o ka hapakolu o ka hapai.

I ka lua o ka hapalua o ka hāpai ʻana, ʻo ia hoʻi, mai ka lā 14 a hiki i ka pule 26, e komo pū ana, hiki ke lawe ʻia ʻo Trombo ACC wale nō i nā hōʻike hōʻike koʻikoʻi, i ka mea nui loa ia no ka makuahine ʻokoʻa, a inā he pōmaikaʻi ka nui o nā mea āpau hiki. I ka wā ʻelua o ka hapahapa o ka hapai ʻana, ʻae ʻia ka hoʻohana ʻana o ka thrombo ACC i nā papa pōkole.

Ka huehue Acetylsalicylic a me nā mea kikoʻī i loko o ka waiū umauma. Akā ʻo ka hoʻokele ʻaʻole i hōʻeha ʻia o ka acetylsalicylic acid ma mua o ka mea ʻaʻole ia e hoʻopiʻi i ka hopena a i ʻole nā ​​hoʻopiʻi ʻana i nā pēpē, ma muli o ka mea e ʻae ʻia nei ka thrombo ACC i ka wā o ka ʻōpū. Eia nō naʻe, inā e lawe lōʻihi ʻia ʻo Trombo ACC, a laila ʻoi aku ka maikaʻi o ka hoʻomaʻamaʻa ʻana e hōʻoki ae hoʻoneʻe i ke keiki i nā ʻano mea kanu loiloi.

Hoʻopili pū me nā lāʻau ʻē aʻe

ʻO ka thrombotic ACC, i ka wā i hoʻohana pū ʻia, e hoʻomaikaʻi i ka hopena o kēia mau lāʻau penei:

• Methotrexate (hoʻemi i ka excretion o ka methotrexate e nā keiki),
• Anticoagulants (Heparin, Warfarin, etc.), thrombolytics (Urokinase, Fibrinolysin, etc.) a me nā mea e pili ana i ka antiplatelet (Clopidogrel, Curantil, etc.). I ka wā i lawe aku ai me Trombo ACC, ka hopena makai o ka membous mucous o ka ʻōpū a me nā ʻōpū, e piʻi aʻe ana, a ke piʻi aʻe o ka pilikia o ke koko,
• Nā mea koho serotonin reuptake inhibitors (Fluoxetine, Venlafaxine, Elicea, Valdoxan, Flunisan, Oprah, etc.) - ke kūʻē o ke kahe mai ka ʻōpū a me ka esophagus e hoʻonui,
• ʻO Digoxin - ua hoʻemi ʻia kona excretion e nā keiki, i hiki ke alakaʻi i kona overdose,
• ʻO nā hua o ka sulfonylureas e hōʻemi i ke kō o ke koko (Glibenclamide, Glycvidone, Glyclazide, Glimepiride, Glipizid, Chlorpropamide, Buformide, Nateglimide, etc.) - ke emi ka nui o ka glucose i ka nui, mai ka wā i hoʻēmi iki ʻia ana ʻo Thrombo ACC.
• ʻO ka hoʻomākaukauʻana i ka wai momona Valproic (Konvuleks, Depakin, Dipromal, Valparin XP, etc.) - ke uluʻana o ka maʻi o ka valproate,
• ʻO nā mea inu ʻawaʻawa a me nā lāʻau inu alakino - ʻoi aku ka hōʻino o ka hōʻino o ka ʻili o ka ʻōpū a me nā ʻōpū, a ʻoi aʻe hoʻi ka manawa i ke koko.
• ʻO nā lāʻau anti-inflammatory nonsteroidal (Diclofenac, Nimesulide, Indomethacin, Meloxicam, etc.) a me nā salicylates ʻē aʻe (Salofalk, etc.) - ka hopena o ka ulu ʻana o nā ʻōpū o ka ʻōpū a me nā ʻōpū duodenal a me ke koko e hoʻonui.

