Insulins nordisk hou: hana, hoʻolālā a me nā mea hana
Inoa inoa honua. Insulin.
Ka hoʻonohonoho ʻana a me ke ʻano o ka hoʻokuʻu ʻana. ʻO ka mea ikaika a insulin. ʻO ka hoʻonāʻau uila (1 ml o ka lāʻau lapaʻau he hana he 40 PIECES) o 10 ml i loko o nā hue.
- Ka hana lāʻau lapaʻau
- Nā hōʻailona no ka hoʻohana ʻana
- Nā Hoʻohui
- Nā hopena hopena
Ka hoʻoponopono ʻia ʻana. Ke koho nei i ka pālehu a me ke ʻano o ka insulin i ka ʻano, ke kaumaha a me nā ʻano o ka papa o ka maʻi, ka manawa hoʻomaka a me ka lōʻihi o ka hopena o ke kō. No ka manawa mua, kauoha ʻia ka insulin a ua hoʻoholo ʻia ka hopena maikaʻi loa o ka lāʻau ma kahi kūlana o nā haukapila. ʻO ka dosis hoʻokahi o ka insulin i ka mea maʻi me ka maʻi maʻi maʻi i kaʻi ʻole ʻia e ia me ka insulin ua helu ʻia ʻo ia ma ke ʻano maʻamau, glycemia a me nā glucosuria i kēlā lā, a me ke kaumaha o ka mea maʻi. No laila, ma kahi kūlana maikaʻi o ka maʻi maʻi me ka maʻi mellitus maʻi hou me ka ketoacidosis maʻi ʻole me nā glycemia indeks a hiki i ka 8.33-8.88 mmol / L, hiki ke helu ʻia ka nui o ka inika ma mua o ka inika insulin o 0.25 U / kg o ka paona kino o ka mea maʻi. Lawe ʻia nā haʻawina glycemia ma hope o ka inake mua o ka insulin e hoʻokō ʻia ana i ka wā o kona kiʻekiʻe. Hoʻokumu i ka paʻakikī o ka hopena hypoglycemic o ka hopena mua o ka lāʻau, ua hoʻoholo ʻia nā ʻae e hiki mai ana. Ma kahi o kahi overdose, inā ʻike ka mea maʻi, ua hoʻokomo ʻia ka glucose (gula) i loko, inā i loko o kahi ʻike ʻole ʻole - he hopena intravenous glucose a i ʻole intramuscularly a subcutaneously glucagon. Pono e lūlū ʻia nā hoʻonāukiuki o ka zinc-insulin ma mua o ka hoʻohana ʻana a hoʻopaʻa ʻia koke ma hope o ka ʻili ʻili ʻana.
Nā hopena hopena. He kūlana hypoglycemic i hele pū me ka pōloli, nāwaliwali, ka hoʻonaninani, ke ʻole ʻana o ka lehelehe, ka ʻōlelo, ka haʻalulu ʻana o ke kino, ka ʻōpū, palpitations, hypoglycemic coma, nā hopena kūloko o kahi kūloko a me / a ʻano maʻamau, ma ka wahi o ka injection - hypertrophic a atrophic lipodystrophy, kū a me ke kūlohelohe o ka insulin resistance.
No nā hoʻohālikelike no ka hoʻohana ʻana o Novo Nordisk insulin. Nā kūlana hypoglycemic, hypersensitivity i ka lāʻau. Ua kuhikuhi ʻia ka Insulin me ka akahele me nā poʻe maʻi me ka maʻi mellitus me ka maʻi coronary insufficiency a i ʻole impaired cerebral circulation. I kahi kūlana o ka coma o kekahi genesis, nā maʻi ketosis, nā kūlana precomatous, nā maʻi lēʻeha, ka hoʻomākaukau ʻana ma ka hoʻomākaukau ʻana i ka insulin i ka wā o ka mālama ʻana i ka wā maʻi a me ka hāʻawi ʻana i nā maʻi me ka maʻi mellitus.
Nā ʻōlelo kikoʻī. I mea e hōʻemi ai i ka hopena o ka hypoglycemia i ka wā e hoʻoneʻe ana i kahi maʻi i kahi insulin maʻamau, e hoʻemi ʻia ka nui o ka insulin hou. Me nā koi o ka insulin ma lalo o nā papa hana 40, heʻuʻuku ka liʻiliʻi. Inā makemake ʻia nā dosis nui aʻe o ka insulin, e nānā pono i ka mea maʻi e hōʻemi ʻia ka hopena ma o 20% ma ka hoʻomaka ʻana i ka wā e hoʻoneʻe ana i ka mea maʻi mai ka maʻamau maʻamau o ka insulin i ka monocomponent puaʻa. Ke hoʻololi nei i nā ʻano like like ole o ka insulin a i ʻole bovine monocomponent insulin e hele pū me ka hoʻemi ʻia ʻana o ka liʻiliʻi. Ke hoʻoneʻe nei i nā mea maʻi i ka insulin kanaka, ʻaʻole loli i ka hopena inā i paʻi ʻia ka mea maʻi me ka porinine e hoʻomākaukau ai i ka insulin, akā e hoʻoponopono ʻia ia i ka wā e neʻe ana i ka insulin like ʻole a i ʻole insulin bovine. Glucagon, agonists adrenergic, derivatives phenothiazine, salicylates, butadione, glucocorticoids, oral contraceptives, nā lāʻau lapaʻau o ka pūpū moluitary, nā hormone thyroid, nā lāʻau hau, thiazide diuretics, furosemide hoʻonāwaliwali i ka hopena hypoglycemic o insulin, a me nā beta-adrenocide inhibitors. ethyl alkohol, huakaʻi antidiabetic waha - hoʻoikaika. Hoʻonui ka Insulin i ka hopena anti-tuberkulosis o PASK. Ke kāwili nei i ka hoʻomākaukau ʻana i ka hoʻomākaukau o ka insulin me nā insulins hana pōkole, pono e huki mua ʻia ka mea i loko o ka syringe. ʻAʻole ia e kāwili ʻia e hoʻomākaukau i ka hoʻomākaukau ʻana i ka insulin acid-soluble a me nā monocomponent kanaka, me ka mea e pili ana i ka phosphulins-qul-insulin a me nā pēpē-zinc-insulin.
Mea hana NOVO NORDISK, Denemaka.
ʻO ka hoʻohana ʻana i ka lāʻau lapaʻau lā ʻo "Nordisk" hou wale nō e like me ka mea i kuhikuhi ʻia e ke kauka, ʻo nā ʻōkuhi no ka mea pono.
Nā hana
ʻO nā mea kuleana nui o nā ʻoihana: Capital Group Communications (12.4% o nā kālā maʻamau), Novo AS (10,6% o nā waihona maʻamau). ʻO ke poʻo kālā i ka hoʻomaka o Nowemapa 2009 - $ 32.2 biliona.
Luna Hoʻokele o ka Papa Ola - Stan Scheibe (ʻOihana scenibye), ka pelekikena - Lars Fruergaard Jørgensen.
Nā hana hana |Novo Nordisk - Insulin
Mea Hana: Novo Nordisk (Denemaka), Novo Nordisk
Lula: Ryzodeg® Ryzodeg®
ʻAoa: Insulin Degludek a me ka insulin Aspart
Hoʻolaha hana: ʻO ka lālani ke ʻano o ka hana lōʻihi o ka insulin - Degludek a me nā hana hana pōkole - Aspart.
ʻOi aku ka lōʻihi o ka lāʻau lapaʻau ma mua o 24 mau hola.
Nā hōʻailona no ka hoʻohana ʻana: Hoʻomaopopo ʻia ʻo Rysodeg no ka hoʻohana ʻana i ka poʻe me ka maʻi diabetes mellitus type 2 e like me ka monotherapy a i hui pū ʻia me nā lāʻau hoʻoliʻi waha. I ka poʻe me ka maʻi type 1, hoʻohana ʻia ʻo Ryzodeg i ka hui pū me ka insulin ʻaʻa ʻole pōkole a hema paha.
Mea Hana: Novo Nordisk (Denemaka), Novo Nordisk (Denemaka)
Lula: Tresiba®, Tresiba®
ʻAoa: Degludek
Hoʻolaha hana: Hoʻomoe ka lōʻihi i ka hoʻomākaukau ʻana i ka insulin.
ʻO kahi mea hoʻohālike ia o ka insulin kanaka.
ʻO ka hana ʻana o Degludek, ʻo ia ka hoʻonui ʻana i ka hoʻohana ʻana i ka glucose i ka momona o nā momona a me nā ʻiʻo o nā ʻiola, ma hope o ka hoʻopaʻa ʻana o ka insulin i ka poʻe ʻāpana o kēia mau loko. ʻO kāna hana ʻelua e ke neʻe nei i ka hōʻemi ʻana i ka helu o ka hana glucose ma ke akea.
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Mea Hana: Novo Nordisk (Denemaka), Novo Nordisk
Tagu inoa: Novorapid® (insulin aspart), NovoRapid®
Kūkulu: Ma ka 1 ml o ka lāʻau lapaʻau ka: i ka waiwai ikaika: insulin aspart 100 IU, i hana ʻia e ke ʻano o ka biomechnology DNA ʻenehana i kahi kānana o Saccharomyces cerevisiae.
Hoʻolaha hana: ʻO NovoRapid kahi mea hoʻohālikelike o ka insulin kanaka pōkole e hana ana e ka biotechnology DNA recombinant e hoʻohana ana i kahi kānana Saccharomyces cerevisiae kahi i hoʻonui ʻia ai ke hinu waikawa amino ma kahi o ka B28.
Hoʻopili ia me ka mea i loaʻa i ke kaona o ka cytoplasmic o waho o nā pā a hana i kahi mea hoʻonāuki i ka insulin-receptor e hoʻoulu i nā hana intracellular, e komo pū ana me ka helu ʻana o ka nui o nā enzyme nui (hexokinase, pyruvate kinase, glycogen synthetase, etc.).
