ʻO ka lāʻau ASK-Cardio: nā ʻōlelo i hoʻohana no ka hoʻohana

Ka lāʻau ASKL - He mea lāʻau lapaʻau antiplatelet e pale i ka hōʻiliʻili o ka platelet, a loaʻa iā ia kekahi hopena antipyretic, analgesic a me anti-inflammatory. Hoʻomaʻamaʻa ka aggregation ma hope o ka hoʻohana ʻana i ka lāʻau lapaʻau ma nā haʻahaʻa haʻahaʻa, e hoʻomau ka hopena no nā lā he nui ma hope o ka lawe ʻana i hoʻokahi waihona. ʻO nā papa coated coated kahi ʻano lāʻau lapaʻau ʻaʻole e hoʻokaʻawale i ka ʻōpū, a penei ke hōʻemi pololei ʻana o ka acetylsalicylic acid me ka gastosa mucosa a hoʻemi ʻia ka pohō. ʻO ka hakahaka ʻana o ka papa a me ka hoʻokuʻu ʻana i ka mea hoʻoikaika i ke kau wale ma ke ʻano o ka duodenum.

Nā hōʻailona no ka hoʻohana ʻana:
Ka lāʻau ASKL e hōʻemi i ka pilikia:
- make i loko o nā mea maʻi me ka maʻi ʻaopiko myocardial acute,
- make i nā poʻe maʻi ma hope o ka infococose myocardial,
- nā hōʻeha ischemic attack (TIA) a me kahi hahau i ka poʻe maʻi me TIA,
- ka morbidity a me ka make me ka pūlohi kūloko paʻa a paʻa ʻole.
Ka lāʻau ASKL no ka pale ʻana:
- ka thrombosis a me ka embolism ma hope o ka maʻi vascular (percutaneous transluminal catheter angioplasty (PTCA), carotid endarterectomy, coronary artery bypass grafting (CABG), arteriovenous shunting),
- thrombosis vein hohonu a me ka embolism pulmonary ma hope o ka lōʻihi o ka immobilization (hana ma hope-bedical operation),
- ka wahihā iokardial i loko o nā poʻe maʻi me ka hopena kiʻekiʻe o ka hoʻomohala ʻana i ka hoʻopiʻi cardiovascular (maʻi diabetes mellitus, ka hoʻokaumaha ʻia o ka maʻi arterial) a me nā poʻe me ka hopena maha o nā maʻi cardiovascular (hyperlipidemia, obesity, ulaula, ʻelemakule, etc.).
Ka lāʻau ASKL no ka pale ku ana i ka pona.

Ke ʻano o ke hoʻohana ʻana:
Hoʻomaʻamaʻa nā ʻōpio ma nā papa 1-2 o 75 mg a i ʻole 1 papa o 150 mg i ka lā i ka wā a ma hope o ka pāʻina.

Nā Palaki ASKL pau ia make ʻia me ka wai liʻiliʻi.
Me ka infarction myocardial hou a i ʻole no nā mea maʻi me ka hoʻowalewale myocardial infarction: ʻo ka wai saturating mua he 225-300 mg o ka acetylsalicylic acid 1 ka manawa i ka lā e hiki ai ke hoʻokō wikiwiki i ka wā o ka hui platelet. Hiki ke hoʻohanaʻia ka dosage o 300 mg i kēlā me kēia lā no kahi pōkole e like me nā hōʻike therapeutic.
Nā papa ʻaina e hiki ai i ke komo wikiwiki ʻana.

Nā hopena ʻaoʻao:
Mai ka ʻeha gastrointestinal, dyspepsia, ʻeha o ka ʻōpū epigastric a me ka ʻehaʻeha o ka ʻōpū, aia i kekahi mau hihia - ka hōʻeha ʻana o ka ʻeha gastrointestinal, nā hōʻailona hōʻike o nā hanana erosive a me ka ulcerative o ke ake o ka gastrointestinal, kahi ma nā hihia koʻikoʻi e hiki ai i ka ʻeha gastrointestinal i hōʻeha a me nā perforations ʻōnaehana kikowaena.
Ma muli o ka hopena antiplatelet ma nā platelets, hiki i ka acetylsalicylic acid ke hoʻonui i ka pilikia o ka kahe. ʻO nā ʻeha e like me ka hemorrhages intraoperative, hematomas, kahe koko mai ka genitourinary system, nosebleeds, kahe koko mai nā kūleʻa, ʻāʻī a i ʻole iki ʻole paha ke ʻano o nā ʻaihue e like me nā ʻōpū gastrointestinal, hemorrhages cerebral (e pili ana i nā mea maʻi me ka hypertension kuʻi ʻole a me / a i ʻole ka hoʻohana 'ana i nā mea lawelawe anti-hemostatic), ma nā hihia liʻiliʻi, hiki i ke ola ke hoʻoweliweli. Ma muli o ka hemorrhages ke alakaʻi i ka anemia postporrorragag a me ka / ana o ka anemia kakalula (ma muli o ka mea i kapa ʻia ʻo ka microbleeding latoc) me nā hōʻailona o nā kikowaena e pili ana a me nā hōʻailona kulekele, e like me ka asinia, ka palu o ka ʻili, hypoperfusion.
I nā mea maʻi me ka hypersensitivity pilikino i ka salicylates, hoʻomohala paha ka hopena o ka ʻili a me ka maʻi, e like me nā hōʻailona e like me ka hāmama, urticaria, edema, a me ka ʻeha. I nā maʻi me ka hoʻohuihui bronchial, loaʻa i ka nui o ka hōʻeha o ka bronchospasm hiki ke loaʻa, nā hopena alia mai ka maʻi maʻalahi a me ka hopena e pā ana i ka ʻili, ka pūnaehana hāpau, gastrointestinal tract a me ka ʻōnaehana cardiovascular.

ʻO nā hopena ʻino, me ka pīhoihoi anaphylactic, i ʻike pinepine ʻole ʻia. Kēia lohi, hiki ʻole i ka hana palaleka ke neʻe me ka hoʻonui ʻana i nā transaminases ate.
Ua nānā ʻia ka momona a me ka tinnitus.

Nā pālua:
Nā maʻi hoʻohālikelike i ka hoʻohana ʻana i ka lāʻau ASKL i:
- Hypersensitivity i ka acetylsalicylic acid, nā salicylates a i ʻole nā meaʻokoʻa o ka lāʻau lapaʻau.
- Hoʻokani lāʻau ākea e ka mōʻaukala o nā salicylates a i ʻole NSAID.
- Nā ʻōpū maʻi peptic akene.
- Diathesis Hemorrhagic.
- kōpū hāʻule kūwaho.
- Hoʻomaopopo ka paʻakai hemahema.
- hōʻeha maikaʻi ka naʻau.
- Ke hui pū me ka methotrexate ma ke ʻano o 15 mg / wiki a i ʻole.