Hoʻoikaika ka hoʻohana ʻana o Thrombo ACC me nā lāʻau lapaʻau e hiki mai ana i ka hopena (no laila, pono paha ke hoʻonui o kā lākou ʻai)

• ʻO kekahi lāʻau lapa diuretic (ma lalo o ka hana a thrombo ACC, ka helu o ka kānana ʻana i ka urine e nā keiki, e emi ana)
• Nā mea hoʻohālikelike o ka angiotensin-hoʻohuli i ka enzyme (Captopril, Kapoten, Perineva, Prenessa, Enalapril, etc.) - ua hoʻomāaloʻo ʻia ka hopena o nā inhibitor ma ka hoʻohaʻahaʻa i ke koko a hoʻohele ʻia ko lākou hopena cardioprotective. ʻO ka pinepine, ʻo ka hoʻohaʻahaʻa i ka ulu o ka hana o ka angiotensin-hoʻololi lono e mālama ʻia i ka wā e mālama ʻia ana lākou me Thrombo ACC i kahi pane ma mua o 160 mg i kēlā me kēia lā,
• Ke hōʻemi nei i nā huaʻai e hoʻoikaika ai i ka ʻōhina o ka uric acid (Probenecid, Benzbromaron) - i ka hopena o ko lākou hopena ma muli o ka hoʻolohi ʻana o ka pūpū,
• Nā ʻōnaehana glucocorticoid System (prednisone, dexamethasone, etc.) - ke hoʻonui nei ka paʻahao o ka thrombo ACC, a ua nāwaliwali kā lākou hopena.

Nā hopena hopena

Hoʻomaʻamaʻa maikaʻi ʻia ʻo thrombo ACC a, ma muli o ke ʻano haʻahaʻa o ka acetylsalicylic acid, ʻaʻole ia he hopena o ka hopena. Eia nō naʻe, ma nā hihia līlū, hiki i ka thrombo ACC ke hoʻonāukiuki i ka holo ʻana o nā ʻano like ʻole o nā hopena like ʻole mai nā ʻokoʻa ʻē aʻe a me nā ʻōnaehana:

1. Mai ka gastrointestinal tract:

• Kahula
• Lohea
• Lōkuhi
• ʻEha ka ʻōpū
• ʻO ka ʻōkuhi aiʻole ka ulule duodenal,
• ʻO ka pīhoihoi Gastrointestinal
• Ua hana ka maʻi lēwa holoʻokoʻa me ka hana nui o ka aspartate aminotransferase (AcAT) a me alanine aminotransferase (AlAT).

• ʻʻAla
• Ke hoʻolohe ʻia nei
• Tinnitus.

• ʻO ka helu koko kiʻekiʻe i ka wā a ma hope o ka hōʻoki ʻana,
• ʻO ka maʻamau hematoma formation,
• Nā ʻōhola pinepine
• Kūpono paila
• Kahe koko ʻana
• ʻO nā hemorrhages Cerebral (aia ka palena kiʻekiʻe i ka poʻe maʻi e lawe iā Warfarin a i ʻole nā ​​anticoagulants i ka manawa like, a ʻaʻole hoʻi e kaohi i ke koko, akā e piʻi mau ana ka mea).
• ʻO ka posthemorrhagic hopena a i ʻole a emi ʻole ka hao i ka anemia ma muli o ke koko okana.

• ʻIli ka ʻili
• ʻO ka ʻili
• ʻĀpio,
• ʻO ka makeʻe o Quincke,
• Allergic rhinitis
• Ka ʻā ʻana o kahi o ka mucosa mucal.
• Bronchospasm (kahi kikoʻī ikaika o ka lumen o ka bronchi me ka loaʻa ʻana o kahi sensation o ka hoʻokō)
• ʻO ka maʻi kaumaha o Cardio-respiratory,
• Anaphylactic pīhoihoi.

