ʻO ka lāʻau Onglisa mai ka maʻi mellitus maʻi maʻi - kikoʻī kikoʻī kikoʻī no ka hoʻohana

Hoʻopilikia kēia maʻi i ka lā 9% o ka heluna o ka honua. ʻO nā ʻoihana lapaʻau a me nā ʻōnaehana olakino o nā ʻāina alakaʻi o ka honua e hoʻolilo ana i nā piliona kālā, a ua lanakila ka maʻi diabetes a me ka hakakā ʻana a puni ka honua, e lilo ana ka ʻōpio, a lilo i ka paʻakikī.

Ke lawe nei ka maʻi maʻi ma kahi ʻano i manaʻo ʻole ʻia e: ma 2020, hapalua hapelima mau mea maʻi me ka maʻi diabetes type 2 ua wānana ʻia, a ʻaʻole i aʻo nā kauka pehea e hoʻomau pono ai i ka maʻi.

Inā me ka maʻi maʻi type 1, e pili ana i ka emi iho ma lalo o ka 10% o nā maʻi āpau, ua maʻalahi nā mea āpau: hoʻemi i ka kaila o ka glucose i ke kahe koko ma o ke kiʻi ʻana i ka insulin (ʻaʻohe mea ʻē aʻe e hāʻawi ʻia i laila) a maikaʻi nā mea āpau (i kēia lā, no kēlā mau mea maʻi, ua koho pū kekahi i kahi pancreas kūlohelohe. ), a laila me ka diabetes type 2, ʻaʻole holo maikaʻi ke ʻenehana kiʻekiʻe.

Ma ka hoʻohālikelike, no ke ʻano maʻi maʻi 2, ua haʻi ʻia ke kō i ka ʻenemi nui, e hoʻopiha ana i ka mākeke me nā lāʻau lapaʻau haʻahaʻa. ^ E Ha yM. Hoʻonui i ka mālama ʻana i ka maʻi maʻi me ka kōkua o nā lāʻau lapaʻau, a i ʻimi ʻia kekahi lāʻau lapaʻau hou i kekahi lāʻau lapaʻau, a laila hoʻohui ʻia kekahi lāʻau lapaʻau hou i kēia paʻakikī, a hiki i ka huli ʻana o ka insulin.

No 20 mau makahiki i hala aku nei, ua hoʻoikaika ikaika nā kauka i ke kō, akā ʻo ka hopena ma lalo o ke kīpē, ʻo ka hopena o nā hopena a me nā hoʻopiʻi ʻana mai nā lāʻau lapaʻau pinepine pinepine aku i ko lākou kaha, akā inā ʻaʻole ʻoe e ʻimi i ka dosage, mai noʻonoʻo i ka mea kūpono nā lāʻau lapaʻau i ka mea ʻaʻole pono.

ʻO kekahi o kēia mau ʻāpana loiloi o nā moku ka puʻuwai a me ke koko. Ua hōʻike ʻia ʻo ia ka hana maalea loa o ka mālama ʻana i ka maʻi maʻi e hāʻawi i ka hopena kūlike a alakaʻi i ka make vascular. ʻO ka Sugar he hōʻailona wale nō ia o nā maʻi maʻi kaona 2, e kau ana ka maʻi ma ka metabolic syndrome.

ʻO ka lāʻau lapaʻau o ka hanauna hou o Onglisa, i hoʻomohala ʻia e nā kānaka ʻepekema Pelekane a me Italia, ʻaʻole nā antidiabetic wale nō, akā hiki i nā kaha cardioprotective. ʻO nā lāʻau lapaʻau o ka laikini incrlet, e loaʻa iā Onglisa, nā mea hou i loko o ke kahua o ka maʻi maʻi. Hana lākou e hōʻemi i ka momona a me ka hāʻawi kaumaha - ʻo ia kekahi o nā kumu nui no ka hoʻomohala ʻana i ke ʻano maʻi type 2.

Eia kekahi, ʻaʻole ka hoʻonāukiuki o ka infletinomimetics i ka hypoglycemia, kōkua i ka hoʻohaʻahaʻa ʻana i ke koko, a pale i nā ʻoka pancreatic. ʻO ke kumu kūʻai kiʻekiʻe a me ka hemahema o ka ʻike maʻi ma muli o ka manawa pōkole o ka hoʻohana ʻana i nā lāʻau hiki ke hoʻokaʻawale ʻia mai nā hōʻino o Onglisa, akā he mea kēia no kēia manawa.

