Hoʻopau ka Actrapid NM Penfill - hopena > He hoʻomaʻemaʻe a me ke pale aku

ʻO ka maʻi diabetes mellitus type 1, type 2 diabetes mellitus: ke kū'ē o ke kū'ē i ka lāʻau hypoglycemic oral, ke pale kino i ka maʻi hypoglycemic oral (hui pūnaʻi),

maʻi ketoacidosis maʻi, ketoacidotic a hyperosmolar coma, diabetes mellitus i loaʻa i ka wā o ka wā o ka hapaha (inā ʻaʻole maikaʻi ka hopena o ka papa),

no ka hana ma waena o nā mea maʻi me ka maʻi mellitus no ka maʻi maʻi e hele pū ana me ke kuni nui, me nā hana hōʻino e hiki mai ana, nā hōʻeha, ka hānau ʻana, ka maʻi metabola, ma mua o ka hoʻololi ʻana i ka mālama ʻana me ka hoʻomākaukau ʻana i ka hoʻomākaukau ʻana i ka insulin.

E hoʻokuʻu i ke ʻano, ka hoʻonohonoho ʻana a me ka pōpoki

ʻO ke kūleʻa no ka inikō ua ʻoliʻoli, ʻaʻole ka pala.

1 ml
hoʻohuihui kūmole (human genetic engineering)	100 IU *

Nā mea hoʻoweliweli: zinc chloride, glycerol, metacresol, hydrochloric acid a me / or sodium hydroxide solution (e mālama i ka pH), ka wai d / i.

* 1 IU pili i ka 35 gg o ka inamine manu anhydrous.

3 ml - mau pahu aniani (5) - nā pā o ka pahu paʻi.

Ka hana lāʻau lapaʻau

ʻO Actrapid ® NM kahi hana hoʻonaninani hana pōkole e hana ʻia ana e ka biotechnology DNA recombinant me ka hoʻohana ʻana i ka mana Saccharomyces cerevisiae. ʻO ka emi ʻana o ke kaʻe o ka glucose i ke koko e kū ana ma muli o ka hoʻonui o kāna kaomi intracellular ma hope o ka hoʻopaʻa ʻana i ka insulin i ka receptors insulin i nā uaua adipose a me ka hoʻohaʻahaʻa like ʻana i ka hopena o ka hana glucose i ka ate. Ka hoʻōla ʻana o ka glucose glucose glucose (a hiki i ka 4.4-6.1 mmol / l) e ka hoʻomōlohelohe o Actrapid ® NM i nā mea mālama maʻi maʻi e hoʻomaikaʻi ana i nā maʻi maʻi (204 nā mea maʻi me ka maʻi mellitus a me ka 1344 me ka maʻi kuhi ʻole o ka maʻi mellitus) i loaʻa ka hyperglycemia (plasma glucose ulu> 10 mmol / L), hoʻemi iki ka make ma ka 42% (4.6% ma mua o 8%).

Hoʻomaka ka hana a ka lāʻau Actrapid ® NM i loko o ka hapalua hola ma hope o ka hoʻokele ʻana, a ʻo ka hopena nui loa e ʻike ʻia i loko o 1.5-3.5 hola, ʻoiai ka lōʻihi o ka hana ma kahi o 7-8 hola.

ʻO ka ʻikepili palekana preclinical

Ma nā haʻawina preclinical, me nā haʻawina palekana palekana pharmacological, nā noiʻi toxicity me nā papa ʻōiwi hou, nā noiʻi o ka genotoxicity, ka maʻi carcinogenic a me nā hopena maʻi hona i ka pōpopili, ʻaʻole ʻike ʻia ka pilikia kūikawā i ke kanaka.

Lapaʻau lāʻau

ʻO T 1/2 o ka insulin mai ke kahawai he mau minuke wale nō.

ʻO ka lōʻihi o ka hana o ka hoʻomākaukau ʻana o ka insulin no ka nui o ka absorption, ka mea e hilinai ana i nā mea he nui (no ka laʻana, ma ke ʻano o ka insulin, ke ʻano a me kahi wahi o ka hoʻokele ʻana, ka mānoanoa o ka momona momona a subcutaneous a me ke ʻano o ka maʻi mellitus). No laila, ʻo nā hāmole pharmacokinetic o nā insulin e kau i ka nui o ka iter- a me intuc-individual fluctuations.

Loaʻa ka C max o ka insulin i ka plasma i loko o 1.5-2.5 mau hola ma hope o ka hoʻokele sc.

ʻAʻohe mea i ʻōlelo ʻia e pani ʻia i nā protein plasma e ʻike ʻia, me ka hoʻoleʻa o nā antibodies i nā insulin.

Hoʻopili ʻia ka insulin o ke kanaka e ka insulinase a i ʻole nā ʻeneka lawena ʻaʻiwahī, a i ʻole pū kekahi ʻia e ka protein disulfide isomerase.

Ua manaʻo ʻia aia aia i loko o ka molekala o ka insulin kanaka he nui nā wahi o ka cleavage (hydrolysis), eia nō naʻe, ʻaʻohe mea ʻano o nā metabolites i hoʻokumu ʻia ma muli o ka palaki i ka hana.