Pehea e lawe ai i ka thrombo ACC - ma mua a i ʻole ma hope o ka ʻaina.

Ma hope o ka kipa ʻana i ke kauka, ʻike ka mea maʻi i kahi inoa hou no ka lāʻau lapaʻau i ka papa inoa kuhikuhi. ʻO ka manawa aʻe, ʻo ka mea maʻamau, ua hoʻopili ʻia kahi ʻōlelo pōkole, e hōʻike ana i ka helu o hoʻokahi o nā wai lapaʻau, hoʻonui ʻia e ka nui o nā dosa i kēlā me kēia lā. I kekahi mau hihia, lawa kēia ʻikepili, akā ʻaʻole wale i ka wā e pono ai ʻoe e lawe i ka TromboASS.

ʻOiaʻiʻo, hiki iā ʻoe ke ʻike i ke aʻo ʻana e pehea e lawe ai i nā papa kiola ʻo thrombo ACC no ka ʻōpio ʻana o ke koko, aia mau ia kahi ʻaoʻao - "ʻāpana hana", e hōʻike ana i ka wā e hana ai i kēia, ma mua a i ʻole maʻa o ka ʻaina. Akā ʻaʻole e hōʻino i ka mea hōʻiliʻili, hana ʻia kahi ʻano aʻo ia no kahi kamaʻāina kūlike ʻole. Ma hope aʻe, he papa inoa o nā contraindications, ma kahi aneane ʻike ʻia e ka poʻe ka liʻiliʻi i kekahi o kāna "ʻeha".

Ma hope o kēlā, hoʻomaka ka hoʻopiʻi e pili ana i ka mālama luhi ʻana, a me ka hōʻoluʻolu ʻana hoʻi o ke kauka hele mai, hoʻomaka. ʻO ka neʻe nui loa ka "ventricles," a me ke kūʻokoʻa kūʻokoʻa i nā analogues ʻaʻole i loaʻa nā waikawa.

No laila ʻo wai ka mea hewa? Kauka? A i ʻole i ke ʻano loea i hoʻolālā i ka palapala e pili ana i ka lāʻau lapaʻau? Hiki ke loaʻa ka pane ma ka nānā ʻana i nā ʻōlelo aʻoaʻo i ka pauku i wehewehe ʻia ai ka kikoʻī o ka papa hoʻokahi.

He aha ka mea i hoʻokomo i ka hoʻomākaukau o ka thromboass?

ʻO ka hapa nui o kēia lāʻau lapaʻau, ʻoiaʻiʻo, ʻo ka acetylsalicylic acid. ʻO kēia ka mea i loaʻa i ka poʻe maʻi e loaʻa ʻole i ka ʻōpū o ka ʻōpū.

Akā ʻaʻole hoʻi e poina iā mākou, ʻaʻole e like me ka ASK maʻamau i kūʻai ʻia ma ka pākeke, nā pānaʻi manamana koko TromboAX e paʻa ana me kahi pūlei i loaʻa nā mea e like me ka talc a me ka eudragit.

sc name = "info2 ″ text =" I ka molekole o ka talc, ʻo ia kahi o ka pulupulu, aia ka magnesium - he mea e neʻe ai ka hopena make o ASA ma ka epithelium o ka ʻōpū. "

ʻO Eudragits kahi kumumana o ka polymerization o ka acrylic acid. Hana lākou i nā hana o ka halihali ʻana i ka lāʻau i kekahi ʻāpana i kikoʻī mua i ka ʻawaʻī, pale iā ia mai nā hopena o ka ʻōpū o ka ʻōpū a me ke kō.

Akā, he mea pono e pili ana i nā contraindications. ʻO kēia ka "hui pūpū" inā nele ka mea maʻi, "ʻaʻole ma luna o ka ʻōpū ʻole" a "me ka hoke ʻole", nā huakaʻi hele "me ke akahele" a "ʻaʻole i ʻōlelo ʻia."

