Formin: nā ʻōlelo a me nā loiloi, ke kumukūʻai o nā papa

Aia ʻo Metformin i ka papa o ka biguanides, ka hopena hypoglycemic i hoʻokumu ʻia ma ke kahe ʻana o ka kūlohelohe o ka pale kino a ka nui, a me ka hoʻonui i ka hū o ka glucose e nā momona a me nā puʻuwai. Mālama i ka lāʻau i ke komo ʻana o ka glucose i loko o ka ʻōpū, hoʻopaʻa ʻia ka gluconeogenesis, hoʻopaʻa i ka metabolidoma lipid. He hopena maikaʻi hoʻi ka Metformin ma luna o nā moku koko, e pale ai i nā hōʻeha o ka vascular i ka maʻi maʻi.

ʻAʻole hōʻeuʻeu ka lāʻau lapaʻau i nā cell beta i ka hana ʻana o ka insulin, no laila palekana ia e pili ana i ka hiki ʻana o hypoglycemia.

Ma hope o ka lawelawe ʻana, hoʻomohala ka hopena therapeutic ma hope o 2 mau hola, ʻo ka lōʻihi o ka lōʻihi o ka hana.

Hōʻike ʻia ka lāʻau lapaʻau no ka mālama ʻana o ke ʻano maʻi type 2, ka mea nui paʻakikī paʻakikī, i ka haʻalele ʻana o ka meaʻai a me ka hana.

Nā Hoʻohui

• hoʻohālikelike i ka lactic acidosis (hōʻiliʻili i nā lactic acid tissues)
• ketoacidosis
• maʻi diabetes type 1
• hapai
• nā makahiki o nā keiki
• hypoglycemia a me ka maʻi diabetes
• nā pēpē koʻikoʻi a me kaʻeha o kaʻeha
• ka ʻaloʻakā maʻi
• maʻi decompensated maʻi maʻi
• haaheo.

ʻO ka hapa a me ke ʻano o ka hoʻokele ʻana

Hoʻonohonoho paʻa ʻia ka dosage, ma ke ʻano he glycemia a me ka glycosuria.

ʻO ka helu mua o ka formin he 850 mg / lā. I loko o ke mau hebedoma he ʻelua, ʻoi aku ka hoʻonui ʻana o ka nui a hiki i ka hoʻokō ʻana i kahi mana glycemic paʻa. Ka papa mālama mālama - 2 mau papa / lā.

ʻO ka uku no kēlā me kēia lā he 3 mau papa.

ʻO ka nui o kahi lāʻau ma mua o 1 mau papa e pono e hoʻokaʻawale i ʻelua pota. Lawe i ka lāʻau lapaʻau ma a ma hope o ka ʻai ʻana. Ke lawe ʻia ma mua o kahi kīʻaha, e hoʻolōʻihi ʻia ka manawa e hoʻokō ai i kahi hopena therapeutic.

No ka poʻe maʻi ma hope o 60 mau makahiki a me nā pilikia hōʻino koʻikoʻi, hoʻonui i ka dosage me ka makaʻala.

Nā hopena hopena

• lactic acidosis (me ka palupalu o ka palaka a a ʻole ka hana a ka lolo, ke inu waipiro, decompensation cardiovascular)
• hypoglycemia
• nā hopena ʻeha o ka gastrointestinal: anorexia, ʻeha, ʻōpū, ka ʻono metallic, ʻeha o ka ʻōpū (hele i ka hoʻomaka ʻana o ka mālama ʻana a me nā piʻi ʻana o ka nui o ka make)
• malabsorption o ka waiama B12 a me B9
• dermatitis allergic.

Hoʻonohonoho ʻia ka formin no ka monotherapy a i hui pū ʻia me sulfonylurea a i ʻole insulin. Hoʻolaha ʻia ka hana hoʻohui me ka insulin i loko o kahi haukapila a hiki i ka hoʻomāliʻiliʻi ke hoʻopaʻa ʻia e pale ai i ka hoʻomohala ʻana o ka hypoglycemia.

I ka wā o ka formin therapy, pono e kāohi i ka pae o ka serum creatinine i hoʻokahi manawa i kēlā me kēia mahina ʻeono, a hoʻokahi manawa i ka makahiki e nānā i ke koko no ka pae o ka vitamin B12.

