Amaryl no ka maʻi maʻi > Nā lāʻau lapaʻau

I ke kaua kūʻē i ka maʻi maʻi kū kūʻa i ka hopena maikaʻi o ka lāʻau ʻAmelika Amaril. ʻO kāna kumu nui, ʻo ia ka hoʻemi ʻana i ke kōpaʻa koko i hiki ke ʻike i nā waiwai. Kuhi aku nā kauka iā Amaril i nā poʻe maʻi i hōʻike ʻia me ka maʻi diabetes mellitus type 2 e hoʻohana ana i ka hoʻokolokolo diagnostic. No ka hoʻokō ʻana i ke koʻikoʻi kiʻekiʻe mai ka mālama ʻana, pono ʻoe e lawe i ka lāʻau lapaʻau, mālama pono ʻia i nā dosis i kuhikuhi ʻia e ke kauka a ʻaʻole lōʻihi ma mua o ka manawa i ʻōlelo ʻia. A i ʻole, ua hoʻoweliweli ʻia ka mea maʻi me nā hopena ʻaoʻao a me ka hoʻopiʻi ʻana o ke ala o ka maʻi.

IMIPO KAHIKO! Hiki ke ho'ōla ma ka maʻi diabetes loa ma ka home, me ka ʻole o nā keʻena a me nā haukapila. E heluhelu wale i ka mea a Marina Vladimirovna i ʻōlelo ai. heluhelu i ka loiloi.

Nā hōʻailona a me nā contraindications

Ua loaʻa i nā papa ʻaina Amaryl kā lākou noi ma ka mālama ʻana i hoʻokahi maʻi wale nō - type II diabetes mellitus a i ʻole ka mea i kapa ʻia ʻole-insulin-depend-diabetes. ʻAʻole hiki ke mālama ʻia kēia ʻano maʻi maʻi i ka insulin, no laila ua hana ʻia ka lāʻau lapaʻau pū ʻia ʻo Amaril M. ʻAʻole ia e ʻōlelo i ka hoʻohana ʻana i kahi lāʻau hoʻokaʻina o ke kō no ka poʻe me ka hoʻomau ʻana i kēlā me kēia mea, a me nā mea i loaʻa i ke ala i nā maʻi a me nā palaleka, nā hemahema lactase a me ka malabsorption (maikaʻi ʻole o ka hoʻopihapiha) o ka glucose - galactose. Ua hoʻohālikelike ʻia ka ʻAmaryl i ka maʻi mellitus type 1 a me kona hoʻopiʻi - ketoacidosis maʻi maʻi (ka nui o nā kino ketone i loko o ke koko). ʻAʻohe mea lapaʻau i kuhikuhi ʻia no ka mālama ʻana i ka maʻi maʻi i nā wahine i kahi kūlana, nā kahu hānai a me nā mea maʻi iki.

Pehea e hoʻohana ai a me ka helu?

Manaʻo ʻia e lawe iā Amaril no ka maʻi maʻi ma hope o ka kūkākūkā ʻana me ke kauka lapaʻau kūpono nona, ma ke kumu o ke kahe ana o ke koko glucose, e kuhikuhi i ka hanana palekana a me ka hopena o ka hopena therapeutic. Hoʻohana ʻia ʻo "Amaryl" e mālama i ka diabetes mellitus type 2 ma ka monotherapy a me ka manawa like me nā lāʻau lapaʻau ʻē aʻe. ʻO ka maʻamau, hoʻomaka ka papa me nā dosis liʻiliʻi, e hoʻonui mālie iā lākou i ka maʻamau o kēlā me kēia lā - 4 mg. I nā hihia koʻikoʻi, hiki ke hoʻonui ʻia ka dosage i 8 mg i kēlā me kēia lā.

ʻO ka hoʻoponopono ʻana i ka hapa o ka lāʻau lapaʻau wale nō ma hope o ke ana ʻana i ka honi koko.

I ka wā o ka mālamaʻana i ka maʻi maʻi, pono e hoʻomanawanui ka mea maʻi i ka glucose i loko o ke koko, no laila e hoʻonui nui ʻia ʻo ia, e hoʻoponopono koke ʻia ka hewa o Amaril. E lawe i nā pā i ke kakahiaka ma mua o ka ʻai mua a i ʻole pololei ma ka manawa o ka ʻaina. Mai kuke i ka dragee, ʻelekele a piha iā ia, a inu mau i ka hapa o ka wai o ka wai.

Nā hopena hopena

I ka hoʻohana ʻana i nā papa Amaril, hiki mai nā hanana ʻino e pili ana.

ka hoʻemi ʻana i ke kō, nā kōpaʻa keʻokeʻo, granulocytes, platelets i ke koko,
haki
luku ʻana o nā ʻōpū koko ʻulaʻula a i ʻole ko lākou hōʻemi i ke kahe koko,
nā hemahema o nā ʻano āpau i ke koko,
ʻeha a ʻeha ʻole i ka ʻōpū,
nā hopena kūlohelohe
paulinapaola
i ka ulu ʻana o nā ate enzyme,
ka hana paʻa ʻaʻe.

Hoʻi i ka papa o nā kikoʻī

Na mea Hanohano

Inā ʻaʻole hiki ke hoʻohana pono i ka hoʻomākaukau ʻana o ka lāʻau lapaʻau Amaril no ka mālamaʻana i ka maʻi maʻi, kau ka poʻe kauka i nā lāʻau lapaʻau e like me ka mea ikaika a me ka hui pharmacological. No laila, hiki i kekahi o nā kikoʻōlelo o kēia ke kahakaha i ke kau ʻana i ke kō.

Aia he mau hoʻohālikelike o Amaril, hoʻokahi o Glemaz.

Nā ʻōlelo kikoʻī

Ke lawe ʻana i "Amaryl" e hoʻoponopono i nā pae koko koko, pono ia e nānā pono i ka pae o ka glucose, ka hana ʻana o nā pūpū a me nā ʻōpio, a nānā pū kekahi i ka mea hoʻoliʻina o ke koko i mea e pale ai i ka hōʻemi o ka nui o nā platelets, hemoglobin a me nā wahi koko ʻula. He mea kūpono ʻole e emi ka hopena o ka lāʻau inā ʻike ka mea maʻi i nā manawa koʻikoʻi a paʻakikī a loaʻa kēia i ka hoʻokuʻu ʻia o ka nui o ka adrenaline i loko o ke kahe koko.

Hiki ke hoʻoikaika a hoʻonāwaliwali i ka hana a Amaril, inā hoʻohana ʻia i nā lāʻau lapaʻau ʻē aʻe. No laila, pono e hōʻike i ke kauka hele e pili ana i nā lāʻau lapaʻau i lawe ʻia a hōʻemi ke kauka i ka nui o nā mea nui a i ʻole ke koho i nā lāʻau lapaʻau ʻē aʻe e launa pū me Amaril. I ka wā o ka mālama ʻana i ka maʻi maʻi, pono e hoʻopau loa i ka waiʻona, ʻoiai ka huaʻai ethyl alkohol i loko o kāna mea e hoʻohiolo ai i ka hopena o ka lāʻau hypoglycemic. Pono e mālama i nā pale ma kahi anu, e pale ʻia mai ka mālamalama a hiki ʻole i nā keiki liʻiliʻi. I mea no ke kolohe ko Amaril e like me ka mea e like me ka mea no ka mellitus maʻi diabetes, pono ʻoe e pili i ka mālama ʻana i nā lāʻau lapaʻau, alakaʻi i kahi ʻano ola a hahai i nā ʻōlelo a pau a kāu kauka.