ʻO ka emi ʻana o ka glucose o ka koko ma muli o ka hoʻonui o kona kaomi intracellular, hoʻonui i ka hoʻonui ʻana i ka iwi, hoʻoulu ʻia i ka lipogenesis, glycogenogenesis, he ʻemi ma ka huina o ka hana glucose i ka ʻāʻulu, etc.
ʻO ka hoʻoneʻeʻana o ka hinu waikawa amino ma ke kūlana B28 me ka waikawa aspartic i ka mākaukau o NovoRapid e hōʻemi i ka uluʻana o nā molekō e hoʻokumu i ka hexamers, kahi i nānā ʻia i loko o ka hopena o ka insulin maʻamau. I kēia mea, ua wikiwiki loa ʻo NovoRapid i ka momona o ka subcutaneous a hoʻomaka ka hana wikiwiki ma mua o ka soluble insulin kanaka.
ʻOi ka NovoRapid e hōʻemi i nā kahe koko nui i nā hola 4 i ka wā maʻa o ka ʻai ma mua o ka soluble insulin kanaka. I ka poʻe maʻi me ka diabetes type mellitus type 1, ʻike ʻia ka nui o ka glucose koko postprandial me ka hoʻokō ʻia o NovoRapid, i hoʻohālikelike ʻia me ka insulin kanaka kīnā.
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Mea Hana: Novo Nordisk (Denemaka), Novo Nordisk
Lula: Levemir®, Levemir®
Tagu inoa: Insulin detemir
Kūkulu: 1 ml o ka lāʻau lapaʻau ka: ʻano waiwai: insulin detemir - 100 PIECES, nā mea waiwai: mannitol, phenol, metacresol, zinc acetate, sodium chloride, disodium phosphate dihydrate, sodium hydroxide, hydrochloric acid, ka wai no ka injection.
Hoʻolaha hana: Hana ʻia ʻo Levemir® e ka biotechnology DNA recombinant me ka hoʻohana ʻana i ka mana Saccharomyces cerevisiae.
ʻO ia kahi mea hoʻonaninani kūloko kūpono o ka hana lōʻihi o ka insulin me ka pākuʻi ʻaoʻao o ka hana.
ʻO ka ʻaoʻao o ka hana a ka lāʻau Levemir Flexpen he nui loa ia ka hoʻohālikelike ʻia i ka isofan-insulin a me ka glargine insulin.
ʻO ka hana lōʻihi o ka lāʻau Levemir ma muli o kahi i hoʻopili pono ʻia ʻana o nā molekina insulin detemir ma ka pūnaewele injection a me ka paʻa ʻana o nā molekōkōkō i nā albumin e ka pūnao me kahi pūnaehana momona momona.
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ʻAoa: Protofan®, Protaphane® HM
Mea Hana: Novo Nordisk (Denemaka), Novo Nordisk
Kūkulu: ʻO 1 ml o ka ʻaina no ka maʻi pūpū e loaʻa ai i ka inika manuolika kanaka 100 IU.
Hoʻolaha hana: ʻO ka insulin hana hoʻopaʻa. Hoʻēmi i ka hoʻoliʻi o ka glucose i loko o ke koko, hoʻonui i kona ʻōhumu ʻana e nā kao, hoʻomaikaʻi i ka lipogenesis a me ka glycogenogenesis, ke kāpili ʻana o ka protein, e hoʻemi ana i ka huina o ka hana glucose i ka ate.
Hoʻopili ʻo ia me kahi kākākia kūikawā ma nā membrane waho o nā pona a hana i kahi mea hoʻonaninani o ka insulin. Ma ka hoʻonoho ʻana i ka synthesis o cAMP (ma nā pūlima momona a me nā pūpū o nā pona) a i ʻole ke komo pololei ʻana i ka pūpuna (nā ʻōpū), ʻo ka mea i hoʻohana ʻia e ka mea i hoʻohana ʻia e insulin mea hoʻouluulu i nā hana intracellular, komo
synthesis o ka helu o nā enzymes koʻikoʻi (hexokinase, pyruvate kinase, glycogen synthetase, etc.).
ʻO ka hoʻohaʻahaʻa o ka glucose i ke koko ma muli o ka hoʻonui ʻana o kāna kaomi intracellular, hoʻonui i ka hoʻihoʻi ʻana a me ka assimilation o nā ʻiʻo, hoʻoulu ʻana i nā lipogenesis, glycogenogenesis, protein synthesis, ka hoʻemi ʻana i ka hōʻemi o ka hana glucose i ka ate (ka hoʻēmi ʻana i ka wāwahi o glycogen), etc.
Tagu inoa: Actrapid HM, Actrapid HM
Mea Hana: Novo Nordisk (Denemaka), Novo Nordisk
Hōʻike:
- Loaʻa ka 1 ml - 40 PIE ANA a 100 PIE ANA.
- ʻO ka waiwai ikaika - kahi waiwai e kūlike me ka insulin kanaka maoli. ʻO kahi kūmole o ke kūlohelohe (pH = 7.0) insulin no ka maʻi (30% amorphous, 70% crystalline).
Hoʻolaha hana: He paa monocomponent hale. ʻO ka lāʻau lapaʻau pōkole: hoʻomaka ka hopena o ka lāʻau ma hope o 30 mau minuke. Loaʻa ka hopena kiʻekiʻe ma waena o mau hola 2.5-5 ma hope o ka hoʻokele ʻana. Hoʻonui ka hopena o ka lāʻau i nā hola 8.
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Mea Hana: Novo Nordisk (Denemaka), Novo Nordisk
ʻAoa: Ultralente MC®, Ultralente MC®
Kūkulu: 1 ml o ka lāleʻa he 40 a 100 mau hui paha. ʻO ka mea ikaika o ka lāʻau lapaʻau ka waiʻawa i ka ʻaina manuahi monocomponent.
Hoʻolaha hana: Nā insulins o ka lōʻihi a lōʻihi hoʻi. ʻO ka hoʻomakaʻana o ka hana he 4 mau hola. ʻO ka hopena kiʻekiʻe loa he 10-30 mau hola. ʻO ka lōʻihi ka hana o 36 mau hola.
Nā hōʻailona no ka hoʻohana ʻana: Dieles mellitus, type I (insulin-depend), diabetes mellitus, type II (non-insulin-depend): kahi kū'ē kū'ē (kū'ē) i ka waha (waha) hypoglycemic (hoʻohaʻahaʻa i ke koko koko) nā lāʻau lapaʻau, ʻāpana kūpaʻa i kēia mau lāʻau (hui pūnaʻi). hoʻōla (hoʻopā i ke ʻano o nā maʻi mellitus maʻi maʻi), nā hana (monotherapy / lapaʻau me ka lāʻau lapaʻau hoʻokahi / a i ʻole ʻo ka hui hoʻohui pū ʻana), ʻo ka hapai (inā he maikaʻi ʻole ka mālama ʻana i ka meaʻai).
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Mea Hana: Novo Nordisk (Denemaka), Novo Nordisk
Lula: Ultratard® HM, Ultratard® HM
Kūkulu: ʻO 1 ml o ka pakanila no ka ʻaina pū me nā mea kūlohelohe kanaka zinc insulin i mea ʻāhu 40 a 100 IU, ma nā pahu wai ml 10 ml.
Hoʻolaha hana: ʻO ka Ultratard HM kahi mākaukau hana hoʻomehana ka lōʻihi. ʻO ka hoʻomaka ʻana o nā hana 4 mau hola ma hope o ke kaʻina subkutan. ʻO ka hopena kiʻekiʻe ma waena o 8 a 24 mau hola. ʻO ka lōʻihi ka hana he 28 mau hola.
Nā hōʻailona no ka hoʻohana ʻana:
- Hoʻopili i kaʻu maʻi diabetes.
- ʻO ka maʻi diabetes mellitus type II: ka pae kūʻē o ka waha hypoglycemic agents, ka pale ʻana i ka paleʻana i kēia mau lāʻau (hui pūnaʻina), nā maʻi kūlohelohe, ka hoʻōla (mono- a i ʻole hoʻohui i nā lāʻau lapaʻau), ʻo ka hapai (inā ʻaʻole maikaʻi ka mālama ʻana i nā meaʻai).
Mea Hana: Novo Nordisk (Denemaka), Novo Nordisk
Kūkulu: 1 ml o ka lāleʻa he 40 a 100 mau hui paha. ʻO ka hana ikaika o ka lāʻau lapaʻau ka waiʻawa i ka hoʻokuʻu ʻana i ka ʻaina pipi nui i hoʻomaʻemaʻe ʻia.
Hoʻolaha hana: Hoʻopaʻa ʻaina Zinc i ka insulin beef beef lōʻihi ʻohala. ʻO ka hoʻomakaʻana o ka hana he 4 mau hola. ʻO ka hopena kiʻekiʻe loa he 10-30 mau hola. ʻO ka lōʻihi ka hana o 36 mau hola.
Nā hōʻailona no ka hoʻohana ʻana: Nā molevlu e hilinaʻi ʻia i ka inaleka, non-insulin-dependence mellitus: ka pae kūʻē (kū'ē) i ka waha hypoglycemic ahente, ka pale ʻana i ka hopena o kēia mau lāʻau. )
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Tagu inoa: Mikstard® 30 NM, Mixtard® 30 HM
Mea Hana: Novo Nordisk (Denemaka), Novo Nordisk
Kūkulu: ʻO ka 1 ml o ka hoʻokuʻuʻana no ka inikeni pūnū - nā mea kūlohelohe kanaka biosynthetic 100 IU (soluble insulin 30% a me ka hoʻōla i ka isofan-insulin he 70%).