Kahawai
Ka lāʻau ASKL Hiki ke hoʻohana ʻia i ka wā hāpai ʻoiai inā ʻaʻole pono nā lāʻau ʻē aʻe.
ʻO ka hoʻohana ʻana i ka salicylates i ka mea mua o ka hānau ʻana ma ka hihia o kekahi mau haʻawina o ka maʻi retrospective i pili me ka nui o ka nui o ka malenation congenital (palatoschisis (cleft palate), nā puʻuwai puʻuwai). Eia nō naʻe, me ka hoʻohana lōʻihi ʻana i ka lāʻau lapaʻau ma loko o nā wai hoʻōla ma mua o 150 mg / lā, ua noho haʻahaʻa kēia pilikia: ma muli o kahi noiʻi i hana ʻia ma nā 32,000 mau keiki makuahine, ʻaʻohe hanana i waena o ka hoʻohana ʻana o ka acetylsalicylic acid a me kahi hoʻonui ʻana o ka helu o ka hānau hānau ʻana.
Hiki ke hoʻohana 'ia ka Salicylates i ka mea mua a me ka lua o ka hapo o ka hapai wale nō ma hope o ka loiloi ʻana i ka pae e pili ana i ka hopena. Wahi a nā mea hoʻomaka mua, me ka hoʻohana mau ʻana i ka lāʻau lapaʻau, pono ia e lawe i ka acetylsalicylic acid i loko o kahi pākuʻi aia ma mua o 150 mg / lā.
I loko o ka trimester III o ka hāpai ʻana, ka lawe ʻana i nā koina kiʻekiʻe o ka salicylates (ʻoi aku ma mua o 300 mg / lā) e hiki ai i ka hapai ke hoʻohilahila a hoʻonāwaliwali i nā wā ʻo nā wā o ka hānau ʻana, a hiki nō hoʻi ke alakaʻi i ka maʻi cardiopulmonary (ka wā paʻa o ka ductus arteriosus) i nā keiki.
ʻO ka hoʻohanaʻana i ka acetylsalicylic acid ma loko o nā pulu he nui ma mua o ka hānau ʻana e hiki ke alakaʻi i ka koko intracranial, aemaise i nā pēpē makua mua.

No laila, koe wale nō nā hihia kūikawā i kuhikuhi ʻia e nā maʻi lapaʻau a palaualelo a ʻolua paha e pili ana i ka mālama kūikawā, hoʻohana ʻia ka acetylsalicylic acid i ka wā o ke kolamu o ka wā hope loa.
ʻO ka Acetylsalicylic acid a me kāna mau metabolites i nā liʻiliʻi liʻiliʻi e hoʻopili ʻia i ka umauma waiū o nā wahine lactating. I kēia manawa, me ka hoʻohana pōkole pōkole o nā salicylates e nā makuahine, ʻaʻole i hoʻokumu ʻia ka hoʻomaka ʻana o nā hopena e pono ai i nā keiki hānai umauma, me ke ʻano he kānāwai, ʻaʻohe pono o ka ho'ēmi i ka hānai umauma. Eia nō naʻe, ma ka hana o ka hoʻohana mau ʻana i nā papa kiʻekiʻe o ka acetylsalicylic acid, pono e hoʻokaʻawale ka pale umauma.

Hoʻopili ʻana me nā lāʻau lapaʻau ʻē aʻe:
ʻO ka hoʻohana ʻana i ka waikehiwa acetylsalicylic i ka manawa like me ka methotrexate ma nā inika o 15 mg / wiki a me ke ʻano he contraindicated ma muli o ka hoʻonui ʻana o ka pakanā hematological o methotrexate (hoʻemi i ka wehe ʻana o ka renal cleotce o ka methotrexate me nā mea hana anti-inflammatory a me ka haʻalele o ka methotrexate me nā salicylates ma muli o nā protein plasma).
Hoʻohana ʻia e hui me ka akahele:
- ke hoʻohana me methotrexate i nā haʻahaʻa o ka haʻahaʻa ma lalo o 15 mg / wiki e hoʻonui i ka pakano hematological o methotrexate (hoʻemi i ka wehe ʻana o ka renalrexate me nā mea hana anti-inflammatory a me ka haʻalele o ka methotrexate me nā salicylates mai ka pilina me nā protein plasma).
- ke hoʻohana like ʻole o ka ibuprofen pale i ka hoʻopaʻa ʻana ʻole o nā platelets e ka acetylsalicylic acid. Hoʻopili i ka maʻi Ibuprofen no nā maʻi e hōʻeha i ka maʻi cardiovascular e kaupalena i ka hopena cardioprotective o ka acetylsalicylic acid.
- me ka hoʻohana pū ʻana o ka lāʻau a me nā anticoagulants, piʻi ka nui o ke koko. Me ka hoʻohana pū ʻana o ka nui o ka salicylates me nā NSAIDs (ma muli o ke ʻano like o ka hopena), ʻoi ka piʻi ʻana o nā ʻeha a me ke koko gastrointestinal.
- ka hoʻohana pū ʻana me nā ʻaina uricosuric, e like me ka benzobromaron, probenecid, e hōʻemi ana i ka hopena o ka ʻōmaʻomaʻi uric acid (ma muli o ka hoʻokūkū no ka hōʻaho ʻana i ka waʻa uric e nā tubula renal).
- me ka hoʻohana pū ʻana me ka digoxin, ke piʻi nui o ka ʻai o nā mea i loko o ke kōʻai koko ma muli o ka emi ʻana o ka hana i loko o ka renal.
- me ka hana like ʻana o nā wai kiʻekiʻe o ka acetylsalicylic acid a me ka hoʻoliʻi antidiabetic waha mai ka hui o sulfonylurea a i ʻole derivatives insulin, e hoʻonui ʻia ka hopena hypoglycemic o ka hopena ma muli o ka hopena hypoglycemic o ka acetylsalicylic acid a me ka wehe i ka sulfonylurea e pili ana i nā protein plasma.
- ka diuretics i hui pū me nā kiʻekiʻe kiʻekiʻe o ka acetylsalicylic acid e hōʻemi ana i ka kānana glomerular ma muli o kahi kaohiʻana o ka syntaglandin synthes i loko o nā keiki.
- nā glucocorticosteroids systemic (me ke kaila o ka hydrocortisone) i hoʻohana ʻia no ka huli ʻana no ka maʻi o Addison ma ke ʻano me ka corticosteroids e hōʻemi i ka pae o ka salicylates i ke koko a hoʻonui i ka pilikia o ka overdose ma hope o ka mālama ʻana.

I ka manawa e hoʻohana ai me ka corticosteroids, hoʻonui ka nui o ka hoʻomohala ʻana i ke koko gastrointestinal.
- nā selotonin selecton reuptake i hoʻohui ʻia: hoʻonui nui i ka kahe mai ke kī ʻana mai i ke kīpē o luna o ka gastrointestinal ma muli o ka hiki o ka hopena synergistic.
- ʻO ACE inhibitors (ACE) i hui pū me nā koina kiʻekiʻe o ka acetylsalicylic acid e hoʻoulu ai i ka emi ʻana o ka kānana glomerular ma muli o ka hoʻokuʻu ʻana i nā prostaglandins vasodilator a me kahi hoʻēmi i ka hopena antihypertensive.
- me ka hoʻohana like ʻana me ka waila valproic, acetylsalicylic acid e haʻalele iā ia mai kona pili me nā protein plasma, e hoʻonui ana i ka maʻi o ka hope.
Hāʻawi ka Ethyl ʻalika i ka hōʻino i ka membous mucous o ka gastrointestinal tract a hoʻolōʻihi i ka manawa hoʻokahe ma muli o ka synergism o ka acetylsalicylic acid a me ka waiʻona.

