Nā ʻōlelo aʻoaʻo Glimekomb - (Glimekomb) i hoʻohana
Ka puka ʻana - nā papa: lemi-cylindrical, mai ke keʻokeʻo a keʻokeʻo me kahi ʻono a i ʻole ka melemele a i ʻole (hiki ke waiho ʻia nā lau), me kahi kīwī a me kahi bevel (10 mau polu. nā kāmela, ma kahi pūpū kāleka 5 mau paona, 30, 60 a me 120 pcs.
Nā mea e pili ana i ka 1 papa:
- kamaʻilio pū ʻia - 500 mg,
- gliclazide - 40 mg.
Nā kumuhana hou: criumarmellose sodium, povidone, magnesium stearate, sorbitol.
Nā hōʻailona no ka hoʻohana ʻana
- type 2 diabetes mellitus i ka hihia o ka hoʻopono o ka meaʻai meaʻai, ka hana kino a me ka monotherapy o mua i ka gliclazide a i hui aku paha.
- type 2 diabetes mellitus me ka pae o ka hoʻoliʻi koko a paʻa pono ʻole - e hoʻohuli i ka lāʻau i hoʻohui ʻia ma mua o ʻelua mau lāʻau (gliclazide a metformin).
Nā Hoʻohui
- huahuʻi,
- maʻi ketoacidosis maʻi, maʻi kanesa precoma a me ka coma,
- maʻi diabetes type 1
- pūpū hema
- nā maʻiʻeha a me nā maʻi paʻa i hele pū ʻia e ka kiko hypoxia: i ka wā hope myocardial infarction, ʻeha a me ka puʻuwai puʻuwai, pīhoihoi,
- nā hopenaʻeha e hiki ai ke alakaʻi i kahi loli i ka hana o ka hana: ka maʻi ʻeha, keehi, ka hoʻihoʻi,
- pilikia hanalei,
- lactic acidosis, me ka mōʻaukala o
- nā maʻi maʻi pāpaʻi, ke kau ākea nui, nā hōʻeha, nā hōʻeha papa nui a me nā kūlana ʻē aʻe e koi ana i ka lāʻau lapaʻau,
- porphyria
- lilo i ka maʻi kaulike
- ka adherence i ka meaʻai haʻahaʻa-emi (emi iho ma mua o 1000 kaleka / lā),
- ka wā hapai a me ka umauma.
- ke hoʻokō nei i kahi hoʻokele radioisotope a i ʻole X-ray me ka hoʻomaka ʻana o ka iodine-i loaʻa ka hopena me ka medium (48 mau hola ma mua a me 48 mau hola ma hope o).
- con conidance con miconazole,
- hypersensitivity o kekahi mea hoʻoikaika a i ʻole kōkua o ka lāʻau i ka lāʻau a i ʻole nā derivatives sulfonylurea.
ʻAʻole i ʻōlelo ʻia ʻo Glimecomb no nā maʻi i ʻoi aku ma mua o 60 mau makahiki o ka mea e hana i ka hana kino olakino (ma muli o ka pilikia nui o ka hoʻomohala ʻana i ka waikena lactic).
- kahi maʻi thyroid me ka pale ʻole ʻana o kāna hana,
- lawa adrenal,
- ʻiliʻala maʻi
- hypofunction o nā aniani pituitary gland.
ʻLoe a me ke kākele
Pono ʻia ka Glimecomb ma ke ʻano o ka manawa a ma hope o ka pāina ʻana.
E hoʻoholo i ke kauka i ka nui pākahi, ma muli o ke kiʻekiʻe o ka glucose i ke koko.
ʻO ka pākuʻi lā i kēlā me kēia lā, e like me ke kānāwai, he 1-3 nā papa, a laila ʻokoʻa ka hoʻonui ʻia ʻana, inā pono, a hiki i ka hopena paʻa o ka maʻi.
ʻO ka papa helu nui loa i kēlā me kēia lā he 5 papa.
Hoʻokaʻawale ʻia ka ʻokoʻa o ka lā i kēlā me kēia lā 2 - kakahiaka a me ke ahiahi.