I ka hoʻomaʻamaʻa ʻana me ka formin, ʻike nui ʻole ka ʻawaʻawa.

Ka hana like ʻole o formin me ka lāʻau lapaʻau no ka mālama ʻana i nā maʻi concomitant e hiki ai ke hoʻonui a hoʻonāwaliwali i kāna hopena hypoglycemic. No laila, ʻo ka hoʻomohala ʻana i nā lāʻau like ʻole e ʻona ʻia e ka neʻe i ke kauka, e noʻonoʻo ana i ka pilina o nā mea lapaʻau.

Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau

ʻOiaʻiʻo, aneane pinepine kēlā mau mea maʻi e aʻo i nā ʻōlelo aʻo mai ka mea hana ma mua o ka hoʻohana ʻana i ka lāʻau. A eia ka hoʻoholo kūpono. ʻOiaʻiʻo, ma kēia hihia wale nō e hiki ke hoʻoholo no ka mea pono i nā hopena kūpono paha e hiki ke hele mai ma muli o ka hoʻokō pono ʻana o ka lāʻau lapaʻau, me ke ʻano o ka hopena o ke kino a me ka hopena maikaʻi mai ka hoʻohana mau ʻana o ka lāʻau lapaʻau.

E hoʻomaka me nā mea pono, e hoʻomaopopo i ka hūnā ʻia o ka lāʻau ma ke ʻano o nā papa. Aia he ʻokoʻa nā pā he kanakolu papa, a aia nō i loko o ia mau mea he kanaono.

Ua hōʻike ʻia ka hopena pharmacological koʻikoʻi a Formin Pliva ma hope o ka hoʻohana mau ʻia ʻana, hiki ke kūpono i ka hoʻemi ʻana i ka pae o ka glucose i loko o ke koko o ka mea maʻi. Eia nō naʻe, ua ʻōlelo ʻia e lawe pololei ia i kēlā mau mea maʻi e kūʻokoʻa ana i ka insulin, ʻo ia hoʻi, ka poʻe i ʻike ʻole i ka insulin.

Hiki ke loaʻa kēia waiwai kūpono ma muli o ka mea nui e hoʻonui i ka hoʻohana kūpono i ka hoʻohana ʻana i nā glucose. Ma muli o ka hopena, ua hoʻokaʻawale ʻia nā kaʻina āpau o nā gluconeogenesis e loaʻa ana i loko o ka ate. ʻO ka helu o ke pā ʻana o nā huehue maʻa mau e kū nei i ka digestive tract o kekahi kanaka ke hoʻemi nui ʻia nō hoʻi.

ʻO kekahi hiʻohiʻona maikaʻi e hoʻokaʻawale i Formin Pliva ʻo ia ka mea i kōkua me ka hoʻonui ʻana i ka naʻau o nā ʻāpana kino a pau i ka insulin. ʻO ia ke kumu, hiki ke hoʻohaʻahaʻa pono i ka pae o ka glucose i ke koko o ka mea maʻi.

ʻOiaʻiʻo, inā mākou e kamaʻilio e pili ana i ka mea hiki ke hoʻonui i ke kaʻina hana o ka insulin i ke kino ma muli o ka hoʻohana mau ʻana i ka lāʻau lapaʻau, a laila ma kēia hihia ke ʻano o ka hopena.

Akā i ʻike ʻia ma hope o ka lawe ʻana iā Formin, he emi iho ka nui o ka triglycerides i loko o ke koko o ka mea maʻi, a me ka hoʻohaʻahaʻa ʻana i ka pae o ka coagulability o ka mea i haʻi ʻia.

Lawe ʻia ka lāʻau lapaʻau i loko, ʻo ka piʻi ʻana o ka waiwai nui o ka hana nui i ke kino e loaʻa ai i ʻelua mau hola ma hope o ka hoʻokō ʻana. Akā ʻo kona hele ʻana hope loa i loko o ke koko e hala ma hope o ʻeono mau hola.

Hoʻokuʻu ʻia ia mai ka mea maʻi ma o ka lolo.

I ka manawa e hoʻomaka ai e lawe i ka lāʻau lapaʻau?