Ke keu
Hiki ke kau ʻia ka nui o ka salicylates ma muli o ka lilo ʻana o ka maʻi hopohopo e hiki mai ana i ka hoʻomehana lōʻihi, a mai ke kao hoʻohuihua, ʻo ia ka mea e hoʻoweliweli ʻana i ke ola (overdose), a he kumu ia no ka hana kuhi hewa ʻana e nā keiki a i ʻole overdose hiki ʻole.
ʻO nā hōʻailona mua o ka hoʻobala me ka acetylsalicylic acid he dizziness, nausea, luaʻi, tinnitus a me ka wikiwiki wikiwiki, hōʻemi. Ua nānā ʻia nā hōʻailona ʻē aʻe: ka lohe ʻana, hōʻeha i ka ʻike, hōʻehaʻeha, hoʻonui ʻia, ka holo ʻana o ka mīkini, ka ʻalū a me ka coma, nā palapa, hyperthermia, nāʻauʻau. Hiki ke hūnā ʻia nā maʻi laikini salicylate, no ka mea he mau nonspecific kāna mau hōʻailona.
I ka loaʻa ʻana o kahi nui o ka lāʻau lapaʻau ma mua o ka mea i ʻōlelo ʻia ʻia, pono e kūkā koke ʻoe i kekahi kauka, a inā i loaʻa ka maʻi o ka maʻi, e hele koke ʻoe i ka haukapila.
ʻO kahi overdose o ka lāʻau i ka poʻe maʻi makua a i nā kamaliʻi liʻiliʻi (e lawe nui ana i nā ʻoihana i ʻōlelo ʻia ai a i ʻole nā mea make ʻole) e koi nui ʻia, no ka mea i loko o kēia mau pūʻulu o nā maʻi ke alakaʻi i ka make.
Ma ka hoʻohālikelike nuiʻole, hoʻopiʻi ka paleʻana i ka acid-base a me ke kaulike-wai-electrolyte (ka metabolic acidosis a me ka liʻiliʻi o ka wai).
ʻAʻohe mea antidote kikoʻī.

Wahi mālama:
Store i kahi e pale ʻia mai ka lepo a me ka mālamalama ma kahi wela ʻaʻole eʻoi aku ma mua o 25 ° C.
Mai mālama i nā keiki.

Kuhi puka:
ASA - nā pākuʻi coal enteric, 75 mg a me 150 mg.
Ke kuhi nei: 10 a 15 mau papa i nā palaka. Ekolu, elima a ʻeono paha i nā pōpō palaka o 10 mau papa pākahi, me nā ʻōkuhi no ka hoʻohana ʻana i loko o kahi ʻeke pepa.
ʻEono papa ʻaila pā 15 o kēlā me kēia, me nā ʻōkuhi no ka hoʻohana ʻana i kahi kāʻele pepa.

Kūkulu:
1 papaASKL aia ka mea e ola ai: acetylsalicylic acid - 75 mg a i ʻole 150 mg.
Nā mea kūlike: kaʻaila palaoa, crospovidone (polyplasdone XL-10), talc, cellulose microcrystalline.
Ka hana nīlī: Advant Preished (hydroxypropyl methylcellulose, copovidone, polydextrose, propylene glycol, medium chain triglycerides, titanium dioxide, yellow iron oxide), Advantia Performance® (methacrylic acid-ethyl acrylate copolymer, talc, titanium dioxide, triethyl yellowite orange , ʻoliʻoli ʻoliʻoli E 129).

Kau koho:
Ka lāʻau ASKL hoʻohana me ka makaʻala i ka hopena o: hypersensitivity i ka analgesic, anti-inflammatory, antirheumatic drug, a me ka keʻa ʻana o nā maʻi kūlohelohe i nā ʻano mea ʻē aʻe, ʻeha o ka gastrointestinal, a me ka mōʻaukala o ke kūaloko a me ka hana pinepine a i ʻole ka gastrointestinal, ka hoʻohana pinepine ʻana o anticoagulants, hana renal i ʻole a me / aʻai ʻole.
I ka hihia o ka hoʻohana ʻana i ka lāʻau lapaʻau, pono i ka mea maʻi e nīnau i ke kauka ma mua o ka lawe ʻana i ka ibuprofen.
I nā mea maʻi me nā maʻi hoʻopalapula, me ka hoʻohuihui bronchial, rhinitis allergic, urticaria, ʻehaʻeha o ke kino, ka huhui o ka membrane a me ka polyposis nasal, a me ka hui pū me nā maʻi ʻeha a me nā maʻi i nā maʻi me ka hypersensitivity i nā NSAID e mālama ʻia me ka acetylsalicylic acid ka hoʻomohala ʻia paha o ka hoʻomohala ʻana o ka bronchospasm a i ʻole he hoʻouka kaua o ka bronchial asthma. I nā hana hoʻokele (me ka manuahi), ʻo ka hoʻohana ʻana o ka hoʻomākaukau e loaʻa ana ka acetylsalicylic acid e hiki ke hoʻonui i ka hopena o ke kahe. Me nā liʻiliʻi liʻiliʻi o ka acetylsalicylic acid, e hōʻemi ʻia nā ʻenekia hoʻōla uric. Hiki i kēia ke alakaʻi i ka maʻi gout i nā mea maʻi me ka hoʻohaʻahaʻa ʻana i ka hoʻōho uric acid.
I ka wā o ka mālama ʻana me ka acetylsalicylic acid, ʻaʻole pono e inu i ka wai ʻawa, hāʻawi ʻia i ka nui o ka hōʻino o ka pōʻino o ka membrane mucous o ka gastrointestinal tract.
Mai hoʻohana i nā lāʻau lapaʻau e pili ana i ka acetylsalicylic acid no nā keiki me ka maʻi maʻi respiratory viral maʻi (ARVI), ka mea i hui pū ʻia a ʻaʻole i hele pū ʻia me ka piʻi ʻana o ke ʻano wela o ke kino. No kekahi mau maʻi maʻi, ka maʻi influenza A, ka maʻi influenza B a me ka hua manu, e pili ana i ka hoʻomohala ʻana i ka maʻi Reye, kahi maʻi koʻikoʻi loa ia akā e lohi ana i ka ola e koi ai i ka mālama olakino. Hiki ke hoʻonui ʻia ka hopena inā e hoʻāla ʻia ka acetylsalicylic acid e like me ka lāʻau lapaʻau concomitant, akā ʻaʻole i hōʻike ʻia ka pilina kumu ma kēia hihia. Inā hele pū ʻia kēia mau kūlana me ka hoʻomau ʻana i luna, ʻo ia paha ke hōʻailona o ka maʻi o Reye. Hāʻawi ʻia i nā kumu i luna, nā keiki ma lalo o ka 16 makahiki o ka wā e contraindicated i ka hoʻohana ʻana i ka lāʻau me ka ʻole o nā hōʻailona kūikawā (maʻi ʻo Kawasaki).
Hoʻokomo i ka hiki ke lawe i nā kaʻa a kāohi i nā mīkini
ʻAʻole pili ka ASA i ka hiki ke hoʻokele i nā kaʻa a kāohi i nā mīkini.