Nā hopena hopena
- nā maʻi pā: ka makulopapular rash, itching, urticaria,
- mai ka ʻaoʻao o ka metabolism: me kahi kīnā ʻole kūpono a me ka uʻi ʻana o ka regimen dosing - hypoglycemia (ka pōloli, ka ʻeha, ka luhi, nā nāwaliwali nui, ka maʻi hoʻonanea, ka nui ʻana o ka luhiluhi, nā pilikia neʻe iki ʻana me ka pōkole, ka hoʻomohala ʻana i nā neʻe, ka palpitations, me ka holomua o ka hypoglycemia - ka lilo ʻana o ka pale a me ka hoʻomaopopo ʻana) , i kekahi mau hihia - ka lactic acidosis (ʻeha o ka ʻōpū, ke ea ʻana o ka hanu, hoʻohaʻahaʻa i ke koko, ke kuapo nei, myalgia, nāwaliwali, hypothermia, reflex bradyarrhythmia),
- mai nā ʻenehana hemopoietic: luhi - pale ʻana i ka hematopoiesis o ka iwi o ka iwi (thrombocytopenia, anemia, leukopenia),
- mai ka pānaʻi ʻana o ka hana kūwaho: mau i ka momona, nā huina dyspeptic (ʻōpū metallic i loko o ka waha, ʻehaʻeha, ʻeha, ka ʻeha ʻana i ka epigastrium), ʻaʻole loaʻa ka pōʻino o ka ate (hoʻonui i ka hana hepatic transaminases a me ka alkatine phosphatase, cholestatic jaundice, hepatitis).
- ʻO nā mea'ē aʻe: ʻike maka.
ʻO nā hua o nā sulfonylureas, ka mea e komo i kekahi o nā mea hana o ka Glimecomb (glyclazide), hiki ke hōʻeha i nā hopena like ʻole: vasculitis allergic, anemia hemolytic, agranulocytosis, pancytopenia, erythropenia, a me ka hoʻoweliweli ʻana o ka nūnū.
Ma ka hanana o kahi overdose a ma ka heleʻana i nā mea kūpono ma muli o ka metformin e māhele ʻia ana i ka lāʻau, hiki i ka hoʻomohala ʻana o ka acidosis lactic - kahi ʻano e koi ai i ka nānā maʻi olakino (i hōʻike ʻia kona mau hōʻailona ma luna). Pono e mālama ʻia ka lāʻau lapaʻau i loko o ka haukapila. ʻO ka hopena kūpono loa no kēia hoʻopiʻi ʻana ʻo ka hemodialysis.
Eia kekahi, hiki i kahi overdose ke alakaʻi i ka uluʻana o ka hypoglycemia, no ka mea, ʻo glycazide kahi hapa o ka lāʻau. Me ka ʻoluʻolu a me ka hoʻohuihui ʻana i ka maʻi o ka hypoglycemia, pono e lawelawe ʻia i nā glucose (a me ka dextrose) a i ʻole ka puna wai kō i lawe ʻia. Ma ka hopena o ka hypoglycemia koʻikoʻi (hōʻike i ka nalowale o ka ʻike) 40% glucose (dextrose) i hoʻopaʻa ʻia i intravenously, subcutaneously a intramuscularly glucagon. Ma hope o ka hoʻomanawanui hou o ka mea maʻi, pono ia e hāʻawi ʻia i nā meaʻai momona aʻai e pale ai i ka hoʻomohala ʻana o ka hypoglycemia.
Nā ʻōlelo kikoʻī
Ua kuhikuhi ʻia wale ʻia ʻo Glimecomb i nā maʻi e loaʻa i nā meaʻai maʻamau me ka haʻahaʻa haʻahaʻa haʻahaʻa, aia ia i ka ʻaina kakahiaka.
I ka wā mālama, pono ʻoe e kiaʻi pono i ka pae o ka glucose i ke koko ma luna o ka ʻōpū ʻole a ma hope o ka ʻai ʻana, ʻoi aku hoʻi i nā lā mua o ka lawe ʻana i ka lāʻau.
Pono e hoʻopau ʻia ʻo Glimecomb i mau hola he 48 ma mua o ka hoʻokō ʻana o kahi mana i loko o ka iodine e loaʻa ana i ka radiopaque a i ʻole ʻia Hiki iā ʻoe ke hoʻomau i ka lawe ʻana ma mua o nā hola 48.
Pono e noʻonoʻo i ka derivatives sulfonylurea (ma kēia hihia, glyclazide) hiki i ka hypoglycemia, i kekahi mau hihia i kahi hana koʻikoʻi a lōʻihi. ʻO ka pinepine pinepine nō ka ulu ʻana o kēia ʻano me ka mālama haʻahaʻa-ʻohi, ma hope o ka hoʻoikaika kino o ka manawa a lōʻihi paha, ma hope o ka inu ʻana i ka wai ʻaka, ʻoiai e lawe ana i kekahi mau mea maʻi hypoglycemic. I mea e pale aku ai i ka hoʻomohala ʻana o ka hypoglycemia, pono e mālama pono a koho ʻia ʻo ia i kahi wai no kēlā me kēia mea maʻi a hāʻawi iā ia i ka ʻike holoʻokoʻa e pili ana i ka hana e hiki mai ana.
