Pehea e hoʻohana ai i ka Canon Metformin?

Loaʻa ka lāʻau lapaʻau i ke ʻano o nā papa kiʻi ʻoniʻoni. Aia nā papa he 500 mg, 850 mg a me 1000 mg o ka metformin.

Nā papa nui me ka nui o 500 mg e puni, a me nā papa me nā kaha he 850 mg a me 1000 mg (Metformin lōʻihi) oval.

Loaʻa ka lāʻau lapaʻau i ke ʻano o nā papa kiʻi ʻoniʻoni.

1. Metformin hydrochloride.
2. Polyethylene glycol (macrogol).
3. ʻO Povidone.
4. Talii.
5. Sodium stearyl fumarate.
6. ʻO ka māhu Sodium carboxymethyl.
7. ʻO ke kumu a pregelatinized.
8. ʻO Opadry II keʻokeʻo (hoʻohemo i ke ʻano kiʻiʻoniʻoni).
9. Kaapili Titanium.
10. Ka waiʻona Polyvinyl.

Ka hana lāʻau lapaʻau

Hoʻopili ka Metformin i ka gluconeogenesis, ke kō o ka waikawa momona kūlohelohe, a me nā kaʻina o ka lipolysis (hōʻeha momona) a me ka momona oxidation. I ka manawa like, hoʻāla ʻia ka nui o ka glucose i ke kino ma o ka hoʻonui ʻana i ka naʻau o nā mea pili i nā insulin.

ʻO ka lāʻau lapaʻau ka mea e hoʻoponopono ai i nā kiko o nā triglycerides a me ka cholesterol i ke koko. Ke lohi nei i ka emi ʻana o ka paona i nā mea maʻi obese.

Hoʻomaopopo ʻia ka lāʻau lapaʻau i mua o ka thrombosis, no ka mea he hopena fibrinolytic. Kōkua ʻo Metformin e kāpae i nā koko koko i loko o nā moku koko.

Hoʻomaopopo ʻia ka lāʻau lapaʻau i mua o ka thrombosis, no ka mea he hopena fibrinolytic.

Lapaʻau lāʻau

A lawe ʻia ma ke alo, lawe lō ʻia ka lāʻau mai ke kaʻe ʻana o ke kaomi. ʻO ka hoʻoneʻe ʻana o ka metformin he 50%. ʻAʻoleʻoi aku ka bioavailability ma kahi o 60%. Ua hiki i ka waiwai i kona kao i loko o ka plasma i loko o nā hola 2-2.5.

Hoʻopili paʻa ʻo Metformin iā albumin koko, akā hoʻokomo koke i nā ʻōloʻomaʻi o nā ola mua. Ke hoʻokaʻawale ʻia nei ia mai ke kino e ka nunui a loli ʻole ʻia. Ka wā manawa i ka wā 8-12 mau hola.

No ke aha ka mea i kuhikuhi ai?

Ua kuhikuhi ʻia ka lāʻau lapaʻau no nā pākeke a me nā keiki ma mua o 10 mau makahiki mai ka momona a me ke ʻano type diabetes mellitus (non-insulin-dependant). Hiki i ka lāʻau lapaʻau ke hoʻohana pū me ka lua a me ka lua (ʻo ka hui pū me ka insulin).

ʻO nā hōʻike ʻē aʻe no ka hoʻohana ʻana:

1. ʻO ka momona hepatosis (ate dystrophy). ʻO kahi maʻi kahi e hoʻohuli ai ka maʻi hepatocytes (nā aho pili) i ka lipid tissue i loaʻa.
2. ʻŌnuʻi līpū polū. Hāpai pinepine ʻia kēia pathology me ka nui o ka pale ʻana i ka insulin. Over-production o kēia hormone a me ka hoʻonui nui 'ana i ke kō kōʻai koko e loaʻa.
3. Hāpopo. Hōʻike ʻia ka maʻi e kahi kiʻekiʻe o ka lipids a me nā lipoproteins i ke koko.

ʻO ka hōʻikeʻana no ka hoʻohana ʻana he hepatosis momona.

Nā Hoʻohui

Hoʻokomo ʻia ka lāʻau lapaʻau i nā maʻi aʻe:

• intolerance pilikino e metformin a iʻa nō iʻa,
• coma maʻi maʻi
• hoʻōki hoʻoliʻi,
• maʻi ʻino ʻeha
• huakaʻi renal function,
• nā hopena ʻino a me ka luaʻi paha,
• maʻi maʻi hopohopo nui
• hypoxia
• fiva
• sepsis
• anaphylactic haʻalulu,
• myocardial infarction
• i ka hanu ʻana a i ʻole ka naʻau hemahema,
• waiʻona
• lactic acidosis,
• ka hemahema calorie
• keiki malalo o 10 makahiki.