Ua hoʻoholo ʻia ʻo T 1/2 e ka helu o ka komo ʻana mai ka kiko subcutaneous. No laila, T 1/2 ʻoi aku ke ana o ka kaomi ʻana, ma mua o ke ana maoli o ka hoʻoneʻe ʻana i ka insulin mai ka plasma (T 1/2 o ka insulin mai ke kahe koko a he mau minuke wale nō). Ua hōʻike ʻia nā noiʻi ʻo T 1/2 mau ma kahi o 2-5 hola.

Na keiki a ʻōpio

Ua aʻo ʻia ka ʻōlelo lapaʻau ʻo ka pharmacokinetic o ka lāʻau Actrapid ® NM i loko o kahi pūʻulu liʻiliʻi o nā keiki me ka maʻi maʻi (18 mau kānaka) 6-12 mau makahiki, ʻo ia hoʻi ka ʻōpio (ʻo ka makahiki 13-17 mau makahiki). ʻOiai ke ʻike pono ʻia nā kiʻi i loaʻa, akā naʻe ua hōʻike lākou i ka mole pharmacokinetic o Actrapid ® HM i nā keiki a me nā ʻōpio ua like like ia me nā pākeke. Ma ka manawa like, ua hōʻike ʻia nā ʻokoʻa i waena o nā pūʻulu o nā makahiki he nui e kahi hōʻailona e like me C max, e hōʻike hou ana i ka pono no ke koho ponoʻī i kū hoʻokahi.

Ka hoʻoponopono ʻia ʻana

Ke kuhikuhi ʻia nei ka lāʻau lapaʻau no SC a / i ka hoʻolaha.

Koho ʻia ke ʻano o ka lāʻau lapaʻau hoʻokahi, me ka noʻonoʻo ʻana i nā pono o ka mea maʻi.

ʻO ka pinepine, nā koi o ka insulin mai ka 0.3 i ka 1 IU / kg / lā. ʻOi paha ka pono o kēlā me kēia lā i ka insulin i ka mea maʻi me ka pale o ka insulin (no ka laʻana, no ka wā ʻōpiopio, a me ka poʻe maʻi me ka huelo), a e hoʻohaʻahaʻa hoʻi i nā mea maʻi me ka hoʻomaha o ka hana endogenous insulin.

Hoʻohana ʻia ka lāʻau lapaʻau i 30 mau minuke ma mua o kahi pāʻina a i ʻole kahi kīmona i loaʻa nā kīmona. ʻO Actrapid ® NM kahi hana pōkole hana pōkole a hiki ke hoʻohana pū ʻia me ka insulins lōʻihi.

ʻO Actrapid ® NM e mālama pinepine ʻia ka subcutaneously ma kahi o ka pā o ka ʻōpū kuʻuna. Inā kūpono kēia, a laila hiki ke hana ʻia nā inikini ma ka ʻūhā, wahi a gluteal a i ʻole ke kahalaha o ka io o ke ʻano o ka poʻohiwi. Me ka hoʻopuka ʻana o ka lāʻau lapaʻau i ka ʻāina o ka paia o ka ʻōpū o ka naʻau, ʻoi aku ka wikiwiki o ka hoʻouka ʻana ma mua o ka hoʻomaka ʻana i nā wahi ʻē aʻe. Inā hana ʻia ka ʻōlohelohe i loko o kahi pānaʻi i pālahalaha nui, hōʻemi ʻia ka hopena o ka ʻaha hoʻokaumaha ʻole intramuscular o ka lāʻau. Pono ka noho iki ma lalo o ka ʻili no ka liʻiliʻi o 6 kekona, e hōʻoiaʻiʻo ana i kahi maʻi piha. Pono e hoʻololi mau i ka pūnaewele injection i loko o ka wahi anatomical i mea e hōʻemi ai ka hoʻonaninani o ka lipodystrophy. Hiki iā Actrapid ® NM ke komo i loko o / i loko a hiki ke hana ʻia kēia mau hana e nā loea lapaʻau.

I loko o / ma ka hoʻokomo 'ana i ka lāʻau Actrapid ® NM Penfill ® mai ka pahu pahu wale nō e ʻae ʻia ma kahi wale nō o ka hūnā ʻole i nā hole. I kēia hihia, pono ʻoe e lawe i ka lāʻau i loko o kahi syringe insulin me ka ʻole o ka hoʻokomo ʻana o ka ea a hoʻohana i ka ʻōnaehana infusion. ʻAʻole pono kēia hana e nā kauka.

Hoʻolālā ka Actrapid ® NM Penfill ® no ka hoʻohana ʻana me nā ʻōnaehana inikua o Novo Nordisk a me nā pono ponoʻī o NovoFine ® a i ʻole nā manamana NovoTvist ®. Pono e nānā ʻia nā ʻōlelo kikoʻī no ka hoʻohana a me ka hoʻokele ʻana o ka lāʻau lapaʻau.

ʻO nā maʻi e like me ka maʻi hopohopo a hele pū ʻia me ke kuni, e hoʻonui pinepine i ke kino o ka maʻi o ka insulin. Hiki ke koi ʻia ka hoʻoponopono ʻana inā he maʻi nā mea maʻi i nā maʻi, nā ate, ka hana adrenal function, pituitary a i ʻole thyroid gland.