Ka hoʻonohonoho ʻana a me ke ʻano o ka hoʻokuʻu ʻana

ʻO kēlā me kēia papa Onglisa, ke kiʻi o ia ka mea i hōʻike ʻia ma kēia ʻāpana, aia kahi 2.5 a 5 mg mg o ka saxagliptin hydrochloride i loko o ka ua. Hoʻopili ʻia ka ʻōhua me nā mea hoʻonani: selulose, lactose monohidate, sodium croscarmellose, magnesium stearate a me nā ʻāpana Opadray (ʻūnū, ʻeleʻele a me ka uliuli no ka papa 2.5 mg a me ke keʻokeʻo, ʻulaʻula a me ka uliuli no ka inika o 5 mg).

Hiki ke hoʻomaopopo i ka lāʻau lapaʻau ma ke ʻano (nā biconvex papa me kahi kaila melemele a ʻo ka māka 2,5 / 4214 a pinkish me ka kahakaha 5/4215). Hoʻopili ʻia ka ʻōlelo ma kēlā me kēia ʻaoʻao me ke aniani uliuli.

Oe ke kuai i ka lāʻau lapaʻau lapaʻau. No nā papa Ongliz, ʻaʻole mai ke kumukūʻai mai ke kumukūʻai kumukūʻai: no nā 30 pcs. 5 mg ma Moscow pono ʻoe e uku i 1700 rubles. Ua hoʻoholo ka mea hana i ka noho papa o ka lāʻau lapaʻau i loko o 3 mau makahiki. Paʻi ʻia nā kūlana o ka lāʻau lapaʻau.

Nā hiʻohiʻona Pharmacological

ʻO ka papa hana nui o Onglisa he saxagliptin. I loko o kahi lā ma hope o ka komo ʻana i ke kao ʻōpala, ke kāohi nei i ka hana o ka peptide DPP-4. Ma ka hoʻopili me ka glucose, ʻo ke kaohi o ka enzyme me ka hoʻonaninani (ʻo 2-3 mau manawa) e hoʻonui i ka ʻike ʻana i ka pona o ka ponaide e like me peptide-1 (GLP-1) a me ka glucose-e hilinaʻi i ka insulinotropic polypeptide (HIP).

I ka manawa like, hoʻemi ka nui o ka glucagon i loko o nā b-cell, ka hana o nā naina-b na kuleana no ka hana ʻana o ka insulin endogenous. I ke hopena, ua hoʻemi nui ʻia nā hōʻailona o ka hoʻokē ʻai a me ka glycemia postprandial.

ʻO ke palekana a me ka hana pono o ka lāʻau lapaʻau ua aʻo ʻia i nā hoʻokolohua 6, ma ka hana he 4148 mau mea paahana me nā maʻi like 2. Ua hōʻike nā mea komo a pau i ka dinamika maikaʻi o ka gogemobly glycated, kaona pololi a me ka glycemia ma hope o kahi ukana pākina. ʻO nā lāʻau lapaʻau hou, e like me thiazolidinediones, metformin, glibenclamide, i kuhikuhi ʻia i nā poʻe hui kūʻokoʻa ʻaʻole i loaʻa ka 100% glycemic control.

ʻO nā mea maʻi e lawe ana i nā lāʻau antidiabetic hou i hōʻike i nā hopena like. Ua kūpaʻa ka paona o nā mea a pau i nā hoʻokolohua.

Ma kahi i kauoha ʻia ai ʻo Saxagliptin

ʻO ka maʻi maʻi maʻi me ka maʻi ʻānō o Ongliz i ʻōlelo ʻia:

E like me monotherapy, i hui pūʻia me nā hoʻololi ola.
I ka hui pū ʻana, me ka hoʻohui o ka koho ma mua me ka metformin, inā ʻaʻole hāʻawi ʻo monotherapy i ka mana piha o ka glycemia,
Me nā hua derivatives o ka lālani sulfanylurea a me thiazolidinediones, inā ʻaʻole i lawa nā hui mua.

I nā manawa o Onglisa

No ka mea he ikaika stimulant ka saxagliptin e hoʻonui ana i ka hana o nā b nā a me ke pale aku i ka hana o nā huina b, hiki ke hoʻohana pū me kekahi mau kaupalena, ʻoi, ʻaʻole i hōʻike ʻia ka lāʻau lapaʻau.

Nā makuahine hāpai a me lactating
I ke wā kamaliʻi
ʻO ka maʻi maʻi maʻi me ka maʻi ʻano ʻehā,
Me kahi maʻi diabetes type-2 like ʻole,
Maʻi molaʻi
Inā ʻaʻole ʻae ka mea maʻi i ka galactose,
Me ka hypersensitivity i nā mea kanu o ka pulu.

Ke koho ʻana i kahi hoʻoponopono mālama lapaʻau, ʻaʻole koʻikoʻi ke kauka kauka wale ʻana i nā contraindications i kakau ʻia, akā pū kekahi pū kekahi me kexagliptin o nā lāʻau lapaʻau e lawe nei ka mea maʻi mai nā maʻi concomitant. No laila, ʻo nā lāʻau āpau a pau i ka lolo e hoʻopau pono ai, pono e hoʻomaopopo ʻia ke kauka i ka manawa kūpono.