Hoʻoponopono ʻia ke ʻano o Glimecomb i ka wā e hoʻololi nei i ka meaʻai, me ke koʻikoʻi a me ke kaumaha.
ʻO nā ʻōkuhi maʻi e pili ana i ka hana a ka lāʻau hypoglycemic:
- nā mea maʻi me ka lawa o ka pituitary-adrenal,
- kanaka kahiko
- nā mea i loaʻa ʻole i ka meaʻai kūpono,
- nā mea maʻi me kahi kūlana nāwaliwali ākea.
Ka hoʻonui aku i ka pōloli, nā waiʻona a me nā huahana anti-inflammatory a me ka hōʻemi o ka hypoglycemia.
Hiki i Guanethidine, reserpine, clonidine a me nā beta-blockers ke uhi i nā hōʻailona hōʻailona o ka hypoglycemia.
I nā maʻi lēpaʻi me ka syndrome febrile, ke ahi ākea, nā hōʻeha a me nā hōʻuluʻulu nui o ka hōʻoki ʻana, hiki ke hoʻopau ʻia ka Glimecomb I ka wā hana, pono ia e nānā i nā hana renal a me ka manawa maʻamau (ma kahi o 2 mau manawa i ka makahiki) e hoʻoholo i ka lactate i loko o plasma. I ka hihia o ka acidact lactic, pono ia e kāpae i ka lāʻau lapaʻau.
Ke hoʻolālā nei i ka hāpai ʻana a i ka hopena o kona hōʻino i ka wā o ka hoʻohana ʻana i ka lāʻau, pono ia e kāpae i ka lawe ʻana a kuhikuhi i ka lāʻau lapaʻau.
I ka wā mālama, pāpā ʻia ka waiʻona. Pono e mālama pono i ka wā e alakaʻi ana i ke kaʻa a hana i nā ʻano ʻoihana ʻē aʻe paha e koi ai i ka nānā nui, ʻo ka wikiwiki o ka noʻonoʻo ʻana o ka noʻonoʻo a me ke kaʻa.
Hoʻohui nūhou
Hoʻonui ʻia ka hopena hypoglycemic o Glimecomb e nā mea'ē aʻe e pili ana i ka hypoglycemic agents (e.g., insulin, acarbose, biguanides), tubular secretion blockers, long-acting sulfonamides, blockers N2-histamine reseptor (contoh, cimetidine), antenaagulants Coumarin, agen antifungal (fluconazole, miconazole), inhibitor -iotonin-kononon-azonzone-azonzone-azonzone-azonzone-azonzone-azonzone , nā mea kanu anti-TB (ethionamide), fibrates (clofibrate, bezafibrate), anabolic steroid, oxytetracycline, fenfluramine, disopyramide, tetracycline, guanethidine, fluoxetine, c cyclophosphamide, allopurinol, reserpine, chloramphenicol, pyridoxine, theophylline, pentoxifylline, bromocriptine.
Hypoglycemic hana Glimekomba hoʻonāwaliwali i carbonic anhydrase nā mea kūpale (acetazolamide), thiazide diuretics, likiuma, Anati-epileptic ai '(phenytoin), thyroid hormones blockers kali kalipuna auwai a, steroid, barbiturates, agonists (epinephrine, clonidine), rifampicin, baclofen, chlorthalidone, diazoxide, furosemide, glucagon, isoniazid, triamteren, terbutaline, morphine, asparaginase, salbutamol, danazol, ritodrin, i nā koina nui - nā contraceptives waha, estrogens, chlorpromazine, nikotine hoʻohuihui hanehana.
ʻO nā hua lāʻau e pale ana i ka hematopoiesis pumehana o ka iwi e hoʻonui i ka pono o myelosuppression, ethanol - ka hoʻomohala ʻana i ka waikena lactic.
I ka hihia o ka hui pū ʻana me ka glycosides cardiac, hoʻonui ʻia ʻo Glimecomb i ka nui o ka waihona o ka ventricular extrasystole.
Hoʻonui ka Nifedipine i ka hoʻopili a me ka hoʻolalelale i ka hoʻopau ʻana o ka metformin
Me ka hoʻohana ʻana i ka lōʻihi, hoʻāla ʻia nā ʻaila cationic i ka ʻōpala (procainamide, amiloride, vancomycin, quinine, quinidine, digoxin, triamteren, morphine, ranitidine) e hoʻonui i ka nui o ke kukuna o ka metformin i ke koko ma o 60%, furosemide - e 22%.