Hoʻolaha hana: ʻO Mikstard 30 NM kahi hikiʻole i ka biosynthetic kanaka isofan insulin o ka hana biphasic.
ʻO ka hoʻomaka ʻana o nā hana he 30 mau minuke ma hope o ka mālama subutanutan. Hoʻohou ka hopena kiʻekiʻe ma waena o 2 mau hola a me nā hola 8. ʻO ka lōʻihi o ka hana e hiki i ka 24 hola.
Hoʻomaka ka ʻike o ka hana o ka insulin: ua hilinaʻi ia ma ka ʻano o ka lāʻau o ka lāʻau a hōʻike i nā ʻano kū hoʻokahi.
Mea Hana: Novo Nordisk (Denemaka), Novo Nordisk
Lula: NovoMix®, NovoMix®
Tagu inoa: Nā mapi bulaas Insulin
Kūkulu:
- 1 ml o ka lāʻau lapaʻau i loko:
- mea ikaika: insulin aspart 100 UNITS (1 UNIT e pili ana i ka 35 μg o ka anthdrous insulin aspart),
- nā mea waiwai: mannitol, phenol, metacresol, zinc chloride, sodium chloride, disodium phosphate dihydrate, protamine sulfate, sodium hydroxide, hydrochloric acid, wai no ka injection.
Hoʻolaha hana: ʻO ka lawehala Hypoglycemic, kahi hui o nā mea hoʻonaninani a me ka lōʻihi o ka analogues.
Mea Hana: Novo Nordisk (Denemaka), Novo Nordisk
Lula: Monotard® MC, Monotard® MC
Hoʻolaha hana: ʻO ka insulin wela lōʻihi. Ma hope o ka hoʻolālā subutaneus, hoʻomaka ka hoʻomaka ʻana o nā hana, ma ka awelika, ma hope o 120-150 mau minuke. ʻO ka lōʻihi maʻamau o ka hana he 7-15 mau hola, ʻoi loa ka 24 hola.
Nā hōʻailona no ka hoʻohana ʻana:
ʻO ka maʻi diabetes mellitus type 1 i hui pū ʻia me ka insulin a pōkole a pōkole loa. ʻO ka type 2 diabetes mellitus e koi ana i ka mālama ʻana i ka insulin e hui pū ʻia me nā mea hoʻonā hypoglycemic waha a i ʻole ka monotherapy.
Mea Hana: Novo Nordisk (Denemaka), Novo Nordisk
Lula: Monotard HM®, Monotard® HM
Hoʻolaha hana: ʻO ka Insulin kahi hoʻomehana hana ʻelua o nā kānaka. ʻO ka insulin wela lōʻihi. Ma hope o ka hoʻolālā subutaneus, hoʻomaka ka hoʻomaka ʻana o nā hana, ma ka awelika, ma hope o 120-150 mau minuke. ʻO ka lōʻihi maʻamau o ka hana he 7-15 mau hola, ʻoi loa ka 24 hola.
Nā hana mea hana insulin (Novonordisk)
ʻElua mau maʻi o ka maʻi maʻi, ma kēlā me kēia, ka maʻi o ke ʻano maʻi a me ka lua. Ma ka maʻi ʻaina o ka mea mua, ka maikaʻi o ke ola o ka mea maʻi, a i kekahi manawa o kona lōʻihi, e hilinaʻi pololei ana i ka manawa hoʻokele o ka insulin i loko o ke kino, a me ka mea pono a me ka maikaʻi o ka lāʻau lapaʻau.
ʻAʻole he mea huna e hiki ke hōʻemi ʻia nā lāʻau maikaʻi maikaʻi i ka hoʻōla ʻana o nā antibodies i ke kino o ka mea maʻi, ka mea e hoʻopiʻi i nā kūmole maʻi e hoʻomāhuahua hou aʻe i ke ʻano o ke olakino a hoʻopilikia i ka mālama ʻana.
Ma ka lua o ke ʻano maʻi maʻi, hoʻomaka pinepine ka mālama ʻana i kahi ʻōlelo hoʻolōʻihi e hōʻemi i ka paona a pili pono i ka meaʻai ikaika, e kinai ana i ka ʻai nui o nā mea kāki a me nā meaʻai momona.
Inā ʻaʻohe holomua i ke olakino, kuhikuhi ʻia nā lāʻau lapaʻau i ka hana a ke kuhi ʻana i ka hoʻohiolo ʻana o ke kō.
Inā ʻaʻole kōkua kēia mau kaʻina i ka hoʻokō ʻana i ka hopena i makemake ʻia, ua kuhikuhi ʻia ka insulin.
Hōʻike kēia mau manaʻo āpau ʻaʻole i hoʻokaʻawale ka maʻi diabetes a me ka insulin, a ʻo ka kūleʻa o ke olakino e hilinaʻi nui ʻia i ke ʻano o ka lāʻau lapaʻau, ʻo ia hoʻi, i hoʻoholo ʻia e ka hōʻailona a me ka mea hana.
I ko mākou ʻāina, ua ʻae ʻia ka hoʻohana ʻana i nā lāʻau lapaʻau i hoʻopaʻa ʻia i ka Ministry of Health o ke Lūkini Russian no ka mālama ʻana i ka maʻi diabetes. Ma ke kānāwai, he mau lāʻau lapaʻau kēia o nā mea hana.
No laila, no ka laʻana, ʻo kahi mea hana maikaʻi loa o nā lāʻau lapaʻau i kauoha ʻia no ka maʻi maʻi, me ka nānā ʻole i kona ʻano, me kekahi mau maʻi e pili ana i ka maʻi metabolic, ʻo ia ka hui ʻo Novo Nordisk (Denmark).
Pono e hoʻomanaʻo he alakaʻi ʻo Novonordisk ma waena o nā mea hana i mea hana insulin. He 90 mau ka mōʻaukala o ka ʻoihana: ke hoʻolauleʻa ʻia nei ka hoʻomanaʻo ʻana i ka makahiki 2013 e kū nei. Ua hoʻomaka mua kāna hana me ka hoʻokuʻu ʻana o ka insulin Novonordisk, me ke kōkua o kahi i ola ʻia ai nā miliona miliona o nā maʻi, nā kūlana no ke ola holoʻokoʻa, hana, hana hoʻāno, male male a hānau keiki.
I ko mākou ʻāina, ua ʻike ʻia ʻo Novo Nordisk mai ka hoʻomaka o nā makahiki he kanaono. Eia nō hoʻi, kanaono pākēneka o nā mea maʻi me ka maʻi maʻi ma ko mākou ʻāina e pono ai nā inikini e hoʻohana i nā lāʻau lapaʻau o kēia ʻano inoa, kahi i ʻike ʻia e ka maikaʻi a me ka hilinaʻi, no ka mālama ʻana.
Eia kekahi, ʻike kahi ʻoihana ʻo Novo Nordisk i kahi kahua noiʻi, kahi e hana ai kahi hui o nā kānaka ʻepekema akamai. Ma aneʻi ua hoʻomaka nei ka hoʻokumu ʻana o ka insulin o ke kanaka, a me nā peni pen, i mahalo nui ʻia e nā mea maʻi me ka maʻi mellitus.
ʻO kekahi mea hana i ʻike like ʻia me ka insulin o ka hui ʻo Hoechst (Hoechst AG), i Kelemania a komo i ka hoʻomohala ulu. ʻO kekahi o kāna mau hana o ka hana ʻana i ka lāʻau lapaʻau, me ka mālama ʻana i ka maʻi diabetes, ka mea i hiki ai ke hoʻokaʻawale i kahi ʻoihana i kapa ʻia ʻo Aventis Pharma ma ke ʻano o ka hui Hoechst.
I kēia manawa, ʻike ʻia ka hoʻomākaukau ʻana mai ka hui Aventis Pharma ma ka honua holoʻokoʻa. ʻO nā haneli haneli o nā maʻi e hoʻohana iā lākou i kēlā me kēia lā, e komo pū ana ma ko mākou'āina.
ʻO ia ke kumu i hoʻoholo ai ka hoʻokele o ka ʻoihana e wehe i kāna lālā hana ponoʻī i ko mākou ʻāina a hoʻomaka i ka hoʻokumu ʻana o ka insulin o ke kanaka ma Russia.
I kēia manawa, ʻo ka hui, i kapa ʻia ʻo Sanofi-Aventis Vostok, ua kūleʻa i ka hana a me ka hana ʻana i nā lāʻau lapaʻau i loko o nā cartridges no ka hoʻokō me nā syringes.
Ma ka manawa like ʻole, ʻo ka maikaʻi o nā lāʻau lapaʻau i hoʻoili ʻia ma Lūkia e ʻokoʻa i ka maikaʻi o nā lāʻau like, akā ua hana ʻia ma haole, i hōʻoia ʻia e nā palapala e pili ana i ka Kuhina o ke Ola o ka Lūkini Lūkini.
ʻO kekahi mea hana hoʻomehana insulin i ʻike nui ʻia i ko mākou ʻāina ʻo ia ʻo ʻEli Lilly (USA) i kapa ʻia ʻo "The pharmaceutical buta."
Ma lalo o kēia inoa inoa, ua hoʻohua ʻia nā lāʻau lapaʻau me nā ʻano like ʻole o ka hana, a me nā ʻano ʻano like ʻole.
ʻO keʻano kūikawā, ʻo ka lāʻau lapaʻau, i kapa ʻia ʻo Humulin-N, kahi ʻano ʻenehana kūlohelohe o ke kanaka e kūlike me ka hormone synthesized e ke kanaka olakino.
Hoʻopuka kekahi ʻoihana i nā insulins pōkole a me ka ultrashort, a me nā lāʻau o ka lōʻihi.
