ʻO nā papa inoa o nā lāʻau maikaʻi loa i ka hui fibrate e hoʻohaʻahaʻa i ka cholesterol koko

He mau maʻi ʻo Atherosclerosis a kokoke i ʻike nā poʻe a pau. ʻAʻole ia he mea kupanaha, no ka mea, ua kapa ʻia kekahi mau ʻepekema i kahi maʻi o ka makahiki 21. Hōʻike ka ʻike o kēia mau mea i kahi hapakolu o nā poʻe kahiko pilikia i ka cholesterol kiʻekiʻe, hiki ke alakaʻi i kahi puka o kahi maʻi e like me ka atherosclerosis. Hoʻākoakoa a haʻahaʻa ke kāpili haʻahaʻa me nā pā o nā kahe o ke koko, hoʻopili i ko lākou lumen a me ka luku ʻana i ka paia. ʻO nā kumu no kēia mea maʻalahi a papaʻi ʻole - nā meaʻai maikaʻi ʻole, ʻano haʻahaʻa haʻahaʻa.

ʻAʻole kū kū ka lāʻau hou i kēia manawa - i ka mākeke lāʻau lapaʻau he nui nā mea kanu i hoʻolālā ʻia e kaua aku ai i ka kolesterol. I kēia lā e kamaʻilio mākou e pili ana i nā fibrates - nā hiʻohiʻona o kēia mau lāʻau, kahi papa inoa o kahi hanauna hou o kēia mau lāʻau a me kā lākou hana o ka hana.

He aha nā fibrates a pehea e hana ai

I nā hoʻonā olakino me ka hoʻonaninani lipid kiʻekiʻe, ʻike pinepine ʻia nā lāʻau o nā pūʻulu nui e pili ana - nā fibrates a me nā statins. Kuhi kēia ʻatikala i ka hui mua.

ʻO nā Fibrates he mau hoʻohui ʻenemi e derivatives waikawa fibroic.

Nā hana hana i ka hana O ka momona ka mea e pale ai i ka hana o nā lipoproteins haʻahaʻa haʻahaʻa a haʻahaʻa loa. Eia kekahi, hoʻonele ka fibrates i ka hoʻopauʻana o ka hōʻeha kino mai ke kino. Ma lalo o ka mana o kēia mau lāʻau.

• i ka maʻi maʻamau o ka moku,
• hoonui ae la ka elasticity o ka pa vascular,
• hoʻemi ʻia nā hōʻailona o ka kolamu nui ma ke koko.

ʻO nā lāʻau momona ka mea nui na pono ma mua o nā lāʻau lapaʻau lipid-haʻahaʻa. ʻO kēia ka mea e hiki ke hoʻomohala i ka piʻi o ka synthesis o nā lipoproteins density kiʻekiʻe (HDL) a me ka hoʻohaʻahaʻa i ka triglycerides. E like me kāu e ʻike ai, ʻo kēia palaka lipid ka "maikaʻi kolala", a hoʻopono maikaʻi ʻia i ka ʻōnaehana vascular. ʻO ko lākou nānā kiʻekiʻe i ke koko e hoʻohaʻahaʻa i ka hiki ke hoʻomohala a me ka holomua o ka atherosclerosis.

Wahi a ka radar, ke ʻano nui o ka hana fibrate i papa. ʻO kā lākou lāʻau ikaika, lipoprotein lipase, i ka wā e komo ai i ke kahe wai, i ka lawe ʻia ʻana i ka ate, ka mea e hoʻowalewale ʻia i kāna hana nui.

ʻAʻole e hoʻomaopopo ʻia: ʻAʻole lapaʻau nā fibrates i ka hopena o nā kaʻina atherosclerotic a ʻaʻole hiki ke hoʻokaʻawale i kahi palakela i hana mua ʻia i ka kolamu ma nā paia vascular. Hōʻalo wale kēia mau lāʻau i kā lākou hōʻola, ulu, a me ka hoʻokumu ʻana o nā foci o ka infiltration a me ka pohō momona. ʻO ia ke kumu he kumu nui a me ka hoʻomaka koke ʻana o ka mālama ʻana i mea nui loa.

Nā hōʻailona no ka hoʻohana ʻana

Nā Pāwila Huila tofia i kohoia ʻO nā kauka me nā lipid metabolism ka maʻi. ʻO ka pahuhopu nui o ka mālama ʻana i ka hoʻohaʻahaʻa ʻana i nā synt synthesis. No laila, e emi iho ka nui o ka LDL i ke koko a hoʻonui ka nui o HDL. ʻO kēia mau ʻōmua ʻelua he mau antagonist, a ʻo ke kolina kiʻekiʻe kiʻekiʻe e pale i ka hopena luku o ka maikaʻi (haʻahaʻa haʻahaʻa).

Eia kekahi, ʻo ka hoʻomākaukau o fibrate i alakaʻi i ka triglycerides maʻamau i ke koko, a ma ka maʻamau, e hoʻoponopono i nā kaʻina o ka momona metabolism i ke kino. ʻO kēlā me kēia lāʻau lapaʻau mai kēia pūʻulu he mau hōʻike pilikino ponoʻī no ke kuhikuhi ʻana.

ʻO nā papa inoa o nā lāʻau maikaʻi loa o ka hanauna hou

ʻO kēia mau lāʻau lapaʻau e ka waiwai ikaika he kumuwaiwai o ka waikawa fibroic. Ua hoʻokaʻawale ʻia lākou ma ʻekolu mau hanauna, e hōʻike ʻia kēlā me kēia ma ka mākeke kūʻai ma lalo o nā inoa kālepa like ʻole.

• Hoʻopau nā hanauna mua
• Hoʻopili i nā hanauna he 2: gemfibrozil, bezafibrat
• ʻO ka hanauna 3 e kau i ka fibrates: fenofibrate, ciprofibrate

Fenofibrate

He lāʻau inu kēia o ka hanauna hope loa. Ma nā papa lāʻau lapaʻau, i kēia manawa hiki ke loaʻa pinepine loa i waena o nā fibrates āpau. ʻAe ia i kēlā kaulana i kāna waiwai antiplatelet - ke pale aku i ka hoʻopulapula o nā ʻano thrombotic a me nā ʻāpana liʻiliʻi o ke koko, e hōʻemi nui ana i nā hōʻika o ke koko. ʻO ka hana nui o ka hana lipid-hoʻohaʻahaʻa, e like me nā fibrates ʻē aʻe, e pili ana i ka hapa pōʻino o ka cholesterol a me ka LDL, hoʻemi ʻana i kona synthesis i loko o ka ate a, i ka manawa like, kōkua i ka hoʻonui ʻana i ke kūpaʻa o HDL - "pono" kolesterol.

Inā mākou e hoʻohālikelike i ka fenofibrate me nā lāʻau o nā hanauna ʻē aʻe, a laila loaʻa iā ia kahi kikoʻī liʻiliʻi loa o nā hopena o ka ʻaoʻao. ʻO ka bioavailability kiʻekiʻe a me nā maʻalahi maʻalahi. ʻO ka maʻa loa loa i kēlā me kēia lā he 200 mg. Pono e lawe i ka lāʻau lapaʻau i ka wā e ʻai ana. Me kēia ala, ʻo ka hoʻopuhipiha piha ʻana o ka lāʻau.

I loko o nā lāʻau lapaʻau, nā mea hoʻohālikelike me ia me ka mea hana ikaika like ʻia i hōʻike ʻia, ma lalo o nā inoa ʻo Lipantil, Tricor, Nolipax, Lipofen, Fenofibrat Canon.

Bezafibrat

Hoʻomaka ia ma nā papa me kahi kao o 200 milligrams. ʻAʻole i like fenofibrate, ua lawe ʻia ma mua o nā papa ʻaina. ʻO hoʻokahi papa ke ʻano o ka mālama ʻana i hoʻokahi malama, a laila ua hana ʻia kahi hoʻomaha no ka lōʻihi like. Hōʻike ʻia kēia lāʻau lapaʻau o ka pūʻulu fibrate e ka bioavailability kiʻekiʻe a me ka wikiwiki wikiwiki mai ke kino.

Ma nā lāʻau lapaʻau e hiki ke loaʻa paha ma lalo o nā inoa inoa inoa ʻo Besifal, Tsedur, Oralipin.

Choline Fenofibrate

ʻO ia kahi prodrug e kūlike i ka kōpili i hoʻohuli ʻia i loko o ka acid fenofibroic. Ua kuhikuhi ʻia no nā mea maʻi me nā ʻano III, IV, a me V hypercholesterolemia (e like me ka helu ʻana o Fredrickson). ʻO ka inapanui nui loa o nā lā he 135 mg. ʻO ka hoʻohuiʻole me ka waiʻona.

Hiki ke loaʻa ma ka inoa kālepa kālepa Trilipix.

He lāʻau lapaʻau kēia no ka hanauna 1st o nā fibrates. I kēia manawa, ʻaʻohe lilo ia ma muli o nā hopena hopena pinepine loa. Hiki i kona hoʻohana ke alakaʻi i ka cholestasis kidney, ke kūkulu ʻana i nā pōhaku i ka ʻōnaehana hepatobiliary a me ka exacerbation o cholelithiasis.