Hoʻokuʻu ka Metformin i ka nui o ka kukuna a me ka hapa hapa o ka furosemide e 31 a me 42.3%, kekahi.
E hoʻokuʻu i ke ʻano, ka pūpū a me ka hoʻopili ʻana Glimecomb ®
Nā papaʻaina mai ke keʻokeʻo a keʻokeʻo me kahi poli a iʻa paha i ka melema, ka cylindrical flat, me ka chamfer a me ka pilikia, ʻo ka marbling e ʻae ʻia.
1 kōpō | |
gliclazide | 40 mg |
metformin hydrochloride | 500 mg |
Nā mea kūʻai: sorbitol, povidone, sodium croscarmellose, magnesium stearate.
10 kamepiula - nā papaki blister (6) - nā ʻeke pepa.
Ka hana lāʻau lapaʻau
Hoʻohui ʻia nā lāʻau hypoglycemic no ka hoʻohana waha. ʻO Glimecomb® ka hui pūpū o ʻelua mau lawelawe hypoglycemic waha o ka hui biguanide a me ka hui sulfonylurea.
Loaʻa iā ia ka hana pancreatic a me ka extrapancreatic hana.
ʻO Glyclazide kahi derobe o ka sulfonylurea. Hoʻonui i ka mea huna o ka insulin e ka pancreas, hoʻonui i ka ʻike ʻana o nā ʻiʻo peripheral i insulin. Hoʻowalewale i ka hana o nā kinipili intracellular - kūlohelohe glycogen synthetase. Hoʻihoʻi hou ia i ka mua o ka mea huna o ka mea huna o ka insulin, e hoʻēmi ana i ka manawa manawa mai ka manawa ʻai e ʻai ai i ka hoʻomaka ʻana o ka huna ʻana i ka insulin, a hoʻēmi ana i ka hyperglycemia postprandial. Hāpai i ka hoʻopilikia ʻana i ka metabolism o ka kalapona, ke kau nei i ka microcirculation, hoʻēmi i ka pānaʻi platelet a me ka hōʻuluʻulu ʻana, hoʻohemo i ka hoʻomohala ʻana o ka trombosis parietal, hoʻāliʻi i ka hanana o ka vascular a me ka pale ʻana i ka hoʻomohala ʻana o ka microthrombosis a me atherosclerosis, e hoʻihoʻi i ke kaʻina o ka physiet parietal fibrinolysis. Ke hoʻolōʻihi i ka hoʻomohala ʻana o ka retinopathy diabetes i ka papa non-proliferative, me ka maʻi nephropathy diabetes me ka hoʻohana lōʻihi, ʻike ʻia kahi emi nui i ka proteinuria. ʻAʻole ia e alakaʻi i ka hoʻonui nui o ke kaumaha kino, no ka mea aia kahi hopena nui ma ka wana o ka neʻe o ka huna ʻana o ka insulin a ʻaʻole ia i hoʻoulu i ka hyperinsulinemia, ke kōkua i ka hoʻemi ʻana o ke kaumaha o ke kino i ka mea hoʻomoea o ka lālani, ma muli o kahi kīnā kūpono
Aia ʻo Metformin i ka hui o nā biguanides. Hoʻemi ia i ka hoʻoliʻiliʻi o ka glucose i ke koko ma ka hoʻokaʻawale ʻana i ka gluconeogenesis i loko o ka ate, e hoʻemi ana i ka komo ʻana o ka glucose mai ka digestive tract a hoʻonui i ka hoʻohana ʻana i nā ʻōnaehana. Hoʻemi i ka paneʻana o ka triglycerides, cholesterol a me LDL (i hoʻoholo ʻia i kahi ʻōpū ʻole) i ka serum o ke koko a ʻaʻole hoʻololi i ka paʻa o nā lipoproteins o kahi kūʻokoʻa ʻē aʻe. Kōkua i ka hoʻokūʻē ʻana a hōʻemi paha i ke kaumaha o ke kino. I ka nele ʻana o ka insulin i loko o ke koko, ʻaʻole i hōʻike ʻia ka hopena therapeutic. ʻAʻole hoʻonā ka hopena hypoglycemic. Hoʻonui i ka waiwai fibrinolytic o ke koko ma muli o ke kaohi ʻana o ka inhibitor o ka profibrinolysin activator (plasminogen) kikoʻī.