E hoʻokuʻu i ke ʻano a me ka ʻano

Loaʻa ka ASK-cardio i ke ʻano o nā papa i komo i ka enteric: biconvex, ka pōʻai, ke keʻokeʻo (10 mau ʻāpana i blister, i loko o kahi pahu pahu pahu o 1, 2, 3, 5, 6 a i ʻole 10 mau pā, 30, 50, 60 a i ʻole 100 papa i nā kēla polymer, i loko o kahi pūpū pepa 1 hiki).

Helu 1 papa:

mea waiwai: acetylsalicylic acid (ASA) - 100 mg,
Nā mea kōkua: nā māla huaʻai, ka stearic acid, lactose monohala, talc, polyvinylpyrrolidone,
kānana enteric: macrogol 6000, titanium dioxide, talc, kahi copolymer o ka methacrylic acid a me ka ethacrylate.

Nā hōʻailona no ka hoʻohana ʻana

ka lani panghina,
ka pale ʻana o nā ulia cerebrovascular transient,
ka pale ʻana i ka thromboembolism o ka pulima pulmonary a me kāna mau lālā, a me ka thrombosis vein hohonu (no ka laʻana, me ka immobility no ka manawa lōʻihi ma muli o kahi hana hōʻeha koʻikoʻi).
pale ʻana i ka huakaʻi (me i nā mea maʻi me ka maʻi cerebrovascular transient)
ka pale ʻana o ka maʻi myocardial akala i ka wā i hoʻopiʻi ai i kekahi o nā mea hou aku paha (ʻo ka hypertension arterial, diabetes mellitus, obesity, hyperlipidemia, ʻelemakule, ulaula), pale ʻia o myocardial infarction,
ka pale ʻana o ka thromboembolism ma hope o ka invasive a me ka vascular surgery (e.g. arteriovenous bypass, coronary artery bypass grafting, carotid artery angioplasty, carotid artery endarterectomy).

Nā Hoʻohui

uhaiki pohihihi
pilikia kaumaha ʻole
Diorrosis hemorrhagic (von Willebrand maʻi, hypoproteinemia, thrombocytopenic purpura, hemophilia, telangiectasia, thrombocytopenia),
hana paʻa pilikia III-IV hana papa,
ka huhū haole,
ka hoʻonāukiuki ʻana o nā pilikia o erosive a me ka ulcerative o ka ʻili o ka gastrointestinal,
lactase kakali, lactose intolerance, glucose-galactose malabsorption syndrome,
ʻO ka palaka bronchial i hopena mai i ka hoʻohana ʻana i nā lāʻau anti-inflammatory non-steroidal a me salicylates, kahi hui pū ʻana o ka polyposis hoʻi hou o nā sinus paranasal a me ka ihu, ka palaualelo bronchial a me hypersensitivity i ASA.
wā hapai (mua a me nā kolu ʻoi aku ʻoi)
umauma umauma,
na keiki a me na opio malalo o na makahiki 18
hoʻohana me ka methotrexate i loko o hoʻokahi pule hebedoma he 15 mg a i ʻole,
mahuahua i kēlā me kēia kanaka i kekahi o nā mea pono o ka lāʻau a me nā mea kanu non-steroidal a me nā anti-inflammatory.

Hoʻohana ʻia (ASK-cardio me ka akahele):

mālie i ke'ōpū hema ʻole,
mālie i ke'ōleʻa pale ʻole,
nā maʻi hanu maʻi,
ʻOiaʻiʻo
ka mōʻaukala o ke kaila gastrointestinal a i ʻole ulcerative lesi o ka digestive tract,
polyposis o ka ihu,
huhū maʻi
pālahalaha maʻi
kohola
Ka hapa ʻoliki K
Allergy allergy
nā hoʻopiʻi nui o ka glucose-6-phosphate dehydrogenase,
wā hapalua (lua trimester),
holomua holomua
ka manawa like me kekahi mau lāʻau lapaʻau (me antiplatelet, anticoagulant, a i ʻole nā ʻemuna thrombolytic, ibuprofen, digoxin, methotrexate (ma kahi hebedoma he haʻahaʻa ma mua o 15 mg), ka waila valproic, nā selotonin reuptake selektif, nā derivatives waikiki salicylic, no nā inika kiʻekiʻe) ka waha a me ka insulin, nā lāʻau anti-inflammatory non-steroidal a me ka inu wai).

ʻLoe a me ke kākele

ʻO kā cardA ASA i lawe ʻia ma ke ʻano o ka ʻai ʻana. ʻAʻole ʻōwapa ʻia ka papa papa, holoi ʻia me ka nui o nā wai.

Hoʻoholo ʻia ka lōʻihi o ka hopena e ke kauka hele mai. E like me ka punawai antiplatelet, lawe ʻia ka lāʻau lapaʻau no ka manawa lōʻihi.

Wahi paipai:

ka pale ʻana i ka maʻi myocardial akela (inā i manaʻo ʻia ka hoʻomohala ʻana): nā ʻomina mua he 100-300 mg, pono pono e lawe ʻia ka lāʻau lapaʻau ma hope o ka kānalua o ka hoʻomohala ʻana i ka hanana myocardial infarction (no ka wikiwiki o ka hoʻopili ʻana, e ʻoki ʻia ka papa mua o ka lāʻau). ʻO ka dosis mālama ma hope o ka hoʻomohala ʻana o ka infarction myocardial he 200-300 mg i hoʻokahi lā no 30 lā,
ka pale ʻana i ka maʻi myocardial akakei i hōʻea no ka manawa mua (i mua o nā pilikia pākuʻi): 100 mg hoʻokahi i ka lā a 300 mau lā i kekahi lā,
ka pale ʻana o ka embolism pulmonary a me kāna mau lālā, a me ka thrombosis vein hohonu: 100-200 mg i kēlā me kēia lā a 300 mg o kēlā me kēia lā.
nā hōʻailona ʻē aʻe: 100-300 mg i kēlā me kēia lā.

Nā hopena hopena

pānaʻi hana: ʻoi loa - ka helehelena, ka lua, ke ʻeha ma ka ʻōpū, ka puʻuwai, ʻokoʻa - kahe ʻana mai ka ʻeha o ka gastrointestinal, nā ʻōpū duodenal a me ka ʻōpū (a me ka perforated), hoʻonui i ka hana hepatic transaminases (transient).
cardiovascular system: hiki i ʻole - huehue i nā wāwae, hoʻonui i nā hōʻailona o ka puʻuwai naʻau ʻole,
hematopoietic ʻōnaehana: intra- a me ka pehu kūpono postoperative, ke kahe huaka, hematomas, kahe koko mai ka genitourinary tract, nosebleeds, hemorrhage i loko o ka lolo, ka maʻi a me ka palupū paha o ka posthemorrhagic / hao hao anemia, i nā mea maʻi me ka maʻi glucose-6-phosphate dehydrogenase hemolisis
kikowaena kikowaena kikowaena: tinnitus, hearing loss, puhi,
ʻōnaehana urinary: hana renal functioning, kaulike ʻole o ka renal,
nā maʻi kūlohelohe: bronchospasm, ʻehaʻeha a me ke kauliki, rhinitis, urticaria, cardio-respiratory syndrome syndrome, Quincke edema, ka huehue o ka mucosa nasal, ka pīhoihoi anaphylactic.