E hoʻokuʻu i ke ʻano, ka hoʻonohonoho ʻana a me ka pōpoki

ʻO nā papa thrombopol enteric-coated, ʻulaʻula ma ka ʻulaʻula, he mau mea hoʻoikaika i kapa ʻia ʻo Acidum acetylsalicylicum. Wahi a nā loiloi o Trombopol, ua hōʻike ʻia kahi lāʻau lapaʻau ʻano hona i loko o kēia mau helu e hōʻike nei - he kanahikukumamālima mau haneri a me kanalima milligrams. E like me nā mea kōkua, ua hoʻohana ka mea hana i nā kōkaʻai palaoa, MCC, atria amylopectin glycolate. Aia i ka kinikini kekahi mau māhele - Hypromellosum, kahi hui kūikawā no ka pani ʻana i ka lāʻau me ka E553b, ka mea hoʻoulu ʻia ka meaʻai E171, triethyl citrate, ka mea pili kala, Silicii dioxydum colloidale, Natrii hydrocarbonas, sodium lauryl sulfate. ʻO ke kumu kumukūʻai o Trombopol he 51 mau rubles. Hiki ke loaʻa i ka ʻike ma ka loaʻa ʻana o ka lāʻau lapaʻau ma o ke kelepona a i ʻole ma ka pūnaewele o ka mea hoʻolaha alawale.

ʻO ka heleʻana ma lalo o ka kinipona, ʻike ʻoe i ka hoʻopili me ka ACS, ka pūnaehana o ka hana ikaika e kau ai:

• lactose
• cellulose
• wai silika
• kalaka kākāʻau.

Hoʻokumu ʻo Lactose i kahi ʻāina ulu no ka lactobacilli, paʻa i ka hoʻonohonoho ʻana o nā microflora o ka ʻōpū. Hoʻomaʻemaʻe ʻo Cellulose i nā palupā o nā toxins. Hoʻopili a Silicon a kāpae i ka bilirubin mai ke kino, a laila hoʻokaʻawale i ke koko. ʻO ka kōkō kuiki e hoʻohaʻahaʻa i ka waikawa a hoʻonui i ka pale ʻana.

sc name = "info2 ″ text =" Ma nā mea kūlohelohe, liʻiliʻi ka ʻike o kēia mau mea i loko o ka papa pākahi. Akā i ka manawa i kauoha ʻia ai ka lāʻau lapaʻau, e like me ke kānāwai, no ka manawa lōʻihi, nui ka helu e hōʻuluʻulu ʻia a pili ʻia.

I ka wehewehe ʻana i ke kumu o nā mea āpau o ka lāʻau, a hoʻi mākou i ka nīnau kumu. Pehea e lawe ai i ka thromboass, a he mea koʻikoʻi loa ia i ka wā e lawe ai i nā paila - ma mua a i ʻole maʻa o ka ʻaina.

Kūpaʻa ka hopena o nā paila i ka nui, ka maikaʻi a me ka manawa o ka ʻai kai?

Ua hōʻike ʻia nā haʻawina i hoʻokele ʻia ma kēia pilikia:

1. Hoʻoneʻe ka hapa nui o ASA i loko o ka ʻōpū liʻiliʻi, a i ʻole, i kona ʻaoʻao i luna.
2. ʻAʻole paʻa ka manawa o ka hāhiu ʻana i ka kiʻekiʻe o ka piha o ka ʻōpū.
3. ʻO nā hui e hoʻohaʻahaʻa i ka waʻa o ka wai gastric ʻaʻole i pā i ka wikiwiki o ka assimilation o ke kino o ka lāʻau. Hiki i ka like ke like me ka waiū a me nā huahana ʻē aʻe e loaʻa ana nā momona holoholona.