Nā hui like ʻana o nā hui nosological
Ke poʻo nui ICD-10 | ʻO ka hui like ʻana o nā maʻi e like me ka ICD-10 |
---|---|
E11 Mellitus non-insulin-diabetes | ʻO ka maʻi diabetes Ketonuric |
Ike hoʻoneʻe o ka ʻaila kino | |
Non-insulin hilinaʻi mellitus maʻi mellitus | |
ʻAno maʻi type 2 | |
ʻAno maʻi type 2 | |
Non-insulin dependant diabetes | |
Mellitus non-insulin-hilinaʻi mellitus | |
Mellitus non-insulin-hilinaʻi mellitus | |
Ke kūlohelohe ʻia | |
Hoʻokomo i ka maʻi diabetes | |
Coma lactic acid diabetes | |
Kaola ʻai ma ka huina | |
ʻAno maʻi type 2 | |
ʻAno maʻi II | |
ʻO ka maʻi diabetes mellitus i ka wā pākeke | |
ʻO ka maʻi diabetes mellitus i ka wā kahiko | |
Non-insulin hilinaʻi mellitus maʻi mellitus | |
ʻAno maʻi type 2 | |
ʻAno II mellitus mika |
Lapaʻau lāʻau
Hoʻomoe a me ka hoʻolele
Ma hope o ka lawelawe waha, ua kiʻekiʻe ke komo ʻana. I ka wā e lawe ai i ka pākaukau o 40 mg C max i loko o ke kaila koko a hōʻea ma hope o 2-3 mau hola a lilo i 2-3 μg / ml. ʻO ka pilina protein Plasma he 85-97%.
Metabolism a me ka hoʻopā ʻana
Hoʻopili i ka puʻuwai. T 1/2 - mau hola 8-20. ʻO ia ka mea i hoʻopuka nui ʻia ma nā ʻano o nā metabolites e nā keiki - 70%, ma o nā ʻōpū - 12%.
I ka poʻe maʻi nā maʻi, ʻaʻole i ʻike ʻia nā loli nui i loko o nā laikini pharmacokinetic.
Hoʻomoe a me ka hoʻolele
Ma hope o ka lawelawe waha, ʻo 48-52% ka lilo ʻana. Hoʻopili koke ʻia mai ka lolo. ʻO ka bioavailability piha (ma kahi ʻōpū ʻole) he 50-60%. Loaʻa ka C max i ka plasma koko ma hope o 1.81-2.69 h a ʻaʻole iʻoi aku i ka 1 g / ml. ʻO ka haʻahaʻa me ka meaʻai e hōʻemi ana i ka C max i ka plasma i ka 40% a me ka hoʻolō ʻana i kona loaʻa ʻana ma ka 35 min. Hoʻololi ke kūmaha protein Plasma. Hiki i ka metformin ke hōʻuluʻulu i nā pona koko ʻula.
ʻO T 1/2 mau hola 6.2, ua hoʻihoʻi ʻia e nā keiki, ka hapanui o ka loli.
Nā kumukūʻai i nā lāʻau lapaʻau ma Moscow
Kau inoa inoa | Kauoha | Manaʻo no | Kumukuai no 1 papa. | Tauhi no kēlā me kēia pā, hoʻoulu. | Nā lāʻauʻai |
---|---|---|---|---|---|
Glimecomb ® papa 40 mg + 500 mg 40 mg + 500, 60 mau ʻōneka. |
papa 40 mg + 500 mg 40 mg + 500, 30 pcs.
Waiho i kāu manaʻo
Nā ʻIke Kūlana Kūlana, ‰
ʻO nā palapala inoa inoa Glimecomb ®
LSR-009886/09
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ʻOi aku nā mea hoihoi aʻe
Iwai a aie ke dttla.
ʻAʻole ʻae ʻia ka hoʻohana ʻana i nā ʻoihana.
ʻO ka ʻike e hana no nā lāʻau lapaʻau.
Ke noi
Hoʻolako ʻia ʻo Glimecomb no ka hoʻohana ʻana i nā mea maʻi me ka loaʻa ʻana o ka maʻi maʻi maʻi 2. He mea nui ia e kāl ana kēia lāʻau lapaʻau i ia ʻano ʻano o ka maʻi i ka manawa e hoʻōla ai ka hana kino a me kahi palapala ʻai hoʻokaʻa kūikawā i lawe mai i ka hopena kūpono. ʻO kēia ka mea i kuhikuhi i kēia lāʻau lapaʻau i ka hoʻopiʻi ʻana me ka hoʻokūkū paʻa ʻole, e hui pū ai i nā lāʻau ʻelua (ʻoi aku ka metformin maʻamau a me ka gliclazide) e hui pū ai me ka hana pilikino a me ka meaʻai.