Eia nō hoʻi ma ke ʻano o kona wā i koho ʻia ai, ʻeha ka wahī. Hōʻike ʻia kēia e nā ʻōnaehana neuromuscular, myositis a me myalgia. Hiki i nā mea maʻi ke hoʻopiʻi i ka hemahema o ka hope, nāwaliwali, a me nā hōʻailona o ka hoʻomālamalama. I ka wā ma mua (ʻoi aku ma ka hopena o ka kenekulia 20), ua kuhikuhi ʻia i nā mea maʻi me nā loilo atherosclerotic o ka lāʻau coronary, peripheral, a me nā moku serebral.

Nā inoa kūʻai no kēia ʻano o ka lāʻau lapaʻau: Lipomid, Amotil, Lipavlon, Miskelon

ʻĀpopopibrate

He nui nā kūʻokoʻa o kēia lāʻau lapaʻau i kāna kūlako lāʻau lapaʻau - e hoʻololi ana i ke ʻano o ke ʻano o ka cholesterol. Hoʻomaʻamaʻa kēia ma muli o ka hikiʻole o ka hana o ka hoʻohuihui o ka mevalonic acid i loko o ka ate (meval acid acid he mea hoʻomalu i loko o ka chain formation kolala). A ʻo kahi hopena, ʻoi loa ka kolamu, nā haʻahaʻa haʻahaʻa haʻahaʻa a me ka triglycerides i ʻike pinepine ʻia i nā helu. A ke hoʻonui nei ka HDL, e hoʻonui aʻe. Hoʻohana ia no ka pili a me ka pili o ka endogenous hypercholesterolemia, a me kēlā mau kūlana kahi i hiki ʻole ai i nā lāʻau lapaʻau ke hoʻopō. ʻO Lipanor ka inoa kālepa.

Nā ʻōkuhi no ka hoʻohana

E like me nā mea liʻiliʻi e hoʻemi ana i nā lipid, pono ke lawe ʻia nā fibrates ma hope o ka nīnau ʻana i kahi loea. Aia nā hiʻohiʻona i nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana ma muli o ke ʻano o ka lāʻau lapaʻau a me kona hanauna. Lawe ʻia nā lāʻau lapaʻau ʻekolu me nā meaʻai, ka hoʻomaha ma mua o ka papaʻaina. ʻO ka pinepine o ka hoʻokomoʻana mai ka manawa a i ʻekolu mau manawa i ka lā.

E noʻonoʻo i nā contraindications a me nā hopena hopena o kēia papa papa kolamu maikaʻi.

Nā hopena ʻaoʻao a me nā contraindications

ʻO nā Fibrates ka lāʻau lapaʻau e hoʻopilikia nui i ke kino. No laila, ua koho ʻia lākou e kekahi kauka loea ma hope o kahi hoʻopaʻa ʻana. Ma mua o ke koho ʻia, pono e hoʻomanaʻo i ka nui o nā contraindications no kēia hui, ʻo ia hoʻi:

• ʻAʻole hoʻohanaʻia nā Fibrates i ka hana maʻi pediatric. Ua hoʻohālikelike lākou no nā keiki.
• I ka wā hāpai a me ka lactation, ʻaʻole i kuhikuhi ʻia kēia mau lāʻau, no ka mea he hopena teratogenic a hiki ke komo i loko o ka waiū umauma.
• ʻO ka maʻi hypersensitivity i ka lāʻau a i ʻole nā ​​mea i hoʻohui ʻia.
• ʻO nā mea maʻi me ka maʻi puʻuwai concomitant a i ʻole nā ​​maʻi lōlū, i ka nui me ka hiki ʻole o ka renal.
• Hoʻomaopopo i ka poʻe maʻi alakaʻi
• ʻO ka maʻi me ka mōʻaukala o ka pancreatitis aʻeha paha.

ʻAʻole noho ka fibrates maoli, aia nā huahana āpau. No laila, e like me kēlā me kēia mea synthetic, loaʻa nā fibrates i kekahi mau hopena ʻaoʻao. Eia nō naʻe, inā no kā lākou hanauna mua, ʻo ia ka papa inoa o ka ʻaoʻao i nā ʻaoʻao o ke kuhikuhi, a laila no ka hanauna hope loa, he nui loa ia e hoʻēmi ana i ka lua a me ka maʻamau. Me nā lāʻau lapaʻau o kēia ʻōpio, ʻo Fenofibrate ka mea maʻamau i kuhikuhi ʻia e nā kauka. Ke hoʻohana nei i kāna hoʻohālike, ʻike mākou i nā hopena pili i kēia hanauna.

Ua helu ʻia ka helu helu helu ma nā hopena o ka lawe Fenofibrate. Ma kēia noiʻi ua pili ʻia nā maʻi 4389. I waena o lākou, ʻaʻole i manaʻo i ka mea maʻi i ka hopena maikaʻi o ka lāʻau. 8.9% o nā mea pane i nānā i nā ʻōpū o ka ʻōpū o ka ʻōpū. 1.1% - ua loaʻa ka nāwaliwali o ka naʻau a me nā poʻo hōʻeha. A me nā mea aʻe o nā hopena ākea maʻamau, hōʻike nā kuhikuhi i nā fibrates i kahi helu o nā hoʻopiʻi pinepine ʻole - he hōʻemi i ka hemoglobin i loko o ke kahawai a me kahi hamo ma ka ʻili.

ʻO nā ʻokoʻa ma waena o nā fibrates a me nā statins

ʻO nā Fibrates a me nā statins ʻelua mau ʻāpana like o nā lāʻau lapaʻau, me nā ʻano hana like ʻole a me nā mea hōʻike ʻē aʻe. No laila, nīnau i ka nīnau - ʻoi aku ka maikaʻi, fibrates a i ʻole statins - hiki ʻole. ʻO ka ʻokoʻa nui ma waena o nā fibrates ka mea hiki ke hana ma triglycerides. Pau kēia o ke ʻano o nā lāʻau lapaʻau e hōʻike i kēia waiwai.

ʻO nā statins nā lāʻau lapaʻau e kuhikuhi ana i ke hoʻohaʻahaʻa ʻana i ka cholesterol "ʻano maikaʻi" a hoʻonui i ke kiʻekiʻe o ka "maikaʻi". ʻIke ʻia he hana nā fibrates. Akā ʻaʻole, hana i nā statins i nā ʻoka a me nā pale ʻana i nā ʻōnaehana o ka enzymatic e hōʻiliʻili ai i ka synt synthesis. A e hoʻokaʻawale i - hoʻoulu ʻia i ka hoʻopau ʻana o nā cholesterol maikaʻi mai ke koko a hoʻēmi i ka paʻa ʻana o nā triglycerides.

Inola e noiʻi e nā ʻepekema London Hōʻike i nā statins i hoʻopili maoli i ka puʻuwai iho, ke kaupaona nei i kona ʻano a me nā hana. Ma lalo o kā lākou hana, ua hoʻemi nui ʻia ka nui o nā hihia o ka hypertrophy cardiac. Mai poina e pili ana i ko lākou hopena ma nā kīʻaha koko - ke piʻi nei ko lākou elasticity, hoʻoikaika i ka paia vascular, a me ka manawa o ka low-density cholesterol e noho ana ma luna o ia ke emi nui.

E like me nā helu a me nā hana lapaʻau, ʻoi aku ka nui o nā hopena therapeutic o nā statins ma hope o ka hōʻemi o ka cholesterol i kahi māka o ʻoi aku ka 7,4 mmol i pāhau. Inā hoʻonui ʻia kēia paepae i ka ʻōlelo lipid, a laila ma nā mea āpau, pono ke hoʻonohonoho ke kauka i ka lāʻau paʻakikī i kekahi mau lāʻau lapaʻau. ʻO ka maʻamau, kuhikuhi nā hui kuʻu me nā fibrates.

Nā manaʻo kauka

E ʻōlelo ʻoluʻolu nā kauka lapaʻau e pili ana i nā fibrates. ʻAʻole makehewa, no ka mea ua kū pinepine kēia mau lāʻau i kā lākou koho. Hōʻike lākou i ka cholesterol koko, he mea koʻikoʻi loa. Wahi a nā noiʻi, i ka wā e hoʻohana ana i nā lāʻau lapaʻau mai ka papa inoa o nā fibrates, e like me ka fenofibrate a i gemfibrozil paha, he hōʻemi nā mea maʻi i ka maʻi naʻau coronary, ka kūlana maʻamau o nā kīʻaha o ka lolo a me ka puʻuwai, a ua hōʻemi ʻia ka hopena hōʻeha o ka naʻau a me nā hōʻeha.

No laila, ʻo nā fibrates ka lāʻau i hakakā i ka cholesterol kiʻekiʻe. Ua hoʻohālikelike ʻia lākou e nā loea no kekahi mau ʻike a kūʻai ʻia aku i nā lāʻau lapaʻau ma o ka lāʻau lapaʻau wale nō. ʻO nā kumumana o ka waikawa fibroic he hapa o ka mālama paʻakikī o ka atherosclerosis. Eia kekahi, ʻo ia nā lāʻau nui a me nā mea nui e hakakā ai i ka hakakā me nā triglycerides i hoʻonui ʻia i ke koko o nā mea maʻi.

