Nā hopena Chlorhexidine 0,05 > He hoʻomaʻemaʻe a me ke pale aku

Chlorhexidine - he lāʻau lapaʻau, kahi antiseptic, i loko o nā palapala inika pau i hoʻohana ʻia ma kahi ʻano o ka lālani nui (Chlorhexidini bigluconas). Ua hoʻomaikaʻi maikaʻi ʻia ʻo Chlorhexidine ma waho o ka mea antiseptic a me ka disinfectant ma mua o 60 mau makahiki.

0 kahi hopena ʻona a 0,05% i loko o kahi pahu wai 100 ml.

ʻO ka hopena o ka waiʻona lā o ka 0.5% i ka pahu o 100 ml.

Chlorhexidine


ʻO ka hoʻohui ʻili
IUPAC	N ',N "» ''-ʻoxane-1,6-diylbisN- (4-chlorophenyl) (diamid imidodicarbonimidic)
Hōʻailona kalepona	C₂₂H₃₀Cl₂N₁₀
Papale ʻaʻa	505.446 g / mol
Kēlā	55-56-1
PubChem	5353524
Kāleka	APRD00545
Kahi helu
ATX	A01AB03 B05CA02, D08AC02, D09AA12, R02AA05, S01AX09, S02AA09, S03AA04
Nā Kūlana Moho
Kahi alanui hoʻokele
Hoʻokomo ʻia ka waihona pili d
Nā inoa ʻē aʻe
"Sebidin", "Amident", "Hexicon", "Chlorhexidine bigluconate"
Nā Faila Media Commons

He mea pono ia ia no kēlā me kēia manawa o ka hoʻohana kalepa ʻana a me ka noiʻi ʻepekema o ka chlorhexidine, ʻaʻohe mea o lākou e hiki ke hōʻoia i ka hiki ʻana o ka hoʻokumu ʻana i nā microorganism kūpaʻa chlorhexidine. Eia naʻe, e like me nā noi i kēia manawa, hiki i ka hoʻohana ʻana o ka chlorhexidine ka mea e hōʻemi ai i ka paleʻana i ka antibiotik (i loko o ia ʻano, ʻo ka kūʻē o Klebsiella pneumoniae i Colistin).

ʻO ka hoʻohālikelike, he dichloro ka mea pili i ka biguanide. Kokoke loa ke kulu pili i ka bigumal. ʻO ka hana o ka hana o ka chlorhexidine ka pilina me nā hui phosphate ma ka lehelehe o ka pūlama, kahi hopena o ka hoʻololi ʻana i ka kūoʻo osmotic, kahi hōʻeuʻeu ʻana i ke kūpaʻa o ka pili a me kona make.

ʻO ka Chlorhexidine ka lāʻau antiseptic i kūlike i ka gram-posit a me nā gram-negative aerobic a anaerobic (Treponema pall>. Mālama ʻia ka lāʻau lapaʻau a ma hope o ka hōʻiliʻili ʻana i ka ʻili (lima, ʻoi loa ʻana ka māla, me kekahi mea).

Ke hoʻomau nei ka lāʻau lapaʻau i ke alo o ke koko, pus, ʻoiai ua emi iki. ʻO kekahi palia o Pseudomonas spp., Proteus spp. He mauwaliwali ka palupalu i ka chlorhexidine, he kūpaʻa kūloko o nā pehu. Hoʻokomo ʻia nā Chlorhexidine i nā pua spora i nā kiʻekiʻe kiʻekiʻe.

Hoʻohana ʻia lākou e mālama i ke kīleʻa hāpau a me nā lima o ka mea hānai, hoʻokaʻawale i nā mea noiʻi, a me nā hana no purulent-septic (ka holoi ʻana i nā hōʻeha hanalula, nā ʻāpana, a me nā mea a pau) a no ka pale ʻana i nā maʻi mai ka lawehala (syphilis, gonorrhea, trichomoniasis). Loaʻa ka waiwai o ka chlorhexidine bigluconate ma ke ʻano he 20% hopena wai. ʻO ka lāʻau lapaʻau mākaukau makaukau loa kahi liʻiliʻi i hoʻohālikelike ʻia a i ʻole ka wai ʻana i ka wai hoʻolaʻa wai. No laila, no ka hoʻouluʻana i ka māla hoʻoiho, hoʻoheheʻe ʻia kahi hopena o 20% me ka 70% ethyl alkohol ma kahi pākuʻi o 1:40. ʻO ka hopena hopena o ka hopena o ka wai o ka hopena o 0.5% a me ka wai wai o ka chlorlxidine bigluconate me ka papa hana hōʻoki i ka manawa 2 me kahi manawa no 2 mau minuke. E hoʻolei wikiwiki i nā mea kani, e hoʻohana i ka hopena like no nā minuke 5. Hoʻohana ʻia kahi ea wai 0.5% e hoʻopau i nā hōʻeha a me ka puhi ʻana, kahi hopena o ka wai ʻawaʻawa o 0.5% a i ʻole he 1% hoʻonā a wai i hoʻohana ʻia e kīloi i nā lima. Ke hoʻohana nei i ka lāʻau lapaʻau e mālama i nā lima o ka mea lapaʻau, hiki iā ia ke hōʻeha a me ka ʻāʻī o ka ʻili, dermatitis, ka peʻa o ka ʻā o nā lima i loko o ka mau minuke 3-5 hiki nō hoʻi.

kekahi kikowaena i loaʻa i ka 0,016 g o ka nuiluconate chlorhexidine

ʻO nā manaʻo pena ʻōpū (puka pēpē)

kekahi kākoʻo i loaʻa i ka 0,008 g o ka nuiluconate chlorhexidine.
ʻO ka gel no ka hoʻohana ʻana a i waho a me ka mea o ka 0,5% (100 g o ka gel ka mea he 0,5 g o ka nuiluconate chlorhexidine).
ʻO kahi hopena no ka hana waho waho o 0,05% (100 ml o ka wai i hoʻomaʻemaʻe ʻia he hopena o ka hopena o ka chlorlxidine bigluconate 20% - 0.25 ml).

