ʻAno maʻi type 1

Aia nā kekona beta i loko o ka pancreas e kāpae i ka insulin. Hoʻokomo ka Insulin i ka halihali o ka glucose mai ka plasma koko i nā ʻilio pono e pono ai. ʻO nā ʻōhua kekahi he nui e koi ka nui o ka glucose: nā maka, ka puʻuwai, nā kīʻaha koko, nā ʻōpū, nā ʻōnaehana. ʻO ke kumu o ka maʻi diabetes type 1 ka make keka make o ka pancreatic beta a hoʻopau i ke synthesizing insulin. Nui ka nui o ka glucose i loko o ke koko, ʻaʻole naʻe e hiki i nā lālā pono e pono ai. ʻAʻole lawa nā mea ʻai i ke kō, a hele ma hyperglycemia i ke koko.

Pehea e hōʻike ʻia ai ka maʻi āpau 1

Hoʻomaka pololei ke ʻano maʻi maʻi ʻōpala 1. I ka mea maʻi ua hoʻolaha ʻia ka makewai, ka maloʻo maloʻo, inu ʻono ʻo ia i nā ʻano wai nui a nui hoʻi i ka urinates. Hāʻawi kekahi mau mea maʻi i ka meaʻai a me ka nausea, aʻo nā mea ʻē aʻe, ma ke ʻano ʻē, ʻai nui. Akā, ʻelua wikiwiki e lilo i ka momona - a hiki i 20 kg i kekahi mau pule. Eia kekahi, hopohopo nā poʻe maʻi e pili ana i ka nāwaliwali, haunaele, hoʻemi i ka hana, nā hiamoe ʻole. Ma waho o ka mālama ʻana i nā mea maʻi me ka diabetes type mellitus type, hoʻokomo koke ka ketoacidosis i hiki ke hele i loko o kahi como ketoacidotic.

ʻAno maʻi type 1

ʻO ka lapaʻau no ka maʻi maʻi type 1 he papahana ponoʻī no ka lawelawe ʻana i nā lāʻau lapaʻau e loaʻa ana ka insulin, no ka mea, i nā hihia koʻikoʻi loa, ʻaʻole ʻae ʻia kou insulin ponoʻī.

No laila, ʻo nā 2 mau kumu nui o ka mālama ʻana i ka maʻi mellitus o ka maʻi type 1

  • Diet a me kā kāʻei pono
  • Inine hoʻōla.

I kēia lā, ʻo ka hoʻomakaʻana o ka insulin mai waho o ke ala wale nō e hānai ai i ka maʻi diabetes type 1. Inā ʻōlelo kekahi o nā mea hana lāʻau lapaʻau e hana ana i nā lāʻau i hiki ke mālama i kēia maʻi, he hoʻopunipuni maikaʻi kēia.

Aia he 2 ʻano o nā lāʻau lapaʻau e loaʻa ai ka insulin:

  • insulins pōkole (humalog, actrapid, etc.),
  • insulins long-acting (lantus, protofan, levemir, etc.).

ʻO ka ʻōnaʻi maʻamau o ka insulin e like me kēia:

  • kakahiaka - ka lōʻihi o ka insulin
  • ma mua o ka ʻaina kakahiaka, ʻaina awakea, ʻaina awakea - insulin
  • i ka pō - insulin i mālama i ka hana.

Kēia nā koho o ka insulin e ka endocrinologist. Akā, ʻo ka nui o nā mea hana pōkole hana pōkole e lawelawe ʻia ma mua o ka papa ʻaina e hilinaʻi i kāna nui helu. Ma ke kula kula o ka maʻi maʻi, e aʻo ʻia nā mea maʻi me ka maʻi diabetes e helu i nā wae ʻai ʻai i loko o ka meaʻai a hoʻokele e like me ka nui o ka insulin e like me ka mea e pono ai. I kēlā me kēia lā, pono nā mea āpau me ka maʻi maʻi e nānā i ko lākou kaila glucose koko me kahi mika glucose koko ponoʻī.

ʻO ke ʻano maʻi maʻi type 1 ke ola lōʻihi. Minamina, ua pono ka maʻi i kēia lā.

ʻAno meaʻai maʻiʻai 1

Ma mua o ka hoʻomaka ʻana i ka hoʻomaʻamaʻa, koho i ka metode ʻano, pono e noʻonoʻo i nā kumu o nā maʻi, nā hōʻailona hōʻailona e hōʻike ana iā ia, nā hana diagnostic. ʻO ka maʻi mellitus ka maʻi haki i ka hana o ka pancreas, kekahi mau hana i ke kino o ke kanaka, i hoʻonāukiuki ʻia e ka hapa ʻole o ka insulin. I kahi hihia o nā maʻi, nā maʻi pancreatic e kuleana no ka hana ʻana o ka hormone hiki ʻole ke hoʻokō pono i kā lākou hana. I ka hopena, hoʻonui ʻia nā hōʻailona gula, e pili maikaʻi ana i nā hana o nā ʻōpū, ke olakino.

ʻO ka hemahema o ka insulin a me ka kō nui o ke kō koko e hōʻeha i nā hopena e hiki ʻole ai: ka ʻike maka ʻole, ka hana o ka lolo, ua hoʻokahe ʻia nā kīʻaha koko. I mea e hoʻoponopono ai i ka pae o ka hormone, ke kaʻina metabolic, ʻike ʻia nā mea maʻi me ka type 1 diabetes mellitus e koi i nā inikua i kēlā me kēia lā i ko lākou ola. ʻAʻole hiki ke mālama ʻia ka lāʻau lapaʻau ʻole me ka maʻi type o ka maʻi type 1, ʻokoʻa nō ke ʻano o ka lāʻau o ka hormone.