Hiki pū paha ke pono no ka hoʻoponopono hoʻoponopono ʻana i ka wā e hoʻololi ai i ka hana kino a i ka ʻai maʻamau o ka mea maʻi. Hiki ke koi ʻia ka hoʻoponopono ʻana i ka neʻe ʻana i ka mea maʻi mai kahi ʻano like ʻole o ka insulin i kekahi.

Nā hopena hopena

ʻO ka hanana maʻamau e kū nei me insulin he hypoglycemia. I loko o nā hoʻokolohua lapaʻau, ʻo ia hoʻi i ka wā o ka hoʻohana ʻana i ka lāʻau ma hope o ka hoʻokuʻu ʻana i ka mākeke mea kūʻai, ua loaʻa i ka nui o ka ulu ʻana o ka hypoglycemia kūlike i ka nui o ka mea hoʻomanawanui, ka pākī o ka nui o ka lāʻau, a me ka pae o ka kaohi glycemic.

I ka hoʻomaka mua o ka inika insulin, hiki i nā hewa refractive, edema a me nā hopena ke hele mai ma ka pūnaewele injection (me ka hōʻeha ʻana, ʻulaʻula, hives, ʻehaʻīwā, kūwili, ʻaʻai a hōʻeha i ka wahi ʻomaʻomaʻi). Kēia manawa iki kēia mau hōʻailona. Hiki i ka hoʻomaikaʻi wikiwiki ʻana i ka mālama glycemic ke alakaʻi i kahi kūlana o ka "neuropathy eha ʻeha," i ʻeli pinepine ʻia e ia. Ka hoʻonāukiuki ʻana o ka inikini insulin me ka hoʻomaikaʻi koʻikoʻi i ka kaohi o ka mea laʻala kalaiwa hiki ke alakaʻi i kahi wā pōkole i ke kūlana o ka maʻi retinopathy maʻi, ʻoiai ka lōʻihi o ka hoʻomaikaʻi ʻana i ka glycemic control hōʻemi i ka hopena o ka holomua o ka maʻi retinopathy diabetes.

ʻO nā hopena āpau i hōʻike ʻia ma lalo nei, e pili ana i ka ikepili mai ka mau kauaka maʻi, e ʻāʻawale ʻia e like me ke alualu ʻana i ka hanana e like me MedDRA a me nā ʻōnaehana organ. ʻO ka hanana o nā hopena ʻokoʻa ka mea i wehewehe ʻia:

pinepine pinepine (≥ 1/10),

pinepine (≥ 1/100 i nā ʻōnaehana Pūnaewele:

pinepine - urticaria, ʻiliʻili o ka ʻili,
pākaʻi ʻole - kūʻai ʻanaphylactic.

ʻO ka huʻihuʻi me ka meaʻaiʻaiʻai:

pinepine pinepine - hypoglycemia.

Nā kuhihewa o ka ʻōnaehana nerve:

pinepine - - neuropathy peripheral ("neuropathy pain" ".

Nā kuhihewa o ke io o ka hihiʻo:

- maʻamau
ākea loa - retinopathy diabetic.

Nā pilikia mai ka ʻili a me nā kiko kikoʻī.

pinepine - lipodystrophy.

ʻO nā maʻi maʻamau a me nā pilikia i ka pūnaewele hōʻola:

- pinepine i ka wahi o ka ʻōiwi.
pinepine - edema.

ʻO ka ho'ākāka o kēlā me kēia ʻino maikaʻi ʻole:

Loaʻa nā hopena maʻamau o ka hypersensitivity maʻamau (me ka ʻili o ka ʻili o ke kino, ʻeha, ʻoni ʻana, ʻeha ka gastrointestinal, angioedema.

ʻO ka hypoglycemia ka hopena maʻamau loa. Hiki ke hoʻomohala inā he kiʻekiʻe loa ka nui o ka inika e pili ana i ka pono o ka insulin. Hiki i ka hypoglycemia koʻikoʻi ke alakaʻi i ka nalowale o ka ʻike a / a i nā mea hoʻi i koi ʻia, i ka wā i hōʻeha ʻole a hoʻoweliweli paha i ka hana o ka lolo, a he make. Nā hōʻailona o ka hypoglycemia, ma ke ʻano he kānāwai, hoʻomohala koke. Hiki i kēia me ke "hau maloʻo", pallor o ka ʻili, nui ka momona, ka hopohopo a me ka haʻalulu, hopohopo, ʻeha ʻole, a nāwaliwali ʻia, nāwaliwali, ka hōʻemi ʻana i ka waila, ka hiamoe, ka pōloli, ka hiʻona blurred, hōʻeha, ka lua, a me ka wikiwiki puʻuwai puʻuwai.

ʻO nā hihia heʻe o ka lipodystrophy i hōʻike ʻia. Hiki i ka lipodystrophy ke hoʻomohala ma ka pūnaewele injection.

ʻŌpū a me ka lactation

ʻAʻohe mea paʻa i ka hoʻohana ʻana o ka insulin i ka wā hapai, no ka mea, ʻaʻole i kū ka insulin i ka papale placental.