Eia hou, huli mākou i nā ʻōkuhi, kahi i ʻōlelo ʻia e pono ai e lawe ʻia nā papa thrombo ACC ma mua o ka ʻai ʻana, akā ʻaʻole ma ka ʻōpū ʻole. Me ka manaʻo o ka meaʻai ʻaʻole e hoʻopilikia i ka hana o ka lāʻau lapaʻau, ʻokoʻa ʻia.

Maʻa mau ia e hoʻomaopopo i ka mea "ʻaʻole ma ka ʻōpū ʻole"?

Mai inu koke i nā papa ma hope o ka hiamoe. Pono ka ʻōpū i ka manawa e loaʻa ai ka hana. Inā, no kekahi kumu, ʻo ka hapa mua o ka lā ka koho maikaʻi loa no ka lawe ʻana i ka lāʻau lapaʻau, a laila pono ʻoe eʻai mua i kekahi mea. ʻO ia ka mea liʻiliʻi o ka meaʻai, akā e lawelawe ia i ka ʻōpū e like me ke kauoha - "e hoʻomaka".

ʻO ka thromboass no ke koko haʻalulu, i lawe ʻia ma kahi "ʻōpū palupalu," me ka ʻai ʻole o ka ʻai i loko, ua hoʻopau ʻia nā pōpilikia i loko o ka ʻōpū. Me ka hoʻonui nui o ka acidity, e hoʻomau ka hapa nui o ASA i ka hoʻonā wai, e hoʻonui ana i ka hopena irritating i nā cell epithelial. Me ka hoʻohaʻahaʻa ʻana i ka nui o ka ʻōpū, ua hoʻohuihui ʻia ka ASA i nā paia o ke aʻa o ka huina a hōʻuluʻulu ʻia i loko o nā pūpū o ka membrane o ka mucous, kahi mea i makemake ʻole ʻia.

sc name = "info" text = "Pono ʻoe e lawe i ka Tromboass ma kahi kikoʻī, i hiki ʻole ke ʻōlelo ʻia ma ke ʻano he" ma hope o ka ʻai ", a i ʻole" ma mua. "

E like me ʻoe e hoʻomaopopo ai, ua pili kēia mau luhi ʻana āpau, no ka hapa nui, me ka pale o ke kaomi kūwili ʻana, mai nā hopena maikaʻi ʻole o ka ASA, a ʻaʻole e hoʻopilikia i ka hopena ʻokiʻoki i ka lāʻau lapaʻau.

Pehea e hana ʻia ai ke kahuna ʻokoʻa?

Hoʻokomo ʻia i loko o nā paia o ka pūpili liʻiliʻi, nā mea ikaika o ka lāʻau lapaʻau e komo i ke kahe koko a hoʻopaʻa i nā hāmeʻa. Hōʻike ʻia ka ASA e ka waiho ma waho o nā pū. Akā pū pū kekahi me ka protein, ʻaʻole e nalowale kāna hana.

ʻO ASA e hoʻohālikelike i ka thromboxane - kahi enzyme i hūnā ʻia e nā platelets hoʻōla ʻia, ka mea e hōʻailona ai ka hoʻōla ʻana o nā platelets ʻē aʻe. Deactivated platelets, a hiki i ka hopena o ke ola o ko lākou ola, e nalo i ko lākou hiki ke hōʻuluʻulu, e kōkua ana e hoʻōki i ke koko.

Kahi mea waiwai o ka ASA i loko o ka lāʻau lapaʻau, ʻaʻole paha e ʻike ʻia ka lāʻau lapaʻau ma ka heluna āpau i ke koko koko (a i loaʻa paha i nā pae liʻiliʻi loa). Akā, no ka mea, e hōʻike nui ʻia ka hopena pale i ka hana o ka platelet.

sc name = "info" text = "Ma ka hoʻokaumaha ʻia o nā ʻōpū o nā ate, ua hoʻonohonoho ʻo ASA i kahi" ʻikepili "ma luna o nā platelets ma aneʻi. "Ke lawe nei ka ʻōnaehana uila iā lākou ma ʻaneʻi, kahi i ʻike ʻia ai lākou i ka pae piha o ka lāʻau."

