Ke lāʻau lapaʻau Mefarmil: nā ʻōlelo no ka hoʻohana ʻana

Aia ka lāʻau i ka pūʻulu o nā biguanides, ʻo ka mea ikaika e dimethyl biguanide. Loaʻa ia mai ka mea kanu Galega officinalis. Hoʻopili ka Metformin me ke kāpili ʻana o ka glucose i ka peka (kaʻenehana gluconeogenesis), a laila e hoʻohaʻahaʻa i ke pae o ke kō koko. Noho like me kēia, hoʻonui ka lāʻau i ka mālama ʻana i nā mea kū i ka insulin, e hoʻomaikaʻi ana i kona komo ʻana, hoʻomaikaʻi i ka oxidation ʻoi aʻe o nā momona momona, hoʻonui i ka hoʻohana pono peripheral i ka glucose, a hoʻoneʻe i kona komo ʻana mai ka hana o ka digestive tract.

Mālama ka mea hana i ka hoʻemi ʻana i ka hormone hoʻoulu i ka thyroid i ka serum o ke koko, hoʻohaʻahaʻa i ka cholesterol a me nā lipoproteins density haʻahaʻa, e pale ai i nā loli pathological i nā kīʻaha koko. Hoʻolimalima i ka coagulability koko, hoʻomaikaʻi i kāna mau waiwai rheological, a laila ke kōkua i ka hōʻemi i ka hopena o ka thrombosis.

Hoʻomaopopo nā poʻe Endocrinologists o Metformin i ka ʻike e hāʻawi ana i ka pohō i ke kaumaha i ka momona.

Nā kikowaena o Metformin

Nā metformin analogues e pili ana i kēia mau huahana: Glucofage, Metformin-BMS, Metformin hydrochloride, Metformin-vero, Metformin-Richter, Formmetin, Formin Pliv, Gliformin, Glucofag, Vero-Metformin Novoformin, Metospanin. Metfogamma, Siofor, Glycomet, Dianormet, Orabetika, Bagomet, Gliminfor, Glycon.

Mai ka nānā ʻana o ka hana pharmacological, ʻo kā Metformin's analogue he insulin.

Nā hōʻailona no ka hoʻohana ʻana

Hoʻohana ʻia ka hoʻohana ʻana o ka Metformin ma ka mālama ʻana i ke ʻano o ke ʻano maʻi type 2 me ka hana pena ʻole i mālama ʻia, me kahi ʻāina prediabetic. ʻO kahi palapala kuhikuhi pono no ka hoʻohana ʻana i ka maʻi diabetes type 2, i hele pū ʻia me ka obesity.

Hoʻohana ʻia ia ma ke ʻano he lāʻau paʻakikī i ka mālama ʻana i ka pohō o ka ʻōpū-visceral.

I ka wā i hoʻohana ʻia ai ma ka hana lapaʻau, ʻike ʻia nā loiloi o Metformin ma hope o ka hoʻokolohua ʻana i nā hoʻokolohua lapaʻau i hōʻoia iā lākou, i ka makahiki 2007 ua hāʻawi ʻia ka lāʻau lapaʻau no ka hoʻohana ʻana i ka hana pediatric no ka mālama ʻana i ka maʻi type 1, e like me kahi hoʻopiʻi i ka therapy insulin.

Nā ʻōkuhi no ka hoʻohana ʻana i ka Metformin

Lawe ʻia nā papa Metformin ma hope o ka ʻai ʻana, inu i ka wai o ka nui. ʻO ka pā mua a me ka mua ka 1000 mg i kēlā me kēia lā, ma luna o kahi mau hebedoma 1-2 e hoʻonui pinepine ʻia ka nui, hoʻoponopono ʻia kona waiwai ma lalo o ka kaohi o ka ʻikepili ʻana i ka pae o ka glucose i ke koko. ʻO ka lāhā loa ʻae ʻia he 3000 mg i kēlā me kēia lā. Hiki ke hoʻohana ʻia ka lāʻau i kēlā me kēia lā i ka manawa like, akā ma ka hoʻomaka ʻana o ka hoʻōla, i ka manawa o ka hoʻohālikelike ʻana, e noi ʻia e hoʻokaʻawale i nā ʻōmole 2-3, e kōkua ana i ka hōʻemi o ka hopena o ka lāʻau i ka gastrointestinal tract.

ʻIke ʻia ka ʻai kiʻekiʻe loa o ka lāʻau i loko o ke kaila koko he mau hola 2.5 ma hope o ka hoʻokele ʻana, ma hope o nā hola 6 he hoʻomaka ia e emi. Ma hope o 1-2 mau lā o ka hana maʻamau, e hoʻomau ʻia ka paʻa mau ʻana o ka lāʻau i loko o ke koko, e like me nā loiloi, hoʻomaka ʻia ʻo Metformin e ʻike ʻia i nā hopena he ʻelua mau pule ma hope o ka hoʻomaka ʻana o ka hoʻokō.