ʻO nā hypoglycemia a me hyperglycemia, kahi e hiki ai ke hoʻomohala i nā hihia i koho ʻia i hiki ke koho ʻia, e hoʻonui ai i ka hōʻeha o ka maʻi male a me ka make o ka fetal. ʻO nā wahine hāpai i ka maʻi maʻi e nānā pono ʻia i ka wā o ko lākou hānau ʻana, pono lākou e hoʻonui i ka kaohi o ke kaila glucose o ke kō, nā loina like e pili ana i nā wahine e hoʻolālā nei i kahi hāpai.

Ka pono o ka insulin e hoʻohaʻahaʻa i ka mea hoʻomaʻama mua o ka hapai a hoʻonui pinepine ʻia i ka trimesters lua a me ke kolu.

Ma hope o ka hānau keiki ʻana, ka pono o ka insulin, e like me ke lula, ua hoʻi hou i ka pae i nānā ʻia ma mua o ka wā hapai.

ʻAʻohe mea paʻa i ka hoʻohana ʻana o ka lāʻau Actrapid ® NM i ka wā o ka hōʻoki ʻana. Ke pale nei i ka maʻi insulin no ka hānai hānai ʻaʻole i pilikia no ke pēpē. Eia naʻe, pono i ka makuahine ke hoʻoponopono e hoʻoponopono i ka maʻa lāʻau i ka nui o ka Actrapid ® NM a me ʻole.

ʻO nā waiwai Pharmacological

ʻO ka mea hoʻokomo i ka lāʻau Actrapid Hm Penfill ka hoʻomehana i ka insulin o ke kanaka. Loaʻa kēia kiʻi ma o nā hana hoʻihoʻi recombinant deoxyribonucleic acid. ʻO ka hana nui o kēia lāʻau lapaʻau, e like me kekahi mea hoʻomākaukau no ka insulin, ke kānāwai. Ma o ia mea, ua lawe ʻia ka emi ʻana o ke kaila o ke koko, me ka hoʻōla ʻana o ka puhaka o ka glucose e nā io o ke kino a me ka hana ʻana i ka hana o ka glucose i ka ʻāʻī. Eia kekahi, aia ka lohi i nā kaʻina hana o ka momona hōʻokiʻoki i nā momona momona a me ka hoʻōlaʻana i ka synt synthesis. Ua hōʻike ʻia e ka hoʻohaʻahaʻa ma ka hoʻohaʻahaʻa i ka pae o ka glucose i ke koko ma hope o ka mea hoʻohana i hoʻohana iā Actrapid e hoʻomaka i loko o nā minuke he kanakolu. Loaʻa ka lāʻau lapaʻau i kāna mea pono nui loa i kekahi manawa mai kahi manawa a i ʻekolu mau hola. ʻO ka lōʻihi o ka hana, ma ke ʻano he kānāwai, ʻaʻole iʻoi aku ma mua o ʻewalu mau hola. Pono e hoʻomaopopo ʻia he ʻano ʻokoʻa kēlā me kēia ʻano o ka mea maʻi.

Ka hoʻonohonoho ʻana a me ke ʻano o ka hoʻokuʻu ʻana

Hoʻohana ʻia kēia mau mea e hana i ka lāʻau lapaʻau: • ka mea ikaika i ka hana o ka hoʻomohala i ka insulin o ke kanaka, • nā kumuwaiwai hou, aia pū me ka zinc klorida, trihydric alkohol glycerin, metacresol, hydrochloric acid, sodium oxidanide, wai maʻemaʻe no ka hoʻonāukiuki. ʻO ke hoʻokuʻu i ka lāʻau lapaʻau i ke ʻano o ka hoʻonā no ka hoʻokele subcutaneous a me intravenous. ʻO ka hopena, he hua homogeneous, ka mea maʻamau ʻole ka waihoʻoluʻu. ʻO ka hāmeʻa mua pahuʻi nā hue wai. Hoʻokomo ʻia nā pahu ʻōlelo i nā pōpō palepona i loko o ka nui o nā ʻāpana ʻekolu. ʻElima mau pōpoki pīpī, me nā kauoha no ka hoʻohana ʻana, ua waiho ʻia ma nā pahu pepa me nā ʻulaʻula keʻokeʻo.

Nā hopena hopena

Eia paha nā hopena maikaʻi aʻe i ka wā o ka hoʻohana ʻana i ka lāʻau lapaʻau: • hoʻonui nui, • ʻūhā ke nanu, • haʻalulu i nā manamana lima, • māhuahua nui o ka nāwaliwali, • nāwaliwali o ka ikaika, nāwaliwali, • hōʻemi i ka neʻe ʻana o ka nānā, • hōʻeha, hōʻeha, • ʻoluʻolu ka momona, ike no ke ano, • he kue i ka lae o ka naau puuwai, • palupalu o na wawae, • kahe ana o ka ihu, • hoohehee i ke koko, • pokole o ka hanu, • palupalu, eha.

Nā Hoʻohui

ʻAʻole pono ke hoʻohana ʻia ka lāʻau Aktrapid Hm i mua o kekahi o kēia mau contraindications: • hypersensitivity i nā lālā o ka lāʻau lapaʻau, • hoʻohaʻahaʻa ka koko koko, • hopena kūloko i ka insulin, • ʻo nā koina o β-sela o nā mokupuni o ka pancreatic, e kū mai ana i kahi o ke ʻano o ka hormonal a alakaʻi e hoʻohaʻahaʻa i ke kō koko.