Manaʻo wale paha i ke ʻano o ka maʻi maʻi?

ʻO ka hoʻoholo ʻana e ka heluhelu ʻana i kēia mau laina i kēia manawa, ʻo ka lanakila ʻana i ka hakakā ʻana me ke kō koko kiʻekiʻe ʻaʻole ma kou ʻaoʻao.

A ua noʻonoʻo paha ʻoe e pili ana i ka mālama ʻana i ka haukapila? Ua hoʻomaopopo ʻia ia, no ka mea, he maʻi pōpilikia nui ka maʻi, ka mea, inā ʻaʻole i hoʻomaʻamaʻa ʻia, hiki ke hopena i ka make. Ka makewai mau, ka wikiwiki wikiwiki, ka ʻike aniani. Ma mua o kēia ʻike kēia mau maʻi āpau.

Akā hiki paha i ka mālama i ke kumu ma mua o ka hopena? Manaʻo mākou e heluhelu i kahi ʻolelo e pili ana i ka hoʻomehana maʻi o nā maʻi. Heluhelu i ka ʻatikala >>

Lapaʻau lāʻau

Kōkua ʻo Glimepiride i ka hoʻemi ʻana o ka glucose koko (ma muli o ka hoʻoulu ʻana o ka insulin e hoʻokuʻu ʻia e nā pancreatic β-cells). Kālaʻi kēia hopena ma ka mea ʻoi a me ka maikaʻi o ka pancreatic β-cells e hoʻomaikaʻi i ka hiki ke pane i ka stimitions physiological o glucose. Hoʻohālikelike ʻia i ka glibenclamide, ka wai haʻahaʻa o ka glimepiride e waiho i ka hoʻokuʻu ʻana o nā dosis haʻahaʻa i ka insulin me ka emi o ka emi o ka glucose, e hōʻike ana i ka hopena o ka extrapancreatic hypoglycemic o ka glimepiride (hoʻonui i ka naʻau o ka naʻau i ka insulin, ka hopena insulinomimetic).

Pūnaewele huna ʻia

E like me nā derivatives sulfonylurea, pili ka glimepiride i ka huna ʻana i ka insulin ma o ka hana ʻana ma nā hāmeʻa pākīpeka huapili o ATP ma nā membranatic β-cell.

ʻO ka ʻokoʻa mai nā derivatives sulfonylurea ʻē aʻe o ka pilina pili o ka glimepiride me kahi protein e loaʻa ana ke kaumaha molihope o 65 kilodaltons a waiho ʻia i nā membranes o cells-cells. ʻO kēia hopena o ka glimepiride e hiki iā ʻoe ke hoʻoponopono i ke kaʻina hana o ke pani ʻana / i wehe ʻana i nā kaohi pākaʻala o ATP-sensitif. Hoʻopau ʻo Amaryl i nā pāheʻe potasi, kahi e hiki ai i ka depolarization o β-cell, ke wehe i nā awelika calcium-sensitens a me ke kahe e kahe ana o ka calcium i loko o ka hale. Me ka hoʻonui nui o ka calcium calcium intracellular, hoʻōla ʻia ka insulin ma ka exocytosis. No ka hoʻohālikelike ʻana me ka glibenclamide, hoʻopili wikiwiki ka glimepiride i nā manawa pinepine a hoʻokuʻu ʻia mai nā pilina me nā protein e pili ana. ʻO ka manawa, ke kiʻekiʻe o ka hoʻonaninani o ka glimepiride me ka protein e hoʻolaha i ka hoʻonaninani 'of-cell i ka glucose, a mālama pū iā lākou mai ka desensitization a me ka wikiwiki wikiwiki.

Ka hopena Insulinomimetic

Hoʻohālikelike ka hopena o ka glimepiride i ka hopena o ka insulin i ka kaʻina o ka huki ʻana o ka glucose e nā huakaʻi peripheral a me kona puka ʻana mai ka ate.

Hoʻopili nā ʻiʻo peripheral i ka glucose ma o ka halihali ʻana i loko o nā pūpū a me nā adipocytes. Hoʻonui ka Glimepiride i ka nui o nā molekik e lawe ana i ka glucose a hoʻoulu i ka phospholipase-glycosylphosphatidylinositol-sp C. C. Ma muli o kēia, hoʻemi ka ea o ka calcium intacellular, ka mea i hōʻemi i ka protein kinase ʻO kahi hana a me ka hoʻoulu ʻana i ka metabolism glucose. Ma lalo o ka hopena o ka glimepiride, e hoʻoneʻe ʻia ka hopena o ka glucose mai ka puʻupaʻa (ma muli o ka hoʻonui o ka ʻike o ka fructose-2,6-bisphosphate e hoʻokaʻa ana i ka glucoseoneogenesis).

ʻO ka hopena antiatherogenic

Hoʻoikaika ʻo Glimepiride i ka ʻike o nā lipids, ka hoʻokaʻawaleʻana i ka hoʻouluʻana o ka malondialdehyde i loko o ke koko, ma ke ʻano o ka hōʻemi nui o lipid peroxidation. I nā noiʻi holoholona, ua ʻike ʻia ka lawe nui ʻana i ka glimepiride i ka hoʻokumu ʻana i nā pā plio atherosclerotic.

Hāʻawi ʻo Glimepiride i ka hōʻemi o ka nui o ka hoʻonaninohauʻelima o ka oxidative stress ʻano o ka type 2 diabetes mellitus, hoʻonui i ka keokeo o ka endogenous alpha-tocopherol, a me ka hana o ka catalase, ka puʻuwai diseroxide a me ka glutathione peroxidase.

Nā hopena Cardiovascular

Hoʻomoʻa ka huahelu o nā sulfonylureas i ke kūlana o ka ʻōnaehana cardiovascular, e pā ana i nā kahawai pālato e pili ana i ka ATP. Hoʻohālikelike ʻia i nā derivatives sulfonylurea, ʻike ʻia ka glimepiride e kahi hopena haʻahaʻa loa i ka ʻōnaehana cardiovascular, ka mea e pili ai me kahi kaʻina hana pono o kona pili me nā protein o nā kaila pāpaʻomaʻo ATP-sensitive.

ʻO ka hopena haʻahaʻa liʻiliʻi loa i nā limahana olakino he 0.6 mg. He hopena hou ka hopena o ka glimepiride a hilinaʻi ma ka hopena.

Ke lawe nei iā Amaril, mālama ʻia ka hopena o ka physiological i ka hana kino (hoʻohaʻahaʻa i ka huna ʻana i ka insulin).

ʻAʻohe mea hilinaʻi i ka ʻokoʻa i ka hopena o ka manawa o ka lawe ʻana i ka lāʻau lapaʻau (i lawe pono ʻia ma mua o kaʻai a i ʻole 0.5 mau hola ma mua o ka ʻai). Ma ka maʻi mellitus, hoʻokahi hoʻokele hoʻomohala ʻo Amaril e hiki ke hāʻawi i ka control metabolic nui no 1 lā. Ma kahi noiʻi hauoli e pili ana i nā mea hana 16 mau mea e hōʻeha nei i ka hana ʻole o ka renal (hoʻopiha i ka hana ʻana mai 4 a 79 ml / min), ʻoi aku ka nui o ka hoʻomaʻemaʻe metabola ma 12 nā mea maʻi.