Nā manaʻo e hoʻohana

Hoʻoholo ke kauka i ka nui o ka lāʻau lapaʻau hoʻokahi, me ka mālama i nā hopena o ka hoʻokolokolo, ka makahiki, ka ʻano o ka maʻi, ka ʻano kū hoʻokahi o ke kino. No Onglisa, nā ʻōlelo aʻo no ka hoʻohana ʻana i ka papa ʻōlelo ma ke ʻano he maʻamau, me ka ʻole o ka hoʻopaʻa ʻia ʻana i ka manawa o ka ʻai. ʻO ka maʻa hoʻomaka hoʻomaka o ka lāʻau no 5 mg / lā.

I ka hoʻomakaʻana o ka papa e mālama ai, ke ʻano ka like me ka regimen maʻamau:

Saksagliptin - 5 mg / lā.,
Metformin - 500 mg / lā.

Ma hope o nā lā 10-15, e loiloi i ka hopena therapeutic o ke regimen i koho ʻia a inā pono, e hoʻoponopono i ka nui o ka metformin, e mālama ana i ke ʻano o Onglisa i loli ʻole.

Inā pau ka manawa lawe i ka lāʻau lapaʻau, ua lawe ʻia ia ma ke ʻano maʻamau ma ka manawa mua. ʻAʻole hiki iā ʻoe ke pālua i ke kapu, no ka mea, pono ke kino i ka manawa e hoʻoiho ai ia mea.

Inā loaʻa kahi moʻaukala o kahi maʻi papalapa, ʻaʻohe pono o ka titration dosis. Me ke ʻano maʻalahi a paʻakikī, hoʻemi ʻia ka maʻamau ma ka manawa 2 - 2.5 mg / lā. (one-one).

I ka wā hemodialysis, inu ka papa ma ka hope o ke kaʻina. ʻO ka hopena o Onglisa i nā poʻe maʻi e pili ana i nā dialy peritoneal i aʻo ʻole ʻia. Ma mua o ka kuhikuhi ʻana i ka lāʻau lapaʻau a ma ke ʻano o ka papa holo, pono ia i ka nānā ʻana i kēlā me kēia manawa i ka hana o nā keiki.

Me nā ala hepatic, kuhikuhi ke lāʻau lapaʻau i ka mahele maʻamau o 5 mg / lā. No nā maʻi maʻi o ka pākeke, ʻaʻole pono ka nui o ka titration, akā pono e noʻonoʻo ʻia ke ʻano o nā keiki.

Hoʻemi ʻia ka nui o ka incretins e ka hapalua me ka mālama paʻakikī me ka inhibitors:

Atazanavir
Ketoconazole,
Igraconazole
Nelfinavir
ʻO Clarithromycin
Ritonavir
Saquinavir,
Indinavir
ʻO Telithromycin.

ʻAʻohe mea ʻike ʻike pili e pili ana i ka hoʻohana ʻana i ka lāʻau lapaʻau no nā wahine hāpai a me nā keiki ma lalo o ke 18 makahiki, no laila ua koho ʻia nā mea analogue no kēia ʻāpana o ka maʻi maʻi.

He hopena hoʻoneʻe a hikiʻole

ʻO nā lāʻau lapaʻau o ka pūʻulu hoʻohui o ka hanauna hou loa kekahi o kahi palekana. Me nā manaʻo āpau a ke kauka, i hoʻomanawanui ʻia ʻo Ongliz e ka hapa nui o nā maʻi maʻi.

I kekahi mau hihia, penei ke kau nei:

Nā maʻi Dyspeptic
Laumapa
ʻO ka pancreatitis
Nā maʻi hōʻeha
ʻO nā maʻi Urogenital o kahi ʻanoʻeha.

Inā hele mai kekahi o kēia mau ʻōuli a i ʻole nā pilikia ʻē aʻe, pono ʻoe e kāpae i ka hoʻohana ʻana i ka lāʻau lapaʻau a nīnau aku i kāu kauka.

No nā kumuʻepekema, ua hāʻawi ʻia ka lāʻau lapaʻau i nā mea hana ma nā hōkeo ma mua o ka 80 mau manawa. ʻAʻole paʻa nā hōʻailona o ka hoʻohālikelike. Hiki ke hoʻopau ʻia ka saxagliptin me ka hoʻohana ʻana i hemodialysis.