Pono e hoʻomaopopo ʻia ma loko o ka mākeke o kā mākou'āina kekahi e hiki ke loaʻa i nā mākaukau o ka brand Eli Lilly, akā hana ʻia i Switzerland. Hoʻomau ʻia kā lākou maikaʻi i kekahi o ka mea kiʻekiʻe loa.
Ma waena o nā mea hana kaulana i ʻike ʻia ʻo ia hoʻi ʻo ka ʻoihana ʻo Brazil ʻo Biobras S / A, ʻo ka hale kūʻai lāʻau lapaʻau mai India Torrent a me ka hui Lūkini ʻo Bryntsalov A, i ʻike pū ʻia i ka poʻe maʻi maʻi i ko mākou ʻāina. Ke hoʻomau nei ia e hoʻohui i nā lāʻau lapaʻau no nā maʻi maʻi i kūʻai ʻia ma nā lāʻau lapaʻau Lūkini e hōʻoia ʻia a paʻa maoli me ko lākou kumu.
Tresiba: ka lōʻihi o ka insulin
No 1.5 mau makahiki me ka maʻi maʻi, ua aʻo wau he nui nā insulins. Akā i waena o ia mea a i ʻole, e kapa ʻia pololei ana lākou, ʻo nā basal, ʻaʻole pono ke koho ʻoiai kekahi: Levemir (mai NovoNordisk) a i ʻole Lantus (mai Sanofi).
Akā ʻo ka mea, i koʻu hele ʻana i kahi haukapila "kamaʻilio", ua haʻi ka endocrinologists iaʻu i kahi mea mana maʻi mosaʻi i ka maʻi diabetes - ke ʻano nui o ka insulin Tresiba mai NovoNordisk, he mea nui loa ia i loaʻa ma Rūsia a ke hōʻike nei wau i ka hoʻohiki nui.
ʻAʻole wau i kūpono, ʻoiai hele mai kahi lāʻau lapaʻau hou. Hōʻoiaʻiʻo nā kauka e hiki i kēia insulin ke hoʻohuli i ka kōpī "kipi" ʻoi loa a hōʻoluʻolu i nā koina kiʻekiʻe, e hoʻololi ana i ke pakuhi i ka mākaʻikaʻi mai ka sinusoid kūʻiʻo i kahi laina kūpono.
ʻOiaʻiʻo, ua holo koke wau e hoʻopaʻa i ka pilikia ma ka hoʻohana ʻana iā Google a me nā kauka aʻu i ʻike ai. No laila kēia ʻatikala e pili ana insulin lōʻihi lōʻihi basal Treshiba.
ʻO nā makahiki i hala iho nei ua hōʻailona ʻia e kahi lāʻau lapaʻau lāʻau no ka hoʻomohala ʻana i nā insulins lōʻihi, mākaukau e pīpī ʻia ma ka podium ke alakaʻi ʻole ʻole o ka honua ʻoi aku ka maikaʻi loa mai Sanofi. E noʻonoʻo wale no i ka makahiki o hoʻokahi makahiki Lākusa helu helu hoʻokahi i loko o ka umauma insulin basal.
ʻO nā mea pāʻani ʻē aʻe ma ke kula ʻaʻole i ʻae ʻia no ka pale o ka lāʻau hoʻomake. Ua kau ʻia ka lā palena mua o ka make me ka 2015, akā ua loaʻa iā Sanofi i kahi deferment a hiki i ka hopena o 2016 ma ka pau ʻana o ka ʻikepili hui ʻana me Eli Lilly no ka kuleana kūʻokoʻa e hoʻopuka nona iho, nā mea kikoʻī ʻokoʻa o Lantus.
ʻO nā hui ʻē aʻe i helu ʻia i nā lā a pau i ka mana o ka paten e hoʻomaka ana i ka mana e hoʻomaka i ka ulu ʻana o ka uluʻana. Ua ʻōlelo nā poʻe hōʻike, i ka wā e hiki mai ana, e loli nui ka mākeke no ka insulin lōʻihi. E kū hou mai nā lāʻau a me nā mea hana hou, a pono nā mea maʻi e hoʻoponopono i kēia. Ma kēia hiʻohiʻona, ʻike ʻia ka puka o waho o Tresiba.
Ano, e kaua kaua maoli ma waena o Lantus a me Tresiba, ʻoiai ke noʻonoʻo nei ʻoe e kūʻai hou ʻia ka huahana hou.
ʻO ka hana ikaika o Treshiba ʻo ia pili ʻia. ^ E Ha yM. Loaʻa ka hana ultra-lōʻihi o ka lāʻau lapaʻau ke hoʻomaikaʻi i ka waiko hexadecandioic, ʻo ia kekahi o ia mea, e ʻae ana i ka hoʻokumu ʻana o nā multihexamers kūleʻa.
Hoʻokumu lākou i ka layer subcutaneous i kapa ʻia nā mea i kapa ʻia depot insulin, a me ka hoʻokuʻu i ka insulin i ka ʻōnaehana ʻōnaehana i ka like me ka holo mau, me ka piʻi ʻole o ka haʻi, de facto ʻano o nā insulins basal ʻē aʻe. I mea e wehewehe i kēia kaʻina hana pharmacological paʻakikī i ka mea hoʻohana maʻamau (ʻo ia hoʻi, iā mākou), hoʻohana ka mea hana i kahi mea hoʻohālike.
Ma ka pūnaewele pūnaewele ʻike maka ʻoe i ka hoʻokomo ʻana i kahi kaula o nā pou, kahi o nā bead he nui i ka hexamer, ka mea ma hope o kekahi, me ka manawa like ʻole o ka manawa e wehe ai mai ka waihona. ʻO ka hana a Treshiba, e hoʻokuʻu ana i nā like me "nā ʻāpana" manuahi "mai kona depot, e like me ke ʻano like, e hāʻawi nei i ka kaila mau o nā lāʻau lapaʻau i loko o ke koko.
ʻO kēia ka hana i hāʻawi i ka lepo i nā mea hōʻeuʻeu Treshiba i hoʻohālikelike ʻia e ia me kahi pākī a i ʻole me ka insulin akamai. ʻO kaʻoiaʻiʻo, ʻaʻole eʻoi aku kēia mau ʻōlelo ma mua o ka hoʻonui nui.
Hoʻomaka ka Tresiba hana ma hope o 30-90 mau minuke a hana a hala i nā hola 42. ^ E Ha yM. ʻOiai ʻo ka hoʻonani maikaʻi loa i haʻi ʻia i ka lōʻihi o ka hana, pono e hoʻohana ʻia ʻo Treshib I ka lā hoʻokahi, e like me Lantus kahiko loa.
Nui ka poʻe maʻi e nīnau ma kahi i ka mana o ka lā o ka insulin i ka hala o 24 mau hola, inā paha i haʻalele ai ka lāʻau i hope o kāna mau "ʻili" a pehea e pili ai i ka mana ākea. ʻAʻole ʻike ʻia kēlā mau ʻōlelo i loko o nā mea ʻala ma Tresib.
Akā wehewehe mai nā kauka, ma ke ʻano he kānāwai, ua nui ka maʻi o ka poʻe maʻi iā Tresib i hoʻohālikelike ʻia iā Lantus, no laila ua hoʻemi nui ʻia ka hala ma luna.
Me nā hana kūpono, hoʻomaʻamaʻa maikaʻi ʻia ka lāʻau lapaʻau a nani hoʻi, no laila, ʻaʻohe pono e kamaʻilio e pili ana i kekahi helu helu o nā "ʻili."
ʻO ka hiʻohiʻona nui o Treshiba loa ʻōlelo pākuhi ʻano, flat profile. ^ E Ha yM. Hoʻohana ʻia ʻo ia i "paʻa i ka lāʻau paʻa" ʻaʻole ia e waiho i wahi no nā manu.
Ma ka ʻōlelo ʻōlelo lapaʻau, ʻano ʻano like ʻole i ka hana o ka lāʻau lapaʻau ʻano ʻano.
No laila ma ke ʻano o nā hoʻokolohua lapaʻau i ʻike ʻia aia ka loli o Treshiba he 4 mau manawa haʻahaʻa ma mua o Lantus.
| Kēlā manawa o ko lākou kūwaho ʻana i nā lā 3-4 |
I ka hoʻomakaʻana o ka hoʻohana ʻana o Treciba, pono e koho pololei i ka dute. Lalo i kekahi manawa. Me ka wai kūpono, ma hope o nā lā 3-4 mau lā i hoʻopaʻa ʻia kahi insulin "wili" a i ʻole waiwai kūlike ("Ke kūlana kūlike"), ka mea e hāʻawi i kahi kūʻokoʻa i nā hua o ka manawa e hoʻolauna ai iā Treshiba. Ua hōʻoia ka mea hana e hiki ke lawelawe ʻia i ka lāʻau i nā manawa like ʻole o ka lā, ʻaʻole kēia e pili i kona pono a me ka hana o ka hana. Eia naʻe, ke kuhikuhi nei nā kauka e pili ana i ka hana paʻa a me ka lawelawe ʻana i ka lāʻau lapaʻau i ka manawa like a i ʻole e hilahila ai i ka hoʻoponopono uʻi lūlū a ʻaʻole hoʻi e hoʻokaʻawale i ka "state equilibrium".
Tresiba a i ʻole Lantus?
Ke aʻo ʻana e pili ana i ka mana kupaianaha o Treshiba, ua hoʻomaka koke wau i kahi endocrinologist maʻamau me nā nīnau. Ua makemake wau i ka mea nui: inā maikaʻi loa ka lāʻau, no ke aha e ʻole ai ka poʻe a pau e loli? A inā he ʻano pololei, ʻo wai ka mea e pono ai ʻo Levemir? Akā nā mea āpau, e huli ʻia, ʻaʻole maʻalahi.