Hoʻohui hui ʻia me ka metformin

Me ka lawa ʻole o ka hoʻokalakupua metabola i nā mea maʻi e lawe i ka nui loa o ka glimepiride, aia ke ʻano o ka hui pū ʻana me ka metformin a me ka glimepiride. I loko o nā haʻawina ʻelua, hōʻike nā hui hoʻohui i ka nui o ka mālama o ka metabolic i hoʻohālikelike ʻia me ka hoʻokaʻawale ʻana i kēlā me kēia lāʻau lapaʻau.

Hoʻohui hui me ka insulin

Me ka lawa ʻole o ka hoʻokalakupua metabola i nā mea maʻi e lawe i ka nui loa o ka glimepiride, aia ke ʻano o ka hui pū ʻana me ka metformin a me ka insulin. I loko o nā haʻawina ʻelua, hōʻike nā hui hoʻohui i ka nui o ka kaohi ma ka metabolic e like me ka insulin monotherapy. Eia kekahi, pono ke ʻano o ka hui ʻana i ka haʻahaʻa o ka insulin.

Lapaʻau lāʻau

I ka hihia o ka hoʻokele hou ʻana o glimepiride ma kahi o ka nui o 4 mg i kēlā me kēia lā, ʻo ka manawa e hōʻea ai i ka nui o ka piʻi ʻana o ka nui o ke koko he ʻelima mau hola, a ʻo ka nui o ka plasma wela o ka waiwai hana he 309 ng / ml. ʻO ka kukuna plasma nui loa o ka glimepiride a me ka mahele ma lalo o ke kihi pharmacokinetic "kālai" - manawa "linearly hilinaʻi i ka maʻa o Amaril. Me ka hoʻokele waha o glimepiride, ʻike ʻia ka piha bioavailability piha. ʻAʻole hilinaʻi nui ʻo Absorption i ka kaʻai ʻana o ka meaʻai (koe wale nō kahi lohi i kahi hoʻolimalima.) Loaʻa iā Glimepiride kahi haʻahaʻa haʻahaʻa loa o ka hoʻolaha ((

8.8 L), kahi hoʻohālike e like me ka nui o ka hoʻoili ʻana o ka albumin. Hōʻikeʻike ka ʻano hana e kahi kiʻekiʻe kiʻekiʻe o ka hoʻopili ʻana i nā protein plasma (ma luna o 99%) a me ka haʻahaʻa haʻahaʻa (

48 ml / min). Hoʻomaopopo ʻia e ka serum konsentrate me ka hoʻokele mau ʻana iā Amaril, ʻo ka hapalua hapalua ola mai 5 a 8 mau hola. I ka hihia o nāosa kiʻekiʻe, hoʻonui ka hapalua hapalua.

Ma muli o kahi hoʻokele hoʻokahi o ka hoʻopiʻi glimepiride, ʻo 58% o ka hopena e hoʻopau ʻia e nā palaka, a me 35% o ka hopena ma o nā ʻāpana. I ka urine, ʻaʻole i ʻike ʻia ka glimepiride i loli.

I ka hoʻopiʻi a me ka urine, ʻike ʻia nā ʻelua metabolites i kūkulu ʻia i loko o ka puʻuwai (ʻoi aku ka nui o ke komo ʻana o ka isoenzyme CYP2C9), kekahi o ia mea he derboative carboxy, a ʻo kekahi ʻē aʻe kahi kahi hydroxy. Ma hope o ka lawelawe waha, ua pau ka hapalua o ka noho ʻana o kēia mau metabolites ʻo 5-6 a me 3-5 mau hola, kēlā.

ʻO ke mea ikaika e hele ai i ka pale o ka placental a hoʻopili ʻia i ka waiū umauma.

Ke hoʻohālikelike nei i nā helu hoʻokahi a me nā helu he nui o ka glimepiride, ʻaʻohe ʻano nui o nā ʻōkuhi pharmacokinetic, a ʻo kā lākou ʻano haʻahaʻa haʻahaʻa i ʻike ʻia i nā mea maʻi. ʻAʻohe mea hōʻemi nui o nā mea ikaika.

I nā mea maʻi o nā hui like ʻole a me nā kāne, ua like nā ʻāpana pharmacokinetic. I ka hihia o nā hana renal impaired (me ka clearance hoʻohaʻahaʻa haʻahaʻa), hiki i ka nui o ke kahena o ka glimepiride a me kahi hoʻohaʻahaʻa ʻana i ka ʻike o ka hoʻokaʻina o ka serum koko. I nā loli āpau, ʻo kēia ka mea iʻoi aku ka kiʻekiʻe o ka hoʻonuiʻana i ka lāʻau lapaʻau ma muli o ka palena o ka mau kao o ka protein. Ka mea, ma kēia ʻāpana o nā mea maʻi ʻaʻohe pilikia o ka Amaril cumulation.

Nā hōʻailona no ka hoʻohana ʻana

Wahi a nā ʻōkuhi, ua ʻō ʻia ʻo Amaryl no ka maʻi diabetes mellitus type 2 (non-insulin-dependant diabetes).

ʻO ka glimepiride mea waiwai e hoʻoikaika i ka hana o ka insulin e ka pancreas a me ke komo ʻana i ka koko. ʻO ka insulin, ma ka huli ʻana, e hōʻemi i ka nui o ke kō i loko o ke koko. Hoʻomaikaʻi ʻo Glimepiride i nā kaohi ʻai me nā ʻaihue, a he mea kōkua nō hoʻi i ka pale ʻana i ka hoʻokumu ʻia ʻana o nā papa atherosclerotic ma nā paia o nā kīʻaha koko.

Nā Hoʻohui

ʻAmelike ʻia ʻo Amaryl i kēia maʻi:

ʻO ka maʻi diabetes mellitus 1 (ke hilinaʻi-insulin),
Diose moho ketoacidosis (kahi hoʻopiʻi o ke ʻano maʻi type 1)
ʻO kaʻeha huehue a me nā maʻi pūpū,
ʻO ka coma maʻi maʻi a me kāna precoma,
Glabose-galactose malabsorption, hemahema lactase, galolose intolerance,
Nā makahiki o nā keiki
Haki kūlohelohe i kekahi ʻāpana Amaril,
ʻŌpū a me ka lactation.

Nā ʻōkuhi no ka hoʻohana ʻana iā Amaril: kaʻina a me ka helu ʻana

Wahi a nā ʻōlelo aʻoaʻo, pono e hoʻokaʻawale iā ʻAaryary me ka hana ʻole ʻana, ma mua koke o ka wā kakahiaka a inu ʻoe i ka wai nui (ma ka liʻiliʻi he ½ kīʻaha). Pono ka lawe ʻana i kahi lāʻau lapaʻau e hoʻopili ʻia i ka ʻai, inā ʻaʻole e hōʻemi ʻia ka nui o ka hoʻāʻo ʻana i ke kō.

Koho ʻia ka nui o ka maʻi no kēlā me kēia maʻi e ka neʻe i ka kauka, e kau ana i ka pae o ke kō i loko o ke koko.

Hoʻomaka kūleʻa nā maʻi e ka hapa haʻahaʻa o Amaril - 1 mg i kēlā me kēia lā. Aia i ke kūlana o ka mea maʻi, hiki i ke kauka ke neʻe lohi (hoʻokahi i kēlā me kēia mau hebedoma 1-2) e hoʻonui i ka dosis o Amaril, e hele ana ma hope o ke kumumanaʻo: 1-2-3-4-6 mg. ʻO nā maʻa maʻamau he 1-4 mg o kēlā me kēia lā.