ʻAʻole ʻike nā ʻepekema i nā kumu kūpono ʻoiaʻiʻo e hoʻonāukiuki i ka hōʻemi o ka insulin hormone. Me kahi kiʻekiʻe o ka hopena hiki ke kānalua i ke kumu nui o ka hoʻomohala ʻana i ka maʻi pākahi type 1 i ka luku ʻia ʻana o nā β-cell e loaʻa ana i ka pancreas. A ʻo nā pono nui no kēia pilikia ka mea i hiki i ke ʻano o nā ʻano:

  • ʻO ka heleʻana o nā gen ka mea e hoʻoholo ai i kahi predisposition huaʻōlelo i ka maʻi maʻi.
  • Malfunctions o ka ʻōnaehana pale, ka papa o nā kaʻina autoimmune.
  • ʻO nā maʻi ma mua o ka maʻi maʻi, ka maʻi maʻamau, no ka laʻana, ka ʻōpala, nā puʻupuʻu, ka hepatitis, ka ʻenehana.
  • ʻO ke koʻikoʻi, kūloko i ka noʻonoʻo noʻonoʻo.

No nā maʻi type 1, loaʻa mau nā hōʻailona, ​​like me ke ʻano lua. ʻAʻole kahi i mākaʻikaʻi ʻia nā hōʻailona a pau, no laila, luhi pinepine ka hopohopo i ka mea maʻi a hiki i ka hoʻomaka ʻana o ka ketoacidosis, i kekahi manawa e alakaʻi ai i nā hoʻopiʻi hou ʻole ʻia o ka maʻi. He mea nui ia e kiaʻi pono i kou olakino a inā i ʻike ʻia kekahi mau hōʻailona o ka maʻi maʻi, pono ʻoe e lawe i ke ʻano o ke koko, ke ʻano urine a kipa aku i kahi kauka i ʻike i kēia maʻi - he endocrinologist. Nā hōʻailona hōʻailona o ka maʻi o ka ʻano mua:

  • He makewai nui mau.
  • Putu maloʻo.
  • Ka hoʻomaʻamaʻa pinepine (i ke ao a me ka pō).
  • ʻO ka makemake ikaika, akā hiki i ka mea maʻi ke hōʻemi i ka paona.
  • ʻO ka hemahema ʻike, lilo nā mea āpau me ka ʻole o kahi kikoʻī.
  • Kaumaha, luhi.
  • ʻO nā manawa maʻamau, ke manawa wikiwiki, nāwaliwali, ka huhū, ka leʻaleʻa i nā tantrums.
  • Hōʻike ka wahine i ka hoʻolālā ʻana o nā maʻi lēpa ma ka wahi o nā mea kikowaena pili ʻole i pane ʻole mai i ka mālama kūloko.

Inā hoʻomaka ka ketoacidosis (nā hoʻopiʻi), ʻike ʻia nā hōʻailona hou aʻe:

  • Hoʻomaopopo maikaʻiʻole, maloʻo.
  • Pili pinepine ka hanu, hohonu.
  • ʻO ka mea ʻala mai ka ʻōpū wahaheʻe, ʻo ia ka mea ʻala o ka acetone.
  • ʻO ka palupalu nui o ke kino, nausea, nalowale ʻike ʻole.

He kauoha kauoha e mālama ai no ka type 1 diabetes mellitus ka hoʻomau mau ʻana i ka inikini insulin. Akā hiki i nā hana hou ke hoʻopale maikaʻi i ka hele ʻana o ka maʻi, hōʻoluʻolu i kona mau hōʻailona a pale i ka hoʻoulu ʻia ʻana o nā haunaele. Hiki ke hoʻopiʻi a hoʻohana i kēia mau ʻano lāʻau ʻē aʻe paha ma hope o ka kūkā ʻana me ke kauka mālama lapaʻau a loaʻa i kāna ʻae ʻia.

ʻO kahi mea nui no ka mālama ʻana i ka maʻi he pono kūpono no ke ʻano maʻi type 1. Ma ke ʻano he puʻuwai kūpono, koho ʻia e kōkua i ka hōʻemi, e pale i ka hoʻonui ʻana i nā kiʻekiʻe o ka glucose, no laila e hiki ke hōʻemi i ka nui o ka insulin. Mea ʻai no T1DM:

  • ʻAʻole pono ka papa ʻōlelo ma ka koina o ke olakino.
  • No ka meaʻai, pono ʻoe e koho i nā ʻano huahana like ʻole.
  • Me ka maʻi diabetes, pono ʻoe e koho i nā huahana kūlohelohe.
  • Hoʻomaopopo ʻia e hoʻokumu i kahi papa no ka hebedoma, me ka nānā pinepine ʻana i nā kīʻaha a me kā lākou mau mea.
  • E nānā i ka hana ʻana i ka meaʻai, nā manawa inikini insulin i ka wā e pale ai i ka pō.
  • Pono ka ʻai ma nā mahele liʻiliʻi, i hoʻokaʻawale ʻia ma kahi o 5 mau manawa i ka lā.
  • E haʻalele i ke kōpaʻa maʻemaʻe mai ka meaʻai, ʻo ia ka mea nui i ka maʻi maʻi me nā maʻi mellitus.
  • Mai ʻai i nā meaʻai mai ka papa inoa "papa ʻia" hoʻi.
  • He mea kūpono ke hāʻawi aku i ka ulaula.