Nā ʻōlelo ʻokoʻa

ʻAʻole i kuhikuhi ʻia ʻo Saxagliptin i kahi regiple triple i hui pū ʻia i nā inikini insulin me metformin a me thiazolidinediones, no ka mea, ʻaʻole i aʻo ʻia nā hopena o kēia hōʻaha. Ke mālama ʻia ka mālama ʻana i nā pōpoki i nā manawa āpau o ka mālama me Onglisa, akā me kahi ʻano ʻoluʻolu, ʻaʻole i loli ka dosage, ma nā ʻaoʻao ʻē aʻe.

ʻO Saxagliptin e pili ana i nā hopena hypoglycemic palekana loa, akā i ka hoʻohui me nā lāʻau lapaʻau sulfonylurea hiki ke hoʻonāukiuki i nā kūlana hypoglycemic. No laila, me ka mālama paʻakikī, titration o ka nui o ka hopena ma ke ʻano o ka hōʻemi i ke kauoha.

Ma kahi hoʻohālikelike ʻana i nā lāʻau lapaʻau o ka series incletlet - DPP-4 inhibitors, ʻaʻole i kuhikuhi ʻia ʻo Onglisa, no kekahi mau mea i nā hopena alakaʻi mai nā rashes kaila maʻamau i ka pīhoihoi anaphylactic a me ka angioedema, e koi ana i ka hōʻemi ʻana i ka lāʻau.

No ka mea ka nui o ka lāʻau lapaʻau i ka lactose, ʻaʻole ia i kuhikuhi no ka maʻi maʻi me ka intolerance pakahi, maʻi lactose, hōʻeha glucose-galactose.

I ka wā o ka nānāʻana o nā maʻi maʻi maʻi ma hope o ka mālama ʻana me Onglisa, aia kahi mau o ka hiki ke hoʻomohala ʻana i ka maʻi pancreatitis maʻa. Ke koho ʻana i kahi papa o ka saxagliptin, pono e hoʻomaopopo ʻia ka mea maʻi e pili ana i kahi hōʻailona alohilohi: kū mau a me ka ʻeha nui i ka epigastrium.

Inā pilikia ʻoe i loko o ka ʻōpū, pono ʻoe e ʻae i ka lawe ʻana i ka lāʻau lapaʻau a hōʻike aku i ka malaise i kāu kauka. ʻO nā hopena he pōkole a hoʻihoʻi, kau ma luna o lākou iho ma hope o ka hoʻokuʻu ʻana i ka lāʻau.

I nā hana renal i ke ʻano kūpono a me ka hōʻeha koʻikoʻi, hoʻokahi titration dosis. I nā kūlana koʻikoʻi, hoʻohana ʻia ʻo Onglizu me ka akahele, i ka ʻina papa, hiki ʻole i ka mea maʻi me ka hemodialysis, mai hoʻohana pū kekahi. ʻO ka nānā ʻana i ke kūlana o nā keiki i kēlā mau hihia e lawe ʻia ma mua o ka hoʻomaka ʻana o ka papa o ka mālama ʻana a me kēlā me kēia mahina ʻeono me ka hoʻohana mau ʻana iā Ogliza.

ʻAʻole lawa ka ʻike i ka mālama ʻana i nā maʻi maʻi i ka makahiki ʻelemakule (mai 75 mau makahiki), no laila, lawa kēia ʻano o nā mea maʻi i ka mālama nui.

ʻAʻole i paʻi ʻia nā hopena o ka hopena o Onglisa i ka hiki ke kāohi i ka lawena a i ʻole paha i nā mea ʻenehana. No laila, ʻaʻole e paʻi ka poʻe maʻi maʻi maʻi i ka lāʻau me ka akahele, no ka mea ʻo ka maʻi hilahila ma waena o nā hopena ʻaoʻao. Pono ke nānā pono i ia mau kūlana no ka poʻe maʻi e hoʻohana ana iā Onglisa i ka mālama ʻana i ka paʻakikī, ʻoiai kekahi mau lāʻau antidiabetic e hoʻonāukiuki i ka hypoglycemia.

ʻO ka ʻike no ka hoʻohana ʻana i ka lāʻau lapaʻau no nā pilikia cardiovascular e hōʻike ana i ka lāʻau lapaʻau e hoʻomaʻamaʻa i ka puʻuwai naʻau. I ʻAmelika, ʻoiai me ka palena palena kiʻekiʻe o ke kō, ʻo ke kauka ke kau nei i ka maʻi maʻi me ka arrhythmia Onglizu e hoʻomaikaʻi i nā maʻi glycemic a hoʻihoʻi i ka helu naʻau.

Nā Pili i nā lāʻau lapaʻau me Onglisa a me nā kikowaena

Wahi a ka ʻikepili o ka noiʻi ʻepekema, ʻo nā hopena o ka pilina o Onglisa me nā mea ʻē aʻe i ka wā o ka mālama ʻana, ʻaʻole i maʻi nui.