Ke kū nei i ke kahe o ka emi o ke koina o ka thromboxane, ʻo ka manaʻo o ka prostacyclin, he antagonist o ka platelet activation enzyme, e ala ana i loko o ke koko. No laila, ʻo ka hopena e pono ai a pono e loaʻa ai - ka ʻokiʻoki i ke koko.

No ka mea ua ʻōlelo ʻia e lawe i ka Thrombo ACC e hoʻokaʻawale i ke koko, e holoi ana i nā papa me nā wai he nui a me nā wai wai ʻē aʻe, ua ʻike kēia i ka manawa o ka hana - ma mua o ka ʻai, a ʻaʻole hoʻi ma hope. ʻO ka meaʻai, me ka mea nui o ka wai wai, e hoʻopiʻi i ka hana o ka ʻōpū a hoʻolā i loko o ia mea i kahi manawa lōʻihi.

Ma ke kānāwai, ke kauka nei ke kauka hoʻokahi i ka lāʻau hoʻokahi o ka lāʻau, me ke koi ʻana no ke ahiahi. I kēia, pono e nānā kekahi i nā hilinaʻi huna a hūnā ma nā biorhythms o ke kino a i ʻole nā ​​kumu waiwai ʻē aʻe.

ʻO ke manawa o ke ahiahi, ma mua o ka ʻaina ʻaina, ʻoi aku ka nui o nā manaʻo noʻonoʻo. ʻO kēia ka wā i hopohopo ai ke ʻano o ke ao, ke holo wikiwiki, ua lapuwale. Loaa ke kino, ʻo ia hoʻi ma ka lolo, he manawa pōkole loa mai nā hopohopo waho a hiki iā ia ke kuhikuhi pono iā ia iho. ʻO kēia kahi kūlana ʻoluʻolu maikaʻi no ka lawe pololei ʻana i nā paila.

sc name = "info2 ″ text =" Ke hōʻike ʻia nei ka ʻike ʻana i ka papa holoʻokoʻa, ʻaʻole wale ka hopena i ka hopena i ke kino, akā e hoʻopau ʻia nā huahana nāu āpau. "

Inā kānalua ka mea maʻi e pili ana i ka pilina o ka lāʻau lapaʻau. Inā i ka wā o ka mālama ʻana i nā maʻi hōʻeha e kū ai i loko o ka ʻōpū, nausea, dizziness, lilo ka ikaika. E hui koke ʻoe me kāu kauka.

I ka hihia, ʻaʻole pono ʻoe e hoʻololi kūʻokoʻa i ka nui o ka lāʻau a i ʻole e hoʻowalewale i ke hoʻololi ʻana i ka ThromboASS me nā analogue. ʻO kēia kahi o nā poʻe loea i loaʻa ka ʻike pilikino e pili ana i ke kūlana maʻamau o ke kino o ka mea maʻi, i hōʻiliʻili ʻia ma ke kumu o ka hoʻokolokolo a me ka nānā ʻana, me ka noʻonoʻo ʻana i nā mea kūʻokoʻa.