Ka mea ālai ʻia loa ʻole e ʻai:

  • Nā kumuhana a pau - nā ʻano wai like ʻole (nā manamana, nā koloka, nā pōpō).
  • ʻO ka alakino, ʻoi loa, e pilikia i nā hihia i ka papa ʻaina mellitus me ka wai ʻulaʻawa ʻawaʻawa.
  • Nā hua momona (e.g. mango, banana, grape, melon).
  • Kaʻu wai.
  • ʻO nā huahanaʻai wikiwiki.
  • ʻO nā mea momona, ʻohi, nā momona momona.

Kālai meaʻai, papa kuhikuhi:

  • ʻO ka pāʻina nui ka ʻaina kakahiaka. ʻOi aku ka maikaʻi e koho i ka porridge, nā hua, nā greens, tea ʻona.
  • ʻO ka kīʻaha i haʻahaʻa loa nā huaʻaʻai haʻahaʻa a me nā mea ʻai paha.
  • ʻAno iʻa - kākele kuke, nā mea ʻai kuke i ka pā hōlua a i ʻole ka mea kanu ʻana, i kahi ʻāpana i kālua ʻia a iʻa paha.
  • Snack - nā huahana waiū-ʻaha momona momona, ʻaila huaʻai a ʻai ʻole berena me nā kīa ʻole ʻia.
  • Kaʻaina - iʻa ʻai ʻia a kīleʻa paha, mea ʻai - ʻai hou a ʻaū ʻia paha, nā iʻa i ʻaʻa, nā huahana pā me ka haʻahaʻa o nā momona momona.

Hoʻomaʻamaʻa kūlohelohe

ʻO ia kekahi o nā ʻoihana no ka mālama ʻana i ka maʻi diabetes. No ka hana maoli, ʻaʻole e holo pono i ka maʻi, akā kōkua ka hoʻohaʻahaʻa i ke kōpaʻa koko. I nā pilikia maʻamau, hiki i ke kaumaha ke alakaʻi i ka piʻi o ka glucose, no laila ma mua o ka hoʻomaka ʻana i nā papa, pono ʻoe e ʻimi i kauka. I ka wā e aʻo ai i ka maʻi maʻi maʻa, he mea nui e ana i ke kōpaʻa ma mua o ka hoʻomaʻamaʻa ʻana, ma ka waenakonu o ke aʻo a ma ka hopena. Pono ʻoe e nānā mau i ka insulin a no kekahi mau kuhikuhi e ʻoi aku ka maikaʻi o ka hoʻopau ʻana i ka papa hana:

  • 5.5 mmol / L - kahi haʻahaʻa haʻahaʻa ma kahi o ke pāʻani ʻana i hiki ai ke palekana. Hoʻomaopopo ʻia e ʻai ʻoe i kahi huahana kalapona kiʻekiʻe (e like me ka berena) ma mua o ka hoʻomaka ʻana i kāu hana.
  • Nā ʻōkuhi ma ka pae 5.5–13.5 mmol / L hāʻawi i ke kukui ʻōmaʻomaʻo no ka hoʻomaʻamaʻa.
  • Hōʻike i nā ʻōkuhi ma luna o ka 13.8 mmol / L ka laʻa o ka hoʻōho o ke kino pilikino, hiki ke lawelawe i kēia no ka impetus no ka hoʻomohala ʻana i ka ketoacidosis, a ma 16,7 mmol / L - ke pāpā ʻia ʻole ʻia.
  • Inā hoʻomaʻamaʻa ka kō i ke kō i ka 3.8 mmol / L a i ʻole a emi aʻe, kāpae i ka hoʻomaʻamaʻa koke.

Hana i nā hoʻomaʻamaʻa kino no nā poʻe maʻi me ka maʻi diabetes type 1 nona nā hiʻohiʻona:

  • Pono e paʻa ʻia nā papa i ka lewa hou e loaʻa ai ka hopena kiʻekiʻe.
  • ʻO ka maʻamau maʻamau a me ka lōʻihi o nā papa no ka maʻi type 1 ka hapalua hola, he kanahā mau minuke, ʻelima manawa i kahi hebedoma a 1 mau hola me nā papa o kēlā me kēia lā.
  • Ke hele nei i ka workout, pono ka ʻai ʻana i kekahi mau meaʻai no kahi mea ʻai e pale ai ka hypoglycemia.
  • I nā papa mua, koho i nā hana maʻalahi, i ka manawa o ka wā, e hoʻohui malie i ka hoʻonui ʻana iā lākou, e hoʻonui ana i ka kaumaha.
  • E hoʻomaʻamaʻa loa i nā hoʻomaʻamaʻa: jogging, totō, squats, body turn, aerobics intensive, hoʻoikaika kino.

ʻO nā mea maʻi no ka maʻi maʻi

ʻO nā kapoma diabetes DiabeNot he lāʻau lapaʻau maikaʻi e hoʻomohala ʻia e nā ʻenekema Kelemania mai Labor von Dr. Budberg ma Hamburg. Ua hana mua ʻo DiabeNot ma ʻEulopa ma waena o nā lāʻau lapaʻau maʻi.