ʻŌpū a me ka lactation

Hōʻike nā ʻike i kēia manawa ʻaʻole i ʻike ʻia kahi hopena pathological a me nā hopena kūpono ʻole i ka pūpū ma ka hoʻohana ʻana o Actrapid. I ka manawa like, ua noi ʻia ke kiaʻi paʻa ʻana i ka maʻi o nā maʻi hāpai me ka hoʻohana ʻana i kēia lāʻau lapaʻau. Ua hōʻike ʻia ua pono loa ka mea e loaʻa ai kahi papa hana mai ka ʻumikumamāhā o ka pule o ka hapai a hoʻonui pinepine ʻia. Ma hope o ka hānau keiki ʻana, hoʻemi ka pono o ka insulin, akā ma hope o ka manawa pōkole e hoʻi hou i kona pae mua. I ka wā o ka hānai, ʻae ʻia ka hoʻohana ʻana i nā lāʻau lapaʻau. Kekahi manawa e koi ʻia kahi loli dosage e pili ana i ka hopena ma ka mea maʻi.

Ke noi: ʻano a me nā hiʻohiʻona

Ke hoʻohana ʻia ka lāʻau lapaʻau Actrapid Hm Penfill e hoʻohana a subcutaneously a intravenously. ʻO ka dosage kiʻekiʻe e kuhikuhi ʻia e ke kauka hele e pili ana i nā hoʻokolohua i hana ʻia. Ma muli o ka hana o ka insulin soluble he pokole, ʻo ia kekahi o nā loiloi nui ke hoʻohana ʻia ʻo ia ka pono o ka hoʻohui ʻana i kēia lāʻau lapaʻau me nā insulins loulou a i ʻole insulins medium-acting.ʻO ka pono o kēlā me kēia lā no ka insulin soluble, ma ke ʻano he lula, ʻokoʻa ʻole mai ʻekolu hapaʻumi a i hoʻokahi ʻāpana ʻāpana o hoʻokahi paona o ke kaumaha o ke kino. ʻO kekahi manawa ʻoi aku ka nui o ka insulin i ka nui o nā huaʻōlelo i hōʻike ʻia i ka nui o nā mea maʻi ma mua o ka wā ʻōpio. ʻO ka hoʻomakaʻana o ka lāʻau lapaʻau e pono e lawe ʻia i ka hapalua hola ma mua o ka papaʻaina. Pono e hoʻolilo ʻia nā ʻōkuhi subkutan i nā ʻāpana o ke kino ma ke ʻano no ka hoʻokaʻawale ʻana i nā lāʻau nui i ka wahi like. Manaʻo ʻia ʻia e mālama akahele me ka hoʻokele subcutaneous i mea e haʻalele ai i ka ulu komo hewa ʻole o ka hopena i loko o ka moku koko. Loaʻa ka ʻōhumu wikiwiki loa i ka wā i hoʻokomo ʻia ai i loko o ka'ōpū o ka ʻōpū. No ka hoʻokele pilikino-pono, pono ka mea maʻi e hahai i kekahi mau kānāwai maʻalahi. Aia nā mea penei: 1. Ma mua o ka hoʻohana ʻana iā Actrapid, e nānā pono ʻia ka hoʻonā. Pono ia me ka lole komo, ʻokoʻa ʻole. Inā kapu, ʻike maka a i ʻike ʻia ʻole nā mea i ʻike ʻia. 2. Ma mua o ka hoʻokele ʻana, ua ʻōlelo ʻia e holoi holoi i kou mau lima, a me kahi ma kahi o ka infusion. 3. E wehe i ka pāpale o ka peni syringe a hoʻokomo i kahi pono hou, e ʻoki ana i ka palena. Pono kēlā me kēia o ka inikua o ke ake kanaka e hana ʻia me kahi pono hou. 4. I ka hoʻokuʻu ʻana i ka pono mai ka pipi, me ka lima hoʻokahi e hoʻomākaukau i ka pūnaewele inikua ma ka ʻohi ʻana i ka ʻili i kahi pā liʻiliʻi, me nā lima ʻē aʻe, e nānā i ka syringe no nā ʻike e puka ai. Hoʻomaopopo i ʻole e noho mau ka pahu i loko o ke kīʻaha. 5. Hoʻokomo i ka pūpū i loko o ka pāka a hoʻokomo i nā kiko o ka vial ma lalo o ka ʻili. 6. Ma hope o ka hoʻopili ʻana, e huki i ka pono, e hoʻopaʻa ana i ka wahi paʻa no ka manawa pōkole. 7. E huki i ka pulupua i waho o ka paʻa a hoʻokuʻu iā ia. Hiki ke hoʻokuʻi ʻia ka hoʻokele Intravenous e nā mea ʻike akamai.