ʻAʻole ka hopena i ka hopena i ka hopena o ka mālama ʻia no ka hoʻohana ʻana i ka waiʻona, ka mea inu ʻokiʻoni, nā ʻano kanu like ʻole, nā ʻano lāʻau homeopathic.

I loko o ka papa palapala, mai ka pūnāwai hōʻaiʻē me, ʻo Onglisa, ʻO Galvus a me Januvia e hoʻokuʻu ʻia, i loko o kahi peni ʻo - ʻo Baetu lāua ʻo Viktozu.

Nā loiloi a me nā loiloi hoʻohana

Ma nā papa kūkala nui e pili ana i ka lāʻau lapaʻau Ongliza, he mea kupaianaha nā loiloi, aʻo ka drawback wale nō ka mea e pili ana i kāna ʻano Europa.

Minamina, ʻaʻole e hiki ke hoʻōla ʻia nā maʻi, e like me ka wā kahiko, no ka mea, ʻaʻole e hiki ke kūʻai ʻia ke olakino, e like me kāu e ʻike ai, a me ka maʻi maʻamau kīnā 2 ʻaʻole i kapa ʻia ka tikina like ʻole.

Akā ʻaʻole ʻo ka pancreas i kahi maʻi maʻi me ka maʻi type 2 me ka atrophied, he mālama ia no ka hoʻihoʻi ʻana i kāna mau hana, a ua hoʻopau iā ia i mea ʻole ka hana (mai kahi ʻike nui o ka mea huna o ka insulin) o mua.

Ma mua o ka hoʻokuʻu ʻana iā Ongliza i ka mākeke, ua kūʻai aku ka mea hoʻolālā i nā helu he miliona miliona ʻaʻole ia e hōʻike i ka hala ʻana o nā hopena maikaʻi ʻole, akā e hōʻoia pū i kona hōʻoia. Inā kōkua wale nō ka lāʻau lapaʻau i ka hoʻopiʻi ʻana i nā hoʻopiʻi no nā makahiki 10-20, ʻo ia hoʻi no kēia manawa o ka piha ʻana (me ka hōʻeha ʻana o ka naʻau, ka nalina, ka gangrene, ka makapō, ke kaumaha, nā ʻōpū a me ke kuʻi ʻana), ʻoi aku ka maikaʻi o ka mālama ʻana iā ia.

ʻO nā manaʻo e pili ana i ka hiki o Onglisa a me ka hopena o nā lāʻau lapaʻau maʻi i ke olakino o ka endocrinologist Shmul Levit, poʻo. Institute of Diabetology, ʻike wikiō:

Nā hōʻailona no ka hoʻohana ʻana

Ma ka maʻi diabetes type 2, ʻo ka haʻahaʻa o nā pū i ka glucose e hoʻemi nui. Ma kēia hana, aia ke kali i ka hoʻomaka mua o ka synthesis o ka hormone.

I ka wā e hiki mai ana, ua nalo aku ka lua o ka hana ma muli o ka hapa o ka incretins. Hoʻopau ka Onglisa i ka hōʻike o ka DPP 4, ʻoi aku ka lōʻihi o ka incretins i loko o ke koko, ʻoi aku ka nui o ka insulin. Hoʻoholo ʻia ʻo Glycemia ma luna o ka ʻōpū ʻōpū piha a piha hoʻi, hoʻihoʻi ʻia ke hana o ka pancreas. No laila, hoʻolōʻihi ʻo Onglisa i ka hana o kā lākou iho pono'ī, hoʻonui i kā lākou ʻike.

Ke hōʻike ʻia nei ka lāʻau lapaʻau Onglisa me ke ʻano type type 2 (ma ke ʻano ʻai me ke ʻano kūpono a me ka haʻuki) e like me:

hana mua me kekahi mau lāʻau lapaʻau, hui pū me ka metformin,
hoʻohui hou i ka maʻi me metformin, insulin, sulfonylurea derivatives,
monotherapy.

Hoʻonui ka hoʻohana ʻana o Onglises i ka kaohi glycemic.

E hoʻokuʻu i ke ʻano

ʻO ka'āina kahi - USA, akā hiki ke hoʻopili ʻia nā papa i mākaukau ma UK a i Italia paha.

Hana ʻia lākou i ke ʻano o nā papa pōʻai, convex ma nā ʻaoʻao ʻelua, uhi ʻia ka ʻaoʻao waho. Aia nā pā pālani nā helu polū. Kēia ka waihoʻoluʻu o Onglisa ma ka paʻa ʻana o ka waiwai ikaika: 2.5 mg kēlā me kēia ʻāpana ʻalohilohi pale ("2.5" ʻo ia ka mea i kākau ʻia ma kekahi ʻaoʻao, "4214" i kākau ʻia ma kēlā ʻaoʻao), a he 5 mg kēlā me kēia ma muli (helu ʻia "5" a me "4215 ").