Fobrinol - hōʻemi i ke kō koko, hoʻoneʻe i ka pancreas, hoʻemi i ke kaumaha o ke kino a hoʻomaʻamaʻa i ke koko. No ka palena palena ʻole!

  • ʻO ka insulin hana pōkole. Hoʻonui ka lāʻau i ka ʻumikumamālima mau minuke ma hope o ka hoʻoʻau ʻia ʻana.
  • Hoʻohana ʻia ka lāʻau lapaʻau hana 2 mau hola ma hope o ka hoʻokele ʻana.
  • Hoʻomaka ka hana lōʻihi o ka insulin e hana ʻehā, ʻeono mau hola ma hope o ka loaʻa ʻana o ka maʻi.

Hiki iā keʻae i ka insulin i loko o ke kino o nā mea maʻi me ka maʻi ʻano type 1 ma ka maʻi ʻana, ka hoʻohana ʻana i kahi syringe kūikawā me kahi paʻu nāhele a i ʻole ka pala.

ʻO ka hui ʻelua o nā lāʻau lapaʻau nā ʻano penei:

  • ACE (angiotensin-e hoʻohuli ai i ka enzyme inhibitor) - kahi lāʻau lapaʻau e kōkua ana e hoʻomaʻamaʻa i ke koko, e pale ana a hoʻoheheʻe paha i ka hoʻomohala ʻana o ka maʻi ʻeha.
  • ʻO nā lāʻau lapaʻau e hakakā i nā pilikia o ka pēpē gastrointestinal i kū me ke ʻano maʻi type 1. Ke koho nei ka koho o ka lāʻau lapaʻau ma ka pathology frology a me ke ʻano o ka pilikia. Hiki iā ia ke Erythromycin a Cerucal paha.
  • Inā he manaʻo ma ka naʻau a i ʻole ka maʻi maʻi vaskular, ʻoi ʻia e lawe iā Aspirin a i Cardiomagnyl.
  • I ka hanana o ka neuropathy peripheral, hoʻohana ʻia nā lāʻau lapaʻau me kahi hopena anesthetic.
  • Inā he pilikia ka potency, e kūkulu ana, hiki iā ʻoe ke hoʻohana iā Viagra, Cialis.
  • ʻO Simvastatin a i Lovastatin e kōkua i ka hoʻohaʻahaʻa haʻahaʻa.

ʻO nā hopena palekana

Nui nā poʻe maʻi me ka type 1 diabetes mellitus e hoʻohana i nā ala kuʻuna e pale i ka maʻi. ʻO kekahi mau meaʻai, nā mea kanu, nā uku e hiki ke hoʻemi i ka nui o ke kō koko koko a hoʻomaʻamaʻa ʻia paha ia. ʻO nā mea lapaʻau kaulana no nā laʻana, ʻo ka lāʻau lapaʻau ka:

  • Beans (5-7 mau ʻāpana) ninini i ka 100 ml o ka wai ma ka mahana o ke keʻena i ka pō nui. Ma kahi ʻōpū ʻole, ʻai i nā pīniʻai a inu i ka wai. Pono e kali i ka ʻaina kakahiaka no hoʻokahi hola.
  • E hana i kahi infusion e loaʻa ka 0.2 lita o ka wai a me 100 gr o nā huaʻa oat. I ka hoʻohana ʻana ʻekolu mau manawa i kahi lā he dosis 0.5 kīʻaha.
  • E hoʻopiha i kahi thermos no ka pō me ka hui pū o 1 kīʻaha wai (wai wai) a me 1 tbsp. l ʻāʻā. E hōʻalo i ke kakahiaka a inu i ka 1/3 kīʻaha ma kēlā me nā lā he ʻumikumamālima.
  • E kāwili i kekahi mau kākahu lauwā a ke ʻokeʻo a hiki i ka hoʻomohala ʻana, hoʻohui i ka wai (0,5 lita) a hoʻopaʻa i ka hapalua hola i kahi wahi mahana. No ka mai wai, e inu me ka wai i ka lā a pau.
  • No 7 mau minuke, kuke i ka 30 mau kālena o ka ivy, e hoʻolapalapa ʻia me ka 0.5 l o ka wai, koi i nā hola he nui, ka lepo. Nā kānāwai komo: inu ma mua o ka papa kai nui.
  • E hōʻiliʻili i nā ʻāpana he kanaha walnuts, hoʻohui iā 0.2 l o ka wai maʻemaʻe a hoʻōki i hoʻokahi hola i loko o ka ʻauʻau wai. E hōʻalo a inu i ka tincture ma mua o ka ʻai i ka puna.

Hoʻopau hou

Ke hana nei ka hana o ka noi ʻana i ka maʻi mellitus o ka maʻi mellitus a me nā ʻano o kāna mālama ʻana i nā makahiki he mau makahiki i loko o nā ʻāina ʻē aʻe o ka honua. Aia kekahi papa o ka ʻepekema ʻo kāna kumu waiwai nui e hoʻonā i kēia pilikia. Hoʻopili ʻia kā lākou noiʻi e nā ʻoihana lāʻau lapaʻau, nā ʻoihana nui, nā hana manawaleʻa, nā kumu, a me ke aupuni. Nui nā hana hoʻohiki i ka hoʻomohala e pili ana i ka maʻi type 1:

  • Ke hoʻāʻo nei nā kānaka ʻepekema e hana i nā ʻōhua olakino i nā kānaka o ke kikowaena beta, hiki iā lākou ke hana i ka hana o ka hoʻoulu ʻana i ka hormone a hoʻōla i ka maʻi diabetes. Akā no ka loiloi loiloi a me ka hiki ke hoʻohana i ka hāmeʻa e mālama ai i nā poʻe me ka maʻi maʻi, ua mamao loa ia.
  • Ke hana nei kekahi mau mea noiʻi e pili ana i kahi huakaʻi e pale ai i ka hoʻomohala ʻana i kahi kaʻao autoimmune e hele ai nā maʻi beta pancreatic, a ulu ka maʻi mellitus.