ʻAʻohe mea ia e ʻōlelo ai ua loaʻa nā kānaka i ka maʻi o kā lākou maʻi. I ka ʻike mau nei o ka ʻōlelo. Hoʻolaha nā mea āpau a ʻaʻohe mea i hoʻomākaukau ʻia i nā hopena mua loa. ʻO ka ʻōlelo koʻikoʻi no ka loiloi ʻana i ka hopena o ka "pani ʻana i ka insulin" ʻo ia ka uku. No kekahi mau keiki, ʻo kahi maʻi hoʻokahi o Levemir i kēlā me kēia lā ua lawa ia no ka uku uku (ʻoi! Aia kekahi).
ʻO ka poʻe i pau ʻole me ka Levemire pālua ka mea maʻamau e māʻona me Lantus. A ʻike nui kekahi iā Lantus mai kahi makahiki.
Ma keʻano holoʻokoʻa, ʻo ka hoʻoholo e kuhikuhi i kēia a i ʻole hana ʻia ka insulin e ka kauka hele mai, ka mea nāna e nānā i kāu mau pono a me nā ʻano me ka kumu hoʻokahi o ka hoʻokō ʻana i nā kōlei maikaʻi.
| ʻO ka hakakā ʻana o ka insulin ma waena o Sanofi a me Novo Nordisk. Kelihi lōʻihi lōʻihi |
ʻO ka mea hoʻokūkū koʻikoʻi o Treshiba, ʻo ia a ʻo Lantus. Pono ia i kahi hoʻoponopono hoʻokahi a ʻike ʻia no ka hana lōʻihi a hoʻomau. Hoʻohālikelike nā haʻawina hoʻokūkū ma waena o Lantus a me Tresiba e like me ka mālama pono ʻana i nā lāʻau like me ke ʻano o ka mana o ka background glycemic. Eia naʻe, ua hōʻike ʻia ʻelua mauʻokoʻa nui. Ke mua pākē Hōʻike ʻia ʻo insulin ma Tresib hoemi ʻia e 20-30%. ^ E Ha yM. ʻO ia, i ka wā e hiki mai ana, ke manaʻo ʻia mai kekahi o nā pono waiwai, akā i ke kumukūʻai o ke aniani hou, ʻaʻole pono kēia. Kahua ka helu o ka nogturnal hypoglycemia i emi ma ka 30%. ^ E Ha yM. Ua lilo kēia hopena i lilo i alakaʻi koʻikoʻi o Treshiba. ʻO ka moʻolelo o nā mea pani i ka hilo i ka pō he pōkole o kekahi maʻi maʻi, no ka mea i ka pau ʻole ʻana o kahi ʻōnaehana mau. No laila, ʻo ka ʻōlelo hoʻohiki e hōʻoia i kahi hiamoe kuʻikahi e nānā maoli.
Kuhi ʻia aku ʻo Tresiba ma nā peni syringe me kahi pahu pahu o 300 E. Pack of 5 ʻringlelo penikala e pili ana ke kumukuai 8 000 r. ^ E Ha yM. ʻO ia hoʻi, hiki i ke kumukūʻai o kēlā me kēia peni nā 1600 p. Lākusa Ka mea i huli iā 2 mau manawa maʻalahi. ʻO nā kumukūʻai like like me ia 3500 r
Ma kahi o ka hoʻokō 'ana i ka hana kūpono, he ala lōʻihi loa kekahi lāʻau lapaʻau hou e kūkulu i kahi loea ʻoihana e pili ana i ka hoʻolaha ʻana i ka hana ākea.
ʻO ka ʻike e pili ana i ka ʻike o ka hoʻohana ʻana iā Treshiba i kekahi mau ʻāina i hōʻiliʻili iki e ka mea: nā kānaka lapaʻau e mālama i nā lāʻau lapaʻau e loiloi ana i ko lākou maʻi āpau.
I Kelemānia, no ka laʻana, hoʻonāukiuki iā Tresib i hoʻokumu ʻia.
ʻO ka hui kūʻokoʻa kaKelemaniaHale KūʻainoKaukaʻikaʻiaLoaʻai lokoOlakinoMālama (Ke Alemania Kelemania no ka Pono a me ka Pono i ka mālama mālama olakino) i mālama i kāna iho noiʻi ʻana, hoʻohālikelike i ka hana a Tresiba me kāna poʻe hoʻokūkū, a hiki mai i ka hopena ʻaʻole hiki i ka insulin hou ke kaena aku i kekahi mau pōmaikaʻi nui («ʻaʻoleʻaua hoʻohui ʻiawaiwai») Hoʻolaha maʻalahi, no ke aha e uku ai i kekahi mau manawa hou aku no ka lāʻau lapaʻau ʻaʻole ʻoi aku ka maikaʻi ma mua o ka Lantus kahiko maikaʻi? Aka, ʻaʻole wale ia. Ua ʻike ʻia nā poʻe loea Kelemania nā hopena ʻaoʻao mai ka hoʻohana ʻana i ka lāʻau lapaʻau, naʻe naʻe i nā kaikamahine. ^ E Ha yM. Ua ʻike ʻia lākou ma 15 mai nā 100 mau kaikamahine e lawe iā Treshiba no 52 mau pule. Me nā lāʻau lapaʻau ʻē aʻe, ʻo ka hopena o nā hōʻeha he 5 mau manawa ma ka liʻiliʻi.
I ka laulā nui, i ko mākou ola maʻi hānai, ua ulu ka hopena o ka hoʻololi ʻana i ka insulin basal. Ke ulu a nui ke keiki a kū a me ka maʻi diabetes me Levemir, e palapu ka pilina a mākou. No laila, ke pili nei kēia mau manaolana iā Lantus a i ʻole Tresiba. Manaʻo wau e neʻeneʻe kāua: e hoʻomaka mākou me ka maikaʻi maikaʻi, a ma laila e ʻike ai mākou. E mālama no wau i nā mea a pau i makemake i ka papa hana. A paha pū me ka ikaika me ka holomua ʻepekema! Māhele e hoʻokaʻawale no kā mākou hele ʻana i Tresiba 'atikala.
ʻO ka insulin hana lōʻihi
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Ka inoa: Protaphane® HM Mea hana - Novo-Nordisk (Denmark) Kaʻahele: 1 ml o ke kaʻa hoʻoluhi no ka maʻi ʻaina i ʻike ʻia i ka inika manuahi pūnū 100 IU. Hana i ka lāʻau lapaʻau: Hoʻomakeke i ka hoʻomākaukau ʻana i ka insulin minamina. Hoʻemi ia i ka hoʻoliʻiliʻi o ka glucose i ke koko, hoʻonui i kona kōpili ʻana e nā kiko, hoʻomaikaʻi i ka lipogenesis a me glycogenogenesis, synthes ...
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Ka hana hana - Eli-Lilly (USA) Composition: ʻApana hāpau o 30% amorphous a me 70% crystalline i loko o ke kanaka, ʻaina zinc suspension, pH = 6.9–7.5 Hoʻo hana Pharmacological: Insulin (kanaka) (Insulin (kanaka). ka lōʻihi o ka hana i ka insulin Ma hope o ke kaina ʻana o ka s / c hoʻomaka e hana ma hope o 4 mau hola, i loaʻa ka hopena kiʻekiʻe loa ...
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Mea hana - Novo-Nordisk (Denmark) Hōʻike: 1 ml o ka lāʻau lapaʻau he 40 a 100 mau ʻāpana paha. ʻO ka mea ikaika o ka lāʻau lapaʻau ka waiʻawa i ka ʻaina manuahi monocomponent. Hapa-hana lāʻau lapaʻau: Insulins of long and superlong action. ʻO ka hoʻomakaʻana o ka hana he 4 mau hola. ʻO ka hopena kiʻekiʻe loa he 10-30 mau hola. Duration ...
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Mea hana: Novo-Nordisk (Danemaka) Kaʻaina: 1 ml o ke kaʻaahi no ka maʻi ʻona he mau biosynthetic kanaka zinc-insulin crystalline 40 a 100 IU paha, ma nā pahu wai ml 10 ml. Ke hana lāʻau lapaʻau: ʻO ka Ultratard HM kahi mākaukau lōʻihi me ka insulin. ʻO ka hoʻomakaʻana o nā hana 4 mau hola ma hope o ke kaʻina subutanutan ....
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Mea hana - Indar ZAO (Ukraine) Mea waiwai: Kaʻai puaʻa. ʻO ka hoʻokuʻuʻana o ka insulin porcine - 70% crystalline zinc-insulin a me 30% insulin amorphous. Nā hana lāʻau lapaʻau: lōʻihi ka hana insulin. ʻO ka hoʻomaka ʻana o ka hana ma hope o nā hola 1-1.5. ʻO ka hoʻomaka ʻana o ka hopena lōʻihi loa ma hope o nā hola 5-7. ʻO ka lōʻihi o ka hana he 24 ...
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Mea hana - Indar ZAO (Ukraine) Nā meaʻono: Poc monocomponent insulin. ʻO 100% kaila manuahi e kulu. Hana i ka lāʻau lapaʻau: ka lōʻihi o ka hana o ka insulin. ʻO ka hoʻomaka ʻana o ka hana ma hope o nā hola 8-10. ʻO ka hoʻomaka ʻana o ka hopena kūpono loa ma hope o nā hola 12-18. ʻO ka lōʻihi o ka hana e pili ana i nā hola 30-36. Nā hōʻailona: Diabetes mellitus. Ke ala ...
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Mea hana - ICN GALENIKA (Yugoslavia) Mea waiwai: Porcine insulin-zinc monocomponent crystalline suspension. Hapa-hana lāʻau lapaʻau: Insulins of long and superlong action. Hoʻomaka ka hana i nā hola 1-2 ma hope o ka hoʻokele ʻana, ka hopena ka hopena ma hope o nā hola 8-24, ʻo ka lōʻihi o 28 mau hola. Nā ʻōhua no ka hoʻohana ʻana: ...