Gemfibrozil

ʻO kaʻenehu Hypolipidemic o ka hui o nā fibrates o ka hanauna II. Loaʻa ʻia e ka ʻimi no ka loaʻa ʻana o nā mea hikiʻole ke hoʻopukapuka ʻia o ka clofibrate. A ʻo kahi hopena, loaʻa i nā mea ʻohiʻemi haʻahaʻa loa a loaʻa ʻole kahi laikini haʻahaʻa e hōʻemi i ka hana ʻana a me ka hoʻokalakupua o nā lipids atherogenic. Loaʻa ma ke ʻano o nā kapsul o 0.3 g a i ʻole nā ​​papa o 0.45 g o ka mea ikaika.

Ma ke kānāwai, ke hoʻomaka nei ka nui o nā lāʻau lapaʻau mai 2 mau papa i kēlā me kēia lā. Lawe ʻia ka hoʻokau ʻia 30-40 mau minuke ma mua o ka ʻai ʻana, no ka nui o ka loaʻa ʻana aku o ka maka. Loaʻa ka hopena therapeutic ma hope o 1-2 mau pule o ka hoʻokomo maʻamau. Loaʻa ka hopena kiʻekiʻe ma hope o nā hebedoma 4, ma hope o ka hoʻomau ʻia ʻana o ka dynamics maikaʻi. I waena o nā hopena hopena hiki ke lawe ʻia i:

• ninini
• āhāhuʻe
• luhi, luhi
• hiamoe
• nā hopena kūlohelohe
• ka wā pōʻino o ka nānā ʻana.

Hoʻopilikia ka lāʻau lapaʻau i ka wā hāpai a me ka lactation, i nā keiki ma lalo o 18 mau makahiki o ka makahiki, i mua o nā maʻi o ke aʻa a me nā puʻuwai. ʻO ka kumukūʻai kumukūʻai ma nā māka lā Lūkini he 1,500 rubles i pā pākau he 30 mau papa.

Nā hopena hopena o nā lāʻau lapaʻau hou

ʻOiai ke neʻe nei ka lāʻau lapaʻau i ka hoʻopau ʻana i nā hopena hopena mai ka lawe ʻana i nā lāʻau lapaʻau, a hiki i kēia lā, ʻo Fenofebrat he ʻelele o ke kolu o ka hanauna o ka hui fibrate, aia nō kekahi mau hopena ʻaoʻao, e ʻike ʻia ana ma kahi o 10% o nā maʻi. ʻO kekahi o nā hopena hopena maʻamau ʻole i loko o ka ʻōpū, ka ʻeha ʻana i loko o loko, a me ka huhū ʻana.

ʻO nā helu o nā hopena ʻaoʻao ma hope o ka lawe ʻana i ka hanauna o III fibrates.

Ma kahi o 1 mai o nā mea maʻi 100 e loaʻa i nā hopena ʻaoʻao e like me:

• nāwaliwali ʻōiwi
• lie kanikela
• ninini
• hoʻemi i ka hemoglobin i loko o ke koko,
• ʻūlū keʻokeʻo polū ʻōpala.

Loaʻa pinepine i ka hana lapaʻau i loaʻa nā hihia o ka hina o ka lauoho, ka hoʻomohala ʻana o ka hepatitis. I kēia hihia, ua hoʻopau koke ka lāʻau.

Hoʻopau i nā statins - a ʻoi aku ka maikaʻi?

ʻO nā statins he lipid-hoʻemi haʻahaʻa i hoʻolālā ʻia e hoʻoliʻiliʻi i ka metabolid lipid a i ʻole, maʻalahi, e hōʻemi i ke kiʻekiʻe o "cholesterol maikaʻi" a hoʻonui i ke kiʻekiʻe o ka "cholesterol maikaʻi". ʻOiai kekahi hopena like, ʻokoʻa ka loiloi o nā hana a nā statins i nā fibrates.

E hana ana nā statins i nā pehu o nā ate, ka ālai ʻana i nā huina e pili ana i ke kāpili ʻana o ka kolamu, ma muli o kahi e hoʻemi nui ʻia kona pae ʻana. Hoʻonui hou nā statins i nā kīʻaha koko, hana iā lākou i kahi elastic, e hōʻemi i ka mea e hoʻonaninani ana i nā hopena lipid lipher ma nā paia.

Ua hōʻike ʻia nā haʻawina ma nā kulanui ma Lākana e ʻoi aʻe i nā hopena a pau i hōʻike ʻia ma luna nei, e hoʻomaikaʻi ai nā statins i ke ʻano a me ka hana o ka puʻuwai. ʻO ka poʻe e lawe maʻamau i kēia pūʻulu o nā lāʻau lapaʻau e hōʻemi i ka nui o ka puʻuwai naʻau puʻuwai, ʻo ia kahi hōʻailona o ka nāwaliwali o ka ʻiʻo. I kēia manawa, e hoʻemi i ka cholesterol, nā statins o ka hanauna 3 a me ka 4 i hoʻohana ʻia: Atorvastatin a me Rosuvastatin.

ʻO ka ʻokoʻa nui ma waena o nā fibrates a me nā statins i ka hopena o ka mea i ka mua ma ke kiʻekiʻe o ka triglycerides. ʻO ka hoʻohana ʻana o nā statins, a me nā lāʻau lapaʻau ʻē aʻe i kēia manawa, ʻaʻole hiki ke pale loa i ka hoʻomohala ʻana i ka atherosclerosis a me kona mau hopena, a hele mai kekahi manawa ʻike ʻia nā hiki o nā statins, a me nā loli hou aʻe i nā pona a me nā mea ikaika e hana aku ai i nā hopena ʻoi aku ka maikaʻi.

Wahi a ke ʻano lapaʻau, hoʻopau ʻia nā hiki o nā statins i ka pae kolamu ma ka pae o 7.4 mmol / l a i ʻole. Ma nā hōʻailona ma luna o kēia paepae, nā kauka me ka huki ʻole i ka hoʻopili ʻana i kekahi mau lāʻau lapaʻau, maʻamau e hoʻohana ʻia nā statins i hui pū me nā fibrates.No laila, e ʻōlelo ʻoi i nā mea a nā lāʻau lapaʻau ke ʻoi aku paha.

ʻIkepili hana hana

ʻO ka mea hana hana i ka lāʻau lapaʻau Hexal. ʻO kēia kekahi o nā māhele i Novartis Corporation, kahi i kaona lua i ka honua ma ke ʻano o ka nui o nā lāʻau lapaʻau i hana ʻia. Papahana - Novartis ma Switzerland.

Nā kuʻuna no ka mālama ʻana i nā maʻi me ka hyperlipidemia

ʻO ka pahuhopu nui o ka maʻi no nā maʻi me ka hyperlipidemia e hoʻokō i nā waiwai maikaʻi loa o ka cholesterol kiʻekiʻe, haʻahaʻa a me ka kiʻekiʻe lipoprotein kūloko kiʻekiʻe, triglycerides. ʻO ka hana a ke kauka ke nānā aku i ke kūlana o ka mea maʻi a me ka hiki ke hoʻonāukiuki mai ka ʻōnaehana cardiovascular.

ʻO ka loli haʻahaʻa a me ka haʻahaʻa, ua hōʻike ʻia kahi loli hoʻololi i ke ola a me ka meaʻai. Hāpai ʻia:

• Ke kaupalena ana i ka ʻai ʻana o nā momona momona, ka helu helu ʻana mākia kūpono, ka mālama ʻana i nā loina o ka meaʻai kūpono (i kekahi manawa ua lawa wale nō ia e hoʻoponopono i ke kiʻekiʻe o ka kolamu a me nā lipher atherogenic)
• pāʻani pā pāʻani: me ka momona, pono ʻoe e hoʻomaka me nā lelo liʻiliʻi e pale aku i nā pōʻino i nā ʻōpū, ʻōnaehana cardiovascular, etc.
• hāʻawi i nā hana maikaʻi.

Ma muli o nā hana lapaʻau ʻole i ka USA, Finland a ʻo Ausetalia ma mua o 40 mau makahiki, ua hōʻemi ʻia ka make mai ka maʻi naʻau coronary e 50%.

Eia naʻe, aneane hiki ʻole ke hoʻowalewale i kekahi mau mea pili i ka maʻi (nā pili e pili ana i ka makahiki, nā predisposition hoʻoilina). Ma ka loaʻa ʻole o kahi hopena mai nā lāʻau lapaʻau, ʻaʻole mālama ʻia kekahi mau lāʻau lapaʻau. Pili:

• statins
• sequestrants o nā hua bile,
• hoʻōla nicotinic
• nā huaʻai.

Inā ʻaʻole lawe mai ka monotherapy i ka hopena i makemake ʻia, e aʻo ʻia e lawe i kekahi mau lāʻau i ka manawa like.

Lapaʻau lāʻau

ʻO ka paʻakikī o ka hana a Bezafibrat he mea paʻakikī:

• Hoʻonui i ka hoʻōla ʻana a me ka catabolism o nā lipoproteins haʻahaʻa haʻahaʻa ma muli o ka hoʻihoʻi ʻana o kahi molito lipoprotein enanthate kūikawā,
• e hoʻolohi i ka hana o ka caretyylase o ka enzyme, pono no ka hoʻouka ʻana o nā hua bile,
• hoʻonui i ka hoʻonuiʻana i ka cholesterol me ka hua bile.

Ma lalo o ka hopena o ka lāʻau, hōʻemi ka pae o ka triglycerides i ka 50%, nā kiko o ka kolamu a me ka LDL cholesterol - a hiki i 25%. Ua nānā nā kauka i ka piʻi ʻana o nā lipoproteins kiʻekiʻe.