Inā poina e ka mea maʻi e hoʻolohe i nā laʻai i kēlā me kēia lā, a laila ʻaʻole e hoʻonui ʻia ka hopena hou. Pono e kūkākūkā ʻia nā hana ma kahi hihia o ka hōʻemi ʻole o ka hoʻoponopono ʻana i ka lāʻau lapaʻau.

I ka wā o Amaril ka hoʻohana pono ʻana i ka mālama koko.

Ke keu

I ka hihia o ka overdose a i ʻole me ka lōʻihi o ka mālama ʻana me nā dosis kiʻekiʻe o ka glimepiride, aia kahi hopena o ka hoʻouluʻana i ka hypoglycemia koʻikoʻi me kahi hopena e ola nei.

Ke kali nei i kahi maʻi overdose, ʻimi koke i ke kōkua olakino. Ma aneʻa mau loa, hiki ke hoʻokuʻu koke ʻia ka hypoglycemia e ka lawe koke ʻana i nā minamina (kahi ʻāpana o ke kō, ke kō, ka ʻona, a me nā wai momona maikaʻi paha), no laila e pono i ka mea maʻi me nā ʻāpana o 4 o ke kō me kāna (20 g glucose).ʻO nā mea momona loa i ka mālama ʻana i ka hypoglycemia hikiʻole.

Pono ka mea maʻi ma lalo o ka mālama koʻikoʻi olakino a hiki i ke kauka ke hoʻoholo nei ʻaʻole he pilikia o nā ʻōpiopio. Pono e noʻonoʻo i ka hiki o ka hoʻomau i ka hypoglycemia ma hope o ka hoʻihoʻi o ka glucose i ke koko.

Ke mālama nei i kahi mea maʻi me ka maʻi maʻi me nā kauka like ʻole (no ka laʻana, ma ka hopena pule a i ka wā i hoʻokipa ʻia i ka haukapila ma muli o kahi ulia), pono ia e hoʻomaopopo e pili ana i kona maʻi, a me ka pili o ka lāʻau ma mua.

I kekahi mau hihia, koi paha ka hila i ka haukapila. ʻO kahi overdose nui me kahi hopena koʻikoʻi (ʻoi aku ka ʻike o nā pilikia neurological koʻikoʻi) e pili ana i nā kūlana olakino pōʻaiapau a koi pono i ka hoʻokipa āpau a me ka mālama maʻi.

Aia ma ka mea i ʻike ʻole ʻia i ka mea ʻike ʻole, ua hōʻike ʻia kahi hopena hoʻonaninani o ka glucose (dextrose) o 20% i loko o ka intravenously (no nā pākeke, ke hōʻike ʻia kahi nui o 40 ml o ka hopena). I ka poʻe pākeke, he koho lapaʻau hou aku i loko o kahi kikowaena intramuscular a subcutaneous o glucagon (ma ke ʻano o ka 0.5 a 1 mg).

Inā hana ʻino ʻia ʻo Amaril e nā keiki ʻōpio a i nā pēpē, pono e hoʻoponopono ʻia ka nui o ka dextrose i ka wā o ka hypoglycemia me ka noʻonoʻo ʻana i ka hopena o ka mea pili i ka hyperglycemia. Pono e hoʻokomo ʻia ka dextrose ma lalo o ka mālama mau ʻana i ka glucose i loko o ke koko.

I kahi hihia o ka overdose, gastage lavage a me ke koho ʻana i ke kalepa e koi ʻia ai.

ʻO ka hoʻihoʻi wikiwiki o ka glucose koko ka mea e koi ai i ka lawelawe ʻoki i loko o ka hoʻohaʻahaʻa haʻahaʻa o ka hopena o ka dextrose i mea e pale ai i ka hana hou o ka hypoglycemia. I nā poʻe maʻi āpau, e mālama ʻia ka ʻike o ka glucose i ke koko no 1 mau lā. I nā hihia koʻikoʻi me ka papa o ka hypoglycemia lōʻihi, ʻo ka nui o ka hoʻohaʻahaʻa i ka glucose i kahi kiʻekiʻe hypoglycemic mau no kekahi mau lā.

ʻŌpū a me ka lactation

I ka wā hāpai, ua contraindicated ke hoʻohana ʻana o Amaril. Me ka wahine hāpai i hoʻolālā ʻia a i ʻole ka hoʻomaka ʻana o ka wā hāpai i ka wā o ka lāʻau lapaʻau, pono e hoʻoneʻe i ka wahine i ka ʻohi ʻana i ka insulin.

No ka mea ua hoʻopili ʻia ka glimepiride ma ka umauma umauma, ua contraindicated ka hoʻohana ʻana o Amaril i ka umauma maʻi. I kēia hihia, ua hōʻike ʻia ka hoʻololi ʻana i ka insulin insulin a i ʻole ka pau ʻana o ka hana umauma.

Hoʻohui nūhou

Hoʻopili ʻia ka Glimepiride e ka isoenzyme CYP2C9 o ka pūnaehana cytochrome P4502C9, pono e noʻonoʻo pono i ka wā e hoʻohana pū ʻia ai e nā inducers (e ..gif rifampicin) a i ʻole CYP2C9 inhibitors (e.g. fluconazole). Ke hui pū ʻia me nā lāʻau lapaʻau e hiki mai ana, hiki i ka nui o ke ʻano o ka hana hypoglycemic, a i kekahi mau hanana ka hoʻomohala ʻana o ka hypoglycemia ma muli o kēia: nā insulin a me nā lāʻau hypoglycemic ʻē aʻe no ka lawelawe waha, angiotensin-hoʻohuli i ka hoʻohui o nā enzyme, hormones sex sex, anabolic steroid, Coumarin derivatives, chloramphenicol, disopramide, , feniramidol, fenfluramine, fluoxetine, fibrates, ifosfamide, guanethidine, monoamine oxidase inhibitors, fluconazole, pentoxifylline (in Waiū i loa parenteral nā māhele), pa-aminosalicylicʻakika, azapropazone, phenylbutazone, probenecid, oxyphenbutazone, salicylates, quinolones, clarithromycin, sulfinpyrazone, tetracyclines, sulfonamides, trofosfamide, tritokvalin.

Ke hui pū ʻia me nā lāʻau lapaʻau i hōʻike ʻia ma lalo nei, hiki ke nawaliwali nā hana hypoglycemic, a me ka hoʻonui ʻana o ka glucose koko e pili ana me ia: acetazolamide, glucocorticosteroids, barbiturates, diuretics, epinephrine, nā huina hou aʻehaʻāmatic, glucagon, nicotinic acid (kiʻekiʻe nā wai), laxatives (ma nā hihia o ka hoʻohana lōʻihi), progestogens, estrogens, rifampicin, phenytoin, phenothiazines, iodine e pili ana i ka hormone thyroid.

I ka manawa e hoʻohana pū ai me nā beta-blockers, N blockers₂-mistamine receptor, clonidine a me ka reserpine, nā nāwaliwali a me ka hoʻonui ʻana i ka hopena hypoglycemic o ka glimepiride.

Ke lawe nei i nā lāʻau lapaʻau sympatholytic (beta-blockers, guanethidine, reserpine a me clonidine), hōʻailona paha o ka adrenergic counterregulation me hypoglycemia i hala a hōʻemi paha.