I ka wā o ka mālamaʻana me Glimecomb, kiaʻi mau ka mālama ʻana i ke kōpaʻa koko o ka mea maʻi ma mua a ma hope o ka ʻai ʻia e pono ai (pono e uku ʻia i ka pule mua o ka komo ʻana).
E hoʻokuʻu i nā palapala
Loaʻa i ka Glimecomb kahi puka hoʻokuʻu hoʻokahi i ke ʻano o nā papa. Ua mahele ʻia ka lāʻau lapaʻau e ke ʻano o ka hoʻopiha ʻana i nā pūʻulu penei:
- i loko o nā hue plastik i ka pauka pepa. Aia i loko o kēia kīʻaha he 30, 60 a 120 mau papa,
- i loko o kahi pahu pahu me nā pololi o nā papa he 10 i hoʻokahi. Hoʻokahi ka pūpū 6 makana,
- i loko o kahi pahu kāleka me nā palaha o nā papa he 20 i loko o hoʻokahi. ʻO ka pānaʻi hoʻokahi ʻano 5 kōpī.
ʻO nā papa i loko o ke ʻano o kahi silopani papa, ʻoi loa ka keʻokeʻo (beige, kinikini a me nā melemele ke ʻae ʻia). He pōpilikia a nā pōpō a me kahi bevel. ʻO ka hoʻonohonohoʻana o Glimecomb e pili ana i ka metformin a me hydrochloride ma ka nui o 500 mg, me ka glycoslide 40 mg. Eia kekahi, ʻo povidone, magnesium stearate, sorbitol a me ka sodium croscarmellose aia i loko o kahi liʻiliʻi.
Nā hōʻailona o ka lāʻau Glimecomb ®
- type 2 diabetes mellitus (non-insulin dependant) me ka hiki ʻole o ka mālama ʻana i ka lāʻau ʻaina, hoʻomaʻamaʻa a me ka mālama ʻana i ka mua me ka metformin a i ʻole gliclazide,
- ka hoʻololi 'ana o ka hoʻolaha mua ma mua o nā lāʻau lapaʻau (metformin a me gliclazide) i nā mea maʻi me ka diabetes mellitus type 2 (non-insulin-dependance) me kahi paʻukūʻa mau me ka hala o ka nui o ka glucose.
Aia ka helu ICD-10 | Hōʻike ʻano |
E11 | ʻAno maʻi type 2 |
Nā ʻōkuhi no ka hoʻohana
Lawe ʻia a Glimecomb ma ke ʻano, ma hope o ka ʻai ʻana a me ia pū paha, e pili ana i ka ʻimi. I ka wā e mālama ai me nā papa, pono ʻoe e pili i kaʻai haʻahaʻa-low i ʻōlelo ʻia e nā poʻe loea, pono e hoʻopili i ka ʻaina kakahiaka. Pono ka manaʻo o nā papa maʻa ʻaʻole wale ke kiʻekiʻe o ka maʻi mellitus o ka lua o ka maʻi, akā, ʻo ke ʻano a me ke ʻano kino o ka mea maʻi. Eia kekahi, ʻo nā loli i ka papa e koi ai ke koikoi me ke kauka (loaʻa ka wikiwiki a me ka inu ʻawaʻawa). Pono e mālama i ka lāʻau lapaʻau i kahi maloʻo maloʻo ma kahi wela o ke kūʻaʻa ʻole ma mua o 25 tikelika Celsius. Pāla ola i 2 mau makahiki.
Pono e hoʻomanaʻo ʻia o nā huahana sulfonylurea i loko o ka lāʻau lapaʻau e hiki ke kumu i ka hypoglycemia. I mea e hōʻalo ai i kēia, pono e koho pono i ka pāʻai a me ka meaʻai no kēlā me kēia hihia pākahi. I ka wā o ka mālama ʻana, pono e mālama ʻia a mālama pono i ke kaʻa ʻana i ke kaʻa a me ka hana e koi ana i kahi kiʻekiʻe o ka neʻe ʻana a hoʻonui nui.
Ka hoʻoponopono ʻia ʻana
Lawe ʻia ka lāʻau ma mua a ma hope koke iho o ka ʻai ʻana. Hoʻoholo ʻia ka nui o ka lāʻau e ke kauka ponoʻī no kēlā me kēia maʻi, e pili ana i ke kiʻekiʻe o ka glucose koko.