Eia kekahi, ʻo Bezafibrat:

• hōʻemi i ka hoʻohuihui ʻana o ka uric acid,
• hōʻemi i ka hana o C-reactive protein,
• hōʻemi i nā pae fibrinogen.

Hoʻonui ʻia ka hana Anticoagulant a me nā hana fibrinolytic e ka hoʻemi ʻana i ka kahe o ka fibrinogen a me ka hiki ʻana i ka platelet aggregation. No laila, ʻo ka hoʻohana ʻana o Bezafibrat he mea pale i ka pale o ka thrombosis a me nā hōʻeha puʻuwai a me nā kaha.

Hōʻike e pili ana i ka ʻike ikaika

I nā makahiki i hala iho nei, ua aʻo ʻia ka papa hana o ka bezafibrate i nā kikoʻī hou aku. Hana ka hana i ka pae liʻiliʻi, hoʻāla i nā ʻĀina ʻĀpana pae (PPAR-α). Pēlā, e lawe ʻia aku ka hoʻoponopono ʻana o ke kāpili ʻana o nā apoproteins a me ka make o ka hoʻoneʻe ʻana i nā momona momona. He hopena maikaʻi ka hāmeʻa i nā ʻāpana like o nā lipid a me ka lipoprotein metabolism.

I ka huina holoʻokoʻa, ua hōʻike ʻia kekahi mau isoforms o nā mea hoʻokele o ka PPAR - α, β / δ a me γ. Loaʻa ʻia lākou ma nā ʻano ʻāpana a ua loaʻa kēlā me kēia ʻano kekahi, nā hana pilikino kekahi. Hoʻokomo ʻia ʻo PPAR-α i ka nui o nā ʻōpū, nā ʻuna, ka kiko adipose, nā ʻōpū a me ka puʻuwai. ʻO kāna hana e hoʻoulu ai i ka ulu o nā protein e pili ana i ka ʻokiʻoki ʻana o ka lipids a me β-oxidation o nā momona momona.

ʻO ka maʻamau, mālama ʻo PPAR ma ka pae genetic i kahi kaulike ma waena o ka hoʻomoʻo o ka momona o nā momona momona i nā hepatocytes (ʻĀnō a me nā ʻĀpana pae "kuleana" no kēia hana) a me kā lākou hōʻiliʻili ʻana i nā adipocytes (ma muli o ka hana o PPAR-γ). ʻO kēia ka hoʻokele ma waena o ka mālama ʻana a me ka hoʻolilo ʻana i ka ikaika ma ke kino o ke kanaka.

Ua ʻike nā ʻepekema ʻepekema ʻo PPAR-α i kahi hana koʻikoʻi i ka hoʻomohala ʻana o ka hyperlipidemia a me nā pilikia ʻē aʻe o ka momona metabolism. A, no laila, ʻo ka hopena o ka bezafibrat ma luna o kēia mea hoʻopiʻi, e alakaʻi pū ʻia ana i ka normalization o nā kiʻi ʻāpana lipid. Akā, ua hana like kahi hana like o ka lāʻau lapaʻau ma hope o kona hoʻokomo ʻana i ka hana lapaʻau.

Nā hōʻailona no ka lawe ʻana i ka lāʻau lapaʻau

Ua koho ʻia ʻo Bezafibrat no kekahi mau ʻano o ka hyperlipidemia (pinepine ʻo III, IV, V, akā ma ka ʻano o ke kauka, hiki ke hoʻohana ʻia no nā ʻano maʻi ʻē aʻe). ʻO ka maʻamau, ke kuhikuhi ʻia nei ka lāʻau i ka lilo ʻole o kahi hopena mai kaʻai a me ka hoʻōha kino a i ʻole i nā mea maʻi mai ka pūʻulu kiʻekiʻe o ka nui o ka maʻi cardiovascular.

Wāwī palapala noi

I ka pilina me nā mea ulu o pharmacokinetics, ka papa inoa o nā contraindications no ka lawe ʻana iā Besafibrate e pili ana:

• nā maʻi koʻikoʻi o ka pūpū, ka pā ʻana i ke aniani a me ka pahu o ka biliary (ʻo kahi ʻokoʻa o kēia kānāwai he hōʻea ʻo ka momona o ka ate),
• haʻi ʻia nā kālaipili o nā keiki,
• na keiki a me na opio malalo o na makahiki he 18
• ka molaki ʻana o kēlā me kēia ʻāpana.

Eia kekahi, ua pau ka hoʻohanaʻana i ka lāʻau i ka wā o ka wā hāpai. Eia kekahi, i ka wā o ke aʻo ʻana, pono e haʻalele ka umauma.

Nā hiʻohiʻona o ka noi a me nā dosage

Koho ʻia ka ʻīpī no kēlā me kēia maʻi. I kekahi mau hihia, hōʻike ʻia ke ʻano hui. Maikaʻi ʻoi aku ka maikaʻi o ka hui pū ʻana o Bezafibrate me nā lāʻau lapaʻau mai ka pūʻulu statin i nā maʻi me nā maʻi triglycerides kiʻekiʻe. Hoʻonui nui kēia hōʻiliʻili i ka hopena o ka hoʻomohalaʻana i nā hoʻopiʻi cardiovascular i nā maʻi me nā maʻi maʻi a me ka momona.

Hiki paha nā hopena hoʻohālikelike

ʻAʻole e like me nā fibrates o ka mua-mua, ke kūleʻa maikaʻi nei ka lāʻau. Hōʻalo ʻia nā papa ʻaina ʻole e nā hopena ʻaoʻao.

Eia naʻe, wehewehe nā ʻōlelo kuhikuhi i kēia ka hopena pili o ka lapaʻau.

• nausea, emi iki pinepine -
• ʻeha ka ʻōpū
• nā maʻi ʻino
• he ʻano hūnā
• ʻāʻā naʻau
• ka hoemi i ka hana moekolohe,
• alopecia.

Eia kekahi, hiki i ka hoʻohana ʻana o Bezafibrat ke hoʻololi i nā kānana o ka hoʻokolohua hoʻoliʻiliʻi a biochemical a me ka maʻamau (hōʻemi i ka hemoglobin, nā keʻena koko keʻokeʻo, e hoʻonui i nā enzymes o nā palu, a pēlā aku).

Hoʻopili pū me nā lāʻau ʻē aʻe

Pono e mālama ʻia i ka wā mālama me ka lāʻau lapaʻau e hiki mai ana.

• Anticoagulants (Coumarin, etc.), a me nā mea hoʻohana anti-inflammatory non-steroidal - nā huaʻai o salicylates, butadiene. Hoʻoulu ʻo Bezafibrat i kā lākou hana, ka mea e hoʻonui ai i ka hoʻōla o ka hoʻoliʻohao.
• Nā ʻāpana. ^ E Ha yM. Kūkulu ʻia kahi koho dosage pilikino ma muli o ka hiki ʻana o ka rhabdomyolysis (maʻi ʻino, i hui pū ʻia me ka luku hou ʻole ʻana o nā pona fiber mus).
• Antidiabetic (hypoglycemic) lāʻau lapaʻau. Hoʻololi ʻo Bezafibrat i ka hoʻololi ʻana i nā kiko i loko o ka glucose, pono ia e hoʻoponopono nui ʻia.
• Immunosuppressants. ^ E Ha yM. Hoʻonui ka ʻokoʻa o nā ʻōpiopio kōpoki.

No laila, he mea pono e hoʻomaopopo i ke kauka ma mua e pili ana i nā lāʻau lapaʻau i lawe ʻia a i ka wā e hiki mai nei, e hoʻonohonoho i ka hiki ʻana o ka lapaʻau paʻakikī.

Nā ʻōlelo kikoʻī

Me ka makaʻala, ua hoʻokaʻawale ʻia nā papa ʻo Bezafibrate no nā poʻe maʻi me ka nui o ka waika o ka ʻōpū o ka gastric a me kahi predisposition e wehe i nā ʻeha a me ka ulcerative o ka papa kūloko. Eia nō hoʻi, ma ka papa holoʻokoʻa o ka mālamaʻana, e pono ka mālama o ka ʻōlelo lipid a me nā ʻōnaehana koko lapaʻau. Eia kekahi, ua hāʻawi ʻia ka hoʻokolohua ultrasound maʻamau o nā ʻōpū o ka ʻōpū.

ʻO ka lā kau

ʻO 3 mau makahiki mai ka lā o ka hoʻopuka.

Hoʻolaha ʻia ka hōʻemi ʻana i ka hana e like me ka alakaʻi ʻana e ke kauka ma hope o ka maʻamau o ka pauku lipid.

I kēia manawa, loaʻa wale ke Bezafibrat ma ʻEulopa.

I ko mākou ʻāina, hiki i nā kauka ke hāʻawi i nā lāʻau lapaʻau mai nā hui fibrate.

Eia nō naʻe, ʻōlelo aku nā kauka iā Bezafibrat no ka mea i hōʻoia ʻia i ka hopena lapaʻau a me ka ʻike palekana kiʻekiʻe.

ʻO ke kumukūʻai o ka lāʻau lapaʻau a pehea e kūʻai ai

ʻAʻole kākau inoa ʻo Bezafibrat ma ka ʻāina o ka Rusia Russian, akā ma Europa ʻaʻole hiki ke kūʻai ʻia i nā wahi āpau. Aia kekahi lāʻau lapaʻau i kūʻai wale ʻia ma Kelemānia, kahi mai kahi o nā hui waena e hāʻawi ana i ka hāʻawi ʻana.