Hoʻopilikia ka lāʻau lapaʻau ma ka hihia o kēlā me kēia intolerance e hui i nā metformin a i nā mea hoʻokalakupua.
Hoʻokomo ʻia ka lāʻau lapaʻau i ka sepsis.
Hoʻokomo ʻia ka lāʻau lapaʻau i ka waiʻona.
Hoʻokomo ʻia ka lāʻau lapaʻau i nā kūlana febrile.

Lawe i ka lāʻau lapaʻau no ka maʻi maʻi maʻi

Wahi a nā ʻōkuhi, ua kuhikuhi ʻia nā pākeke me ka monotherapy i ka 1000-1500 mg o ka lāʻau i kēlā me kēia lā. Inā pono, hoʻonui ʻia ka nui o kēlā me kēia lā i 2000 mg. ʻO ka nui loa o ka lā i helu ʻia he 3000 mg o metformin. Hiki ke hoʻokaʻawale ʻia ka nui o ka lā i kēlā me kēia mau dosis 2-3.

Ke hui pū me ka insulin, ʻo ka make o Metformin he 1000-1500 mg i kēlā me kēia lā. I ka wā ʻoi, hiki ke koi ʻia kahi hoʻoponopono insulin.

Pehea e lawe ai no ka lilo nui?

No ka mālamaʻana i ka momona, ke kumu o ke kū'ē o ka insulin, ua kuhikuhi ʻia ka lāʻau lapaʻau ma kahi inikua mua o 500 mg hoʻokahi. Hoʻonui ʻia ka nui i ka 2000 mg i kēlā me kēia lā, e hoʻohui ai i ka 500 mg i kēlā me kēia pule.

Kōkua ka Metformin e hōʻemi i ka paona i ka wā e hui pū ai me ka meaʻai kūpono.

Kōkua ka Metformin e hōʻemi i ka paona i ka wā e hui pū ai me ka meaʻai kūpono. Akā, ʻaʻole hiki ke hoʻopili ʻia kahi meaʻai paʻa ma muli o ka pilikia o ka hypoglycemia.

Mai ka ʻaoʻao o ka metabolism

Ka hopena i ka metabolism:

• lactic acidosis,
• Ka nele o ka B12 (hoʻemi ʻia ka ʻaihue waiū).

Hiki i ka lāʻau ke hōʻemi i ka makemake.
Hiki i ka lāʻau lapaʻau ke alakaʻi i kahi anorexia.
Hiki i ka lāʻau lapaʻau ke kumu i ka hoʻomohala ʻena.
Hiki i ka lāʻau lapaʻau ke alakaʻi i nā hopena kūlohelohe.

Nā ʻōlelo kikoʻī

Ma mua o nā hana hana a me nā hoʻokolohua e hoʻohana ana i nā lāʻau radiopaque, kahi oki ʻia ka lāʻau lapaʻau. Lawe ʻia ka lāʻau lapaʻau i nā lā 2 ma mua o ka hoʻokolokolo a laila hoʻomau ʻia ma hope o 2 mau lā.

Ma mua o ka wehe ʻana, he kāpae ʻia ka lāʻau lapaʻau.

Hoʻohana i ka wā hāpai a me ka lactation

ʻOiai ʻo ke mea ikaika e hele ma waena o ka plasenta, ʻaʻole i ʻōlelo ʻia ʻo nā wahine hāpai e lawe i kēia lāʻau lapaʻau. ʻAʻole i lawe ʻia nā noiʻi paʻa ʻana o nā hopena teratogenic o nā metformin. I kekahi manawa kākau nā kauka i kēia lāʻau lapaʻau i nā wahine hāpai inā pono.

Hoʻomaopopo ʻia ka male ʻana i ka wā lapaʻau e pani.

Ke noi no ka hana renal haukapole

Haʻi ʻia ka lāʻau e lawe ʻia i nā keiki ma mua o 10 mau makahiki ma lalo o ka nānā ʻana o kekahi kauka.
Hoʻohana ʻia ka hoʻohana ʻana i ka lāʻau no ka hana renal impaired.
ʻAʻole kuhikuhi ʻia ka lāʻau no nā poʻe kahiko (ma hope o 60 mau makahiki) ma muli o ka nui o ka nui o ka hopena o ka lactic acidosis.

Hoʻopili pū me nā lāʻau ʻē aʻe

Ua lawe ʻia ka lāʻau pono me ka mālama ʻana me kēia mau lāʻau lapaʻau.

1. Danazole (kumuhana hyperglycemic).
2. Chlorpromazine.
3. Hoʻopuka i nā ʻike.
4. Nā hua palapala o nā sulfonylureas.
5. Nā NSAID.
6. PolohanaHula.
7. ACE inhibitors a me MAO.
8. Nā Hoʻolaka.
9. Nā lāʻau lapaʻau maʻi (e komo pū ana i nā kūmole waha).
10. Diuretics (mai ka hui o thiazide a ihi diuretics paha).
11. ʻO nā hua o ka waikela nikotinic a me nā phenothiazine.
12. Hoʻolau.
13. ʻO Cimetidine.