Aia nā papa i loko o nā poli i hana ʻia i ka alumini foil: i loko o hoʻokahi pahu 3 polū o 10 mau ʻāpana. Loaʻa kēlā me kēia puʻupuʻu e hoʻokaʻawale iā ia i 10 mau ʻāpana (ma ka helu o nā papa). Pahu ʻia ka pahu pahu pahu mai ka hoʻopili ʻana me nā mea hoʻomālamalama i wehewehe i ke aniani ka pulu.

ʻO ka hoʻohanohano ma ka maʻi maʻi - e inu wale i kēlā me kēia lā.

Oe hiki ke kuai i ka lāʻau lapaʻau no ka maʻi Onglizu i loko o nā lāʻau lapaʻau. Loaʻa nā papa kuhikuhi, akā ʻaʻole nā lāʻau lapaʻau e ukali i kēia rula. I ka 2015, ua hoʻokomo ʻia ka lāʻau lapaʻau i loko o keʻano o nā mea e pono ai, no laila inā kākau inoa kahi maʻi maʻi maʻi, hiki iā ia ke loaʻa me ka manu ʻole.

I ka awelika, ʻo ka uku o ke kīʻaha no nā papa he 30 no ka 1800 mau rubles. E mālama i ka lāʻau lapaʻau i kahi mahana o lalo o 30 mau kiʻekiʻe mai nā keiki. Pono e waiho hou aku ma mua o 3 mau makahiki.

ʻO ka mea hana e hiki ai ke saxagliptin hydrochloride (2.5 a i ʻole 5 mg). ʻO kēia kahi mea hoʻohālikelike o ka inhibitor o kēia wā o DPP-4.

Loaʻa nā mea:

MCC
laktosa lactose,
sodium polio
konekena stearate,
hoʻohuihui hanehana
nā vali.

ʻO ka ʻaoʻao waho o ka papa ʻāpana o ka peʻa OpadryII.

Nā ʻōkuhi no ka hoʻohana

I ka manawa e hoʻomaka ai ka mālama ʻana me Onglisa, pono e loli ka mea maʻi i ka meaʻai kaulike a me ke ʻano hana.ʻO ka lāʻau lapaʻau e hana mālie, no laila, i ka ʻole o nā meaʻai kūpono a me ka hana kino, ʻaʻole ia e hāʻawi i ka uku kūpono no ka glucose. Loaʻa ka lōʻihi loa o ka ʻā o ka mea ikaika ma hope o nā minuke 150, ka hopena o ka lāʻau lapaʻau he 24 mau hola.

Pono e hoʻopau wale ʻia ʻo Ongliz i loko o ke manawa kūʻokoʻa o ka meaʻai. ʻO kahi pākaukau hoʻokahi e like me ke kauoha ʻana he 5 mg.

Inā mālama ʻia ka lāʻau hui no nā maʻi maʻi maʻi, hoʻohana ʻia ʻo Ongliza e hui pū me ka metformin, sulfonylureas a i ʻole thiazolidinediones.

Hāʻawi mākou i kahi haʻawina i ka poʻe heluhelu o kā mākou pūnaewele!

I ka lāʻau mua me ka metformin, hoʻokahi pākahi ma ka pae mua he 500 mg i kēlā me kēia lā. Me kahi hopena hikiʻole, hoʻonui nui ke ʻano.

Inā haʻalele ka mea maʻi i ka hopena hou o ka lāʻau lapaʻau, pono e hoʻomau hou ka hoʻokipa. I kēia hihia, ʻaʻohe mea e pono ke hoʻonui i ka dosis.

E aʻo i nā loea i ka hui pū ʻana me indinavir, ketoconazole a me nā mea ʻē aʻe CYP 3A4 / 5 inhibitors 2.5 mg i kēlā me kēia lā.

Hoʻemi ʻia ka nui o ka dosage i ka 2,5 mg i ka wā e mālama ai me ka antibiotics a me nā hui antiviral.

Nā hiʻohiʻona noi

I ka hoʻomaka mua o nā loli i ka hana o nā keiki, ʻaʻohe pono e hoʻololi i ka dosage. I nā maʻi koʻikoʻi o ka maʻi, hemodialysis, ʻo ke ʻano lāʻau o Ongliza i hōʻike ʻia e 2.5 mg i kēlā me kēia lā. Hoʻomaopopo ʻia ka lāʻau lapaʻau e lawelawe ʻia inā ka pau ʻana o ke kaʻina hoʻomaʻemaʻe koko. Ma mua a i ka wā e mālama ai, pono e nānā i ke ʻano o nā keiki.

ʻO ka hopena o Onglises ma ke kino me ka ʻoihana intracorporal e hoʻomaʻemaʻe ʻole ʻia i ʻike ʻole ʻia.