Ua ʻōlelo ʻia ma luna nei he mea kūpono ia e hoʻomaka i kahi lāʻau lapaʻau ma hope o ka kūkā mua ʻana me kāu kauka. ʻAʻole hiki iā ʻoe ke hoʻomaka i kahi mālama kūʻokoʻa me kēia lāʻau lapaʻau.

ʻO ka maʻamau, ma kahi pūʻulu o nā maʻi e hōʻike ʻia no ka Formin Pliva, ua ʻike ʻia kēlā mau mea maʻi me ka maʻi diabetes type 2.

A ma ka maʻamau ʻo kēia mau poʻe nā maʻi i ʻike i nā pilikia me ka hoʻolalelale ʻana, me ka poʻe hoʻi i lawe ʻole i ka insulin ma o nā injections.

Akā he mea nui hoʻi e hoʻomanaʻo i ka Formin pliva i nā ʻaoʻao maikaʻi ʻole. Ua contectedicated ma kēia hihia:

• i ka mea maʻi i ka ketoacidosis maʻi maʻi a i ʻole comic coma,
• ua hiki nō hoʻi ke ʻeha ka maʻi i nā maʻi o nā maʻi like ʻole, a me ke ʻano, ma muli o ke ʻano o ka maʻi i nā inikua.
• ua komo pū ka contraindications me nā pilikia ʻike ʻole i ka hana o ka puʻuwai, a me nā hopena āpau o nā maʻi o kēia kino,
• ʻaʻole pono ʻoe e lawe i ka lāʻau lapaʻau i ka wā hāpai a i ka manawa ua hāpai ʻia ka wahine.
• a he mea pono, i ka manawa e ʻokiʻoki ʻia kekahi kanaka i nā ʻāpana o ka ʻākena.

Hōʻike nā loiloi o nā mea maʻi he nui nui ke hahai i kahi meaʻai kūikawā i ka wā e mālama ai me kēia lāʻau lapaʻau.

Pono e liʻiliʻi ia o nā kalori a hāʻawi i ke kau pohō kūpono o ka mea maʻi. A koi ʻia nō hoʻi kēia e nā loea loea.

He aha nā helu analogs a me kā lākou kumukūʻai?

E like me nā lāʻau ʻē aʻe, ua hoʻohālikelike ʻo Formin Pliva. Aia ke kumukūʻai ko kā lākou kumukūʻai ma ka lima o ka mea hana, ʻo ia hoʻi, kahi ʻano hana i hana ai kēia mau lāʻau. Inā mākou e kamaʻilio e pili ana i ka mea kēia he loea therapeutic honua, a laila e uku ʻia kona kumukūʻai, kēlā me kēia manawa i nā manawa kiʻekiʻe ma mua o ka mea hoʻohālike Lūkia.

I kekahi hihia, ma mua o ka hoʻomaka ʻana i ka mālama ʻana no ka maʻi ma lalo, pono ʻoe e ʻōlelo mau i kāu kauka. Pono ʻoe e ʻike mai iā ia nā hopena kūpono e puka mai i kahi lāʻau lapaʻau kūikawā, a me nā mea contraindications e hoʻohana ana no kona hoʻohana. He mea nui ia e nānā i kahi hoʻokolohua piha a ma hope wale iho o ka hoʻomaka ʻana o ka mālama ʻana me Formin Pliva, nā ʻōlelo aʻo no ka hoʻohana ʻana i ka lāʻau lapaʻau e wehewehe i nā mea e hoʻohana ʻia ai ka lāʻau lapaʻau, a ma nā wahi like.

I kekahi manawa ma ka hoʻomaka ʻana o ka maʻi mai ka papa hana o ka kūwili ʻana, hiki paha i kekahi mau leʻaleʻa. Hōʻike kēia i ke ʻano o ka nausea a i ʻole ka luaʻi. Hiki pū kekahi i ka hoʻohaʻahaʻa ʻana a me ka ʻono ʻē aʻe i loko o ka waha.

Ke hōʻike nei kekahi mau maʻi i ka holo ʻeha me ka maʻi diabetes. ʻO kaʻoiaʻiʻo, inā inu ʻoe i ka lāʻau lapaʻau ma nā inika kiʻekiʻe loa, a laila hiki i nā hopena olakino maikaʻi aʻe ke hōʻeha.