Ka hana lāʻau lapaʻau

Ua hōʻike ʻia nā noiʻi hauoli i, e like me kona mau kikowaena, thrombopol a paʻa koke ke kālai ʻana mai ka ʻuʻina ʻana. ʻO ka acetylsalicylicum Acidum ka waiwai e hoʻohuli i ka acid phenolic. ʻO ka nui o ka waika o ka acetylsalicylic i loko o ke kaila koko i hoʻopaʻa ʻia ma ka awelima ʻumikūmālima mau minuke ma hope o ka lawe ʻana i ka lāʻau, hōʻea ka metabolite ikaika i kahi kaila nui ma loko o kanakolukūmākahi haneli mau minuke. Ma muli o ka hoʻonui nui o ka pūliki papa, ua hoʻokuʻu ka hoʻokuʻu ʻana o ke kumu ikaika o ka lāʻau i loko o ka ʻōpū. Hāʻawi kēia waiwai o ka waiwai i ka mea i kahaki ʻia o ka waiwai ikaika - mai 180 a 360 mau minuke. ʻO ka hāmeʻa ikaika a me ka metabolite ikaika e loaʻa i ka waiwai o ka hoʻopaʻa ʻana i nā protein plasma. Eia kekahi, nā hiʻohiʻona i kau inoa ʻia e kahi pālahalaha wikiwiki i nā kiko. ʻO ka 2-hydroxybenzoic acid ka waiwai i hoʻopuka ʻia i loko o ka waiū umauma. Hōʻike nā hopena o nā hoʻokolohua i komo ka metabolite ma o ka pāpaʻa placental. Kuhi ʻia ke kāpae ʻia ma ke ʻano hana i kuhikuhi ʻia. Me ka liʻiliʻi o ka lāʻau lapaʻau, lawe ka hapalua-ola mai 120 i 180 mau minuke. I kahi hopena kiʻekiʻe, ʻo T1 / 2 he ʻumikumamālima hola. ʻO ka mea hoʻāliʻi o ka salicylic acid ka mea nui ma o nā keiki. Hiki iā ʻoe ke kauoha i ka thrombopol mamao. ʻO ia ka mea hana i kēia mau waiwai: • kāohi i ka hoʻohui platelet, • pale i ka kāpili ʻana o ka thromboxane A2. Aia kekahi mau ʻōlelo aʻoaʻo o nā ala ʻē aʻe e hana ai i ka acetylsalicylicum Acidum ma ke kaukau ʻana o ka platelet, no laila ke hana ikaika ka lāʻau i ke ʻano o nā maʻi maʻi vascular. Aia nā NSAID ma waena o lākou, a loaʻa ka acetylsalicylic acid i ka hopena paʻakikī: • hōʻoluʻolu i ka hōʻeha, • hoʻohemo i ka wela, Hoʻohana ʻia ka paʻakikī o ka mea hana, e like me ka mea i hōʻike ʻia ma ka wehewehe, a ua hoʻohana ʻia no ka maʻi ʻeha o ka maʻi ʻeha, a me ka leʻaleʻa e hoʻokaʻalulu i kēia mau hōʻailona iho: a me ka ankylosing spondylitis.

ʻO Thrombopol, e like me ka hōʻike ʻana i nā ʻōkuhi, ua kuhikuhi ʻia i ka poʻe maʻi me nā maʻi e hiki mai ana: • ka angina pectoris o kahi ʻano paʻa ʻole, • e like me ka huakaʻi o ka ʻeha, ʻo ia hoʻi i nā mea maʻi me nā kuhi o ka lolo, i kahi ʻano transient, • i mea e pale aku ai i ka AMI, ʻoiai inā he moʻolelo kekahi o nā mea i hoʻohālikelike ai i ka maʻi - diabetes, ke koko kiʻekiʻe, nā hana ʻino, ʻo ia hoʻi ka ulaula, i nā poʻe maʻi o nā makahiki ʻelemakule (mai 65 mau makahiki), dyslipidemia, mau hihia hou o MI, • prolact i ka huʻi blockage o ke koko moku ma ka thrombus, e uhai aku, mai ko lakou wahi o ka hoʻonaʻauao 'ana, ka oi aku ma hope oʻoki lāʻau lapaʻau a invasive vascular, pulmonary embolism • Kāohiʻana, • ka Kāohiʻana o ka huʻi-hoouka kaua kāna hana ma ka lolo hana o vascular ka molekumu o, hoikeia mea nui, cerebral a hui symptoms.