ʻO ka hoʻohana pū ʻana o ka glimepiride a me nā derivatives Coumarin hiki ke hoʻoikaika a hoʻonāwaliwali i ka hopena o ka hopena o ka hopena.

I ka loaʻa ʻana o kahi hoʻohana kolohe a i ʻole ka waiʻona, hiki i ka hopena hypoglycemic a glimepiride ke hoʻonui a emi a emi iho.

E hoʻohana me nā ʻōmole bile acidest: i ka huila kime, ke hoʻopili ana i ka glimepiride, e hoʻemi ana i kona lawe ʻana mai ka gastrointestinal tract, me ka hoʻohana ʻana o glimepiride 4 mau hola ma mua o ka lawe ʻana i ka pilina huila ʻaʻole i kākau ʻia.

ʻO kēia mau lāʻau lapaʻau e hoʻohālikelike i nā mea hoʻohālike o Amaril: Glemaz, Glymedeks, Meglimid, Diamerid, Glemauno.

Nā Manaʻo Amaril

Hōʻike ka hōʻike ʻana o Amaril e ke kī i ke olakino o ka lāʻau lapaʻau ke koho pono o ka nui lāʻau a me ka hoʻoponopono regimen. Ma ka manawa like, aia kekahi mau lono e pili ana i ka ʻike ma ka hoʻomaka mua ʻana o ka lawe ʻana iā Amaril i nā mea maʻi, ua loli nui ke kaʻe o ke koko. Wahi a nā poʻe loea, hiki ke hoʻokuʻi ʻia kēia ʻanoʻano ma ka hoʻoponopono ʻana i ka maʻi ʻoka e kahi kauka (me ka loaʻa ʻole o ka lāʻau lapaʻau, ʻike nui i ka hoʻopiʻi ʻana i nā hoʻopiʻi o ka maʻi nui).

ʻO nā mea waiwai nui o ka lāʻau lapaʻau

ʻO ka mea hana nui ka ʻāpana o ka lāʻau - glimepiride (inoa Latin - Glimepiride) pili ikaika i ka hoʻokuʻu ʻana i ka insulin.

Mahalo i kēia māhele, ua pono ka hopena o ka lāʻau lapaʻau.

Me ka hoʻokuʻu i nā hormone mai nā pū beta, he nui ka loaʻa ʻana o ka nui o ke kōʻai koko. Hoʻopili kahi ʻano hana like me kahi holomua o ka hoʻololi ʻana i nā maʻi beta i ka glucose.

Ma kahi o nā mea hana koʻikoʻi, hiki i nā mea hou ke hoʻohui i ke ʻano o ka lāʻau lapaʻau.

povidone
laktosa lactose,
indigo carmine
konekena stearate,
cellulose microcrystalline.

Hoʻopili ia, hoʻoponopono ka lāʻau i ka hana o ka hormone pancreatic. ʻO kēia ma muli o ka pilina o ke glimepiride a me ka metformin me nā kahe pālolo ma ka membrane cell beta. ʻO ka paʻa ʻana o ka hana ikaika i nā protein e hoʻoponopono i ka hana o ke kahawai, ʻo ia hoʻi, e pani a wehe i ka wehe.

Loaʻa iā Amaryl kahi hopena extrapancreatic - hoʻomaikaʻi i ka hoʻohanaʻana o ka insulin e nā uaua a me ka kiko adipose. Hana ʻia kēia ma muli o ke kāohi ʻana i nā kahe pākela i loko o nā membrane cell a me ka hoʻonui nui o ka kōomi o ka calcium ma nā puna. Hoʻopilikia ka hopena extrapancreatic i kahi hōʻemi o ka pale ʻana i ka insulin, akā pili pū kekahi i ka hana o ka puʻuwai a me nā kīʻaha koko.

Loaʻa ka ʻike kiʻekiʻe loa o ka hana ikaika me ka hoʻohana pinepine. No ka laʻana, i ka wā e lawe ai i ka 4 mg o ka glimepiride i kēlā me kēia lā, loaʻa ka minamina kiʻekiʻe loa i nā hola 2 mau.

Loaʻa ka kōpili piha o ka lāʻau i ka wā i lawe ʻia ai. Hoʻololi ka ʻai i ka meaʻai i ke kaʻina o ka assimilation o ka lāʻau lapaʻau, akā hiki ke mālama ʻia kēia hopena. Ke hele nei ka hana o ka glimepiride i loko o nā ʻōpū a me nā kau.

ʻO ka papa inoa o nā hōʻailona a me nā contraindications no ke komo ʻana

ʻAe nā ʻōlelo pili iā Amaryl no ka hoʻohana ʻana. ʻO ka mea nui, ʻo ka mālama ʻana i ka maʻi diabetes 2. Ua hoʻāpono ʻia ʻo Amaril no nā poʻe maʻi ʻaʻohe pono i nā inikini insulin, a no ka poʻe i hōʻike ʻia i ka insulin e hoʻomaikaʻi i ko lākou pono.

Ma ka mālamaʻana i ka maʻi maʻi, ua hoʻokaʻawale ʻia nā papa ʻo Amaryl e like me ka lāʻau nui. Akā me kaʻole o ka hoʻokalakupua metabole (ʻoi aku inā ua kuhikuhi ʻia ka mea maʻi i ka nui o ka lāʻau), ʻo Glimepiride i hui pū me Metformin i kuhikuhi ʻia. Hiki i kēia ke hoʻomaikaʻi i ka mālama metabolic. I kēia hihia, ʻoi aku ka maikaʻi o nā hopena i hoʻohālikelike ʻia i nā mea i loaʻa me kahi hoʻokaʻawale ʻana i nā lāʻau lapaʻau.

ʻO ka hopena maikaʻi e loaʻa ana ma muli o ka hopena paʻakikī me ka hoʻohana ʻana iā Glimepiride a me Metformin i hōʻemi ʻia ka hoʻomohala ʻana o ka lāʻau lapaʻau ʻo ʻAmaryl M. Hāʻawi ʻia kahi lāʻau lapaʻau no kēia lāʻau inā he mālama i ka maʻi mellitus me nā lāʻau paʻakikī, pono ia no nā maʻi.

Hiki ke lawe ʻia i ka lāʻau hoʻohaʻahaʻa gula amaril i nā maʻi nā mea pono i nā inikua maʻamau. I ka manawa like, hoʻomaikaʻi pū ka mana metabolic, akā e hoʻemi ʻia ka nui o nā kime o ka glimepiride.

E like me nā lāʻau lapaʻau, ʻaʻole hiki ke manaʻo ʻia ka lāʻau lapaʻau. He mau contraindications a Amaril, a nui loa kā lākou papa inoa.

ʻO ka mea mua, ke ʻōlelo ʻia e makaʻala i ka lawe ʻana i ka lāʻau lapaʻau ma ka hana mua o ka mālama ʻana: i ka manawa o kēia manawa, ke kū mau nei ke kao o ka emi o ke kahe o ka glucose. Inā hala ka wā i noho ka pilikia o ka hypoglycemia, ua pono ke hoʻololi i ke koʻola lāʻau lapaʻau a i ʻole ka make ʻana o Amaril. Pono ʻoe e makaʻala a me kekahi mau maʻi, kahi ʻano kūpono ʻole, nā meaʻai ʻole ʻia.