Inā mākou e kamaʻilio e pili ana i nā analogues e kaulana loa i kēia lā, a laila, laʻa, no nā māka he nui i hiki iā lākou ke kuhikuhi iā Bagomet, e hoʻomaka ana kona kumukūʻai mai ka 130 a hiki i ka 220 rubles i kēlā me kēia pākaha, e like me ka helu o nā papa i loko. Hoʻopilikia ʻia ke kumukūʻai e ka neʻe ʻana o ka waiwai nui, no ka laʻana, kahi ʻāpana he kanaono mau haneli o 850 mg ua manaʻo ʻia he 220 mau rubles, akā ʻo ka like o ka papa āpau o 1000 mg ua loaʻa ke kumu kūʻai ma mua o eha mau rubles.

Aia kekahi analogue e like me Glycon. Mālama ʻia kona kumukūʻai i ka neʻe ʻana o ka mea nui a me ka helu o nā papa. Loaʻa ia mai 115 a 280 mau rubles. ʻO ka ʻāina o kēia hana i kēia mau paila, e like me ka wā ma mua, ʻo ʻAmelika kekahi.

Akā ʻo ia e like me ia, ʻaʻole pono ʻoe e hoʻololi kūʻokoʻa i ka lāʻau i ʻōlelo ʻia e kou kauka, inā ʻaʻole ʻoe e ʻeha wale i kou olakino.

Ke wehewehe nei ke wikiō ma kēia ʻatikala pehea e lawe pololei ai iā Formin a me nā peni ʻē aʻe.

Lapaʻau lāʻau

Ma hope o ka hoʻokele ʻana, lawe ʻia ka waiwai nui mai ka gastrointestinal tract. Hiki i ka bioavailability ke 60%. ʻO ka ʻike plasma nui loa e nānā ʻia ma hope o 2 mau hola.

HELAI! Hoʻopili ke komoʻana me ka meaʻai i ka nui o ka loaʻa ʻana o ka lāʻau lapaʻau ma 40%, ʻo ka hopena therapeutic piha e 35 mau minuke ma hope iho.

Kāohi i nā ʻili koko ʻulaʻula, ʻaʻole i paʻa i nā protein plasma. Hoʻomaʻamaʻa ʻia ka Cumulation ma nā io ʻiʻo, nā pēpē a me nā ʻōpū o ke kino, me nā kinipoki salivary.

ʻO ka hapalua hapa-ola ʻo 6.5 hola.

Hoʻohana ia no ka type 2 diabetes mellitus, kahi i hōʻike ʻia e kahi makemake i nā kūlana ketoacidotic. ʻO ke kumu no ke koho ʻana i ka lāʻau i loko o ka nele o ka meaʻai.

Nā hopena hopena

• gastrointestinal tract: kūwaha ka maʻi dyspeptic (nausea, luaʻi, ka ʻōpū o ka ʻōpū, ʻeha o ka ʻōpū), huehue, lemulewa, nele i ka momona,
• endocrine system: hoʻohaʻahaʻa i nā pae haʻahaʻa glucose,
• metabolism: kakū lactic acid, vitamin B ka nele₁₂,
• hematopoietic ʻōnaehana: megaloblastic type anemia,
• ʻili: rashes, ʻeha.

Ke keu

• ninini
• utuka
• nā ninia
• ho'ēmi i ke ʻano kino
• ʻeha ka ʻōpū
• myalgia
• wikiwiki hanu
• āhāhuʻe
• nalowale o ka ike ana
• hoʻomohala ʻana o kahi coma.

Hoʻokomo pū ʻia nā mea lapaʻau:

• ʻO ka hoʻopau ʻia ʻana o nā mea hana hypoglycemic,
• hale hoʻomaha i loko o kahi hale hoʻokipa,
• hemodialysis
• hoʻomanawanui ʻano.