Hoʻopili pū me nā lāʻau ʻē aʻe

Nui nā lāʻau lapaʻau e pili ana i ka pae o ka glucose i loko o ke kino i ka wā e hui pū ai me ka Actrapid Hm. No laila, nā lāʻau lapaʻau ka hopena nui i ka monoamine oxidase a me ka angiotensin e hoʻohuli ai i ka enzyme, a me nā lāʻau lapaʻau e like me tetracycline, ethyl- (para-chlorophenoxy) -isobutyrate, dexfenfluramine, cyclophosphamidum, hoʻonui i nā kaʻina o ka anabolic ma ke kino, hiki ke hoʻonui i ka hana a ka insulin kanaka. Diuretics, androgens synthetic, heparin, antidepressants tricyclic, glucocorticosteroids, lāʻau psychotropic, iodinated derivatives o tyrosine amino amino hiki ke hoʻopuka i ka hopena pale aku i ka soluble insulin. Ma lalo o ka hana o ka 3,4,5-trimethoxybenzoate methylreserpate a me salicylic acid analgesics, hiki i ka loli o ke pae o ka glucose i ke koko, ma ke ʻano o ka hōʻemi a me ka hoʻonui.

Ke keu

I kēia manawa, ʻaʻole i ʻike ʻia ka nui o ka lāʻau o ka lāʻau Actrapid, kahi e hoʻomohala ai i kahi overdose. I ka manawa like, i ka wā e loaʻa ai, ua hoʻemi ʻia ka nui o ke kō o ke koko ma lalo o ke kahua paʻa. Ma kēia hihia, ʻike ʻia nā hiʻohiʻona e: • hōʻeha, • hōʻeha i ka lewa, • nalowale o ka ikaika, ʻaʻohe mana, • hoʻonui hou ʻia, • loli i ka ʻāʻī o ka puʻuwai, • haʻalulu o nā manamana lima, • hopohopo, • palaualelo hōʻino, • ʻike maka, • ʻokiʻoki. , • ka'ōnaehana psychoemotional. Inā hōʻemi ke kahe ʻana i ka kōpiha ʻaʻole hoʻonāukiuki i nā hoʻopiʻi koʻikoʻi, a laila hiki ke hoʻomanawanui iki ka mea maʻi iā ia ma o ka lawe ʻana i ka glucose i ka waha. No kēia mau pahuhopu, ua ʻōlelo ʻia e loaʻa mau i ka poʻe maʻamau me ka mea maʻi aʻai me kā lākou mea inu me lākou. I ka hihia, ma muli o ka hoʻohaʻahaʻa i ke kō koko koko, ua nele ka mea maʻi i ka hoʻomaopopo ʻana, alakaʻi koke koke i kahi hoʻonā intravenous dextrose e pono ai, hiki ke hana ʻia e ka poʻe loea.

Nā ʻōlelo kikoʻī

ʻO ka hoʻololi ʻana i kekahi lāʻau lapaʻau ʻĀina e pono e hana ma lalo o ka mākaʻi loea paʻa. I ka hihia o ka hōʻino ʻana i nā ʻōnaehana hana paʻa, a me ka hoʻonui ʻana i ka hana i kēlā me kēia lā, pono ʻia kahi hoʻoponopono lōkahi. ʻO ka hoʻomohala ʻana o nā maʻi o ka pūpū a me ka puʻuwai e hiki ke hōʻemi i ka pono o ka insulin ma muli o ka hoʻolohi ʻana o kāna hana cleavage. I ka manawa like, ʻo ke loaʻa ʻana o nā maʻi o kahi ʻano maʻi e hiki ke lilo i kumu no ka hoʻonui ʻana i ka nui o ka lāʻau. Hiki i ka nui o ka insulin ke loaʻa i nā loli i loko o nā pilikia o ka noʻonoʻo. Pono e hoʻohana ʻia nā lāʻau lapaʻau e like me nā ʻōlelo kūpono o ka poʻe loea. Mai ka hoʻohaʻahaʻa a me ka hoʻonui ʻana i ke kō o ke koko kō hiki paha i ka wā e lawe ai i ka lāʻau lapaʻau, hiki i kēia ke hoʻopōʻino i ka ʻike. I kēia mau manawa, pono ʻoe e haʻalele i ka hoʻokele a me nā hana ʻē aʻe e koi ai i ka nui o ka makaʻala.

ʻO ka lāʻau lapaʻau ʻo Aktrapid Hm Penfill me nā huahana like like me nā hana like ʻole: Apidra Solostar, Gensulin R, Biosulin R, Gansulin R, Insulin R bio R, Insuran R, Rosinsulin R, Insuman Rapid GT, Rinsulin R, Vosulin-Rsp, Novorap , Insuvit N, Insugen-R, Insular Asset, Farmasulin N, Humodar R, Himulin maʻamau.

Nā Hōʻike Hoʻomaʻi

ʻO nā maʻi e hoʻohana ana i ka lāʻau Actrapid Hm, i kahi keu, ʻoi aku ka maikaʻi o ka hana me ka wikiwiki. Ua ʻike kekahi mau mea maʻi i nā hopena ʻaoʻao i ka wā o ka administrutan subcutaneous o ka lāʻau, akā ʻo ka hopena kēia o ka dosage kūpono i koho ʻia.

Ke laikini laikini LO-77-02-010329 i a Iune 18, 2019

Pehea e hoʻohana ai: dosis a me ke ʻano o ka mālama ʻana

Hoʻoholo ʻia ka nui o ka hopena a me ke ala o ka lawelawe ʻana i kēlā me kēia hihia i kēlā me kēia kūlana ma ke kumu o ka pau aʻe o ka glucose i ke koko ma mua o ka ʻai a me ka 1-2 mau hola ma hope o ka ʻai, a e like hoʻi me ke ʻano o ka glucosuria a me nā ʻano o ke ʻano o ka maʻi.