ʻO nā maʻi i hala (a i ʻole nā kūlana o ke kino) nā contraindications nui loa i ke koho ʻana iā Amaril:

ʻO kahi mea maʻi coma a i ʻole ka kūpuna.
Ketoacidosis.
ʻOi ka maʻi nui a me nā maʻi pūpū.
Intolerance a hypersensitivity paha i nā mea nui a ʻokoʻa paha o ka lāʻau.
Nā maʻi hoʻoili hoʻoili (lactose intolerance, lactase deficiency, etc.).
Kahawai I ka wā hoʻolālā i ka wā hāpai, pono e sui ke ʻano o ka hoʻoponopono. Lawe ʻia ka mea maʻi i nā inikua insulin, ʻaʻole i kuhikuhi ʻia ka lāʻau lapaʻau.
I ka wā o ka hōʻuluʻulu ʻana, e hoʻomau ka hana o ka insulin. Inā no kahi kumu kūpono ʻole kēia regimen lāʻau, ua ʻōlelo ʻia ʻo Amaril i ka mea maʻi, akā uaāpono ʻia e pani i ka lactation.

ʻAʻole i kuhikuhi ʻia kahi lāʻau lapaʻau no ka mālama ʻana i nā maʻi maʻi maʻamau. ʻO kahi contraindication kūpono loa nā makahiki o nā keiki. ʻAʻohe data lapaʻau e pili ana i ka hoʻokuʻu ʻana i nā lāʻau ma nā keiki.

No laila, no ka mālamaʻana i ka maʻi maʻi i nā keiki, ʻoi aku ke ʻano o ka analogue palekana o ka lāʻau.

ʻO nā hopena ʻaoʻao o ka hoʻohana ʻana i ka huahana

I ke hopena o ka lawe ʻana iā Amaril, hiki paha i nā hopena hopena.

I kekahi mau hihia, aia ka manawa i hana hewa ai i nā ʻokoʻa āpau a me nā ʻōnaehana o ke kino.

Ma ka ʻaoʻao o ka metabolism, ua ʻike ʻia nā hopena hypoglycemic. Hoʻohā pinepine ʻia lākou i mua, akā hikiʻole ke mālama ʻia.

ʻO kekahi mau lāʻau maʻi maʻi ma kahi e pilikia ai nā kinipōpō ma waena.

ʻO nā mea lawe iā Amaryl i loaʻa nā hōʻailona like ʻole:

āhāhuʻe
nānā nānā
kokaʻaʻa ʻana
e lohi ana i ka wailua
hiamoe hiamoe
hūnā a nalowale paha ka ʻike
kūlana kaumaha
hoʻonā wahaʻōlelo
hopohopo, hopohopo, etc.

ʻO ka hopena o ka lawe ʻana i ka lāʻau lapaʻau e like me ka hōʻino ʻole o ka digestive tract. Hiki iā lākou ke hōʻike ʻia e ka ʻeha ma ka ʻōpū a i ʻole ʻōpū, nīpona, nā hua ʻino, ka luaʻi, hoʻonui ʻia ka pōloli.

Ma muli o nā hopena o ka glimepiride, hiki i ke kauʻana i ke kiʻekiʻe o ka glucose ka mea hiki ke hoʻopilikia i ka kūlana o nā puna o nā mea ʻike, hiki ke hōʻeha i ka ʻike maka.

E pili ana ka lāʻau lapaʻau i nā kaʻina hana o ke koko, hiki iā ia ke hana i ka pōʻino o nā loli like:

Anemia
ʻO Thrombocytopenia (o kahi ʻano paʻakikī).
Pancytopenia.

ʻOi aku ka maʻamau o nā maʻi kūlohelohe maʻamau:

pohuo
ʻili ka ʻili
ʻulaʻulaʻula o ka ʻili,
vasculitis.

Ma hope o ka lawe ʻana i ka lāʻau lapaʻau Amaril, hoʻomaʻamaʻa pinepine nā maʻi allergy a hele koke me ka mālama kūpono.

Akā ʻoiaiʻo ia he mea nui loa e hoʻomaka i ka mālama ʻana i ka manawa kūpono: ke noho nei ka pōpilikia o ka anaphylactic shock.

Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau

ʻAʻole hiki ke mālama ʻia ka hoʻomaʻamaʻa ʻana me ka ʻole o ka hahai ʻana i nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana iā Amaril. ʻO ke kānāwai koʻikoʻi o ka hoʻokele e pili ʻole i ka papa. E lawe kīkī iā Amaril 3 i ka piha holoʻokoʻa, me ka nui o ka wai i mea e maʻalahi ai ka moni ʻana.

Hoʻomilikino ʻia ka hopena kiʻekiʻe ʻo Amaril no ka mea maʻi. ʻO ka hana nui e hoʻohana ʻia i ke kuhikuhi ʻana i ka lāʻau lapaʻau ka ʻike ʻana o ka glucose i loko o ke koko. Hoʻolaha ʻia ka pā liʻiliʻi liʻiliʻi ʻoi ke hiki ke kōkua i ka hoʻāla maʻamau o ka kaohi metabolic. Hoʻopili i nā pae glucose, i ka pauku kuhikuhi i ke ala o ka hoʻohana ʻana i ka lāʻau e hōʻike ana i ka mālama mau ʻana i ka pae kūlohelohe wale nō, akā e pono ai hoʻi ka hemoglobin glycated.

Aia paha nā kūlana i ka poina i ka mea maʻi e lawe i nā papa Amaril ma ka manawa. I ia mau hihia, ke hāpai hou nei i ka nui o ka lāʻau lapaʻau ma ka pāpālua ʻia ʻana o ka dosage ʻaʻole ʻia. ʻO ka maʻamau ke kūlike nā ka papaʻaau, ʻaʻole i hoʻonui ʻia nā papa i hala ʻole. ʻOi aku ka maikaʻi o ke kamaʻilio ʻana i ke kauka ma mua e pili ana i nā hana i loko o ia mau kūlana.

Ma ka hana mua no ka mālama ʻana, ua kuhikuhi ʻia nā mea maʻi iā Amaryl 1 mg i kēlā me kēia lā. ʻOi aku ka manawa, inā pono, kahi piʻi lohi i loko o ka lāʻau o ka lāʻau lapaʻau e 1 mg e ʻae ʻia, e piʻi mua o 6 mg i kēlā me kēia lā, a laila ma ka 8 mg. Me ka kaohi o ka maʻi maʻamau, ʻaʻole nui ka nui o ka nui ma mua o 4 mg i ka lā. Nui ka nui ma kahi o ka 6 mg i kēlā me kēia lā e loaʻa pinepine ai ka hoʻomaikaʻi. ʻO ka nui o ka lāʻau i 8 mg e kuhikuhi ʻia i nā kūlana kūʻokoʻa.

Hoʻoholo ʻia ka manawa ma waena o kēlā me kēia hoʻonui i ka dosage e ke ʻano o ka mea maʻi a me ka hoʻokō pono o ka nui o nā lāʻau i lawe ʻia, akā ʻaʻole hoʻi e emi ma mua o 1-2 pule.

Pono e lawe i ka lāʻau lapaʻau ma hope o ka ʻai ʻana, me ka mea hiki ke ʻano he hypoglycemia.

ʻO ka lāʻau hoʻohui Amaryl M e lawe ʻia e like me ke kānāwai. Ua hoʻokaʻawale ʻia ka nui o ka lāʻau o ka lāʻau lapaʻau i hōʻike ʻia i ʻelua mau ʻano: i ke kakahiaka a me ke ahiahi, a lawe ʻia a piha. I ka manawa pinepine, ua ʻōlelo ʻia e nā maʻi e lawe iā Amaril 2m + 500 mg.