Hoʻohui nūhou

Hiki ke hoʻomohala ʻia ka hopena o ka hopena me ka hoʻohana pono ʻana o Formin a me nā ʻano ʻē aʻe. No laila:

• ʻO nā derivatives sulfonylurea (Butamide, Glibenclamide), salicylates (Aspirin, Salicylamide), acarbose, non-steroidal anti-inflammatory (Nimesil, Ketorol), monoaminoxygenase inhibitors (Selegiline, Nialamide), oxytetracycline azolefin cyclophenyltin cyclophenyltin cyclophenyllinin encyclopedia. (Anaprilin, Concor) hoʻonui i ka hopena o ke kala i ke kumu o ka mea nui,
• glucocorticosteroids (Beclomethasone, Methylprednisolone), contraceptives oral (Regulon, Novinet), glucagon, analogues hormone tiroid (Thyroxine, Thyroidin), thiazide (Indapamide, Chlortiazidium, Efuroteminazidazum, Furoseminazide, Efurotazida Aminazine), ka waikū nikotinic (Cordiamin, Acipimox) e hōʻemi i ka hopena hypoglycemic,
• hoʻonui ka hapedipine i ka hoʻopili ʻana, ka ʻike nui loa i loko o ke kaila, e pale i ka hoʻopuka ʻana o ka mea hana,
• lohi ʻo cimetidine i ka lawe ʻana o ka metformin, ka hopena i ka hoʻonui nui o ka acidosis lactic,
• nā lāʻau lapaʻau cationic (Digoxin, Morphine, Vancomycin) me ka hoʻohana lōʻihi hiki ke hoʻonui i nā ʻike o Metformin i ke koko ma o 60%,
• nā nā anticoagulants e hoʻonāukiuki i nā hana o nā hana i hope,
• Ua komo nā yodine e hoʻohālikelike i ka hōʻiliʻili ʻana o ka waihona nui o Formin me ka hoʻomohala ʻana i ka hoʻomehana lactic acidosis.

Nā ʻōlelo kikoʻī

I ka hoʻomaʻamaʻa ʻana me ka lāʻau lapaʻau e pono:

• kaohi ʻana o ka hana kidney
• e hoʻoholo i ka ʻikeʻana o ka lactate i loko o ke koko koko ʻelua i kēlā me kēia makahiki,
• nānā i ka nānāʻana o ka glucose i ka wā e hui pū me ka insulin, sulfonylurea derivatives.

HELAI! ʻO nā hōʻiliʻili o ke kaʻa holoʻokoʻa, nā hōʻeha, nā umauma ākea, nā maʻi ākea a me nā maʻi i hōʻeha ʻia me ke piʻi ʻana o ke ea - ʻo ia mau mea kēia ka hōʻailona no ka hoʻopau ʻana o Formin me ka koho hou ʻana o ka insulin.

Hōʻike ʻia i ke au kahiko

Hiki ke kuhikuhi i nā kānaka ma mua o 65 mau makahiki o lalo o ka mālama pono ʻana, me ka noʻonoʻo ʻana i ka loiloi o ka hopena therapeutic hopena a me nā hopena ʻino loa. Pono kēia mau mea maʻi e hoʻoholo i ka hoʻoilo ma lalo o ka wā e hoʻomaka ai ka mālama ʻana (ʻaʻole ʻike ʻia nā helu creatinine koko no ka loiloi ʻana i ka hana o ka keiki).

Hoʻohālikelike me nā kikowaena

Aia nā lāʻau lapaʻau e like me ka hana hoʻokūkū like:

1. Vipidia. ʻO ka mea momona ka alogliptin. Hoʻopilikia i ka synthesis o ka insulin i ka pancreas, hiki i ka bioavailability 100%. Ua papaia ia me ke kuapo mellitus type 1. E hoʻohana me ka mālama aka ma mua o ka pancreatitis, i hui pū me ka insulin a me ka sulfonylureas. ʻO 25 mg ka helu i kēlā me kēia lā. Hoʻomaopopo ʻia me ka meaʻai ʻole, me ka ʻū ʻole ʻana, me ka inu ʻole wai. ʻAʻole i ʻike ʻia kahi pilina me nā lāʻau lapaʻau ʻē aʻe.
2. ʻO Glibenclamide. ʻO ka mea waiwai he glibenclamide. He mea hoʻoulu ia i ka synthesis o ka insulin e nā ʻenau islet Langerhans. Hoʻonui ʻo ia i ka ʻike ʻana i nā kiko o ke kino i ka insulin, kōkua e hōʻemi i ka lipoproteins, loaʻa kahi hopena antithrombotic. Hoʻopili ʻia i ka hana o ka pāhaʻi, hoʻoneʻe ʻia e ka ʻōpū o ke ake, i hoʻopā ʻia e nā keiki. Hoʻopili maikaʻi ia i nā kahe koko. Hoʻonohonoho ʻia ka pākēkē i kēlā me kēia ma muli o ka paʻakikī o ke ʻano o ka maʻi maʻi a me ka makahiki o ka mea maʻi.
3. Miglitol. Hoʻopili i ka enzyme alpha-glucosidase ma ka epithelium o ka pūpū liʻiliʻi. Mālama i ka wāʻa o ka polysaccharides i ka glucose, e hoʻemi ana i kona komo ʻana. Aneane ʻaʻole pili i nā hui koko koko, ʻaʻole i loli ka haku excretion. Lā ʻia ka lāʻau lapaʻau no ka hoʻohana ʻana me colitis ulcerative, ka hiki ʻana o ka hernias nui. Pono ia i lawe ʻia a ma hope o ka ʻai.
4. Avandia ʻO ka mea waiwai e rosiglitazone. Hoʻonui i ka ʻike pono ʻana o ka kiko adipose i ka insulin, nā mākala palupalu, nā kino ʻili. Hoʻokomo ia i ka metabolism, hōʻemi i ka hoʻoliʻi o ka glucose, insulin, nā momona momona i loko o ke kahe. Hoʻopili ia i nā ʻōnaehana koko i ke kiʻekiʻe kiʻekiʻe, ʻaʻole ia e hilinaʻi i ka neʻe ʻana o ka lāʻau a me nā makahiki o ka mea maʻi. Kuhi ʻia e nā keiki. Hoʻohana ʻia ia e like me ka insulin. Contraindicated i ka maʻi coronary syndrome, pani ʻole. Hoʻolahalaha ʻia ka lawe ʻia ʻana ma kahi o ka pili ʻana o ka meaʻai.
5. Starlix. ʻO ka mea nui ka nateglinide. Kōkua i ka hoʻihoʻi ʻana i ka hoʻomaka mua o ka hana ʻana o ka insulin, e hoʻonui i kona kiʻekiʻe i nā minuke 15 mua ma hope o ka ʻai ʻana, ma muli o ke ʻano o ka holi ʻana o ka glucose. Hōʻike ʻia ka kiʻi ʻia he hapalua hola ma mua o ka papaʻai 3 mau manawa i ka lā. E hoʻohana me ka akahele ʻana i ka hana koʻikoʻi o ka pūpū a me nā pēpē. Hiki ke hoʻohanaʻia e like me ka monotherapy.

Ludmila: “Ua maʻi koʻu ʻohana pili i ka maʻi maʻi i nā makahiki i hala aku nei. Mai ia manawa, ua lawe ʻo ia i nā lāʻau lapaʻau, kekahi o Formin. Ma mua, ua hiki ke kō i ke kō. 18 A laila hoʻomaka ka mālama ʻana. Kōkua anei ʻo Formine? ʻAe, a mahalo nui ʻia. Lawe ka hoahānau i nā lāʻau lapaʻau āpau e like me ka mea i ʻōlelo ʻia, ʻaʻole hopohopo e ʻike i kā lākou mau hōʻailona glucose. A paʻa mau ia i ka pae o 5-6. "

Olga: “Ua maʻi koʻu maʻi kuʻuna.ʻOluʻolu wau e loaʻa ʻole iaʻu nei, ʻoiai ke kau mau ana ka momona a me ke kō i loko o ka maʻamau maʻamau. Akā i ka lua o ka hapalua, ua maʻi ka maʻi gestational, ma hope o ka hoʻohālikelike ʻana i ka hānau keiki. Ua kākau iaʻu ʻo ka endocrinologist iā Formin. Kahi mea maikaʻi e kōkua ana e mālama i ke kō.

ʻO Formin kahi hana antidiabetic, ka hopena o kahi o nā mea maʻi. ʻAʻole pono e hoʻokō i kāna hoʻokele kūʻokoʻa, ʻoiai he nui nā contraindications. Ma mua o ka hoʻohana ʻana, pono ʻoe e kamaʻilio i ka loea e hiki ai ke loiloi i nā āpau āpau a me ka hopena e pono ai ke olakino.