Ke lawe nei i ka lāʻau lapaʻau i nā papa kiʻekiʻe, hiki ke palupalu.
Lawe ʻia ka lāʻau pono me ka mālama me ka lāleka ʻo Danazol.
He hōʻemi maikaʻi ʻole ka lāʻau i ka waiʻona.

Inā pono kēlā mau hui, e hoʻoponopono ke kauka i ka maʻa o ka lāʻau a mālama i ka ʻaila o ke kō a me ka lactic acid i loko o ke koko.

Hoʻolaha ka waipuna

He maikaʻi ʻole ka huahana o kēia huahana me ka waiʻona. Hoʻonui ka alapona i ka pilikia o ka hypoxia kiko, lactic acidosis a me nā hopena ʻē aʻe.

ʻO nā analogues kaulana o kēia huahana nā Glucophage (Merck Sante, Palani), Formmetin (Pharmstandard, Russia), Siofor (Berlin-Chemie, France). Ke loaʻa nei kēia mau lāʻau i ka hana like like - metformin hydrochloride.

ʻO nā lāʻau lapaʻau e like me Metformin Teva a me Metformin Richter he mau generics. Hoʻohālikelike lākou i ka Metformin Canon i ka hoʻonohonohoʻana a me ka hana, akā ua hoʻopuka ʻia e nā mea hana ʻē aʻe.

Nā Hōʻikeʻike Metonin Canon

Konstantin, 42 makahiki, St.

Ua hana wau ma ka endocrinologist ma mua o 10 mau makahiki. Ua kuhikuhi ʻia kēia lāʻau lapaʻau no nā mea maʻi me ka maʻi maʻi a me ka momona. Kōkua ia i ka hoʻomaʻamaʻa i ka metabolism a me ke kiʻekiʻe o ka glucose koko. ʻIke pinepine wau i nā hopena ʻaoʻao i kaʻu hana.

Irina, 35 makahiki, Krasnodar

ʻO Metformin kahi mea lapaʻau hypoglycemic maikaʻi i ka mālamaʻana i ka maʻi diabetes 2 ʻano. E hoʻomanawanui maikaʻi koʻu mau maʻi i kēia mau lāʻau. Ma hope o kahi mahina o ka lawe ʻana i ke kōhi koko koko. I mea e pale ʻole ai i ka ʻōpū o ka ʻōpū, ʻōlelo wau ʻaʻole lawe i ka lāʻau lapaʻau ma ka ʻōpū ʻole.

ʻO nā kōkō haʻahaʻa hoʻohaʻahaʻa ʻo MetforminMetformin kiʻi maoli

Valentine, 56 makahiki, Belorechensk

Ua aʻo wau e pili ana i nā lāʻau olakino e like me Metformin, Siofor, Glucofage mai kahi endocrinologist. Ua koi ʻo ia iā lākou e hakakā i ka maʻi maʻi. Loaʻa ka maikaʻi o Metformin me ka hoʻohālikelike me kāna mau analogues. Ua kōkua ka lāʻau lapaʻau a ʻaʻole i hopena i nā hopena ʻaoʻao.

Alexander, 43 makahiki, Volgograd

Inu wau i kēia lāʻau lapaʻau no ka pale ʻana o ka maʻi maʻi. Hoʻomaka ke kōʻai koko, a ʻōlelo ke kauka iā Metformin. ʻAʻole i loaʻa iaʻu kekahi hopena maikaʻi ʻole i ka wā o ka lapaʻau.

Ekaterina, 27 makahiki, Moscow

Ma hope o ka hānau ʻana, hoʻomaka koke wau e ola. ʻAʻole hiki iaʻu ke pili i kaʻai ʻana i nā meaʻai lōʻihi no ka manawa lōʻihi, no laila ua hoʻoholo wau e hoʻāʻo iā Metformin e hōʻemi i ka momona. Ua kōkua ka lāʻau lapaʻau e hōʻemi i ka 5 kg i hoʻokahi mahina. Lūmū maloʻo, ʻaʻole hiki ke hoʻonele nui.

Arina, 33 mau makahiki, Irkutsk

Hoʻomaka wau e lawe i kēia mau pala ma ke kauoha o ke kauka. ʻO ka lāʻau lapaʻau e hōʻemi i ka momona a me nā mea makemake i nā sweets. I loko o ka mahina o ka hoʻopuka ʻana, ua hoʻemi ʻia koʻu koʻikoʻi e 4 kg, aʻu i hauʻoli ai. ʻAʻohe hopena hopena.