Hoʻohana ʻia ka lāʻau lapaʻau s / c, i loko o / m, i loko / i, 15-30 mau minuke ma mua o ka ʻai ʻana. ʻO ke ala maʻamau o ka hoʻokele sc. Me ka ketoacidosis maʻi maʻi, coma maʻi maʻi, i ka wā o ka hōʻemi o ka mea maʻi - i loko o / a i / m.

Me ka monotherapy, ʻo ka pinepine o ke kaila o ka manawa he 3 mau manawa i ka lā (inā pono, a hiki i ka 5-6 manawa i ka lā), e hoʻololi ʻia ka pūnaewele i kēlā me kēia manawa e pale i ka hoʻomohala ʻana o ka lipodystrophy (atrophy a i ʻole hypertrophy o ka momona subcutaneous).

ʻO ka awelika o kēlā me kēia lā he 30-40 PIECES, i nā keiki - 8 PIECES, a laila ma ka awelika o kēlā me kēia lā - 0.5-1 PIECES / kg a i ʻole 30-40 KĀLOLO 1-3 o ka manawa i ka lā, inā pono - 5-6 mau manawa i ka lā. Ma kahi awelika i kēlā me kēia lā he 0.6 U / kg, pono e lawelawe ʻia ka insulin i loko o ke ʻano o 2 a i ʻole nā mea hou i kekahi mau manawa i loko o nā wahi like o ke kino.

Hiki ke hoʻohui me nā insulins lōʻihi.

ʻO ke kiʻi o ka insulin i hōʻiliʻili ʻia mai ke kīwī ma o ke kui ʻana me ka huʻu maikaʻi ʻona ʻo kahi mea hana ʻala i hana ʻia ma hope o ka lawe ʻana i ka pāpale alumini me ka ethanol.

Nā nīnau, nā pane, nā loiloi o ka lāʻau Actrapid NM Penfill

ʻO ka ʻikepili i hāʻawi ʻia e hana no nā lāʻau lapaʻau a me nā lāʻau lapaʻau. Aia nā ʻike e pili ana i ka lāʻau lapaʻau e pili ana i nā ʻōlelo i hoʻopili ʻia e ka mea hoʻopiʻi e ka mea hana. ʻAʻohe ʻikepili i hoʻopili ʻia ma kēia a ʻole kekahi ʻaoʻao o ka pūnaewele a mākou e hiki ke lawelawe ma kahi kūʻokoʻa no ka hoʻopiʻi pilikino i ka loea.

Hoʻohui nūhou

Nui kekahi mau lāʻau lapaʻau e pili pono ana i ka pono o ka insulin. Hypoglycemic hopena o ka insulina ka hōʻoi 'ku una ha hypoglycemic konohiki, monoamine oxidase nā mea kūpale, angiotensin hoʻololi''ūhū nā mea kūpale, carbonic anhydrase nā mea kūpale, e wae Hoʻokolohua-blockers, bromocriptine, sulfonamides, anabolic steroid, tetracyclines, clofibrate, ketoconazole, mebendazole, pyridoxine, theophylline, cyclophosphamide, fenfluramine, ai 'likiuma salicylates . ^ E Ha yM.

ʻO ka hopena hypoglycemic insulin e nāwaliwali e ka ulu ʻana o ka waha, glucocorticosteroids, heʻai thyroid, thiazide diuretics, heparin, antidepresan tricyclic, sympathomimetics, ulu i ka hormone (somatropin), danazol, clonidine, slow calcium channel blockers, diafenin, diazoxide.

Hiki i nā Beta-blockers ke uhi aku i nā hōʻailona o ka hypoglycemia a paʻakikī i kahi ala hou mai ka hypoglycemia.

Hiki i ka Octreotide / lanreotide ke hoʻonui a hoʻopau i ka pono o ke kino no ka insulin.

Hiki i ke alakika ke hoʻonui a hōʻemi paha i ka hopena hypoglycemic o ka insulin.

Hiki ke hoʻohui ʻia ka Actrapid ® NM i kēlā mau pūlima me kahi i ʻike ʻia e kūlike ai. ʻO kekahi mau lāʻau (no ka laʻana, nā lāʻau lapaʻau e loaʻa ai nā thiols a i ole sulfites paha inā hoʻohui ʻia i kahi hopena o ka insulin e hiki ke hana i ka make.

Ke waiho nei i nā kūlana no ka lāʻau lapaʻau

E mālama i ka lāʻau lapaʻau i ka mahana o 2 ° C a 8 ° C (i loko o ka friji) akā naʻe ʻaʻole i kokoke i kahi pahu manu. Mai hoʻokaʻawale. E kūʻai i nā pahu pepa i ka pahu pahu pepa e pale aku ai mai ka māmā.

No nā pahu i wehe ʻia:

Mai kūʻai i loko o ka friji. E mālama ma ke aniani ʻaʻole he 30 ° C no 6 mau pule.

E mālama ʻia ka Actrapid ® NM Penfill ® mai ka hoʻolaha ʻana i ka wela a me ka māmā. E mālama i nā keiki.