Ma lalo o ke kauoha e hiki ke lawe ʻia i Moscow, St. Petersburg a me nā kūlanakauhale ʻē aʻe o Rusia. ʻO ke kumukūʻai o ka lāʻau lapaʻau e hilinaʻi ana i ka nui o ka waihona o ka mea ikaika a ma kahi o 70 euros no ka pā o 0.2 g a me 80 Euro - 0.4 g Ma kahi pā - 100 mau papa.

Hōʻike nā kauka i nā kauka

ʻO Tatyana Stepanovna Vinnitskaya, cardiologist: "ʻO ka Hyperlipidemia ke poʻo o ke kanaka hou. ʻO ke ola maʻalahi, ka hana ʻino, ka palaka ʻole e alakaʻi pinepine i kekahi pilikia e like me ka predisposition genetic a me nā mea ʻē aʻe. Pili pinepine ke kauka i ka manawa o ka hopena o nā maʻi e pili nui ana i ka maikaʻi o ka mea maʻi. I waena o nā lāʻau lapaʻau hypolipidemic, ua hoʻohālikelike ʻia ʻo Bezafibrate he lāʻau lapaʻau maikaʻi loa me ka liʻiliʻi o nā hopena hoʻohalike. "

Nā Hōʻike Hoʻomaʻi

Julia, 34 makahiki: "He ola maʻa a me ka maʻamau o ka" hopu ʻana "i kahi ʻano ʻino e alakaʻi i kahi hopena kūpono ʻole - obesity me nā hopena hope loa i ke ʻano o ka pōkole o ka hanu, arrhythmia, a lele i ke koko. Hele wau i ke kauka, a ma waena o kekahi mau mau ho'āʻo ʻē aʻe i kau ʻia ka ʻike lipid. Ua manaʻo ʻia nā hopena. Ua ʻōlelo ʻia ʻo Bezafibrat iaʻu. Ua lawe lōʻihi wau i ka lāʻau lapaʻau no ka manawa lōʻihi, ʻike wau i ka hopena koke, ʻaʻohe ʻano ʻōpiopio. ”

Pehea e wehe ai i kahi mea hoʻopunipuni

I nā wahi mākia Lūkini ʻaʻole hiki ke hoʻokokoke kumu mua, no ka mea ʻaʻole i kūʻai maʻamau ʻia ka lāʻau lapaʻau ma ka'āina. Kūʻai ke kikowaena waena i ka lāʻau lapaʻau ma Kelemānia a laila hoʻonohonoho i ka hāʻawi i ke kiʻi i hōʻike ʻia e ka mea kūʻai aku.

I ka manawa like, e hōʻoia ai i ka maikaʻi o ka lāʻau lapaʻau, pono kekahi e noi no ka loaʻa kālā. Pono hoʻi e mālama i nā kiko inoa o ka inoa ma ka pale i ka inoa honua o ka lāʻau lapaʻau.

Nā hopena hōʻike hoʻokolokolo

Ua hoʻokō ʻia nā hoʻokolohua lapaʻau nui nui i ka hopena Ua hōʻike ʻia nā hoʻokolohua no ka hoʻolālā wā lōʻihi no ka hoʻohana ʻana i nā fibrates. I ka hopena, ua hōʻemi ʻia ka kolamu nui o 10% ma ka haʻahaʻa kolene haʻahaʻa o kolesterol - e 11%. I ka manawa like, ʻo ka neʻe o ka cholesterol kiʻekiʻe mau nā lipoproteins e hoʻonui i ka 15%. ʻO ka emi ʻana o nā pae triglyceride o 35% i ʻike ʻia. I ka hopena, ua hāʻule ka nui o nā make ma muli o ka maʻi puʻuwai coronary ma o 26%.

Ke hoʻomau nei ka noiʻi ʻana i kēia manawa. Ua makemake nā poʻe loea i ka hiki ʻana o ka palekana palekana me nā lipid-hoʻēmi haʻahaʻa, nā lāʻau lapaʻau no ka mālama ʻana i nā maʻi cardiovascular.

Hōʻikeʻike papaʻaina

Kūkulu ʻia nā ʻōmole resep kūikawā. Akā i ka hana, koho ʻia ka nui o kēlā me kēia no kēlā me kēia maʻi, e pili ana i kona kūlana, ke ʻano o ka hyperlipidemia, a me ka pane ʻana i ka therapy. Pili ka mea like me ka lōʻihi o ka mālama ʻana.

Katui o ke kuai ma nā lāʻau kūʻai

ʻAʻole kūʻai ʻia ʻo Bezafibrate ma Rūsia, no laila he mea nui ʻole ka manawa a i ʻole i ʻae ʻia mai ke kauka. I ʻEulopa, hiki ke kūʻai ʻia kēia mau lāʻau me ke ʻano kauka a ke kauka. Ke loaʻa nei kahi lāʻau lapaʻau e hāʻawi ana i ka lāʻau lapaʻau me ka ʻole o kēia palapala ka mea paʻakikī loa a kuhi me ka loaʻa ʻana o kahi hoʻopunipuni.

No laila, hele i kahi lāʻau lapaʻau i waho aku iā ʻoe iho, pono ʻoe e lawe i kahi papa ʻōlelo kuapoʻi mai ke kauka me ka papa ʻōlelo Latin o ka papa inoa o nā papa. Inā hiki ʻole ke kūʻai aku i ka lāʻau lapaʻau iā ʻoe iho, hiki iā ʻoe ke ʻimi i ke kōkua mai kahi kikowaena paʻa.

Ka hana lāʻau lapaʻau

Ua loaʻa iā Bezafibrat ka antiaggregatory (e hōʻemi ana i ka hopena o ka thrombosis), hypoglycemic (hoʻohaʻahaʻa i ka hoʻokahe koko), ke kūpaʻa lipid (e hoʻohaʻahaʻa ana i ka cholesterol) a me ka hana antiatherosclerotic pharmacological.

Hoʻonui ʻo Bezafibrat i ka hana o nā kinemona i komo i ka hana o ka metabolism o nā lipids (nāʻuina), ka dissimilation (hoʻokaʻawale) o nā momona i nā lipoproteins haʻahaʻa haʻahaʻa (nā pūpū paʻakikī e pili pū ana me nā momona. Mālama ka lāʻau i ka hakakā o ka lipipoli, e hōʻemi i ke kaʻi ʻana o nā alopala monobasic monobasic alobatic me kahi kaula moloka a me ka hana o lipids i loko o nā puʻuwai.

Mālama i ka synthesis o nā lipoproteins haʻahaʻa haʻahaʻa a hoʻonui i ka hoʻonui o ka hoʻomaʻemaʻe kino o lākou. Hoʻemi i ka hana o ka enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (coenzyme A) reductase. Ua hoʻomau kēia kaomi i ka synthesis o nā kolamu, no laila he kumu nui ia o nā lāʻau antisclerotic (me ka Bezafibrat).

Hoʻopili hoʻi ʻo Bezafibrate i ke kāpili ʻana o ka waikawa mevalonic, ʻo ka HMG-CoA reductase ma ka huli ʻana. Hoʻololi i nā kiko o nā lipids, ka nui o ka cholesterol (ma ke kiko, lipoprotein haʻahaʻa haʻahaʻa), akā ke hoʻonui nei i ka ʻike o nā lipoproteins kiʻekiʻe (HDL3 a me HDL2).

Hoʻemi i ka hoʻomohala koko ma o ka hana ʻana i nā papa koko ke kuleana no ka hemostasis - thromboblasts No ia kumu like, e hōʻemi ana i ka pae o fibrinogen i loko o ke koko. Hoʻalolo i ka holomua o ka atherosclerosis a me ka hoʻomaloʻo i ka loaʻa o ke koko cardiac.

Hoʻomaʻamaʻa hoʻomaʻamaʻa no nā vegetst vascular dystonia

No nā makahiki he nui ke kūleʻa ʻole ʻana me CHOLESTEROL?

Ke poʻo o ka Institute: “E haʻohaʻo ʻoe i ka maʻalahi o ka hoʻohaʻahaʻa ʻana i ka cholesterol ma o ke lawe ʻana iā ia i kēlā me kēia lā.

ʻO ka dystonia Vegetative-vascular - he mea pohihihi a nānā ka maʻi. I ka helu o kēia wā o nā maʻi, ʻaʻohe ia. ʻOi aku ka maikaʻi e ʻōlelo ʻaʻole e pili ana i ke kinona o ka dystonia vegetovascular (ʻoi aku kēia manaʻo koʻikoʻi), akā nā maʻi vegetative.

ʻAʻole ke maʻi kūʻokoʻa o ka Autonomic dysfunction, akā he hōʻailona wale nō e hōʻike ana i nā pilikia pili i ka hana ʻana o ke ʻano syʻa autonomic, nona ka hana ʻana e like me ka hanu, ka puʻuwai o ka naʻau, ke kāwili ʻana, a me ka mālama ʻana i ke koko o ke olakino.

Ua hoʻohana maikaʻi kā mākou poʻe heluhelu iā Aterol e hoʻohaʻahaʻa i ka cholesterol. Ke ʻike nei i ka kaulana o kēia huahana, ua hoʻoholo mākou e hāʻawi iā i kou makemake.