Nā ʻōlelo kikoʻī

Pono nā lāʻau ASK-cardio ke hoʻohana wale ʻia e ke kuhikuhi e ke kauka.

Ma nā haʻahaʻa haʻahaʻa, hiki i ka ASA ke hōʻeha i ka maʻi gout i nā mea maʻi hiki.

ʻO nā hopena nui o ka lāʻau ke hopena i ka hopena hypoglycemic, pono e noʻonoʻo ʻia i ka wā e koho ai i ka ASA i nā poʻe maʻi me ka maʻi mellitus e loaʻa ana i ka insulin a i nā lāʻau hypoglycemic waha.

Inā nui aʻe ka nui o ka ʻai ʻana o ASK-cardio, ʻo ka hoʻonui ʻana o ke ake o ke ake ʻana o ke koko gastrointestinal.

I nā poʻe maʻi maʻi, ʻoi loa ka nui o ka lāʻau.

I ka wā o ka mālama ʻana, pono e mālama ʻia i ka hana a ke hoʻokō nei i nā hana e pili ana i ka piʻiʻana o ka nānā nui a me ke ʻano wikiwiki (holo i ke kaʻa, ka hana a ka mea hana a me ka dispatcher, me kekahi mea).

Hoʻohui nūhou

Me ka hoʻohana like pū ʻana o ASA-cardio, e hoʻonui ana i ka hopena therapeutic a me nā hopena ʻaoʻao o nā lāʻau lapaʻau e pili ana: methotrexate, thrombolytic, antiplatelet and anticoagulant agents, selective serotonin reuptake inhibitors, digoxin, insulin a me ka waha hypoglycemic aelike, valproic acid, salicylate a isosporolitol . ^ E Ha yM. Inā e hoʻohana i ka ASA i ka manawa like me nā lālani i hōʻike ʻia, pono ia e noʻonoʻo i ka hoʻēmi ʻana i kā lākou dosis.

I ka wā e hoʻohana pū ai me nā ʻōmole kiʻekiʻe, nā ASA-cardio palupalu i nā hopena therapeutic o nā lāʻau lapaʻau e pili ana: kekahi diuretics, angiotensin-hoʻohuli i ka hoʻohiolima o ka huina, ʻaia uricosuric (probenecid, benzbromarone), glucocorticosteroids systemic (me ke ʻano o ka hydrocortisone, i hoʻohana ʻia no ka hoʻololi hou ʻana o nā maʻi o Addison). Inā pono e hoʻohana i ka ASA me nā lālani i hōʻike ʻia, pono ia e noʻonoʻo i ke kumu o ka hoʻoponopono hoʻoponopono ʻia.

ʻO nā hoʻomākaukau e hoʻomākaukau ana acetylsalicylic acid

ʻLoe a me ke kākele

ʻO kā cardA ASA i lawe ʻia ma ke ʻano o ka ʻai ʻana. ʻAʻole ʻōwapa ʻia ka papa papa, holoi ʻia me ka nui o nā wai.

Hoʻoholo ʻia ka lōʻihi o ka hopena e ke kauka hele mai. E like me ka punawai antiplatelet, lawe ʻia ka lāʻau lapaʻau no ka manawa lōʻihi.

Wahi paipai:

ka pale ʻana i ka maʻi myocardial akela (inā i manaʻo ʻia ka hoʻomohala ʻana): nā ʻomina mua he 100-300 mg, pono pono e lawe ʻia ka lāʻau lapaʻau ma hope o ka kānalua o ka hoʻomohala ʻana i ka hanana myocardial infarction (no ka wikiwiki o ka hoʻopili ʻana, e ʻoki ʻia ka papa mua o ka lāʻau). ʻO ka dosis mālama ma hope o ka hoʻomohala ʻana o ka infarction myocardial he 200-300 mg i hoʻokahi lā no 30 lā,
ka pale ʻana i ka maʻi myocardial akakei i hōʻea no ka manawa mua (i mua o nā pilikia pākuʻi): 100 mg hoʻokahi i ka lā a 300 mau lā i kekahi lā,
ka pale ʻana o ka embolism pulmonary a me kāna mau lālā, a me ka thrombosis vein hohonu: 100-200 mg i kēlā me kēia lā a 300 mg o kēlā me kēia lā.
nā hōʻailona ʻē aʻe: 100-300 mg i kēlā me kēia lā.

Angina hiki ole,
ka pale ʻana o nā ulia cerebrovascular transient,
ka pale ʻana i ka thromboembolism o ka pulima pulmonary a me kāna mau lālā, a me ka thrombosis vein hohonu (no ka laʻana, me ka immobility no ka manawa lōʻihi ma muli o kahi hana hōʻeha koʻikoʻi).
pale ʻana i ka huakaʻi (me i nā mea maʻi me ka maʻi cerebrovascular transient)
ka pale ʻana o ka maʻi myocardial akala i ka wā i hoʻopiʻi ai i kekahi o nā mea hou aku paha (ʻo ka hypertension arterial, diabetes mellitus, obesity, hyperlipidemia, ʻelemakule, ulaula), pale ʻia o myocardial infarction,
ka pale ʻana o ka thromboembolism ma hope o ka invasive a me ka vascular surgery (e.g. arteriovenous bypass, coronary artery bypass grafting, carotid artery angioplasty, carotid artery endarterectomy).

Loaʻa ka hopena

ʻŌnaehana nenoaiu: ka manawa pinepine - ka luaʻi, nilo, ka ʻeha ma ka ʻōpū, ka puʻuwai, ʻokoʻa - kahe ʻana o ka ʻōpū o gastrointestinal, ʻōpū duodenal a me ka ʻōpū (me ka perforated), hoʻonui i ka hana he transaticases hepatic (transient).

ʻŌnaehana Cardiovascular: jarang - kaʻe ʻana o nā wāwae, hoʻonui i nā hōʻailona o ka hiki ʻole o ka naʻau puʻuwai.

ʻŌnaehana Hematopoietic: intra- a me ka luʻu postoperative, ke kahe koko, hematomas, kahe koko mai ka genitourinary tract, nosebleeds, hemorrhages i loko o ka lolo, aʻeha a i ʻole post-hemorrhagic / iron deficiency anemia, i loko o nā mea maʻi me ka hōʻemi kino-6-phosphate dehydrogenase deficiency - hemolytic anemia a.

Pūnaehana pīhoihoi waena: tinnitus, hoʻolohe luhi, dizziness.

ʻŌnaehana papa maʻi: hana renal impaired, hoʻomaʻemaʻe renal.