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ʻAha inoa: ʻApina ʻaina zulin. Ka hana hanahana - Tarkhominsky Pharmaceutical Plant Polfa (Polani) Hoʻohui: Mākaukau i ka hoʻomaʻemaʻe ʻana i ka insulin porcine lōʻihi e hana nei i ka chromatographically. 1 pahu me 10 ml o ka ʻaina paʻa i ka insulin 400 a 800 mau ʻāpana. Hapa-hana i ka lāʻau lapaʻau: Hoʻomoe lōʻihi i ka hoʻomaʻemaʻe ʻana i ka porinine porinine e hoʻomaʻemaʻe loa ʻia. ʻO ka hoʻomakaʻana o ka hana ...
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Ka hana hanahana - Tarkhominsky Pharmaceutical Plant Polfa (Polani) Hoʻohui: Mākaukau i ka hoʻomaʻemaʻe ʻana i ka insulin porcine lōʻihi e hana nei i ka chromatographically. 1 pahu me 10 ml o ka ʻaina paʻa i ka insulin 400 a 800 mau ʻāpana. Nā hana lāʻau lapaʻau: lōʻihi ka hana insulin. ʻO ka hoʻomaka ʻana o nā hana he 1.5-3 mau hola, lōʻihi loa he 12-1 mau hola, lōʻihi 24-30 ...
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Mea hana - Novo-Nordisk (Denmark) Hōʻike: 1 ml o ka lāʻau lapaʻau he 40 a 100 mau ʻāpana paha. ʻO ka hana ikaika o ka lāʻau lapaʻau ka waiʻawa i ka hoʻokuʻu ʻana i ka ʻaina pipi nui i hoʻomaʻemaʻe ʻia. Ke hana lāʻau lapaʻau: Zinc suspension of most pure long-acting beef insulin. ʻO ka hoʻomakaʻana o ka hana he 4 mau hola. ʻO ka hopena kiʻekiʻe loa he 10-30 mau hola ....
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Kauka kuhikuhi
Actrapid NM kaulana loa i ka mālama ʻana i ka maʻi maʻi. Loaʻa ia i nā waiwai hypoglycemic ikaika a kūpono i ka mālama ʻana o ka maʻi type a me ka type 2.
Ua hoʻohana pinepine ʻia kēia insulin i ka lāʻau lapaʻau a ʻike ʻia ʻole ʻole ʻole. Ke kaomi nei ʻo ia i nā ʻenehana hou hou aku. Akā pili mau kā Actrapid NM a paʻa i kona kūlana.
ʻO ka mea hana mea ʻoihana ʻo Denmark ʻo Novo Nordisk A / S.
Apidra he hana ia na ka hui Kelemania ʻo Sanofi-Aventis. ʻO ka inoa inoa honua he insulin glulisin. ʻO Glulisin insulin ka mea nui e hana ai i Apidra. Hoʻopili like kēia insulin me nā mea a me nā meaʻala i ke kanaka kūlohelohe. Ua hōʻike ʻia ka lāʻau lapaʻau iho i ka mālama ʻana i ka maʻi diabetes i nā pākeke a me nā keiki ma mua o 6 mau makahiki.
ʻO ka hui Lūkini OJSC Pharmstandard e hana i kēia insulin ma ke ʻano o kahi hopena no ka maʻi.
Biosulin P he hana manuahi manu pōkole e loaʻa ana, me ka ʻenehana recombinant DNA.
Hāʻawi hoemi glucose i loko o ke koko, e hoʻonui ana i kona huakaʻi intracellular, hoʻemi ʻana i ka helu o ka hana glucose i ka ate, ka hoʻomaikaʻi ʻana i ka paʻi ʻana o nā glucose i nā kiko, hoʻoulu a lipogenesis.
Insulin Lantus (Lantus) he hanauna hou o ka insulin. No kona nohona pōkole loa, ua lanakila ʻo ia i ke aloha o nā maʻi maʻi maʻi. He hana ia na ka hui Kelemania Sanofi-Aventis. ʻO kahi lāʻau lapaʻau maikaʻi no ka mālamaʻana i nā maʻi maʻi type 1 a ma kekahi mau mea, ka maʻi diabetes type 2.
Insulin levemir He kāne lōʻihi loa ia o ka insulin, paʻa ia no 12-24 hola. ʻO ka mea hana i ka insulin, ʻo ke kamupene ʻo Novo Nordics, e hoʻolaha i kēlā me kēia lā, i kahi kokoke ʻole i ke kaʻina hana o kāna lāʻau. Ma ka hoʻomaʻamaʻa, hoʻokau ʻia kēlā me nā hiʻohiʻona pilikino o ke kino.
Me nā maʻi papa ʻaina 2, hiki i ke kua i makemake ʻia a hiki i kahi lā, a me ke ʻano lāʻau papa lāʻau 1, pono ʻoe e hana ʻelua i ka lā.
Loaʻa kēia insulin mau mau pono.
NovoRapid Flexpen he hana ia o ka hui ʻo Danish ʻo Novo Nordisk A / S. He lāʻau lapaʻau hou kēia i ka mālamaʻana i ka maʻi diabetes type 1 a me ke ʻano. No ka poʻe maʻi me ka lua o ka maʻi maʻi, ua kuhikuhi ʻia i ka wā ʻaʻole i loaʻa ka hopena kūpono i nā papa haʻahaʻa i ke kō.
Protafan NM he hana ia o ka hui ʻo Danish ʻo Novo Nordisk A / S. ʻO kēia kahi monocomponent biosynthetic kanaka isofan-insulin suspension a medium Duration. Ua hoʻohana ʻia no ka wa lōʻihi o ka mālama ʻana i ka maʻi maʻi. Hiki ke kapa ʻia ʻo Protafan NM kahi hoʻolālā waho. Akā hoʻomau lākou i ka mālama ʻana, a ua kaulana loa i waena o nā maʻi maʻi.
Humawai he mea i kūlike mai ia me ka inika ke kanaka. Hoʻohana ʻia ka lāʻau lapaʻau e hoʻoponopono i nā kiʻekiʻe o ka glucose koko. ʻO kāna mea hana nui ka insulin lispro. Loaʻa i nā pahu pahu, ka nui 3 ml. Hoʻokumu kekahi o nā mea hana i ka lāʻau i ke ʻano o nā penikala syringe mākaukau. Mai nā analogue, hiki ke hoʻokaʻawale ʻia nā Humalog Mix 25 a me 50.
Humulin NPH He lāʻau kaulana ia i ka mālama ʻana i ka maʻi diabetes i ka wā lōʻihi. ʻAʻole hiki ke hoʻopili ʻia ka hoʻomohala hou.
Akā ma muli o kona kūlana kiʻekiʻe, hoʻomau ia e ʻoliʻoli i nā mea kiʻekiʻe. Nā ʻāina ʻē aʻe i hana i ka lāʻau lapaʻau: India, Farani, Rusia me ka launa pū ʻana me Farani.
ʻO ka mea hana nui ʻo ka hui Farani ʻo Eli Lilly.
Humulin Kūʻai he hana i ka hui Farani "Eli Lilly". Ua hōʻike mua ʻia kēia lāʻau lapaʻau he wahi maikaʻi i ka mālama ʻana i ka maʻi maʻi. Ua kuhikuhi ʻia kēia insulin no ka maʻi mellitus type 1 a i ʻole type 2 diabetes mellitus, i ka manawa kūpono ʻole ka meaʻai a me nā lāʻau lapaʻau. ʻO Humulin Regular ka hana maʻamau o ka insulin.
ʻO ka insulin i hana ʻia i loko o Rūsia: ʻano
I kēia manawa ma Rūsia he 10 miliona mau kānaka i maʻi me ka maʻi maʻi. ʻO kēia maʻi, me ʻoe i ʻike ai, i pili pū i ka hoʻonāukiuki ʻana o ka hoʻokumu ʻana o ka inika i nā ʻāpana o nā pancreas, nāna nō i kuleana no ka metabolism i loko o ke kino.
I mea e noho holo ai ka mea maʻi, pono ʻo ia e hoʻokomo pinepine iā i kēlā me kēia lā i kēlā me kēia lā.
I kēia mau lā ke ʻano he ʻoi aku ma mua o ka 90 ka nui o nā lāʻau lapaʻau i hana ʻia ma nā mākeke huahana kūlohelohe - pili pū kekahi i ka insulin.
Eia naʻe, i kēia lā ua alo ka ʻāina i ka hana o ke ʻano ʻana i ka nui o nā lāʻau lapaʻau nui. No kēia kumu, ke hana nei kēia lā i nā hana āpau e hōʻoia i ka lilo ʻana i ka insulin i mea e hoʻohālike i nā hoʻokolohua kaulana i ka honua nei i hana ʻia.
Hoʻokuʻu i ka insulin insulin
Ua hōʻike ka World Health Organization i nā ʻāina me nā lehulehu e ʻoi aku ana ma kahi o 50 miliona mau kānaka i ka hoʻonohonoho ponoʻī i kā lākou hana ponoʻī o ka insulin a i ʻole ka poʻe maʻi i nā pilikia me ka loaʻa ʻana o ka hormone.
I kēia mau makahiki i hala iho nei, ʻo ke alakaʻi i ka hoʻomohalaʻana o nā lāʻau ʻenehana genetically i loko o ka mokuʻāina ʻo Geropharm.
ʻO ia wale nō, ʻo ia wale nō ma Rūsia, e hana ana i nā insulins o ka home i ke ʻano o nā mea a me nā lāʻau. I kēia manawa, ua hana pōkole ʻo Rinsulin R a me nā hana laser Rinsulin NPH e hana ʻia ma ʻaneʻi.