Ua aʻo ʻia nā poʻe i loaʻa me ka maʻi type 1 ka noho me ia, e noho nei me ka pono mau no ka inikini insulin, hoʻololi i ko lākou mau ʻano a me nā makemake. Ke alakaʻi nei ka poʻe maʻi maʻi type 1 i ke ola piha, leʻaleʻa a mahalo i nā manawa āpau, me ka lana o nā ʻepekema e huli ana i kekahi lā i ka "magic pill" mai kā lākou pōʻino. Inā ua pilikia ʻoe i ka pilikia o ka maʻi diabetes mellitus, ʻike i nā ala hou o ka lāʻau lapaʻau a i ʻole a mākaukau paha e kaʻana i kou manaʻo - waiho i kahi ʻōlelo.

Nā hiʻohiʻona o waho

Uaʻike nui nā mea kūlohelohe i ka etiology o ke ʻano maʻi i ka maʻi 1.

ʻEwili pū ʻia nā māhoe like me nā genotypes like i ka maʻi maʻi i ka manawa like i loko o 30-50% o nā hihia wale nō.

ʻO ka laha o ka maʻi i waena o ka poʻe no ka lāhui Caucasian ma nā ʻāina ʻē aʻe ʻokoʻa ka ʻumi. Ua mālama ʻia aia i loko o ka poʻe i neʻe mai loko mai o nā wahi me ka liʻiliʻi haʻahaʻa o ka maʻi maʻi ma nā wahi me ka nui o ke ola poʻokela, ʻoi aku ka nui o ka maʻi diabetes type 1 ma mua o ka poʻe i noho i ko lākou ʻāina hānau.

Nā lāʻau lapaʻau a me nā lāʻau ʻē aʻe Hoʻoponopono

ʻO Streptozocin, i hoʻohana mua ʻia me ka meaʻawaʻawa, i kēia manawa e hoʻohana ai i ka mālama ʻana i ke kano pancreatic metastatic, he mea momona loa i nā pili beta pancreatic i hoʻohana ʻia e hōʻino i kēia mau ʻāpana i nā hoʻokolohua holoholona.

ʻO ka makekona o ka honu Pyrinuron (Pyriminil, Vacor), i hoʻohana ʻia ma ʻAmelika Hui Pū ʻIa i ka makahiki 1976-1979, e hoʻomohala mau ʻia ma kekahi mau ʻāina, i nā sellyly hōʻino nā cell beta pancreatic.

Hoʻokumu ka hana pathogenetic i ka hoʻomohalaʻana o ke ʻano type type 1 i ka nele o ka hoʻokumu ʻana o ka insulin e nā cell endocrine (β-cells of the pancreatic Islets of Langerhans). ʻO nā ʻano maʻi diabetes like 1 no ka 5-10% o nā maʻi āpau o ka maʻi maʻi, e ulu pinepine ana i ka wā kamaliʻi a me ka wā ʻōpio. Hōʻike ʻia kēia ʻano maʻi maʻi i ka mua o nā hōʻike o nā hōʻailona, ​​ka holomua i ka wā lōʻihi.ʻO ke kāhea wale nō ke kūlohelohe o nā inikini insulin o ke ola e hoʻomaʻamaʻa ai i nā hana a ka mea maʻi. Ke hana hou ʻana, ka helehelena kīpoki 1 ka neʻe nui a alakaʻi i nā hoʻopiʻi koʻikoʻi e like me ka maʻi cardiopopati maʻi, ka hōʻeha, ka pōpoki o ka maʻi, ka retinopathy diabetes, nā ʻōpū maʻi maʻi maʻi, ketoacidosis a me ka maʻi maʻi maʻi, ka mea e alakaʻi ai i ka maʻi a make paha o ka mea maʻi.

ʻO ka paʻi 1999 o ka World Health Organization's Definition, Diagnosis, a me ka Haka o ka maʻi Diabetes a me kāna mau hoʻonā e hāʻawi i kēia mau papaʻōlelo i lalo nei:

ʻAno maʻi maʻi Nā maʻi maʻi
ʻAno maʻi type 1ʻO ka luku ʻia ʻana o ka pancreatic β-cell, ka mea maʻamau e alakaʻi i ka hoʻopauʻana i ka insulin.
Autoimmune
Idiopathic
ʻAno maʻi type 2Me ka pale kūlike o ka insulin a me ka nele o ka insulin i ʻole a i ʻole ka nui o ka pale i ka huna ʻana i ka insulin me ka ʻole ʻole o ka pale ʻana i ka insulin.
ʻO ka maʻi maʻi gestationalHele i ka wā hāpai.
ʻO nā ʻano maʻi ʻē aʻe
Nā hemahema genetic i ka hana β-cellMODy-1, ʻYLI-2, MODY-3, ʻYLI-4, ka mutation DNA mitochondrial, ʻē aʻe.
Nā hemahema genetic i ka hana o ka insulinKomo i kahi kū'ē o ka insulin, leprechaunism, Rabson-Mendenhall syndrome, lipoatrophic diabetes, ʻokoʻa.
ʻO nā maʻi o ka pancreas exocrineʻO ka pancreatitis, trauma / pancreatectomy, neoplasia, fibrosis cystic, hemochromatosis, pancreatopathy fibrocalculeous.
EndocrinopathiesʻO Acromegaly, ʻehaʻeha o Cush, glucagonoma, pheochromocytoma, thyrotoxicosis, somatostatinoma, aldosteroma, ʻokoʻa.
ʻO ka lāʻau lapaʻau a i ʻole ka DiabetesVacor, thiazides, pentamidine, dilantin, nicotinic acid, α-interferon, glucocorticoids, β-blockers, thyroid hormone, diazoxide, ʻokoʻa.
Nā maʻi maʻi maʻiCytamegalovirus, rubella, virus influenza, hepatitis B maʻi a me C, opisthorchiasis, echinococcosis, clonchorrosis, cryptosporodiosis, giardiasis
ʻO nā ʻano maʻamau ʻole o ka maʻi maʻamau-mediated"Stiff-man" - ʻeha (immobility syndrome), ke kūlana o nā antibodies i nā ʻĀina insulin, ke ʻano o nā antibodies i nā insulin.
Nā hui genetic e pili ana i ka maʻi diabetesDown syndrome, Lawrence-Moon-Beadle syndrome, Klinefelter syndrome, myotonic dystrophy, Turner syndrome, porphyria, Wolfram syndrome, Prader-Willi syndrome, Friedreich ataxia, Huntington's chorea, me nā mea'ē aʻe.

Hoʻoulu ka hemahema o ka insulin i ke kino ma muli o ka lawa ʻole o ka huna ʻana o nā β-cell i nā mokupuni o ka pancreatic o Langerhans.

Ma muli o ka nele o ka insulin, ua hoʻoneʻe ʻia nā kōmole e pili ana i ka insulin (ate, ka momona a me ka uaua) i ka hiki ke komo i ka glucose o ke koko a, ma muli o kēia, ke piʻi aʻe ka pae o glucose i ke koko (hyperglycemia) - he hōʻailona o ka maʻi kāpena o ka maʻi maʻi. Ma muli o ka nele o ka insulin, e hoʻowalewale ʻia ka momona hōʻalo i ka kiko o ka adipose, ke alakaʻi nei i ka hoʻonui i ko lākou pae i ke koko, a me ka hōʻemi ʻana i ka hoʻōho o ka protein i ka ʻōpū o ka iwi, e hoʻoulu ʻia i ka nui o ka kō o nā waikawa amino i ke koko. Hoʻololi ʻia nā haʻalulu o nā catatsism o nā momona a me nā protein e ka ʻalopona i loko o nā kino ketone, ka mea i hoʻohana ʻia e nā kinekona pono ʻole o ka insulin (ma ka nui o ka lolo) e mālama i ka pale o ka ikehu e pili ana i ke kua o ka nele o ka insulin.

ʻO Glucosuria kahi hana kūpono e hoʻoneʻe ai i ke kaʻe koko nui mai ke koko inā he kiʻekiʻe ka glucose i ka nui o ka paepae no ke keiki (ma ka 10 mmol / l). ʻO ka Glucose kahi mea hoʻomehana osmologically a me ka hoʻonui ʻana i kona kao i loko o ka urine e hoʻoulu i ka hoʻonui ʻana o ka wai (polyuria) e hiki ke alakaʻi i ka dehydration inā ʻaʻole ka luina o ka wai i ka wai o ka nui o ka nui o ka kō (polydipsia). Me ka nui o ka pohō ʻana o ka wai i loko o ka pāʻai, paʻī ka paʻakai mineral - ka nele o nā cation o ka sodium, potassium, calcium, a me ka magnesium, anions o chlorine, phosphate a me ka bicarbonate ulu.

Aia he 6 mau hoʻolālā o ka hoʻomohala ʻana i ka maʻi mellitus o ka ʻano mua (e hilinaʻi i ka insulin):

  1. ʻO kahi predisposition genetic i ka maʻi maʻi e pili ana me ka pūnaehana HLA.
  2. Hoʻomaka kaulike hypyphetical. Hana ʻino i nā β-cell e nā ʻano like ʻole o ka maʻi maʻi a me ka hana ʻana i nā hana kūlohelohe. Loaʻa i nā mea maʻi nā antibodies i nā selela i loko o kahi titel liʻiliʻi, akā ʻaʻole naʻe i loaʻa ka huna ʻia o ka insulin.
  3. ʻO ka insulin autoimmune ʻano. He kiʻekiʻe ka titio antibody, ua emi ka nui o nā β-cells, a emi ka hiʻona o ka insulin.
  4. Hōʻemi ka hoʻemi ʻia o ka glucose i hoʻonui ʻia e ka lewa. I loko o nā kūlana koʻikoʻi, hiki i ka mea maʻi ke ʻike i kahi kaanilelika o ka hoʻoliʻihāʻana i nā glucose hou (NTG) a me ka wikiwiki o ka glucose plasma glucose (NGF).
  5. Hōʻikeʻike Clinical i ka maʻi diabetes, me kahi hanana paha o ka "honeymoon". Ua hoʻemi nui ʻia ka huna huna ʻana i ka ʻōpū, ʻoi aku ka nui o nā 90% o nā make β-cell.
  6. Hoʻopiha piha loa o nā pū β, hoʻopau piha i ka huna ʻana o ka insulin.