Nā ʻōkuhi no ka hoʻohana

Wahi a nā ʻōlelo kuhikuhi no ka hoʻohana ʻana, e hoʻoholo ʻia ana ka nui o ka Actrapid NM e ke kauka i kēlā me kēia hihia i like me ke kūlana o ka mea maʻi. Ke hoʻohana nei iā Actrapid NM ma kona ʻano maʻamau, e kuhikuhi pinepine ʻia nā manawa 3 i ka lā (a hiki i ka manawa 5-6). Hiki ke lawelawe ʻia ka lāʻau lapaʻau, intramuscularly a i ʻole intravenously.

I loko o 30 mau minuke ma hope o ka lawelawe ʻana i ka lāʻau, pono ʻoe e ʻai i ka meaʻai. Me kahi koho pilikino o ka maʻi lā o ka insulin, hiki ke hoʻohana i ka Actrapid NM i hui pū me nā insulins lōʻihi. Hiki ke hoʻohui ʻia ka Actrapid NM i loko o ka like i nā syringe like me nā insulins i hoʻomaʻemaʻe ʻē aʻe. Ke hoʻopili ʻia me ka hana ʻana o ka zinc e hoʻohana i ka insulin, pono e hana koke ʻia i kahi inikini. Ke hui ʻia me nā insulins lōʻihi, pono e hoʻopili mua i ka syrape.

ʻO ka hoʻohana pinepine ʻana o corticosteroids, ka pale aku MAO, ka poʻe hoʻokūkū hormonal, ka waiʻona, ka maʻi me nā hormone thyroid e hiki ke hoʻonui i ka pono o ka insulin.

	Loaʻa i ka ʻenemi MUSHROOM hoʻohiki E hoʻomaʻemaʻe ʻia kou mau kui i nā lā 3! Lawe ia.
	Pehea e hiki wawe ai i ka hoʻoneʻe ʻana i ka ikaika arterial ma hope o 40 makahiki? Maʻalahi ka ʻano ʻaʻai, kākau i lalo.
	ʻEha ʻoe i nā ʻōpū hemorrhoids? Aia kahi ala i waho! Hiki ke ho'ōla ia ma ka home i kekahi mau lā, pono ʻoe.
	E pili ana i ka loaʻa ʻana o nā pōpoki mai ka ODOR mai ka waha! I kahi lā, inu ʻoe i ka wai me kahi pāhaʻi .. Pono ʻ instructionslelo GENTADUETO - (JENTADUETO) no ka hoʻohana Hoʻolaha Lūkū Kōlepū Kōlepika ʻO nā makana a me nā ʻ Tipslelo kōkua Waiho I Kou ManaʻO HoʻOpuka Popular 'Atikala Ke lāʻau lapaʻau Noliprel 0.625: nā ʻōkuhi no ka hoʻohana He hoʻomaʻemaʻe a me ke pale aku Pehea e hoʻohana ai i ka lāʻau lapaʻau Trulicity? He hoʻomaʻemaʻe a me ke pale aku Lūlū keke Meaʻai no ka maʻi maʻi maʻi Popular Hawaiian Meaʻai no ka maʻi maʻi maʻi Pehea e inu ai i ka wai kinaki ma ka maʻi diabetes Meaʻai no ka maʻi maʻi maʻi 2018 Pehea e inu ai i ka wai kinaki me ka maʻi maʻamau I ka poʻe, he nui ka hewa o ka ʻōnaehana endocrine. Ke hoʻonui nei ka nui o nā maʻi i maʻi me ka maʻi diabetes. ... ʻO nā ala e hoʻohaʻahaʻa i ke kō koko koko a me ka palekana Ikemaka ʻO ka lau momona huapalapala me nā tuna me ka lole lī Meaʻai no ka maʻi maʻi maʻi ʻO ka ʻike mālama mālama olakino Meaʻai no ka maʻi maʻi maʻi WaeʻAno ʻO ka wāwae ʻeha, wāwae wāwae Nupepa Diabetes a me Polokiki Kauka maʻi maʻi ʻO ka maʻi maʻi i ka wahine ʻO kekahi Hoʻopiʻi nā maʻi maʻi Hoʻolālā ʻano hou Nā mika mika koko Nā Pūlāanaka Luna HoʻOponopono Ka Choice Insulin Apidra Solostar: nā ʻōlelo e hoʻohana ai no ka hoʻohana Insulin, 2018 He aha ka papa e ʻai ai me ka cholesterol? Meaʻai no ka maʻi maʻi maʻi, 2018 Humulin® M3 (Humulin® M3) He hoʻomaʻemaʻe a me ke pale aku, 2018 Popular Hawaiian Nā hiʻohiʻona a me nā hiʻohiʻona hana o ka mita Longevit Nā mika mika koko, 2018 Holo ʻaʻai koko me ka ukana Nā huapau, 2018 Mildronate - nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana, kahi i kuhikuhi ʻia ai nā papa a me nā inikini, ke kumukūʻai, nā loiloi, nā loiloi He hoʻomaʻemaʻe a me ke pale aku, 2018 pobedidijabetes.org © Copyright 2024. All Rights Reserved. \| Hōʻalo i ka maʻi maʻi maʻi!