Eia nō naʻe, ʻae ʻia, ʻaʻole e pau ka hana ʻana ma laila. Ma ka pili me ke kūlana kālai'āina o ka'āina a me ka hoʻokau ʻana o ka hoʻopaʻi i nā poʻe hana haole, ua kauoha ʻo Pelekikena Vladimir Putin iā Rusikirin i ka holomua ʻana o ka hana hana insulin a hana i kahi hoʻopaʻa o nā ʻoihana ʻenehana.
E hoʻololi i ka lālani Rūkia i nā lāʻau lapaʻau ʻē aʻe
Wahi a nā loiloi loiloi, i kēia manawa ʻaʻole ʻo ka mea hoʻokūkū o Rusia i ka mākeke honua no ka hoʻolālā ʻana o insulin. ʻO nā mea hana nui he ʻekolu mau hui nui - ʻo Eli-Lilly, Sanofi a me Novo Nordisk. Eia naʻe, ʻoi aku ma mua o 15 makahiki, hiki i ka insulin hūloli ke hoʻololi i kahi e pili ana i 30-40 pakeneka o ka nui o ka nui o ka hormone i kūʻai aku ʻia ma ka'āina.
ʻO ka ʻoiaʻiʻo loa ua hoʻonohonoho ka ʻaoʻao o ka Lūkini i ka hana o ka hāʻawi ʻana i ka ʻāina i kahi me ia ponoʻī o ka insulin, e hoʻololi hou i nā lāʻau i nā haole i hana ʻia e ka ʻāina ʻē.
Hoʻomaka hou ʻia ka hana ʻana o ka hāmeʻa i nā manawa Soviet, akā laila, ua hoʻohua ʻia ka wae ʻana o nā holoholona mai nā holoholona, ʻaʻohe maikaʻi o ka hoʻomaʻemaʻe kiʻekiʻe.
I nā makahiki 90, ua hana ʻia kahi hoʻāʻo e hoʻonohonoho i ka hana o ka inikua genetic home, akā ua hoʻohālikelike ʻia ke ʻāina i nā pilikia kālā, a ua oki ʻia ka manaʻo.
I kēia mau makahiki āpau, ua hoʻāʻo ʻo Lūkini e hana i nā ʻano like like ʻole o ka insulin, akā ua hoʻohana ʻia nā huahana haole he mea waiwai. I kēia lā, ua hoʻomaka ka hoʻonohonoho ʻana i nā huahana e hoʻokuʻu i kahi huahana kūloko. ʻO kekahi o lākou kā Geropharm hui i hōʻike ʻia ma luna.
- Ua hoʻolālā ʻia ma hope o ke kūkulu ʻana i kahi mea kanu i ka māhele o Moscow, e hana ka ʻāina i kēia mau ʻano o nā lāʻau lapaʻau hou no nā maʻi maʻi maʻi, i ka mea hiki ke hoʻokūkū me nā ʻenehana o Komohana. Hōʻike nā mana o nā mea hou a me ka mea kanu kahiko e hana i ka 650 kg o ka waiwai o ka makahiki hoʻokahi.
- E hoʻokuʻu ʻia ka hana hou i ka 2017. I kēia hihia, ʻoi aku ka uku o ka insulin ma mua o kona mau hoa ʻē aʻe i waho. E hoʻopau ʻia kēlā polokalamu i nā pilikia he nui i ke kahua o ka maʻi maʻi o ka ʻāina, a me nā kuleana kālā.
- ʻO ka mea mua, e hoʻokomo nā mea hana i ka hana o ka ultrashort hormone a me ka hana lōʻihi. I ka hana o ʻehā mau makahiki, e hoʻokuʻu ʻia kahi laina piha o nā kūlana ʻehā. E hua ʻia nā Insulin i loko o nā hue, pahu pahu kūwele, hoʻoheheʻe ʻia a hoʻohana hou ʻia i nā penikala syringe hou.
Inā paha he mea maoli nō ia e ʻike ʻia ma hope o ke kaʻina hana a puka mai nā loiloi mua o nā lāʻau lapaʻau hou.
He aha ke ʻano o ka hene o ka hana ʻenehana?
ʻO ka hopena kūpono a ʻaʻole i invasive no ka maʻi maʻi ma ke ʻano he ʻano ponoʻenehana kūloko, kahi e kū pono ai i ke ʻano o ka physiological i ka hormone kumu.
No ka hoʻāʻo ʻana i ka maikaʻi a me ka maikaʻi o ka Rinsulin Rinsulin R a me ka hana 'ana i ka insulin Rinsulin NPH, kahi hana ʻepekema i hana ʻia e hōʻike ana i kahi hopena maikaʻi o ka hoʻohaʻahaʻa i ka glucose o ke koko i ka poʻe maʻi a me ka loaʻa ʻole o kahi ʻano alika i ka wā o ka mālama lōʻihi me nā lāʻau lapaʻau a Russia.
Eia kekahi, hiki ke kahakaha he mea e pono ai i nā poʻe maʻi e ʻike pehea e loaʻa ai kahi paila insulin manuahi, i kēia lā he mea nui loa kēia ʻike.
ʻO ka haʻawina e komo ai i nā maʻi maʻi 25 he 25-58 mau makahiki, ka mea i hōʻike ʻia me ka maʻi maʻi maʻi type 1. Ma nā mea maʻi 21, ua nānā ʻia kahi ʻano maʻi nui loa. Loaʻa i kēlā me kēia lā i ka nui o ka dosis pono o ka Lūkini a me nā insulin ʻē aʻe.
- ʻO ka like o ka glycemia a me ka gogemae hemoglobin i loko o ke koko o nā mea maʻi i ka wā e hoʻohana ana i ka ʻōnaehana ʻikepili i ka noho ma kahi o ka pae e like me ka wā o ka hoʻohana ʻana i ka hormone o ka hana haole.
- ʻAʻole hoʻi i loli.
- I loko o nā lā kūikawā, ʻaʻole i mālama ʻia ka ketoacidosis, kahi ʻano kūlohelohe, kahi hōʻeha o ka hypoglycemia.
- ʻO ka dosis nui o kēlā me kēia lā i ka wā o ka nānā ʻana i mālama ʻia i loko o ka mauʻu like me ka manawa maʻamau.
Eia kekahi, ua hana ʻia kahi noiʻi e loiloi i ka hana pono o ke hoʻohaʻahaʻa ʻana i ke kūleʻa o ke koko me ka hoʻohana ʻana i nā lāʻau ma Rinsulin R a me Rinsulin NPH. ʻAʻole i ʻokoʻa nā ʻokoʻa āpau i ka wā e hoʻohana ai i ka inikua o ke kūkulu ʻāina a me nā hana o waho.
No laila, ua hele mai nā kānaka ʻepekema i hiki ke hoʻohuli ʻia ka maʻi diabetes i nā ʻano like ʻole o ka insulin i ʻole nā hopena. I kēia hihia, ʻo ka mālama ʻana a me ke ʻano o ka hoʻokele ʻana o ka hormone mālama.
Ka hoʻohana ʻana o Rinsulin NPH
ʻO kēia hormone he lōʻihi ka hana o ka hana. Hoʻopili koke ʻia ia i loko o ke kahe wai, a e hilinaʻi ka nui o ka uku, ke ʻano a me nā mahele o ka hoʻokele o ka hormone. Ma hope o ka lawelaweʻana i ka lāʻau, hoʻomaka ia i kāna hana i kahi hola a i ka hapa.
ʻO ka hopena maikaʻi loa e nānā ʻia ma waena o 4 a me 12 mau hola ma hope o ke komo ʻana i ke kino. ʻO ka lōʻihi o ka hoʻonuiʻana i ke kino he 24 mau hola. He keʻokeʻo ke kaʻaalo ʻana, he ʻāpana ʻē aʻe ka wai.
Ua kuhikuhi ʻia ka lāʻau lapaʻau no ka mellitus maʻi o ka ʻano a me ka lua, ua ʻōlelo pū ʻia no ka wahine me nā maʻi i ka wā hāpai.
Pākuʻi ʻia nā maʻi:
- Ke aloha ʻole kūʻokoʻa o ka lāʻau i kekahi ʻāpana o ka ʻāpana o ka insulin,
- ʻO ka heleʻana o ka hypoglycemia.
ʻOiai ʻaʻole hiki i ka hormone ke komo i ka pāʻai placental, i ka wā hāpai aʻa ʻaʻohe paʻa o ka hoʻohana ʻana i ka lāʻau.
I ka wā o ka umauma, ʻike ʻia ka hoʻohana ʻana i ka hormone, eia naʻe, ma hope o ka hānau keiki pono nō e nānā i ke pae o ka glucose i ke koko a, inā pono, hoʻohaʻahaʻa i ka nui.
Hoʻokomo ʻia ka Insulin. Ua kuhikuhi ʻia ke ʻano e ke kauka, ma muli o ka hihia kūikawā o ka maʻi. ʻO ka awelika o kēlā me kēia lā he 0.5-1 IU i pākeke o ka paona.
Hiki ke hoʻohana ʻia ka lāʻau lapaʻau me ka hana kūʻokoʻa a hui pū ʻia me Rinsulin R.
Ma mua o kou komo ʻana i ka insulin, pono ʻoe e hoʻopio i ka pahu pahu ma lalo o ʻumi mau manawa ma waena o nā pāma, i mea e lilo ai ka hapanui. Inā i hana ʻia ka pahuhopu, hiki ʻole ke hoʻohana i ka lāʻau lapaʻau, ʻoiai ke alakaʻi nei i ka hewa ʻole. Eia pū kekahi, ʻaʻole hiki iā ʻoe ke hoʻohana i ka hormone inā loaʻa nā mea haole a me nā lipi i hoʻopili ʻia i nā paia.