Kahi ʻia ka nui o Amaril mai ka maʻi maʻi i nā maʻi maʻi ma o ka makaʻala loa, a e mālama ʻia ana ka mālama ʻana me ka mālama mau ʻana i nā kuli.

Hoʻohui hou i ka ʻike

I ke koho ʻana iā Amaril a i ʻole Amaril M, ʻaʻole pono ke kauka e hāʻawi i nā ʻōlelo e pili ana i ka hoʻohana pono ʻana i ka lāʻau lapaʻau, akā e hoʻomanaʻo pū no nā hopena kūpono paha. Pono ka nānā kikoʻī e pili i ka hopena o ka hypoglycemia, hiki i ka hoʻomohala inā hoʻopoina ka mea maʻi i ka ʻai koke ma hope o ka lawe ʻana iā Amaril. I mea e pale aku ai ma ka hypoglycemia, ʻoi aku ka maikaʻi o ka loaʻa ʻana o ka ʻāpana me ke kō a mālama paha me ʻoe.

Hoʻopili i nā kiʻekiʻe o ke kō a me ke kūpaʻa glucose i loko o ka pāʻai, pono e ʻike pinepine ka mea maʻi i ka hana o nā pūpū a me ka ate.

ʻO kahi nīnau maʻamau e pili paha i hiki ke inu i ka waiʻona i ka wā o ka maʻi me Amaril. He mea kūpono ke hoʻomanaʻo o ka waiʻona i ka wā maʻi ʻole i ka wā o ka mālama ʻana i ka maʻi diabetes a ʻaʻole hiki ke hoʻohui pū me ka hapa nui o nā lāʻau lapaʻau. Aʻo Amaril pū kekahi o kēlā. Hiki ke loaʻa ʻole nā hopena o ka lawe ʻana i ka lāʻau lapaʻau a me ka waiʻona i ka manawa like. I kekahi mau hihia, ulu nui ka ulu o ka lāʻau, a ma nā mea ʻē aʻe ua hōʻemi nui ʻia ia. No laila, i ka wā o ka mālama ʻana, pono ʻoe e haʻalele i ka waiʻona a me ka mea inu wai.

E like me ka launa pū ʻana o Amaril me nā lāʻau lapaʻau ʻē aʻe, e hilinaʻi nei nā mea a pau ma ke ʻano o ka lāʻau lapaʻau. ʻO ka lawe ʻana i kekahi mau lāʻau lapaʻau e hoʻomaikaʻi ai i ka hopena o Amaril, kekahi - e hōʻemi ana i ka pono. ʻO kahi papa inoa o kēlā mau lāʻau a me nā lāʻau ʻē aʻe e ākea nui. No laila, inā pono, e lawe i nā lāʻau e ae, he mea pono e hōʻike i ke kauka hele e pili ana i ka wā maʻi a ua lawe ʻia ka lāʻau lapaʻau. I kēia hihia, hiki i ke kauka ke koho i kahi lāʻau lapaʻau i ka hopena ʻaʻole i ka hopena koʻikoʻi o ka hopena o Amaril.

Inā he hopena like paha, pono ʻoe e hoʻōki i ka lāʻau lapaʻau a nīnau aku i kahi kauka.

Hiki i ke kauka ke kākahi i nā ʻōhua Amaril kūpono.

Nā hōʻikeʻike e pili ana i ka lāʻau lapaʻau

I ka hoʻohanaʻana o Amaryl no ka maʻi diabetes type 2, loaʻa nā loiloi maikaʻi mai nā mea maʻi. Hōʻoia kēia i ka mea, me ka dosis kūpono, hoʻōla hakakā ka lāʻau lapaʻau hyperglycemia.

Hoʻohui hou i ka hana pono, ua nui nā mea kūʻai aku i kapa aku i nā ʻano like ʻole o nā papa i ke ʻano maikaʻi o ka lāʻau - kōkua kēia i ʻole e hoʻokau hewa ʻole i ka lāʻau lapaʻau me nā ʻano like ʻole o ka glimepiride.

ʻO nā loiloi i loaʻa iā Amaril i hōʻoia ai ʻaʻole wale i kona pono, akā akā no ka ʻaoʻao kino i hōʻike ʻia i nā ʻōlelo kuhikuhi iā Amaril.

I ka manawa pinepine, nā poʻe maʻi e lawe nei i ka lāʻau lapaʻau e hōʻike i nā hōʻailona o ka hypoglycemia:

Kaumo luhi.
Tremor.
E haalulu ana a puni ke kino.
ʻʻAla
Hoʻonui ka momona.

ʻO ka pinepine, ma muli o ka hypoglycemia i ka mellitus maʻi diabetes, aia kahi pōʻino o ka haʻalele ʻana i ka ʻike. No laila, ʻo ka poʻe e lawe iā Amaril e hoʻomau mau i nā huahana a pau i ke kō (no ka laʻana, ka ʻoluʻolu) me lākou, no laila, inā pono, hiki iā lākou ke hoʻonui i nā nui o ke kō a hoʻomaikaʻi i ko lākou maikaʻi. Eia naʻe, e like me nā kauka, ʻo ka hoʻololi ʻana i ke kaona o ke kō, ʻaʻole ia kahi hōʻailona o ka maikaʻi ʻole o ka lāʻau. Ke kū ʻia kēlā mau ʻōuli, lawa ia e hoʻoponopono i ke ʻano.

ʻO kahi pilikia maʻamau no nā poʻe mākaʻi e koi ʻia ana e lawe i nā ʻāpana hypoglycemic kahi mea ʻino loa i ka wā e lawe ana i ka kaʻa. Hōʻike ʻia kahi hopena like i loko o nā ʻōkuhi i ka papa inoa o nā hopena like ʻole. Hōʻike ʻia ka emi ʻana o ka hopena i ka hopena o ka glimepiride ma ka wahī.

Ma waena o nā mea maʻi me ka maʻi ʻōpiopio kahiko, i nā loiloi ʻo Amaril, nui ka mea i ʻike i kekahi wahi maikaʻi ʻole: ʻoiai ke kūpono me ka haʻahaʻa ʻo Amaril, e hōʻemi nui ka lāʻau lapaʻau, no ka mea nui ke kumukūʻai o ka lāʻau lapaʻau ma mua o kekahi mau analogue, a me ka Lūkini hoʻi. hana ʻana.

Kūʻai a me nā helu o ka lāʻau lapaʻau

Hiki iā ʻoe ke kūʻai i ka lāʻau lapaʻau ʻo Amaril ma loko o kahi kīhāpai maʻamau o ke kūlanakauhale, akā hoʻokahi hoʻokahi mea hoʻāhu: ʻaʻole kūʻai ʻia. E like me nā mea āpau antidiabetic, pono ʻoe e hōʻike i kahi papa hana e kūʻai aku iā Amaryl.