Hoʻolima ʻia nā hōʻike maʻi o ka maʻi ʻaʻole wale nō e ke ʻano o ka maʻi mellitus, akā ma ke ʻano o kona papa, ʻo ka nui o ka uku no ka hoʻohaʻawaʻe kalepa, ka hele ʻana o nā hoʻopiʻi vascular a me nā maʻi ʻē aʻe. ʻO ka ʻokoʻa, hoʻokaʻawale ʻia nā ʻōmaʻomaʻo i nā hui ʻelua:

  1. hōʻailona e hōʻike ana i ka hoʻēmi ʻana o ka maʻi,
  2. nā hōʻailona e pili ana i ka hele ʻana a me ka paʻakikī o ka angiopathies maʻi, nā neuropathies, a me nā mea hou e hoʻopiʻi ana a paʻa paha.

  • ʻO ka Hyperglycemia ke kumu o ka nānāʻana o ka glucosuria. ʻO nā hōʻailona o ke kō koko nui (hyperglycemia): polyuria, polydipsia, hōʻemi nui me ka momona nui, ka waha maloʻo, nāwaliwali
  • ka microangiopathies (diabetes retinopathy, neuropathy, nephropathy),
  • macroangiopathies (atherosclerosis o ka lāʻau coronary, aorta, nā moku GM, nā pae haʻahaʻa), maʻi syndrome wāwae
  • nā kikowaena concomitant: furunculosis, colpitis, vaginitis, urinary tract infection a pēlā aku.

Ma ka hana lapaʻau, ʻike pono ʻo ia no ka maʻi maʻi o ka maʻi maʻamau o ke ʻano o nā hōʻailona maʻamau o ka maʻi hyperglycemia (polyuria a me polydipsia) a me ka hyperglycemia i hoʻopaʻa ʻia e ke kāpili - glucose i loko o ke plasma o ke koko capillary ≥ 7.0 mmol / l (126 mg / dl) ma kahi ʻōpū ʻole a / a ≥ 11.1 mmol / l (200 mg / dl) 2 mau hola ma hope o ka hoʻāʻo ʻana i ka glucose. HbA1c pae> 6.5%. Ke hoʻokumu ʻia nei kahi maʻi, hana ka lāʻau kauka e like me kēia algorithm.

  1. Hoʻololi i nā maʻi i hōʻike ʻia e nā ʻano like like (make wai, polyuria, hōʻemi kaumaha): diabetes insipidus, psychogenic polydipsia, hyperparathyroidism, kidney renal failed, a pēlā aku ua pau kēia hana me kahi hōʻike o ka laboratopa o ka maʻi hyperglycemia syndrome.
  2. Kuhi ʻia ka ʻano ʻōloli o ka maʻi maʻi. ʻO ka mea mua, ua ʻoka ʻia nā maʻi i hui ʻia ma nā pūʻulu "ʻAi i nā ʻano maʻi ʻē aʻe". A laila ua hoʻopau ʻia ka pilikia o ka maʻi type 1 a i ʻole ke ʻano type type 2. ʻO ka hoʻoholo ʻana o ka pae o C-peptide ma kahi ʻōpū ʻole a ma hope o ka hoʻokō ʻia. Ke hoʻohana nei i nā kaʻina like, kahi kuhi o ka ʻike o nā antibodies o GAD i ke koko.

  • Ketoacidosis, hyperosmolar coma
  • ʻO ka comy hypoglycemic (ma ka hihia o ka nui o ka insulin)
  • Nā micro diabetic - a me ka macroangiopathy - paneʻe vascular āpau, hoʻonui i ka palupalu, hoʻonui i ka makemake i ka trombosis, i ka hoʻomohala ʻana o ka varo atherosclerosis,
  • Polyneuropathy Diabetic - peripheral nerve polyneuritis, ʻeha ma ke ake o nā wahi iwi o ka nerve, paresis a paralysis,
  • Nā lāʻau kanalohi maʻi - hōʻeha i ka ʻōpū, "crunching", palena o ka hoʻoweliweli, hōʻemi i ka nui o ka wai o ka synovial e hoʻonui i ka tetala,
  • Ophthalmopathy Diabetic - ulu mua o nā cataracts (ke ao ʻana o ka lens), retinopathy (lesi retinal),
  • ʻO ka nephropathy Diabetic - hoʻopōʻino i nā pēpē me ka puka o ka protein a me nā koko koko i loko o ka pāʻai, a me nā hihia koʻikoʻi me ke kūkuluʻana i kahi glomerulonephritis a me ka hana ʻole o ka renal,
  • Encephalopathy Diabetic - nā loli i ka psyche a me ke ʻano, ka hana a me ke kaumaha paha, nā hōʻailona o ka hoʻowalewale ʻōnaehana o ka hanana.

Nā kuʻuna aʻoaʻo nui

ʻO nā pahuhopu nui o ka mālama:

  • Hoʻopau i nā hōʻailona āpau o ka maʻi maʻi
  • Loaʻa i ka mana metabolic maikaʻi ma luna o ka manawa.
  • ʻO ka paleʻana i nā hoʻopiʻi a me nā hopena paʻakikī o ka maʻi maʻi
  • E hōʻoiaʻiʻo i ka kiʻekiʻe o ke ola no nā maʻi.