Loaʻa nā poʻe me nā pilikia o ka pūnao autonomic i nā maʻi he nui: ka ʻeha, ka puʻupuʻu, palpitations, ʻeha i ka puʻuwai, ka hopohopo, a me nā lima haʻalulu. ʻO kēia ka mea "kaulana" e hōʻike ana i nā dystonia vegetovascular, a ma ka huina keu he mau haneri o lākou. ʻO ka maʻi ʻeha, nā loli o ka hormonal i ke kino, nā maʻi o ka ʻōnaehana o ka kūina ʻana, nā pilikia me ka ʻōnaehana a me nā mea hou aku e hiki ke hoʻopiʻi i ka olakino maikaʻi.

ʻO ka mālamaʻana i ka dystonia vegetative-vascular me ka hoʻomaʻamaʻa kino ʻana i ka maʻi physiotherapy. ʻO kahi nohona hoʻonaninani hikiʻole ke hōʻemi i ka ʻōnaehana cardiovascular, hoʻemi i ka leo vascular a hoʻoulu i nā hewa ʻole o ka ʻōnaehana autonomic. ʻAʻole paʻa ke ʻano o ka maʻi lalo.

Ke Pili a me ka Noʻeau

Pono ka inu i ka lā 2-3 i ka lā no 1 / 1.5 mau papa (0.2 g) ma mua o nā meaʻai no 20-30 mau lā.

E hoʻolaʻa i nā papa (no ka hoʻohana lōʻihi) - hoʻokahi papa (0.4 g) hoʻokahi i ka lā.

Inā loaʻa, hiki i ke ʻano o ka mālama ʻana ke hoʻomau, ma hope o ka nīnau ʻana me kāu kauka.

E hoʻokuʻu i ke ʻano a me ka ʻano

Loaʻa ka lāʻau lapaʻau ʻo Bezafibrat i nā ʻāpana he 50 a 100 mau ʻāpana. Nā papa maʻamau - 0.2 g, retard (hoʻohana lōʻihi / lōʻihi) - 0.4 g.

ʻO ka papa hana nui o Bezafibrate ʻo 2-4-2- (4-chlorobenzoyl) aminoethylphenoxy-2-methylpropanoic acid (C19H20ClNO4), kahi kahi o ka waikawa fibroic.

Wahi a nā inoa inoa honua - 2- (b-para-chlorobenzoylaminoethyl) fenoxy-2-methylpropionic acid.

ʻO ka hui lāʻau lapaʻau e pili ana iā Besafibrate ka nui.

Hoʻopili pū me nā lāʻau ʻē aʻe

Hoʻonui i ka hopena o nā anticoagulants kūlike (nā lāʻau lapaʻau e hōʻemi i ka coagulation koko). ʻO ka hui pū me nā inhibitors o ka pūnaehana HMG-CoA reductase (no ka laʻana, me ka lovastatin a me nā stins ʻē aʻe) hiki i ka rhabdomyolysis (ka luku ʻana i nā nui o nā kiko o ke kikoo).

ʻO ia ke kumu e pono ai e nānā i kou kaʻiʻaha i ka wā e lawe ai i kēia lāʻau lapaʻau, a inā ʻoe e loaʻa i ka ʻeha a nāwaliwali paha i nā ʻōpū, e hoʻōki i ka lawe.

Nā hopena hopena

Hiki i ka maʻi, anorexia, puʻi, maʻi ʻaʻa, hoʻonui i ka transamiasis (mau enme i ka hoʻomau i ka pilina ma waena o ka momona a me ka momona o ka metabolism) i loko o ke koko, anemia (anemia), leukopenia (hoʻemi i ka nui o nā wahi ke keʻokeʻo ke keʻokeʻo - keʻokeʻo keʻokeʻo keʻokeʻo i loko o ke koko), cholestasis (hoʻemi ʻia ka intake bile i ka duodenum), myopathy (maʻi māhuahua maʻi), ka hemahema, nā ʻano ʻano like ʻole.

Ke hoʻoweliweli ʻole ʻia nei ka make ʻole o Bezafibrat me ka hoʻopā ʻana a me ka hōʻike ʻana o nā hopena ʻaoʻao, ʻo ia hoʻi ka dyspeptic, no laila e noʻonoʻo pono i kahi loea e pili ana i kahi kūpono o ka lāʻau no ʻoe.

Nā Hoʻohui

Hypersensitivity, cirrhosis mua hapalua, intolerance i nā mea waiwai e hoʻomake ai i ka lāʻau lapaʻau, ʻeha hōʻeha o ka naʻau (me ka ʻike ʻole ʻana o nā momona momona), nā ʻōpū, ke koʻi, ka maʻi ʻeha a me ka lactation.

ʻAʻohe ʻia ka lāʻau i nā keiki.

Noi ʻia ka lāʻau ʻo Bezafibrat e mālama i kahi wahi maloʻo, pale ʻia mai ka mālamalama a me nā keiki.

Ka awelika kumukūʻai o hoʻokahi pā o nā papa retard (hana hoʻomohala) i Lūkia - 3000 rubles.

He kumukūʻai kumukūʻai i Ukraine - 760 hryvnia.

ʻO nā analogues o Bezafibrat ʻo Bezamidin, Bezalin, Bezifal, Difaterol, Oralipin, Zedur.

E hoʻomanaʻo he hiki iā ʻoe ke koho i ka lāʻau kūpono a kūpono hoʻi no ʻoe wale nō ma hope o ka nīnau ʻana me kahi loea.

Ka wehewehe haehae

Hoʻohana ʻia ka lāʻau lapaʻau ʻo Bezafibrat e mālama i nā maʻi kūlohelohe i ka hopena ʻo ka mea ʻai a me ka hoʻomaʻamaʻa ʻaʻole i lawe mai i nā hopena. Ma muli o kāna hana pharmacological paʻakikī, pale pū ʻo Bezafibrat i nā maʻi o ka ʻōnaehana cardiovascular i pili i ka hoʻokumu ʻia ʻana o ke kīwaha koko a me ka huehue o nā kīʻaha koko.

ʻO kēlā hopena maikaʻi o ka lāʻau lapaʻau ma muli o ka mea e hana ia ma ka enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (coenzyme A) reductase. ʻO kēia kahi kinakē e hōʻeha ai i ka hōʻailona o ke kolala, no laila ke nānā pono ka nui o nā lāʻau antisclerotic.

ʻO ka maʻamau, ʻo 0.2-0.3 mau manawa i kuhikuhi ʻia i ʻekolu manawa i ka lā ma mua o ka ʻai ʻana a i ʻole 0.4 g i hoʻokahi manawa i ka lā (retard tablets, i.e. nā papa no ka mālama ʻana i ka lōʻihi o ka mālama ʻana).

ʻAʻole pono e hoʻolālā i ka nui o nā lāʻau i lawe ʻia i ka manawa like me ka bezafibrate, ʻo ia ka mea e hoʻonui ai i ka hopena o nā anticoagulants kūlohelohe, a hui pū ʻia me nā inhibitors HMG-CoA reductase hiki ke hōʻeha i ka rhabdomyliosis, kahi maʻi i hoʻopau ʻia nā cell o ke kino ʻōpū o ke kanaka.

Contraindicated ka lāʻau lapaʻau i nā wahine hāpai a lactating, nā keiki a me nā poʻe e hōʻeha nei i nā maʻi koʻikoʻi o nā pūpū, nā māpuna, ka hāpū paleka, a me ka poʻe me ka hoʻomehana kū ʻole ʻana i nā mea pākahi a i ʻole ka hopena holoʻokoʻa holoʻokoʻa.

I ka hoʻohui ʻana i nā maʻi o ka māhina, hiki i nā hopena ʻili e pili ana i nā pilikia o ke kaomi o ka digestive - nausea, ka luaʻi, ka hopena, ka anorexia, cholestasis, nā maʻi o ka kuʻina a me ka hoʻopihapiha o ka mana o ke koko - anemia, leukopenia, etc., hiki mai.

Ke hoʻomau nei ʻoe i ka mālama ʻana me Bezafibrat, mai poina e pili ana i ka meaʻai, ka hoʻomaʻamaʻa kūlohelohe i kūpono iā ʻoe a me ka mālama pono ʻana i ka kūlana o kou kino - ka nānā ʻana i ka manawa a me ka kipa ʻana aku i ka lumi ultrasound e hiki iā ʻoe ke hoʻopakele iā ʻoe mai ka maʻi pālolo a me nā hopena ʻē aʻe o ka lāʻau Bezafibrat.

Nā kumuhana ākea o ka physiotherapy i ka IRR

ʻO nā hana Physiotherapy me ka vegetative-vascular dystonia kahi hana maʻalahi a maikaʻi hoʻi e hoʻopau ai i nā hōʻailona o ka maʻi. I ka manawa e hoʻomaka ai kou kino e loaʻa ka nui o ka hana kino, ka hele ʻana o ka cardiovascular a me nā ʻōnaehana i loko o kahi kaulike: ke kaumaha nei a me ka hōʻemi ʻana o ka puʻuwai, nāwaliwali a me nā leʻaleʻa maikaʻi, hele aku ka loli ʻana o ka naʻau no ka maikaʻi aʻe.