ʻLoe a me ke kākele

ʻO ka Trombopol no ka hoʻohana waha. Manaʻo ka mea hana i ka ʻai ʻana i ka lāʻau i loko o ka papa ma hope o ka ʻai, me ka luku ʻole ʻana i ka kūpaʻa. Hoʻoholo ʻia ka nui o ka make, me ke ʻano hoʻoponopono hoʻomālamalama ʻia i ka mōʻaukala a me ka hōʻeha o ka maʻi: 1. Inā kuhi kekahi iā MI i kahi ʻano maʻi, mai hoʻokahi haneri a me kanalima ʻelima mau miligram o ka mea ola e kuhikuhi ʻia. Manaʻo ka mea hana i ka huki ʻana i ka papa mua i ka wā e ʻike ʻia ana nā hōʻailona mua. ʻO ka hoʻonāukiuki i ka membrane enteric ka mea e wikiwiki ai i ka hopena o ka lāʻau. No ka mahina aʻe e pono ai, e lawe nā mea maʻi mai 75 a 300 milligrams i kēlā me kēia lā. Ma hope o ke ʻano o kahi papa lapaʻau e pono ai, pono ke kauka i ke kauka i ka pono o ka hoʻokele hou ʻana o ka lāʻau, i mea e pale ai i nā hihia hou o nā maʻi. 2. No ka poʻe maʻi i hōʻeha i ka MI, e hōʻemi i ka hōʻemi o ka morbidity, a me kahi hopena momona hiki, e loaʻa ana i ka nui o ka lāʻau lapaʻau ma ka pae o 75-300 milligrams. 3. I ka mea i kapa ʻia ʻo ka angina pectoris o kahi ʻano paʻa a paʻa ʻole, pono ʻoe mai i ka kanahikukūmālima a i ʻekolu haneri mau mililami o ka waiwai ikaika i kēlā me kēia lā. 4. ʻO ka poʻe maʻi e pilikia ana no ka hoʻomohala ʻana i nā hōʻailona o MI ma ka hoʻohālikelike me ka maʻi diabetes, ke koko kiʻekiʻe, ke koʻikoʻi, a ʻo nā makahiki ʻelemakule hoʻi e ʻōlelo ʻia i hoʻokahi haneri a me kanalima milligrams o ka mea hana i kēlā me kēia lā a ʻekolu paha mau milligram i kēlā me kēia lā. 5. I mea e pale ai i ka ulu ʻana o ka lua, ua pono ʻoe mai ka kanahikukūmālima a ʻekolu haneri milligram o ke ʻano ikaika i ka lā. 6. Hoʻohana ʻia kahi papa hana maʻamau i kēlā me kēia lā e mālama i nā poʻe maʻi me nā hōʻailona o ka neʻe ʻana i ka ischemic attack, a me kahi kūlana stroke concomitant a me ke ʻano he prophylaxis no ka pani ʻana i kahi kīʻaha koko ma o ke kaaka koko i hōʻea mai kona wahi i hoʻomohala ʻia ma hope o ke kaʻina hana a me nā hana hōʻemi. 7. Hiki iā ʻoe ke pale aku i ka DVT a me ka thromboembolism me Trombopol ma ke kauʻana o 75 a 200 milligrams i kēlā me kēia lā. ʻO kekahi ʻano hana lapaʻau e ʻae ʻia, e hoʻohana ai i ʻekolu mau miligram i kēlā me kēia lā. E hoʻohuli, me ke ʻano he kānāwai, ma hope o ka ʻoihana nui. I nā mea maʻi me ka hana maʻamau o nā keiki a me ka pēpē i ke ʻano maʻalahi a me ka maʻalahi, e pono ai ke hoʻoponopono ʻia ʻana o ka lāʻau.Hiki iā ʻoe ke kūʻai iā Trombopol ma kahi kikowaena hale o nā lāʻau lapaʻau a me nā ʻahahui pūnaewele.