Me ka hoʻohui hoʻohui ʻana o ka Metformin a me ka insulin, pono ke nānā ʻana i nā kauka, me nā dosis kiʻekiʻe o ka insulin i ka haukapila.

Nā hopena hopena

Ke hoʻohana ʻia e like me nā ʻōlelo kuhikuhi, ʻike pinepine ʻia ka Metformin e ka mea maʻi, hiki ʻole i nā hopena ʻaoʻao. Inā loaʻa kekahi, a laila, e pili ana lākou me ka hoʻomehana ʻole ʻana o ka lāʻau i ka lāʻau, a i ʻole e launa pū me nā lāʻau lapaʻau ʻē aʻe, a i ʻole ka nui o ke ʻano.

Wahi a nā loiloi, ʻo Metformin ka mea pinepine e hoʻopiʻi i nā pilikia o ka digestive, hōʻike ʻia ma ka ʻano o ka dyspepsia i kekahi ʻano a i ʻole kekahi, ʻo kekahi o nā hōʻike o ka lactic acidosis. Maʻamau, ʻike ʻia kēlā mau hōʻailona i ka hoʻomaka o ka papa o ka mālama ʻana me ka lāʻau lapaʻau, a hala ma hope o ka manawa hoʻohālikelike. Wahi a nā ʻōlelo kuhikuhi, pono e hoʻohana ʻo Metformin i kēia hihia ma kahi hoʻemi haʻahaʻa, me ka acidosis lactic koʻikoʻi, kāpae ʻia ka lāʻau lapaʻau.

Me ka hoʻohana mau loa, hāʻawi aku ʻo Metformin i ka hōʻino ʻana o ka hoʻololi o ka vitamin B12 (cyancobalamin), e pale ai i kona komo ʻana i loko o ka ʻōpū, hiki i nā mea hōʻailona o ka anemia he hemahema B12. Pono kēia ʻano i ka hoʻoponopono ʻana i nā lāʻau lapaʻau.

Nā Mana Kūʻaiʻi Metformin

Hōʻike ʻia nā contraindications i loko o nā ʻōlelo aʻoaʻo Metformin:

• ʻO ka acidosis lactic o kēia manawa a i ʻole paha
• Ke kūlana precomatous
• Hypersensitivity o kekahi o nā lāʻau o ka lāʻau,
• ʻO ka renal function like ʻole, a me nā mea i hoʻopili ʻia e hiki ai ke hoʻonāukiuki i kēlā me kēia.
• Adrenal insufficiency,
• ʻO ka hana hema ʻole
• ʻO ka wāwae Diabetic
• ʻO nā kūlana a pau e kumu ai i ka dehydration (ka luaʻi, ke nānā ʻana) a me ka hypoxia (huʻokeʻo, cardiopulmonary failed),
• Alikaihue Pono e noʻonoʻo i ka hoʻohana pū ʻana o ka Metformin a me ka waiʻona e hiki ai ke hōʻeha i ka metabolic koʻikoʻi,
• ʻO nā maʻi maʻi maʻi i ka wā o ke kumu, i hele pū ʻia me ke kuni,
• Nā maʻi maʻi maʻi i ka lae o ka decompensation,
• Hoʻopuka ākea a me ka hoʻōla hou o ka postoperative,
• Haumakua

ʻO ka ʻae ʻana, e like me ka wā kamaliʻi, ʻaʻole i ʻike hou ʻia he contraindication ʻoki loa i ka lawe ʻana i ka lāʻau lapaʻau, ʻoiai hiki nō ke kuhikuhi i ka Metformin no ka mālama ʻana i ka maʻi maʻi gestational a me ka pōʻai o ke kī, akā, ma kēia mau hihia, e kū pololei ke ʻano o ka ʻoihana ma lalo o ka mālama mālama olakino.

Nā ʻōlelo kikoʻī

Me ka mana o ka metformin Metformin, ʻaʻohe pilikia o ka hoʻomohala ʻana i ka hypoglycemia, ʻaʻole i haʻalele ʻia kēlā ʻano pilikia i ka ululāʻau i ka maʻi maʻi o ka maʻi maʻi, e pono e hōʻike ʻia i ka mea maʻi. Hoʻohui ʻia ka hoʻohana ʻana o kēia lāʻau a me nā mea radiopaque intravascular e loaʻa ana i ka iodine. Hoʻohana pū kekahi ʻo Metformin a me kekahi lāʻau lapaʻau hou i ka nānā o ke kauka. I ka wā hana, hoʻopau ʻia ka lāʻau lapaʻau no 2-3 mau lā o ka wā hana. ʻO ke aʻo ʻana a Metformin e kuhikuhi i ka papaʻai i loko o ka manawa mālama, ka mea e pale ai i nā peaks koi a hāʻule i ka glucose koko, e hoʻonāukiuki i ka maikaʻi.