ʻO nā ʻano o nā ukana i kūpono i nā poʻe me ka dystonia vegetovascular:

• e hele pololei ana
• ʻauʻau
• aerobics wai
• hili
• hula
• aerobics (me ʻole nā ​​mana mana),
• hoʻomaʻamaʻa i ka mahiʻai (me ka māmā māmā),
• Tabata (me kekahi mau kiʻi kokoke)
• ʻĀina yoga

Ke komo nei i ka hoʻonaʻauao kino e hoʻoikaika i ka ʻōnaehana cardiovascular, pono ʻoe e ʻike i ke ana. Hoʻohana ʻia nā mea hana hana nui e pono ai e pōmaikaʻi i kahi kino hoʻomākaukau ʻole. Hoʻohanaʻike i nā lāʻau lapaʻau i ka dystonia vegetative-vascular e hoʻopili i nā mea maʻamau a me ka nui ʻole. Hiki i ka hana pilikino ke hōʻeha i ka hōʻeha, ka ʻeha, a me ka nāwaliwali ʻana i loko o kahi kanaka me ka dystonia vegetative-vascular.

Inā hoʻomaʻamaʻa ʻoe i nā hale loko, pono e hōʻuluʻulu maikaʻi ʻia. Ma kahi o ka nānā ʻana i ka hoʻomaʻamaʻa, mai poina e pili ana i ka hanu ʻana, ʻaʻohe hihia e paʻa.

Mai poina e pili ana i nā hana kakahiaka i kēlā me kēia lā! He mea lawa ke hana i ka wanaʻao kakahiaka no 15 mau minuke. Ma hope o ka waiho wale ʻana i ka ikaika, ʻaʻole ka momona. Inā ma hope o ka hoʻomaʻamaʻa ʻana i nā hōʻailona o ka maʻi, ua hoʻāʻo e hōʻemi i ka kaumaha a nīnau aku i kahi kauka.

Hoʻomaopopo ʻia e hoʻomaka i kekahi hana me ka hele wāwae. I ka wā mahana, mai hana i nā neʻe wikiwiki, e lele ana i nā lima a me nā wāwae me ka nui nui. Pono e hoʻonui ikaika i ka hoʻomaʻamaʻa. I ka hopena o ke kau, e hoʻolohe i ka hanu a me ka hoʻomaha.

ʻAʻole pono e mālama i kahi palapala kikoʻī o ke kaomi, ka puʻuwai naʻau a me ka nui o nā hana e hoʻomaʻamaʻa ʻia. Hiki i ka poʻe me ka vegetovascular dystonia ke ulia i ka hopohopo, no laila ka mea nui i ka hoʻopaʻa ʻana iā lākou iho a hiki ke hōʻeha i ka mokuʻina o ka ʻōnaehana. E koho i kēlā me kēia mau hāmeʻa hāmeʻa āu e makemake ai no ka lawe ʻole mai ʻoe i nā manaʻo ʻino.

ʻO ka hale hana hōʻoluʻolu me ka VSD

ʻO kekahi o nā kumu o nā maʻi autonomic ka nele o ka oxygen i ke kino. ʻIke ʻia ia mai kahi ʻano hectic. I ke kūlana kaumaha, piʻi nui ke kaumaha, hele pinepine ka pulse, a me ka hanu hou aku.

Ke manaʻo nei ʻoe e māhuahua nei ka ulu ʻana o ke aʻai, e hoʻāʻo e hana mālie a me ka hohonu, e kāohi i kāu inhalation a me nā ea. ʻAʻole hiki iā mākou ke ʻalo i ka hoʻokaumaha ʻana a i ʻole ka helu ʻana o ka puʻuwai, akā ʻo ka pale ʻana i kā mākou hanu he ala kūpono ia no nā poʻe a pau e hoʻi i ko lākou kino i kahi kūlana o ke kaulike.

Pono ʻoe e aʻo i ka hanu kūpono. I kēlā me kēia lā maʻamau, ʻaʻole mākou e hoʻohana piha i nā hiki o kā mākou māmā, ke hana wale lākou ma kahi o 20%. Kōkua kekahi mea hanu i ka hoʻonui ʻana i ka hoʻokomo ʻana o ka pūnaehana hanu holoʻokoʻa.

He aha nā mea hanu kūpono? ʻO ka mea mua, pono ia e lilo i mea superficial, akā paʻa - ka umauma, ʻōpū a me ka diaphragm pili. Pono ʻoe e hanu ma ka ihu, ʻoi aku ka lōʻihi o ka manawa ma mua o ka hoʻonā. Hoʻopili maikaʻi, hoʻololi i waho me ke kaumahaʻole. I ka wā e hōʻoki ai i ke kino, i mea e pale ʻole ai i ka pōkole loa o ka hanu, hiki iā ʻoe ke hanu i ka manawa like me ka waha a me ka ihu a i ʻole ke hū ʻia ma o ka ihu, a hamo ʻia ma ka waha.

I ka manawa o kahi e hana ai e pono ai ʻoe e hanu e like me ke ʻano o nā neʻe. No ka laʻana, pololei lākou, hohola i ko lākou umauma a hāpai i ko lākou mau lima - ua kiʻi lākou. Hoʻokomo ʻia, hoʻopili ʻia ko lākou mau lima - hoʻoikaika. Hana i ka noʻeau ma ka hoʻomaka ʻana o ka paipai. Inā ʻaʻole ʻoe e hoʻonohonoho i ka neʻe i ka hanu, hele koke ka luhi, a na nā ʻiʻo a me ka lolo me ka oxygen.

Hoʻohana nā hana hanu me ka vegetovascular dystonia i ka hoʻokūkū i ka maʻi hyperventilation pulmonary, e kū ana i ka wā o ke kāʻei o ka noʻonoʻo a me ka wā e hopohopo pinepine nei nā poʻe maʻi me VSD. Pā pū kekahi me nā pilikia o ka hanu e pili ana i ka hiki ʻole o ka hanu a me ka manaʻo ʻole o ka nele o ka ea.

ʻO kahi hoʻonohonoho o ka hana hanu mea maikaʻi loa i hana ʻelua i ka lā a lilo i ʻano. Ke hoʻomaʻamaʻa pinepine nei, e hoʻomaka ka hanu pololei ʻana, ʻaʻole wale nō i ka wā o nā papa, akā i ka nohona o kēlā me kēia lā. Hiki i ke kūlana o ke kino ke ʻano: e noho ana, e noho ana, e kū ana, inā ʻaʻole ʻoe e hōʻoluʻolu i ke ʻano ʻana o ka hanu.

Nā koho no nā hana hanu:

• ʻO ka hanu ma ka ihu. ʻO ka mea mua mākou i hanu ai me nā pūloko ʻelua, a laila huli i kēlā me kēia (kaki i kekahi i kahi lima). Pono ka hanu, paʻakikī, akā me ka ʻole o ka loaʻa ʻole o ka ea a me ka dizziness.
• ʻŌpū hanu. Mālama mākou i ka neʻe ʻole ʻana o ka umauma, pale nui ka ʻōpū a huki ʻia i ka kani o ka hanu. Hiki iā ʻoe ke kau i kekahi lima ma kou umauma a me kekahi ma kou ʻōpū e pale ai iā ʻoe iho.
• ʻO ka hanu hanu. Maanei mākou e kāohi ai i ka ʻōpū o ka ʻōpū, hana mākou me ka umauma. I ka wā o ka hoʻopihapiha, hoʻomoʻi a hoʻāla i ka umauma e like me ka hiki, aʻo ka mea e hoʻolako ʻia, kaomi
• Mālama piha. Hoʻokomo pū ka umauma a me ka ʻōpū i ka manawa like. He hana paʻakikī loa kēia, pono e hana ʻia a i ʻike ʻia ʻo ia ma mua. ʻAe ke ʻano o ka hanu piha ʻana: me ka huluhulu ʻana me ka umauma, a laila me ka ʻōpū, a me ka hanu ma ke ʻano heʻe. Pā lākou i ka lewa mai ka ʻōpū, hoʻokuʻu i ka umauma.

Hana ʻia nā hana āpau 8-12 mau manawa, mai lawe ʻoe iā ʻoe iho i ka momona a me ka maʻi kaumaha.

ʻO yoga ma VSD

ʻO ka yoga, inā e hana maʻamau ʻoe me ka hoʻomaopopo ʻana, e hōʻoluʻolu i nā hōʻailona o ka dystonia vegetovascular a ke kōkua nei i ka hoʻohālikelike ʻana i kēlā me kēia lā. Hoʻokomo ka yoga i kahi ala komo i ke hoʻoikaika kino kino a me ka olakino. ʻAʻole wale kēia he mau hana hoʻohua, akā he ʻōnaehana kai, nā hana hanu, a me ka noʻonoʻo noʻonoʻo.

Pono nā kānaka me VVD e hoʻomaka i nā papa yoga, ʻaʻole koke i ka puʻuwai paʻakikī. Inā ʻoe i loko o kahi pūʻulu, e hoʻolohe i kou kino, a ʻaʻole kiai. ʻAʻole pono nā mākaʻaka e hakakā no kahi kaila i wehewehe ʻia ʻo ka hanu.