Allergic hopena pili: bronchospasm, ʻehaʻeha a me ka ʻōpala, rhinitis, urticaria, cardio-respiratory syndrome syndrome, hoʻopuka ʻo Quincke, ka huehue o ka mucosa nasal, ka hopena anaphylactic.

Ke keu

ʻO nā hōʻailona o kahi overdose o ka hōʻeha maʻalahi: ka nausea, luaʻi, tinnitus, lohe kaumaha, dizziness, confing.
Hoʻolālā: hoʻemi hōʻemi.

Nā hōʻailona o kahi overdose koʻikoʻia: ka hānai, ka hyperventilation, ketoacidosis, respal alkalosis, coma, cardiovascular a me ka hanu weliweli, hypoglycemia koʻikoʻi.
Hoʻomaʻamaʻa: nā hoʻokipa koke i nā keʻena loea no ka mālama ʻana i ka maʻi ulia - ʻo ka gastric lavage, ka hoʻoholo ʻana i ke kaulike ʻana o ka acid-base, alkaline a me nā diuresis alkaline paʻa, hemodialysis, ka hoʻoponopono o nā mea hoʻoponopono, hoʻāla i hana ʻia, ʻāhaʻomaʻo.

Hoʻohui ka nui o nā makehe o ka ASA me ka hopena o ke koko gastrointestinal. Hoʻokomo koʻikoʻi ka overdose i nā maʻi maʻi.

Kāleka i kēlā me kēia 1 papa:

mea waiwai: acetylsalicylic acid 100 mg,
nā mea hoʻowalewale:
ʻĀina: lactose monohydrate (waiū waiū) 15.87 mg, povidone (polyvinyl pyrrolidone) 0.16 mg, pāhu uhu 3.57 mg, talc 0.2 mg, waihā stearic 0.2 mg
ʻili: Methacrylic acid a me ka ethacrylate copolymer 1: 1 (colicoate MAE 100) 4.186 mg, macrogol-6000 (kiʻekiʻe kiʻekiʻe molekole polyethylene glycol) 0.558 mg, talc 1.117 mg, titanium dioxide 0.139 mg.

nā papa āpau biconvex, i ulana ʻia me ka ʻapo keʻokeʻo. Ke keʻokeʻo ka ʻaoʻao o ke kumu.

Hoʻolaha hui:

Lapaʻau lāʻau
ʻO ka acetylsalicylic acid (ASA) kahi salicylic acid ester, nona nā pūʻulu o nā lāʻau anti-inflammatory non-steroidal (NSAIDs). Hoʻokumu ka hana 'ana i ka hana i ka hiki ʻole ke hoʻoneʻe ʻia o ka enzyme cyclooxygenase (COX-1), ma muli o ke ʻano o ka hoʻokaʻawale ʻana i nā prostaglandins, prostacyclins a me thromboxane i pāpā ʻia. Hoʻemi i ka hoʻohui, plathes adhesion a me ka thrombosis e ka pale ʻana i ke kūmole o ka thromboxane A₂ i loko o nā pelele. Hoʻonui ia i ka hana fibrinolytic o ke koko koko a hōʻemi i ka hoʻoliʻiliʻi ʻana o nā huaʻala coagulation depend-bit K (II, VII, IX, X). Hoʻomohala ka hopena antiplatelet ma hope o ka hoʻohana ʻia ʻana o nā pona liʻiliʻi o ka lālani a hoʻomau no 7 mau lā ma hope o hoʻokahi pae. ʻO kēia mau hiʻohiʻona o ka ASA e hoʻohana i ka pale a me ka mālama ʻana i ka infococote myocardial, maʻi maʻi coronary, nā ʻōmole o ka maʻi varicose. ʻO ASA i nā inikini kiʻekiʻe (ʻoi aku ma mua o 300 mg) kahi hopena anti-inflammatory, antipyretic a me nā analgesic.

Lapaʻau lāʻau
Ma hope o ka lawelawe waha, ASA wikiwiki a hoʻoulu maoli ʻia mai ka gastrointestinal tract (GIT). Ua hoʻokaʻawale ʻia ka ASA i ka wā o ke kō. I ka wā a ma hope o ke kō ʻana, ua huli ka ASA i ka metabolite nui - ka salicylic acid, ka mea i hōʻiliʻili ʻia i ka nui o ka ate ma ka ʻano o ka hoʻoulu ʻana o nā enzymes me ka hoʻokumu ʻana o nā metabolites e like me ka phenyl salicylate, glucuronide salicylate a me ka salicyluric acid, ka mea i loaʻa i loko o ka nui o nā koena a ma ka urine. I nā wahine, ʻoi aku ka luhi o ka metabolic (ʻoi aku ka liʻiliʻi o ka hana o nā enzymes i loko o ka serum koko). ʻO ka nui loa o ka ʻā o ASA i loko o ke koko koko e loaʻa ana i 10-20 mau minuke ma hope o ka nānā ʻana, ka waikona salicylic - ma hope o 0.3-2 hola. Ma muli o ke kuhi ʻana o nā papa me kahi pūloi pale-aea, hoʻokuʻu ʻia ka ASA i loko o ka ʻōpū (ʻo ka pūpū kūpono e hoʻokaʻawale nei i ka hoʻopau ʻia ʻana o ka lāʻau i loko o ka ʻōpū), akā ma ka ʻano alkaline o ka duodenum. No laila, ʻo ka hoʻopili ʻana o ka ASA i ka puka dosage, nā tablet i hoʻopuni ʻia enteric, co-film, lohi ʻia i ka 3-6 hola hoʻohālikelike ʻia me nā papa maʻamau (me ka ʻole o ia pani).
Hoʻopili nuiʻo ASA a me ka salicylic acid i nā protein plasma (mai ka 66% a i ka 98% hilinaʻi i ka waiū) a ke hoʻolele koke ʻia i ke kino. E kūkaʻe ana ka waikawa Salicylic i ka plasenta a hūnā ʻia me ka waiū umauma.
ʻO ka hoʻōla ʻana o ka salicylic acid ka mea i hilinaʻi ʻia ma muli o ka hopena, ʻo ka mea palena o kona metabolism ma o nā hiki o ka pūnaehana enzymatic. ʻO ka hapalua ola mai nā hola 2-3 i ka wā e hoʻohana ai i ka ASA i nā haʻahaʻa haʻahaʻa a hiki i nā hola 15 i ka wā e hoʻohana ai i ka lāʻau lapaʻau i nā kiʻekiʻe kiʻekiʻe (ʻo nā mana maʻamau o ka acetylsalicylic acid ma ke ʻano he analgesic). ʻAʻole like me nā salicylates ʻē aʻe, me ka hoʻokele mau ʻana i ka lāʻau, ʻaʻole i hōʻuluʻulu ʻia ka ASA i ka serum koko. Hoʻopiliʻia nā lāʻau salicylic a me nā metabolites e nā keiki. I nā mea maʻi me ka hana renal maʻamau, ʻo 80-100% o hoʻokahi pākahi o ke kala e hoʻopili ʻia e nā keiki ma loko o 24-72 mau hola.