ʻO 1-3 ka papa ma mua he 1-3 papa / lā me kahi koho o ka maʻi a hiki i ka loaʻa ʻana o kahi uku mau o ka maʻi. ʻO ka palena nui loa i kēlā me kēia lā he 5 papa.
Hoʻohana pinepine ʻia ka lāʻau lapaʻau i nā manawa 2 / lā (kakahiaka a i ke ahiahi).
Nā hopena hopena
Hiki i nā hopena leʻaleʻa i hiki ke ʻike ʻia i ka wā e lawe ai iā Glimecomb i ka mea pinepine ma muli o kona overdose a i ʻole kūpono ʻole me ke kino maʻi kūloko o ka mea maʻi. A ʻo nā mea e pili ana i ka derony o ka sulfonylurea e hoʻonui i ka hōʻemi i ka nui o nā hopena o ka ʻaoʻao. Hoʻohana ʻo ia ka hana kūpono no ka mea maʻi me ka hoʻomohala ʻana i ka acidosis lactic, hele pū me ka migraines, nāwaliwali mau, ka nui o ka hiamoe, a me ka hōʻoki ʻana i nā ʻeha ma ka ʻōpū o ka ʻōpū a me ka hoʻoluhi ʻana i ke kaomi ma loko o nā ʻalā.
Hiki i nā hopena i ka makemake i ka wā e lawe ai iā Glimecomb:
- ka hoʻomohala ʻana o ka hypoglycemia a me ka lactocidosis me nā hōʻailona eha e pili ana,
- ke ʻano o ke kinipōpō a me ka lemulewa,
- ka leʻaleʻa mau ʻana i ka ʻōpū o ka ʻōpū,
- hoʻemi i ka makemake maʻamau,
- ka manawa maʻamau o ka loaʻa ʻana o ke koko i loko o ka waha a me ka ʻāʻī
- ke ʻano o ka hoʻomohala ʻana i nā maʻi o nā puʻuwai koʻikoʻi (hepatitis, etc.)
- maʻi kūlohelohe i nā mea like o ka pūnaehana (urticaria, itching, tumors,
- ʻulaʻula, nā ʻano rashes),
- aia nā hihia o ka hōʻemi kino a ke lawe ʻana iā Glimecomb.
Inā loaʻa iā ʻoe nā hōʻailona ma luna, pono e kūkā koke i kahi loea.
I ke alakaʻi ʻana i nā lāʻau lapaʻau Lūkia, e hoʻohālike ke kumukūʻai o Glimecomb mai 200 a 600 mau rubles, e hilinaʻi nei i ka pauka a me ka helu o nā papa i loko, a me ka mea i hoʻolako a me nā wahi kūʻai. Ma ke kumukūʻai o ka lāʻau lapaʻau i hiki iā ia ke kūpono no kahi laulā o ka lehulehu, no laila e koi ʻia ma ka mākeke pharmacological. No laila ke kumukūʻai kumukūʻai ma nā hale kūʻai pūnaewele no nā papa Glimecomb he 40 mg + 500 mg 450 mau rubles no ka pāleka, aia kahi 60 papa. I nā lāʻau lapaʻau pūnaewele, ʻo ke kumukūʻai o ka lāʻau no nā papa 60 no like 500-550 rubles.
ʻO nā mea hoʻohālike Glimecomb kēiaʻano:
- ʻO Gliformin (ma kahi o 250 mau rubles no 60 mau papa), ka lula o ka hana a ua like ia me ka Glimecomb, ua like ka mea like, akā naʻe ke ʻano o ka insulin i kēia lāʻau lapaʻau e hoʻonani iki.
- Diabefarm (no nā papa 60, pono ʻoe e uku e pili ana i ka 150 mau rubles). Aia ia ka mea e paʻa ai ka glyclazide - 80 mg, ke kuhikuhi nei i ka hoʻopau ʻana i nā pilikia like me Glimecomb.
- ʻO Gliclazide MV (ke kumukūʻai kumukūʻai no nā papa 60 he mau rubles). He ʻano kūlike ia mai Glimecomb, aia wale nō ka 30 mg o glycoslazide. ʻO nā hōʻailona no ka hoʻohana ponoʻana e like me ka lāʻau lapaʻau mua.