Me nā loli i ka hana o ka ate, inā hoʻi i ka hōʻeha, ʻaʻole pono ia e hoʻoponopono i hoʻokahi pae.

ʻO ka hopena o ka hoʻohana ʻana iā Onglisa i nā maʻi maʻi ma mua o 65 he like ia me nā mea maʻi maʻi ʻōpio. I ka wā ʻelemakule, pono ʻoe e lawe i ke ʻano maʻamau no kēlā me kēia lā. He mea nui ka hoʻomanaʻo e pili ana i kēia manawa ulu, ʻo ka hana o nā keiki i hōʻemi, ʻo ka hana i loko o kekahi nui i hoʻopili ʻia e lākou.

ʻAʻohe ʻikepili e pili ana i ka hopena kūpono a me ka hopena maikaʻi o Onglisa ma lalo o ka makahiki 18 o kona mau makahiki.

Co-hoʻokele ʻo Onglisa me ka insulin i ka wā mālama ʻaʻole ʻia. ʻAʻohe ʻikepili i ka hopena o ka lāʻau lapaʻau ma ke kaʻa a me nā hana me nā ʻōnaehana mīkini. Lalo paha ka pala ma hope o ka lawe ʻana i ka lāʻau.

ʻAʻole i aʻo ʻia ka hopena o ka waiwai ikaika ma ke kino o ka wahine hāpai a lactating. ʻAʻohe mea ʻike inā hiki i ka mea ikaika ke komo i loko o ka plasenta ma ka pūpū a i loko o ka waiū waiu, no laila ʻaʻole i kuhikuhi ʻia ka lāʻau lapaʻau i kēia manawa. Inā ʻaʻole hiki ke pale aku i ka hoʻohana ʻana iā Onglisa, i ka manawa e lawe ai i ka lāʻau lapaʻau, ua oki ka umauma. I kēia hihia, hiki i ka pilikia kūpono i ke keiki a ʻoi paha ka hopena maikaʻi no ka makuahine i ʻike ʻia.

ʻO nā derivatives o Sulfonylurea e hoʻohaʻahaʻa i ka pae haʻahaʻa glucose. No ka hōʻalo ʻana i kēlā ʻano maʻi me ka launa pū ʻana me Onglisa, pono ia e hōʻemi i ka nui o ka ole o ka sulfonylurea a i ʻole ka insulin.

Me ka moʻolelo o nā hopena koʻikoʻi e pili ana i ka piʻiʻana o ka maʻi o ka maʻi āpau (e komo pū ana i kahi hopena alerine a me ka edema Quincke), ʻaʻole i hoʻohana ʻia ʻo Ongliza i ka wā e hoʻohana ai i nā poʻe ʻē aʻe DPP-4. Pono e hōʻike i nā kumu kumu paha o ka hypersensitivity a fautua i ka hoʻomaʻamaʻa hou aʻe (analog o ka lāʻau Onglisa).

Aia kahi hōʻike pili o ka pancreatitis koʻikoʻi me ka hoʻohana ʻana i ka lāʻau lapaʻau. Pono e ʻike ʻia nā mea maʻi e pili ana i kēlā mau hanana i ka wā e kuhikuhi ai iā Onglisa. Inā aia kekahi mau hōʻike o nā hōʻailona mua o ka pancreatitis, ua kāpae ʻia ka lāʻau lapaʻau.

ʻO ka hui pū ʻana o nā papa, he lactose, no laila, ka poʻe maʻi me ka maʻi a me ka intolerance galactose genetic, ʻaʻole hiki ke lawe iā Onglisa.

Hoʻopili pū me nā lāʻau ʻē aʻe

Hoʻohui hoʻomaʻamaʻa ʻia ke ʻano noʻonoʻo me ka pono o nā loli ola. Inā ʻaʻole lawe ia ia ʻano i ka hopena i manaʻo ʻia, ua hoʻokomo ʻia nā lāʻau lapaʻau hou.

Ua hōʻike ʻia nā haʻawina e hōʻike ana i ka liʻiliʻi liʻiliʻi i ka hui pū ʻana o ka saxagliptin a me nā lāʻau āpau ʻē aʻe.

Hoʻohui me ka hoʻohana ʻana i nā inducers o CYP 3A4 / 5 isoenzymes e kōkua i ka hōʻemi i nā kiko o nā huahana metakola saxagliptin

ʻO ka lawe ʻana i nā derivatives o ka sulfonylurea e hoʻemi nui i ka hoʻokaʻawale o ka glucose i ke koko. I mea e pale aku ai i kēlā me ia ka mea, pono e hoʻemi ʻia ka nui o ka lāʻau Onglisa.

ʻAʻole i hoʻokō ʻia nā haʻawina e pili ana i nā hopena o ke ulaula, nā mea ʻai, a i ʻole ka inu ʻona ma ka saxagliptin.