ʻLelo i ka yoga me ka vegetovascular dystonia i kēia mau mea i lalo:

• Asanas (postures kūikawā o ke kino). Pono lākou e koho ma muli o ke ʻano o ka vegetstascular dystonia. ʻO nā poʻe me ka hoʻokahe koko haʻahaʻa (ke ʻano hypotonic VVD) e hōʻike ʻia ʻana o ka asanas, deflections, kū i ke kūlana, hana hōʻona. E hoʻohana ʻia ka pauku ʻo Surya Namaskar. I kēlā me kēia kūlana, e noho no ka nui o nā ʻōpū hanu (ʻekolu a i ʻole), e pili ana i kou manaʻo. ʻO nā mea maʻi me kahi ʻano hypertensive o VSD e hoʻomaka i ka yoga me ka hoʻomaha (no ka laʻana, me kahi paila kino). Pono e hoʻomaʻamaʻa ʻia ka hoʻomaikaʻi ʻana i kahi asanas i ka inclines, akā e makaʻala ʻoe e pale ʻole hohonu i lākou me lākou. E hana ana ʻo Asana me ka hoʻomoe ʻana a me ka noho ʻana, e hoʻomaikaʻi ai lākou i ke ʻano o ka kuʻina a me ka hana ʻana. Me ke ʻano o ka puʻuwai o ka VSD, hiki iā ʻoe ke hoʻohana i nā ʻano āpau o asana, akā, pono ʻoe e nānā i kou pae o ke koko a me ka pulse.

• Bandhi (mau kīʻaha kūwili, ka hooweliweli ʻana o kekahi mau pūʻulu mākoi). Hoʻohana maikaʻi lākou i ka pūnaehana autonomic maikaʻi a hoʻomaikaʻi i ka kaila o ke koko o nā kino o loko. Hiki iā ʻoe ke hoʻohana iā lākou wale nō a i ʻole me ka hoʻohui ʻana me ka asanas.

• Pranayama (hana hanu). Hoʻohana maikaʻi loa lākou no nā poʻe me kahi ʻano hypotonic o VSD. Hōʻike ʻia lākou e noʻonoʻo i ka paipai ʻana, ʻaʻohe leo maluhia i loko o ko lākou mau umauma. Pono nā maʻi maʻi maʻi hypertensive e pili pono i ka luhiluhi ka lōʻihi, ua ʻōlelo ʻia lākou iā Chandra-bhedana pranayama.

Hoʻohana ka hana meditative (ka nānā ʻana i ke kaʻina o ka hanu, ka mantra, ʻike ʻia ʻana) he pono no VVD, hoʻonui lākou i ke kūmau kino, hoʻālo i ke koko, a hoʻopau i ka hopohopo.

No laila, me ka vegetovascular dystonia, hiki iā ʻoe ke komo i loko o nā hāmeʻa a pau loa. Hiki iā ʻoe ke koho i nā hana a ka ʻuhane e waiho ai a hauʻoli i nā hana āpau. Mai poina e hoʻolohe i kāu mālama pono a hoʻokaʻawale i nā ʻano maikaʻi ʻole - ʻo ia ka kumuhana koʻikoʻi o ka hoʻokūkū aʻoaʻo i loko o ka vegetovascular dystonia.

E kōkua ke ola kino e hana wale nō e pale ai i ka maʻi, akā e hoʻomaʻamaʻa i nā nohona o kēlā me kēia lā, a me nā manaʻo maikaʻi maikaʻi he pale maikaʻi loa o nā pilikia a me nā puʻuwai.

Nā hōʻailona a me nā contraindications no ke hoʻohana

Mālama kēia lāʻau lāʻau lapaʻau koko, hoʻohaʻahaʻa i ke koko koko, hoʻohaʻahaʻa i ka cholesterol a pale i ka hoʻomaka ʻana o ka atherosclerosis.

Ma ke komo ʻana i ke kino, hoʻōla ka lāʻau i ka hana o nā enzyme i hoʻopili ai i ka hana lipid metabolism, hoʻonui i ka ʻaki o nā lipoproteins haʻahaʻa haʻahaʻa.

Hiki i ka lāʻau lapaʻau ke hoʻemi i ka ukana ma luna o nā ate, ka mea maʻamau e kū nui me ka kolamu kiʻekiʻe. Ke hoʻolōʻihi nei i ka hana o nā lipoproteins haʻahaʻa haʻahaʻa a hoʻomaʻemaʻe i ke kino o lākou iā lākou i kahi manawa pōkole.

Ua hoʻohana maikaʻi kā mākou poʻe heluhelu iā Aterol e hoʻohaʻahaʻa i ka cholesterol. Ke ʻike nei i ka kaulana o kēia huahana, ua hoʻoholo mākou e hāʻawi iā i kou makemake.

Ma ka hoʻohaʻahaʻa i ka lipoproteins haʻahaʻa haʻahaʻa, e hoʻonui ana hoʻi i ka lipoproteins kiʻekiʻe. Mālama i ka hoʻomaka ʻana o nā māhina o ke koko, e hoʻohaʻahaʻa ana i ke koko, e hoʻomaikaʻi i ka hoʻolako ʻana o ka naʻau.

Loaʻa kēlā mau ʻōuli i ka hoʻohana ʻia:

1. ʻO ka Hyperlipoproteinemia o nā ʻano āpau.
2. Hāpopo.
3. Hypertriglyceridemia.
4. Hāpai i ka lipid molihine.
5. Loaʻa nā hopena i ka pancreatitis.
6. ʻOi momona.
7. E hōʻemi i ka nui o nā hoʻouka ʻana o angina.
8. Loaʻa i ka paleʻana i ka hoʻohaʻahaʻa.
9. Naʻi maʻi mellitus.
10. ʻO nā ʻalopena metabolic.

Hoʻohana ʻia ka hoʻohana ʻana i ka lāʻau i kahi hihia wale nō o ke ʻano hoʻoikaika kino a me ka meaʻai kūikawā. Hiki ke koho ʻia kahi loea. Ke hoʻohana nei i ka lāʻau lapaʻau me ka ʻike ʻole o ke kauka hiki ke alakaʻi i ka ulu ʻana o ke kūlana. ʻOiai ʻo nā pōmaikaʻi, loaʻa nā contraindications. Lā ʻia ka lāʻau lapaʻau ʻana ma ka hihia o:

• ka ahalike kanaka kū hoʻokahi i nā ʻāpana,
• cirrhosis mua loa,
• haaheo
• nā maʻi ākea o ka puʻuwai (koe wale nō ka momona momona),
• maʻi maʻi koʻikoʻi
• maʻi maʻi maʻi
• hapai a me lactation,
• mākaʻikaʻi.

Ke lawe ʻia nā lāʻau lapaʻau ʻē aʻe i ka ʻokoʻa, pono ʻoe i lalo o ka mākaʻi o kahi loea. Hiki i ka Fibrate ke hoʻonui i ka hopena o nā lāʻau lapaʻau e hōʻemi i ka coagulation koko, rhabdomyosis (ka luku ʻana i nā nui o nā pona) hiki ke hoʻohana pū me nā statins. Ma ka hihia o ka hoʻokele ʻana i nā lāʻau ʻē aʻe, pono e ʻike ʻia ke kauka e pili ana i kēia.

Inā i ka manawa o ka mālama ʻana i nā makahiki o ko ke ola olakino, ʻoi aku ka maikaʻi o ka hoʻopili ʻana i kahi ʻoihana lapaʻau.

ʻO nā mea maʻamau o ka lāʻau

ʻAʻole wale ʻo Bezafibrat ka lāʻau lapaʻau e hiki ke hōʻemi i ka cholesterol a pale i ka atherosclerosis maʻi.

Inā kūpono, hiki ke loli i ka lāʻau lapaʻau. ʻOi aku ka nui o ka lāʻau lapaʻau ma mua o hoʻokahi analogue, hiki iā ia ke lilo i kahi kūhelu, hana maoli ʻole.

Aia, ʻokoʻa wale nō nā lāʻau lapaʻau o kēia ʻano ma ka māhele kumukūʻai, a aneane like ka hopena.

Aia nā ʻāpana:

• Bezamidine - nā kumukūʻai mai 400 rubles.
• Besalin - ke kumukūʻai mai 500 rubles.
• Difaterol - nā kumukūʻai mai 800 rubles.
• Zedur - nā kumukūʻai mai 500 rubles.
• ʻO Oralipin - nā kumukūʻai mai 1000 rubles.
• ʻO Cholestenorm - nā kumukūʻai mai 580 mau rubles.

Hiki ke ʻano ke kumukūʻai o nā lāʻau lapaʻau, e like me ka nui a me ka lāʻau lapaʻau. I mea e kūʻai ai i ka hapa nui o kēia mau lāʻau, pono ʻoe i ka lāʻau lapaʻau.

Hoʻokomo ʻia ka intake o ka lāʻau a me kāna hana hou e ka loea wale nō, inā ʻaʻole paʻakikī ke ʻano.

Pono e hoʻohui pū me nā lāʻau lapaʻau me nā haʻuki, hoʻolaʻa kūpono a me ka hōʻole ʻole mai ka hana ʻino, no ka mea, nā mea hoʻopau lākou i nā kīʻaha koko. E ʻoi aku ka hopena o nā lāʻau lapaʻau ʻole i ka hopena o ka lāʻau ma ke kino, a e loaʻa ʻole paha nā hopena kūpono.

Ma hope o kēia mau lula maʻalahi e pili ana i nā pilikia olakino. Ua waiho aku nā mea hoʻohana ma mua o ka loiloi loiloi maikaʻi e pili ana i ka hiki ʻana o kēia mau mea hana.

Hāʻawi ʻia ka ʻikepili e pili ana i ka mālama ʻana o ka atherosclerosis i ke wikiō i kēia ʻatikala.