Nā hōʻailona no ka hoʻohana ʻana

ka lani panghina,
nani kaina pectoris,
ka mua o ka mālama ʻana i ka maʻi myocardial acute i mua o nā mea iʻike ʻia (no ka laʻana, ka maʻi diabetes mellitus, hyperlipidemia, hypertension, obesity, ulaula, ʻelemakule) a me ka myocardial infarction,
ka pale ʻana o ka stroke ischemic (me nā mea maʻi i ka maʻi cerebrovascular transient).
ka pale ʻana o nā ulia cerebrovascular transient,
ka pale ʻana o ka thromboembolism ma hope o ka hoʻokolohua a me ka wawao ʻana i ka maʻi vascular (e.g. coronary artery bypass grafting, carotid artery endarterectomy, arteriovenous shunting, carotid artery angioplasty).
ka pale ʻana o ka trombosis vein hohonu a me ka thromboembolism o nā pulmonary pulmonary a me nā lālā ona (no ka laʻana, me ka lōʻihi o ka immobilization ma muli o kahi ʻano lawena nui).

Hoʻohana i ka wā hāpai a i ka wā o ka umauma

Hoʻohana ʻia ka hoʻohana ʻana i ka lāʻau i ka wā hāpai (I a me III trimesters) a ma ka umauma. ʻO ka hoʻohana nui ʻana o nā huaʻai he nui o ka salicylates i loko o ka 3 mau mahina o ka hāpai ʻana i pili pū kekahi me ka nui o ka piʻi ʻana o nā maʻi o ka hoʻouluʻana o ka maʻi (split palate, defects heart). I ka lua o ka wā hapalua o ka hapai ʻana, hiki ke kuhikuhi ʻia nā salicylates me ka nānā wale ʻia o ka hōʻemi a me ka pono.
I ka trimester hope loa o ka hāpai ʻana, ka salicylates ma kahi kiʻekiʻe nui (ʻoi aku ma mua o 300 mg / lā) e hoʻonāwaliwali ana i ka hana, ʻoi loa ka pani ʻana o ka ductus arteriosus i loko o ka pūpū, hoʻonui nui ʻia ka huhū ma ka makuahine a me ka maʻi fetus, a me ka hoʻokele ma mua o ka hānau ʻana ma muli o ka wā o ka hemorrhage intracranial, aemaise i nā pēpē ma mua. ʻO ke koho ʻana o nā salicylates i ka mea i pau i ka hana ma hope.
ʻO Salicylates a me kā lākou metabolites i loko o nā liʻiliʻi liʻiliʻi e komo i loko o ka waiū umauma. ʻAʻohe komo o ka salicylates i ka wā o ka umauma i mālama ʻia e ka hoʻomohala ʻana i nā hopena maikaʻi loa i ka pēpē a ʻaʻole pono e pau ka hana ʻana. Eia nō naʻe, me ka hoʻohana mau ʻana o ka lāʻau lapaʻau a i ʻole ke koho ʻana i kahi papa kiʻekiʻe, pono ke hoʻopau koke ka mālama ʻana i ka umauma.

Nā hoʻoponopono Dosage, ke ala o ka hoʻokele

Pono e lawe ʻia i ka ASA-cardio® ma mua, ʻoi aku ka mua o ka ʻai ʻana, me ka ʻole o ka huki ʻana, inu ka wai nui.
Kuhi ʻia ʻo ASK-cardio® no ka hoʻohana lōʻihi. Hoʻoholo ʻia ka lōʻihi o ka hopena e ke kauka hele mai. Ke hala ʻole o nā mea ʻē aʻe, ua ʻōlelo ʻia e nānā i nā hoʻoponopono kaukaʻi aʻe:
Angina ka lōʻihi (me ka ʻaihue ʻaʻinale myocardial infarction) ka palena mua o 100-300 mg (pono e ʻānai ʻia ka papa ʻaina mua no ka hoʻomoana wikiwiki) pono e nā mea maʻi e hiki koke loa ma hope, aia ma hope o ke kānalua o ka hoʻomohala ʻana o ka maʻi myocardial acute. I nā lā 30 aʻe e hala ma hope o ka hoʻomohala ʻana o ka infarction myocardial, pono ke mālama ʻia i kahi pae o 200-300 mg i kēlā me kēia lā.
ʻO ka pale mua a ka lāʻau myocardial infarction ma mua o nā mea pōpilikia 100 mg i ka lā a i ʻole 300 mg i kēlā me kēia lā.
Kākoʻo o ka myocardial infarction. Pūnaewele hiki ʻole a paʻa. ʻO ka paleʻana i ka hōʻeha ischemic a me kahi ulia cerebrovascular transient. ʻO ka paleʻana i ka thromboembolism ma hope o ka hoʻomaʻemaʻe a me ka interventive vascular invasive 100-300 mg i kēlā me kēia lā.
ʻO ka paleʻana i ka thrombosis vein hohonu a me ka thromboembolism o ka artery pulmonary a me kāna mau lālā 100-200 mg i kēlā me kēia lā aiʻole 300 mg o kēlā me kēia lā.

Hoʻopili pū me nā lāʻau ʻē aʻe

Me ka hoʻohana pū ʻana o ASA i ka hana o kēia mau lāʻau, inā pono, e noʻonoʻo pono ka hoʻohana ʻana o ASA me nā waihona i helu ʻia i ka pono e hoʻemi i ka hopena o nā lāʻau lapaʻau:
- methotrexate, ma muli o ka emi ʻana o ka hoʻomaʻemaʻe wehe a me kona neʻe ʻana mai ka kamaʻilio ʻana me nā protein,
- me ka hoʻohana pū ʻana me nā anticoagulants, nā ʻenehana thrombolytic a me antiplatelet (ticlopidine, clopidogrel), hiki ke loaʻa ka hopena o ke kahe i ka hopena o ka synergism o nā hopena therapeutic nui o nā lāʻau i hoʻohana ʻia.
- me ka hana like me nā lāʻau lapaʻau me ka hopena anticoagulant, thrombolytic a i ʻole ka hopena antiplatelet, he nui ka hoʻonui ʻana i ka hopena pōʻino i ka membrane mukoka o ka gastrointestinal tract,
- ka selot serotonin reuptake inhibitors, hiki iā ia ke alakaʻi i ka hoʻonui nui ʻana o ke koko mai ka gastrointestinal tract (synergism me ASA),
- digoxin, ma muli o ka emi ʻana o kona kūwaho renal, hiki iā ia ke alakaʻi i kahi overdose,
- nā haʻi hypoglycemic no ka hoʻokūkū waha (sulfonylurea derivatives) a me ka insulin ma muli o nā waiwai hypoglycemic o ASA pono i nā haʻahaʻa kiʻekiʻe a me ka neʻe mai o nā derogative sulfonylurea mai ka pilina me nā protein plasma koko,
- me ka hana like me ka wa valproic acid, hoʻonui ʻia kona ʻōhua ma muli o ka neʻe ʻana o kona pili me nā protein plasma koko,
- NSAIDs a me ka derivatives waikawa salicylic i nā koina kiʻekiʻe (hoʻonui ʻoi i ka hopena ulcerogenic a me ke kahe ʻana mai ka gastrointestinal tract ma muli o ka hana synergistic), i ka wā e hoʻohana ʻia me ka ibuprofen, aia ka antagonism e pili ana i ka hoʻoneʻe ʻana o nā platelet e hiki ke hoʻoneʻe ʻia ma muli o ka ASA, e alakaʻi ana i ka hopena o ka hopena cardioprotective ASK,
- Ethanol (hoʻonui i ka ulia o ka pōʻino o ka membous waha o ka gastrointestinal tract a hiki i ka manawa hoʻokaʻawale manawa me ke ʻano o ka hoʻonui ʻana i nā hopena o ka ASA a me ka ethanol),
- Me ka hana like o ka acetylsalicylic acid (ma ke ʻano he antiplatelet agent) a me nā mea hoʻokalolo o nā "kalaka" calcium, ʻoi ka hopena o ke kahe koko,
- I ka wā i hoʻohana pū ʻia ai me nā mākau gula, hiki i ka acetylsalicylic acid e hōʻeha i ka pōʻino i ka ate.