E hoʻokō i kēia mau pahuhopu:

  • mea ʻai
  • kahi hana kino pilikino (DIF)
  • ke aʻo ʻana i nā maʻi maʻi kūʻokoʻa a me nā hana maʻalahi o ka mālama ʻana (ka mālama ʻana i ko lākou maʻi)
  • ke hoʻopaʻi kūʻokoʻa

ʻO ka Insulin Therapy Hoʻoponopono

Hoʻokomo ka mālamaʻana i ka insulin i ka uku kiʻekiʻe loa no nā pilikia o ka pakanā o ke kinipōpō, ka pale ʻana i ka hyperglycemia a me ka pale ʻana i nā koi o ka maʻi maʻi. He mea nui ke alakaʻi o ka insulin no ka poʻe me ka maʻi type type 1 a hiki ke hoʻohana ʻia i kekahi mau kūlana no ka poʻe me ka maʻi diabetes type 2. Hoʻokahi ala e lawelawe ai i ka insulin i ka poʻe me ka maʻi type type 1 a me ka type 2 ma o ka pā konohiki.

Hoʻololi Pilot

ʻO ka hana mua o nā lāʻau lapaʻau mua o ka huehue DNA BHT-3021 i hele e ka poʻe maʻi 80 ma mua o 18 mau makahiki i ka maʻi i hōʻike ʻia me ka maʻi type o 1 i nā makahiki 5 i hala. ʻO ka hapalua o lākou i loaʻa i nā inikini intramuscular o BHT-3021 i hoʻokahi pule no 12 mau pule, a ua loaʻa i ka hapa ʻelua ka placebo. Ma hope o kēia manawa, hōʻike ka pūʻulu e loaʻa ana i ka maʻi kanalima i ka nui o ka C-peptides i ke koko - he mau biomarker e hōʻike ana i ka hoʻihoʻi hou o nā hana beta-cell.

ʻO ka hoʻohanaʻana i kahi meaʻai ketogenic e hiki ai iā ʻoe ke hoʻokō i ka hoʻomehana glucose maikaʻi, e hōʻemi i nā hopena i nā pilikia.

ʻO nā kālā e hoʻomaikaʻi i ka hana o ka enzymatic o ka pancreas. Hoʻoponopono

No ka pilina me ka hana ʻino pancreatic: ka hakakā ʻana me ka hypoxia (oxygenation oxygenation, cytochrome, actovegin) aprotinin, creon, festal, immunomodulatory therapy (ma mua o kahi maʻi infectious, viral) i ka maʻi maʻi maʻi, a no nā hoʻopiʻi i pili i nā maʻi: ka hoʻoponopono kūpono / lawe ʻana (pancreatitis, echinococcal cyst, opisthorchiasis, candidiasis, cryptosporodiosis) i ka wehe ʻana i ka manawa kūpono o kona foci.

I ka hoʻōla a me ka rheumatic etiology Hoʻoponopono

Detoxorporeal detoxification (hemodialysis). ʻO ka nānā ʻana i ka manawa a me ka hoʻohemo / hoʻoponopono ʻana i ke kumu o ke kumu (d-penicylamine for SLE, desferal for hemochromatosis), ʻo ka hoʻopau ʻia o ka corticosteroids, thiazides, etc., i mālama ʻia ma ke ʻano he hoʻomakeʻe i ka hōʻike ʻana o ka maʻi, kā lākou make ʻana e hoʻohana ana i ka lāʻau antidote kikoʻī)

Hoʻohui hou

ʻO nā mea noiʻi ma ke Kulanui o Kaleponi, San Francisco, ʻo ia ka mea mua i hoʻohuli i nā ʻōpū mau ke kanaka i loko o nā selika hoʻonaninani (insulin cells), kahi nui i koʻo i ka hoʻomohala ʻana i kahi lāʻau no ka maʻi type o ka maʻi (T1).

Ke hoʻololi nei i kēia mau sela, i luku ʻia i nā poʻe maʻi me ka maʻi T1 maʻi, ua lōʻihi ka moemoeā o ka lāʻau lapaʻau regenerative. ʻAʻole hiki i nā kānaka ʻepekema ke hoʻomaopopo pehea e ulu ai nā pū beta i nā kūlana o ka ʻoihana ke hana lākou i ke ʻano like me ka poʻe olakino.

ʻO ke kī i ka loaʻa ʻana o nā selela beta o ke ʻano kahi o kā lākou kūkulu ʻana i nā mokupuni o Langerhans i kahi kanaka olakino.

Ua hiki i nā kānakaʻepekema ke hōʻiliʻili i kēia kaʻina hana i ka ʻoihana. Ua hoʻokaʻawale lākou iā lākou iho i nā ʻāpana pihi pancreatic i hoʻololi ʻia iā lākou i loko o nā ʻōpala islet. A laila ua wikiwiki koke ka hoʻomohala ʻana o nā pū. Hoʻomaka ikaika nā mea maʻi Beta i ke kō koko koko ma mua o nā ʻōhua a ka hua ʻana i ka insulin. Eia nō hoʻi, hoʻomaka ka "puni" o ka mokupuni, me ka liʻiliʻi o nā puke alpha a me nā delta, i hoʻomohala ʻia e like me ka mea i hana ʻole ʻia ma lalo o nā kūlana olakino.

Waiho I Kou ManaʻO HoʻOpuka