Ke keu
I kahi hihia o ka overdose o Glimecomb, loaʻa i ka lactacidosis a me hypoglycemia. Ke pale aku i kēia mau kūlana, ʻo ka hemodialysis pinepine ke kuhikuhi. Pono ke Glycemia i ka hoʻohana ʻana i ka glucose a i ʻole ka hopena o ke kō i loko (me ke ʻano maʻalahi a maʻalahi paha). I nā hihia koʻikoʻi nui, a hiki i ka nalowale o ka ʻike, pono kahi lawelawe o ka glucose% 50% (hiki ke hoʻololi pū ʻia me glucagon). Ma ke hoʻomaka ʻana o ka mea maʻi i ka ʻike, pono ia e hāʻawi iā ia i ka meaʻai kiʻekiʻe-kalapula e pale ai i ka holomua o ka hypoglycemia.
Eia kekahi, inā loaʻa ka wai hoʻōla me ka ʻole o ka hoʻopiʻi nui ʻana, hiki paha i ka mea maʻi ke hōʻoluʻolu ma ke ʻano o ka haunaele a hiki i kahi nāwaliwali, maʻi pākaha, hōʻulu a me ka maʻi o ka maʻi, a me nā neʻe migraines. I kēia hihia, pono ʻoe e hoʻopili i ke kōkua mua. I ka home, pono ia e holoi i ka ʻōpū a hoʻokaʻa koke i ka lāʻau lapaʻau mai ka hāhai ʻana o ke aila Inā pono, hiki i kahi hoʻokipa ma hope ma lalo o ka mālama mau ʻana o kahi loea.
ʻO ka hoʻohana ponoʻana o kēia lāʻau lapaʻau ma luna o ka kaohi o ke kō koko koko i ka maʻa o ke ʻano lua, a me kāna uku uku, hoʻonā nui ʻia ka lāʻau lapaʻau a loaʻa i nā loiloi maikaʻi loa. Akā poina poina e pili ana i nā hopena ʻaoʻao i hāʻawi ʻia e kēia lāʻau lapaʻau. Ma muli o ka papa nui o nā hopena kūpono ʻole e ʻike ʻia nā loiloi maikaʻi ʻole o nā maʻi. Ma lalo aʻe nei kekahi o nā loiloo e pili ana i kēia mau peni:
ʻO Glimecomb, e like me ka hōʻike ʻana ma kahi hōʻike, he lāʻau lapaʻau kaulana kaulana loa i ka mālama ʻana o ka maʻi maʻi type 2. ʻO ka hui pū ʻana o ke kumukūʻai, maikaʻi a me ka hana kiʻekiʻe e hoʻowalewale ʻia nā papa i nā mākena pharmacological.
Loaʻa ka hopena
Mai ka pūnaehana endocrine: hypoglycemia (i ka hana hewa ʻana o ka dimen regdate a me ka ʻai ʻole) - hōʻeha ka ʻeha, ke kaumaha, ka pōloli, ka nui ʻana o ka luhi, nā nāwaliwali nui, palpitations, dizziness, ka hoʻonohonoho ʻana o nā neʻe, ka pilikia o ka wā neʻe, a me ka holomua o ka hypoglycemia, ka hala ʻana o ka pale ʻana, nalowale o ka ike ana.
Mai ka ʻaoʻao o ka metabolism: i kekahi mau hihia - ka lactic acidosis (nāwaliwali, myalgia, ʻeha hanu, nā kahe, ʻeha o ka ʻōpū, hipotermia, hoʻoemi i ke koko, bradyarrhythmia).
Mai ka pūnaehana ʻana: dyspepsia (ʻeha, ʻeha, ka ʻeha kaumaha i loko o ka epigastrium, kahi ʻatikala "metallic" i loko o ka waha), i ka hōʻemi ʻana i ka makemake (me ka palu o kēia mau ʻano i ka ʻai me ka ʻai ʻana), ka maʻi hepatitis, jaundice cholestatic (lawe ʻia ka lāʻau) , nā hana i hoʻonui ʻia o ka transaminases hepatic, phosphatase alkaline.
Mai ka ʻōnaehana hemopoietic: līkuhi - kaohi ʻana o ka hematopoiesis sumsum lua o ka iwi (anemia, thrombocytopenia, leukopenia).
He maʻi kūlohelohe: itching, urticaria, maculopapular rash.
ʻO nā mea'ē aʻe: ʻike maka.
I ka hihia o nā hopena kaulike, e hoʻemi ʻia ka nui o ka lāʻau a i ʻole ke hōʻola ʻokoʻa.
ʻO nā hopena maʻamau o nā derivatives o ka sulfonylurea: erythropenia, agranulocytosis, anemia hemolytic, pancytopenia, vasculitis alerine, hoʻoweliweli ma ka hopena o ke ola.