Hiki ke hoʻomākaukau ʻia kahi mākaukau e mālama ʻia ma ka mahana o 15-25 mau kekona no 28 mau lā mai ka lā o ka wehe. He mea nui ia e mālama ʻia ka insulin mai ka lā a me ke wela wela.
Me ka overdose, ulu ulu ka hypoglycemia. Inā hoʻohaʻahaʻa ka hōʻemi o ka glucose i ke koko, hiki ke hoʻopau ʻia kahi hanana hikiʻole ke hoʻokaʻawale i nā meaʻai momona i loaʻa ka nui o nā kīhai. Inā hōʻeha nā hihia o ka hypoglycemia, ke mālama ʻia kahi hopena glucose 40% i ka mea maʻi.
I nā insulin Physiological a hoʻopaʻa ʻia
I ka hana maʻamau o ke kanaka, hōʻiliʻili ka ate i ka glucose i ka wā ʻai, i ka wā e hoʻokuʻu ʻia ai ka insulin e ka pancreas e pale ai i ka hyperglycemia. I ka paneʻana i ka glucagon, hoʻokuʻuʻia nā hale glucose i loko o ke kino e pale ai i ka hypoglycemia. ʻAʻole hiki ke noʻonoʻo ʻia kēia mau palupima koʻikoʻi i ka hoʻohana ʻana i ka insulin injectable, no ka mea, ua paʻa kēia ʻaina i ka ʻōpū a me ka momona a ʻaʻole i hiki i ka ate.
ʻAʻohe o nā ʻōpū o nā glucagon, no laila, e hoʻihoʻi pono i ka ʻaihue hiki i ka hana o ka ate ma ka hoʻokuʻu ʻana i ka glucose e kū i ka hypoglycemia.
Ma waho o ka hoʻoponopono ʻole o ka pae o ka glucose i loko o ka ate, ʻoi aku ka paʻakikī o ka mālama ʻana i ke kiʻekiʻe o ka glucose i ke koko. Kōkua a wikiwiki hou a lōʻihi. ʻO nā peni a me ka nānā ʻana i nā ʻōnaehana i maʻalahi e mālama iā ia iho. Eia nō naʻe, pololei ka nānā ʻana i ka hana ate e hoʻohiki e hāʻawi i nā hopena maikaʻi loa no ka poʻe me ka maʻi diabetes type 1.
Ke hoʻohana nei iā Rinsulin P
ʻO kēia lāʻau lapaʻau ka hana pōkole hana. I ka hiʻohiʻona, ua like ia me Rinsulin NPH. Hiki ke lawelawe ʻia i ka subcutaneously, a me ka intramuscularly a me ka hana 'ana ma lalo o ka mākaʻikaʻi paʻa o kekahi kauka. Pono ke ʻae ʻia ka dosage me ke kauka.
Ma hope o ka komo ʻana o ka hormone i ke kino, hoʻomaka ka hana i ka hapalua hola. Loaʻa ka loiloi kiʻekiʻe ma ka manawa o nā hola 1-3. ʻO ka lōʻihi o ka hoʻonuiʻana i ke kino he 8 mau hola.
Hoʻokomo ʻia ka Insulin ma ka hapalua hola ma mua o kahi pāʻina a i kī kīmaha māmā me kekahi nui o nā huama. Inā hoʻohana ʻia hoʻokahi lāʻau lapaʻau no ka maʻi maʻi, e mālama ʻia ʻo Rinsulin P ʻekolu mau manawa i ka lā, inā pono, hiki ke hoʻonui ʻia ka dosage i ʻeono manawa i ka lā.
Ua hōʻike ʻia ka lāʻau lapaʻau no ka mellitus maʻi o ka ʻano mua a me ka lua, i ka wā hāpai, a me ka hoʻēmi ʻana no ka pakanui kalepa o ka pākia ʻaina me ke ʻano he pilikia. ʻO ka Contraindications kekahi intolerance pilikino i ka lāʻau, a me ka mua o ka hypoglycemia.
Ke hoʻohana nei i ka insulin, he hopena alerine, hōʻeha ʻia ka ʻili, hiki ke loli, a me ka loaʻa pinepine - hoʻolilo anaphylactic.
He aha nā hana a Diasome e hana ai?
Hoʻopili ka Diasome nanotechnology i nā paʻa ikaika me nā pauku o ka insulin e pale ai i ka komo ʻana o ka insulin e nā ʻōpū a me nā momona a hoʻoneʻe i kēia insulin e komo i ka ate, kahi e hiki ai iā ia ke mālama i ka hana pilikino maʻamau.
ʻAʻole molohi kēia mau mea ikaika i ka hana o ka insulin a ʻaʻole e hōʻemi i ka lōʻihi o ka hana. I ka mea ʻoiaʻiʻo, ua hōʻike nā haʻawina mua i ʻoi aku ka nui o ka insulin e komo i ka puʻuwai e hoʻomaikaʻi i ka hopena mua a hoʻolioli i ka manawa ma ka laha
Ua hoʻomohala ka hui i ka nanotechnology - kahi waiwai, me ka hoʻohui ʻana i ka insulin, e like me ka organelle intracellular liʻiliʻi i kuhikuhi ʻia i ka ate.
He kūʻokoʻa ʻo Nanotechnology o ke ʻano o ka insulin a hiki ke hoʻonui i ka palekana a me ka pono o nā ʻano āpau. Mahalo i kēia, e loaʻa i kēlā me kēia maʻi ka manawa e hoʻihoʻi i ka hana maoli o ke ake i ka mālama glucose. Pili kēia i ka basul a bolus insulins i paʻi ʻia me ka syringe pen a i kahi pākaʻi paha.
Wahi a ka hui, hoʻokipa ʻia lākou e Diasom me ka hana like me nā mea hana o insulin e like me Novo Nordisk a me Eli Lilly, no laila ua hoʻokomo ʻia ka additive i loko o ka insulin i ka hana hana.
ʻOiai ke loaʻa nei kēia hoʻomohala i kahi ʻano e hiki ai i nā lāʻau lapaʻau a me nā maʻi ke hoʻopili iā lākou iho i ka lāʻau.
ʻImi ʻikepili
Ua hele ka huahana ma ke kahua mua, hōʻoia paʻa. Ke hoʻolilo nei ka hui i nā mea komo no ka pae 2. V. Blair Gekho, MD, ka luna noiʻi nui ma Diasome, i wehewehe ʻo ka noiʻi ʻana i ka noiʻi ana i ka kuhikuhi dosage. Kahi ʻia ke ʻano e pili ana i ka ʻike hoʻopiʻi loiloi hou mai ka pae 2 a me ka pae 2b.
ʻO ka lua o ka hana e hiki ke hoʻokele i ka pae o ke kūmole insulin basal-bolus e hoʻohana ai i ka ʻenehana hou. E nānā pū ka ʻoihana i ka hopena o ka hoʻohui i ka hoʻomaikaʻiʻana i nā hōʻailona hoʻomohala diabetes, me ka kiʻekiʻe o ka nui o ka hemoglobin glycated, ka ulu ʻana o hypoglycemia, a me ka pono o ka bolus a me ka insulin basal. Ma ka pili ʻana i hoʻopili ʻia nā mea maʻi pākē me ka maʻi type o ka maʻi 1, kahi ma nā pae o GH ma waena o 6.5% a me 8.5. % Makemake ʻo Diasome e hoʻopaʻa inoa e pili ana i kanaono mau poʻe e komo i ka manawa o ʻekolu mau hana o ka mālama maʻamau, a laila aia hou ʻia ʻekolu mahina me ka insulin i hoʻohui ʻia me nā ʻano like ʻole o ka insulin lōʻihi.
Ua ʻōlelo ʻo Douglas Machmore, MD, ka loea o ka ʻenehana no Diasome: "Ma ke ʻano he nui o ka hoʻomohala ʻana o ka holomua o ka naʻau o ka insulin, e hoʻomau mākou i ka wahi e loaʻa ai ka insulin ma hope o ka inikua no ka mea nui o ka hana o ka puʻuwai ma kā ka metabolism . ^ E Ha yM.
Hoʻolālā nā Diasome e hoʻomaka i ka hōʻike 3 ma ka hoʻomaka ʻana o 2020 a, inā ke ʻae ʻia, manaʻo ia e 2022 ka mea e kū i ka mākeke.
He aha nā mea hana ʻē aʻe?
ʻO kahi hoʻomohala diasome ʻaʻohe o kekahi ʻano. No ka laʻana, hoʻāʻo ʻo Eli Lilly e hoʻomohala i nā huahana me ka palena ʻole o ka absorption i ka pā adipose a me ka uaua. Ua haʻalele ʻo Eli Lilly i kā lākou hoʻāʻo ʻana e hoʻomohala i ka insulin hou i ka wā i hōʻike ai nā hoʻokolohua lapaʻau i ʻike ʻole ʻia ka pehu a me nā enzyme.
ʻAʻole ka loli o Diasome i ke kumu maʻamau o ka insulin. Ma kahi o lākou, ke hoʻāʻo nei lākou e hoʻoikaika i ka pilina ma waena o nā molika insulin e kau iho ana. ʻO kēia ala hoʻokalakala ʻole ʻoi aku ka mea i loaʻa ai ka huahana me nā pilikia ʻole o ka pehu.
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Ka uku o ka maʻi diabetes: he aha ia mea i uku ʻia a uku ʻia no ka maʻi diabetes, nā ʻāpana
ʻO ka maʻi mellitus kuʻi ʻole i ʻike ʻole ʻia: he aha ia, nā pae uku i ka wā e hiki ai i ka mea maʻi e loaʻa ana i ka maʻi kō i loko o ke kino i ka pae e pono ai, e manaʻoʻiʻo ʻia ua uku ʻia ka pathology. ... -
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