ʻO kekahi nīnau nui e makemake i nā maʻi maʻi he nui ka nui o ke kumukūʻai o Amaril. ʻO ke kumukūʻai o ka lāʻau lapaʻau i kēia hihia e hilinaʻi ʻia ana i ka helu o nā papa i loko o ka pākana a me ka dole o ka lāʻau lapaʻau. No laila, no ka laʻana, kahi pākana o ka lāʻau no nā papa he 30, e hilinaʻi ana ma ka ʻano lāʻau, mai 200 a 850 mau rubles. I ka manawa like, ʻo Amaril 1 mg e uku i ka awelika o 230-280 mau rubles, ka pōpō o nā papa Amaril 2 mg - 450-560 rubles, 3 mg - no 630-830 rubles. ʻO nā papa nui loa iā Amaril 4 mg 90 pcs. - kūʻai lākou i ka awelika o 870-1080 rubles.

Hiki ke kūʻai aku iā Amaril M no 570-600 rubles. He mea nui e noʻonoʻo no kēlā kumukūʻai hiki iā ʻoe ke kūʻai i ke papa Amaril 2mg + 500 mg. He mea paʻakikī loa ka loaʻa ʻana o kahi haʻahaʻa haʻahaʻa loa (1 mg + 250), ʻoiai he liʻiliʻi loa ia i kuhikuhi ʻia e nā kauka, a ma muli hoʻi, ʻaʻole ia i kūʻai lilo aku.

Nui nā lāʻau lapaʻau like like. ʻO nā mea kikoʻī maʻamau:

No ka laʻana, ua hoʻololi pinepine ʻo Amaril i ka lāʻau lapaʻau Gliclazide (pln - Gliclazide). No ka mea paha ia o kahi hui sulfanylurea. ʻO ka hoʻonohonoho o nā lāʻau lapaʻau ka mea wale nō i ka waiwai ikaika - gliclazide a me nā mea hoʻohui hou. Hoʻokomo ka lāʻau lāʻau i nā pū beta, hoʻomaikaʻi i ka hana o ka insulin. Eia kekahi, pono ka lāʻau lapaʻau me ka edema, ʻoiai e hoʻomaikaʻi i ka microcirculation koko, ke pale aku i ka hoʻopuni platelet, a laila e hōʻemi ana i ka hōʻalo o ka thrombosis a me nā hoʻopiʻi pono.

He aha nā lāʻau lapaʻau hypoglycemic kūpono e haʻi i ka mea loea i ka wikiō ma kēia ʻatikala.

ʻO ka lāʻau lapaʻau ʻo Amaril

No ka lāʻau lapaʻau nā lālā o ka lāʻau lapaʻau a me ka ʻoihana pharmacological o nā lālani hypoglycemic oral o ke kolu o ka wā o ka sulfonylurea. ʻO Amaryl kahi hana lōʻihi loa. ʻO ka hui pū, a me ka hopena nui o ka hana antioxidant a me ka hopena liʻiliʻi i ka ʻōnaehana cardiovascular, ua alakaʻi i ka hoʻohana nui ʻana i ka lāʻau e hakakā i ka maʻi type 2 me ka maikaʻi ʻole o ka metformin monotherapy.

Ka hoʻonohonoho ʻana a me ke ʻano o ka hoʻokuʻu ʻana

Ke hōʻike ʻia nei ka lāʻau lapaʻau ma ka mākeke i nā ʻano like ʻole o ka hoʻokuʻu i kēlā, kēia me ke ʻano no ka mālama ʻana i ka maʻi maʻi, e pili ana i nā ʻano pilikino o ka mea maʻi.

Amaril, 1 mg: oblong pink tablets of a flat form, on both both are an split division, the letter "h ^ ʻoi"Ka nānā" NMK ".
Amaril, 2 mg: papa ʻaʻa oblong ākea o nā ʻaoʻao pālahalaha, ma nā ʻaoʻao ʻelua ke ʻano ka ʻoka hakakā, ka leka "h ^ ʻoi"Ka nānā" NMM ".
Amaril, 3 mg: nā papa papa melemele oblong nā papa papa ʻalelona, ma nā ʻaoʻao ʻelua ke ʻano ka ʻokoʻa, ka leka "h" a me ke kālai "NMN".
Amaril, 4 mg: papa ʻaʻa oblong, kīwaha ma ke ʻano, ma nā ʻaoʻao ʻelua ke kuleana ʻokoʻa, ka leka "h" a me ke kālai "NMO".

lactose monohidrat, sodium carboxymethyl starch, povidone, microcrystalline cellulose, magnesium stearate, dyes ulaula a ʻulaʻoma hoʻoneʻe o ka hao, indigo carmine

ʻLoe a me ke kākele

Lawe ʻia ʻo Amaryl i ka wā ʻai a i ʻole mua o ka papa ʻaina, holoi ʻia me ka wai wai. Ma ka hoʻomaka mua o ke komo ʻana, aia kekahi pilikia o ka hypoglycemia, no laila he mea pono i ka mana o ke kauka. Hoʻoholo ʻia ka hopena o ka glimepiride e nā hopena o ka hoʻoholo ʻana i ka pae o ke kō i loko o ka mimi a me ke koko. Hoʻomaka ka hoʻomakaʻana me kahi papa hoʻokahi (1 mg glimepiride) i ka lā. Eia kekahi, ke ʻike ʻia ka nele o ka glycemic control, e piʻi ka dosage i 2 mg a i ʻole. ʻO ka pilina ma waena o ka hoʻonui ʻana ʻo 1-2 mau pule. ʻO ka maʻa loa he 6 mg i kēlā me kēia lā. Hoʻololi ʻia ka lāʻau lapaʻau e like me kahi kauka wale nō.

ʻAkohala a me ʻAmaryl

He hopena kūpono ka lāʻau lapaʻau i ke kōʻai koko. Kuhi ʻia kēia hana ma ka hoʻoponopono hou ʻia i lalo o ka mana o ka ʻona. Hiki ke hoʻonui a emi paha paha ka hopena hypoglycemic, a he mea paʻakikī loa ia e wānana i ka hopena i hōʻike ʻia, ke alakaʻi nei i ka pāpā ʻana i ka hoʻohana ʻana i ka wai ʻona a lawe ʻole i ka lāʻau.

Nā mea hoʻohālikelike o Amaril

Hoʻololi nā lāʻau lapaʻau i nā lāʻau lapaʻau e pili ana i ka sulfonylurea e kūʻē i ka maʻi diabetes. Kūpono o nā ʻano:

Glimepiride - kahi lāʻau lapaʻau me ka inoa like inoa,
Diagninide - kahi wai lāʻau e hoʻemi ana i ke kō ma muli o ka repaglinide,
NovoNorm - kahi mea halihali lawe i ka lāʻau, ka repaglinide,
ʻO Glidiab - kahi lāʻau lapaʻau Lūkia e pili ana i ka glimepiride,
ʻO ka Diabeton kahi lāʻau lapaʻau i lawe ʻia no ka maʻi diabetes.

ʻO Amaril a i Diabeton - ʻoi aku ka maikaʻi

Ua kuhikuhi ʻia nā lāʻau ʻelua no ka mellitus type 2 a ua loaʻa i nā pā papa. Hoʻonohonoho lākou i ka hana o ka insulin, e hoʻonui i ka naʻau o ka naʻau, hoʻohaʻahaʻa i ka kolesterol a me ka hōʻailona o ke manawa mai ka ʻai ʻana i ka hoʻokuʻu ʻana i ka insulin. Inā hana ka mea maʻi i ka hana renal hana, hōʻemi ka lāʻau lapaʻau i ka nui o ka nui o ka protein i ka pā. ʻO ka ʻokoʻa ma waena o nā lāʻau lapaʻau ke kumukūʻai - ʻoi aku ka hapa o ka maʻi diabetes.