Nā hana kūpono

ʻO ka Onglisa kahi lāʻau lapaʻau palekana maikaʻi loa, ʻaʻole i ʻike ʻia i nā hopena i kūpono ʻole. Nui nā manaʻo maikaʻi ʻole me ka saxagliptin e like me ka mālama ʻana i ka placebo.

Ke pāpā ʻia ʻole nei ka hoʻohana ʻana iā Onglises i:

maʻi diabetes type 1
ka ʻoihana me ka insulin
lactase hemahema,
maʻi maʻamau ketoacidosis,
hapai
hana waiū
malalo o na makahiki he 18
ka molaki ʻana o kekahi kanaka i kekahi o nā mea o ka lāʻau.

Pono e mālama nui i nā maʻi e hoʻohana:

e hana ana i ka hana a me ka maʻi kaumaha a me ka maʻi pancalitis ma mua.
kanaka kahiko
me ka hoʻohana ʻana me ka sulfonylureas.

I ka wā o ka mālama ʻana me Onglisa, aia ka hopena o nā hopena ʻaoʻao:

maʻi maʻi maʻi urinary
nā maʻi ʻeha hanu kiʻekiʻe
ka mumū o ka mucosa sinus,
ka mumū o ka ʻōpū a me ka puʻu liʻiliʻi,
haki
maʻiʻo pancreatitis
migraines.

Me ka hoʻāʻo ʻia me ka metformin, hōʻike ʻia ka nasopharyngitis iā ia i kekahi mau hihia.

Ua hōʻike ʻia ka hypersensitivity ma 1.5% o nā hihia, ʻaʻole hoʻoweliweli ia i ke ola, ʻaʻole pono ke hoʻokipa.

I ka wā e hui pū ai me ka thiazolidinediones, i hoʻokolokolo ʻia e nā loiloi o Onglise, ua ʻike ʻia ka ulu ʻana o ka edema peripheral palupalu, ʻaʻole pono ia i pau ka hoʻopau ʻana i ka ʻoihana.

ʻO ka pilikia o ka hypoglycemia i ka wā mālama me Ongliza i kūpono me nā hopena me ka pletebo.

Ke keu

Me ka lōʻihi o ka hoʻohana ʻana i ka lāʻau lapaʻau, ʻaʻole i wehewehe ʻia nā hōʻailona o ka makeʻe. I ka hihia o kahi overdose, pono e hoʻomaha ʻia nā hōʻailona. ʻO ka mea hana a me ka huahana metabolic i hoʻopili ʻia e hemodialysis.

ʻAʻohe mau kikowaena ʻOnglises me kahi mea like me ka mea ʻole. ʻO kēia wale nō ka lāʻau lapaʻau me ka saxagliptin. ʻO ka hopena like ma ke kino ke hoʻopuka ʻia e Nesin, Transient, Galvus. Pāpā ʻia ka hoʻohana ʻana i nā ʻōlani Ongliz me ka ʻole o ka ʻae i ke kauka.

ʻO ka lāʻau lapaʻau maʻi Onglis e kōkua i ka mālama koko i lalo o ka kaohi. Hoʻohana kūpono nā papa maʻa. Hiki iaʻu ke hoʻomaopopo i ka maikaʻi ʻaʻole ia i nānā i nā hopena pili. ʻO nā minuses, hiki iaʻu ke inoa i ka overpriced.

Makemake wau i ka lāʻau lapaʻau Onglisa, aia kahi mākaukau maʻa mau no ka hoʻohana ʻana, ua maʻalahi maʻalahi e hoʻohana. I kekahi manawa ua kū mai ke poʻo hōʻeha ʻeha. Kūleʻa wau i ka lāʻau lapaʻau.

ʻO Ongliza lāʻau lapaʻau ka mea kuʻuna o kahi hui hou o ka wai kōkō haʻahaʻa. He ʻano ʻokoʻa ʻē aʻe ia ka mana o ka mana, akā i nā ʻōlelo o ka hoʻokō ua like ia me nā lāʻau lapaʻau kuʻuna, a ma ka palekana ua ʻoi aku ka nui o lākou. He hopena maikaʻi ka lāʻau lapaʻau i nā maʻi concomitant, pale i ka holomua o ka maʻi diabetes a me nā hoʻopiʻi.

ʻO nā mea kūponoʻole ʻaʻole hiki i ka pilikia o ka hypoglycemia, ka hopena i ka paona o ka mea maʻi a me ka hiki ke hoʻohana me nā lāʻau lapaʻau e hoʻokaʻawale aʻe. I ka wā e hiki mai ana, manaʻo nā ʻepekema e hana i nā lāʻau lapaʻau e hoʻihoʻi i ka hana pancreatic no ka manawa lōʻihi.