Me ka hoʻohana like ʻana o ASA i nā papa kiʻekiʻe, e hoʻonāukiuki i ka hopena o nā lāʻau lapaʻau i hōʻike ʻia ma lalo nei, inā pono, ʻo ka hoʻokele ʻana o ASA me nā lāʻau i hoʻopaʻa ʻia e noʻonoʻo pono i ka pono o ka hoʻoponopono hoʻoponopono o nā lāʻau lapaʻau i kau ʻia.
- kekahi diuretics (i ka wā i hui pū me ASA i nā koina kiʻekiʻe, aia ka emi ʻana o ka hopena o ka filtration glomerular (GFR) ma muli o ka emi ʻana o ka hoʻoulu ʻana o ka prostaglandins i loko o nā keiki),
- e hoʻohālikelike ana i ka angiotensin e hoʻohuli ana i ka hoʻouluulu (ACE) (kahi hōʻemi i ka hopena o ka nui ma ke ʻano o ka GFR i ʻike ʻia ma muli o ke kaohi ʻana o ka prostaglandins me kahi hopena vasodilating, kēlā me kēia, nā nāwaliwali o ka hopena hypotensive. i kuhikuhi ʻia i nā mea maʻi no ka mālama ʻana i ka puʻuwai o ka puʻuwai paʻakikī.ʻO kēia hopena hoʻi i ka wā i hoʻohana ʻia me ka ASA i ka nui dosis
- nā lāʻau me ka hana uricosuric - benzbromaron, probenecid (hoʻemi i ka hopena uricosuric ma muli o ka hoʻokūkū hoʻokūkū o ka renal tubular urinary acid excretion),
- me ka hoʻohana pū ʻana me ka glucocorticosteroids systemic (ke ʻole o ka hydrocortisone, i hoʻohana ʻia no ka hoʻololi hou ʻana o nā maʻi a Addison), ke piʻi aʻe nei i ke kauā o ka salicylates a, ma muli, i nāwaliwali o kā lākou hana.
ʻO nā antacids e loaʻa ai ka magnesium a me / a i nā alumini lohi e hoʻolohi i ka hoʻopihapiha ʻana o ka acetylsalicylic acid.

Hoʻokomo i ka hiki ke lawe i nā kaʻa, nā mīkini

I ka wā o ka mālama ʻana, pono e hana ʻia ka akahele i ka wā e hana ai i nā hana ʻehaʻeha e pono ai ka nui o ka nānā ʻana a me ka wikiwiki o nā hopena psychomotor (ke kaʻa hoʻokele ʻana, ka hana ʻana me nā hāmeʻa neʻe, nā hana a ka mea hoʻihoʻi a me ka ʻoihana, me nā mea āpau).

E hoʻokuʻu i nā palapala a me ka ʻano

Hāʻawi ʻia ka lāʻau lapaʻau ma ke ʻano o nā papa - ʻaʻole i hoʻolako ka mea hana no nā palapala hana ʻē aʻe. ʻO ke keʻokeʻo o nā papa i ke keʻokeʻo, ua puni ka ʻano, i uhi ʻia me ka membrane e hoʻohemo ai i nā ʻōpū ma hope o ka hoʻokele ʻana.

ʻO ka cardA ASA kahi lāʻau lapaʻau anti-inflammatory non-steroid e loaʻa nā mea hōʻola.

ʻO nā papa i loko o nā polū o 10 mau ʻāpana. Hoʻopili ʻia nā pani ma nā paʻi pepa. No ka ʻoluʻolu o ka mea kūʻai, loaʻa i nā peke he helu helu ʻē aʻe - 1, 2, 3, 5, 6, a i ʻole 10 mau ʻāpana.

Hoʻopili ʻia nā papa i loko o nā kēnā wai o ka polymer. Hāʻawi ka mea hana i nā ipu me kahi mau papa ʻē aʻe - 30, 50, 60 a i ʻole 100 mau ʻāpana.

ʻO ka hopena o ka lāʻau lapaʻau ma muli o ka mea ikaika, ʻo ia ka ASA (acetylsalicylic acid). Aia kēlā me kēia papa i 100 mg. E hoʻomaʻamaʻa i ka hopena therapeutic o nā papa, ua hoʻohui ʻia nā mea hou aku - nā stearic acid, polyvinylpyrrolidone, etc.

Ka hana lāʻau lapaʻau

Ke kope maikaʻi nei ka lāʻau me ka wela, hiki i ka hopena analgesic maikaʻi, hiki ke hoʻokō me ka platelet aggregation. Ma muli o ka heleʻana o ka acetylsalicylic acid i ka hoʻopili ʻana, kōkua ke ola lapaʻau e pale aku i ka hōʻeha a me ka infarction myocardial no nā poʻe e loaʻa nei i ka angina pectoris ka paʻa.

ʻO kahi mea e lawe nei i ka lāʻau lapaʻau no ka pale ʻana e hōʻemi i ka hopena o ka hoʻoulu hou ʻana o nā pathologies cardiovascular. ʻO kahi lāʻau lapaʻau e like me ke prophylactic e hōʻemi i ka pilikia o nā kuʻuna koko.

Lapaʻau lāʻau

No kahi manawa pōkole, hoʻopili ʻia ʻo ASA i piha mai ka gastrointestinal tract, e hoʻohuli ana i ka salicylic acid, ʻo ia ka metabolite nui. E hana ana nā Enzymes i ka waikawa, no laila ua hoʻohālikelike ʻia ka paʻakai, e hana ana i nā metabolites ʻē aʻe, e komo pū ana me ka glucuronide salicylate. Loaʻa nā metabolite i ka urine a me nā pilena kino o ke kino.

ʻO ka ʻike kiʻekiʻe loa o ka hana ikaika i ke koko ua mālama ʻia ma lalo o ka hapalua hola ma hope o ka lawe ʻana i ka paila.

ʻO ka hapalua o ke ola o nā lāʻau lapaʻau e hilinaʻi ʻia i ka lāʻau i lawe ʻia. Inā lawe ʻia ka lāʻau lapaʻau ma nā wahi liʻiliʻi, a laila mau ka manawa o 2-3 mau hola. Ke lawe nei i nā inika nui, hoʻonui ʻia ka manawa i nā hola 10-15.