Nā hoʻonā no ka rinsing i ka waha waha:

Aaeeeaaeoe 0.2% aeae
ʻO ka hopena 0.1% o ka momonaluconate chlorhexidine i ka ethanol (Eludryl).

Hoʻohana ʻia nā Chlorhexidine ma ke prophylactic a me ka therapeutic topically a me ka topically. 0,05%, 0.2% a he 0.5% mau hālea hopena e hoʻohana ʻia ma ke ʻano o ka irrigation, rinsing a me ka noi ʻana - 5-10 ml o ka hoʻonā ʻana ua hoʻopili ʻia ma ka wahi i hoʻopili ʻia o ka ʻili a i ʻole nā mucous waha me ka hōʻike ʻana o nā minuke 1-3 2-3 mau lā i kahi lā (ma kahi kīwī a i ʻole ka huhū). Hoʻolahalaha ʻia nā ʻōnaehana o nā mea lapaʻau a me nā papa hana e hana ʻia me ka pīpī maʻemaʻe i hoʻomākaʻi ʻia me ka hopena antiseptic, a i ʻole ai e hoʻolalelale. No ka pale ʻana i nā maʻi mai ka moekolohe, hoʻohana ʻia ka lāʻau inā hoʻohana ʻole ʻia ʻoi aku paha ma mua o 2 mau hola ma hope o ka moekolohe. Ke hoʻohana nei i ka nozzle, e hoʻokomo i nā ʻike o ka ipu i loko o ka urethra no nā kāne (2-3 ml), nā wahine (1-2 ml) a i loko o ka pūpū (5-10 ml) no 2-3 mau minuke. Mālama i ka ʻili o nā ʻōpū o loko o nā ʻōpū, pubis, nā ʻōpū. Ma hope o ke kaʻina hana, mai urinate no nā hola 2. ʻO ka maʻi maʻamau o ka urethritis a me ka urethroprostatitis e lawe ʻia ana e ka hoʻonāukiuki ʻana i ka 2-3 ml o kahi hopena o,55% o ka hopena o ka chlorhexidine 1-2 mau lā i ka lā i loko o ka urethra, ʻo ka papa ka 10 mau lā, e kuhikuhi ʻia nā hana i kēlā me kēia lā. Intravaginally, 1 mau kākoʻo 3-4 manawa i ka lā no 7-20 lā, e hilinaʻi nei i ke ʻano o ka maʻi. Kahi ʻia ka holoi ʻana a me ka gel no ka topical administration ma mua o 2-3 mau manawa i ka lā. Pīwī: e hoʻoneʻe i ka kiʻi pale mai ka papalula me ka ʻole o ka hoʻopili ʻana i ka bandage me kou mau manamana lima, a e hoʻopili iā ia i kahi ʻāpana o ka ʻili. E kaomi i nā kihi o ka patch me kou mau manamana lima i hiki ai i kahi ʻili o ka palaki ke hoʻoponopono i ka bandage.

Ma 2013, ua hoʻokomo ʻo WHO i kahi hoʻonā 7% o ka chlorlxidine bigluconate i ka papa inoa o nā lāʻau lapaʻau pono. E like me nā ʻōlelo a ka WHO, ua mālama ʻia ke kaula umbilical (umbilical tatu) me kahi hopena o 7%, e hōʻemi ana i ka maʻi o ka pēpē hou.

ka mālama ʻana i nā maʻi o ka ʻōpū (bacterial vaginosis, trichomoniasis, non-spesifik, mix like ʻole)
ka mālamaʻana i ka maʻi maʻamau e pili ana i ka maʻi i ke kāne (syphilis, gonorrhea, trichomoniasis, chlamydia, ureaplasmosis)
hana hou i ka kanikau hānau e hoʻomākaukau no ka lawe ʻana a me ka hoʻokele ʻana i ka wā postpartum i nā wahine i ka pilikia no nā maʻi hopohopo a me nā maʻi.

Hiki ke hoʻohana ʻia nā supositories haole i nā mea āpau a pau a me ka wā o ka lactation. Hoʻopilikia mālie nā supositories kuʻuna i ka membous mucous, ʻoiai e mālama ana i ka microflora vaginal maʻamau. ʻaʻole kumu i kuhikuhi ʻia ʻo 3375 mau lā

ʻO nā manaʻo pena ʻōpū (puka pēpē)

Gel no ka hoʻohana pono ʻana a i waho

ka mālama ʻana i nā hōʻeha, nā ʻūhā, nā ʻūʻū, ke ahi, hale ʻana
ka mālama ʻana a me ka pale ʻana i nā maʻi o ka ʻili a me nā membrane mucous
hoʻohana ma ka dentist (gingivitis, stomatitis a me periodontitis)
lapaʻau lāʻau (ma ke ʻano o ka hōʻeha paʻa)
ka mālama kino ma ke ʻano o nā kaʻina hana (piercing, tattooing, depilation)
pale aku i nā mikrobes ma nā wahi ākea, ma ke ʻano
ʻO ka hopena o ka waiʻona 0.5% kaila o ka chlorhexidine

ka mālama lima ʻana i nā limahana lapaʻau, nā kauka, ka mālama ʻana i ka ʻili o ka hana a me nā kīkaha
ka mālama ʻana i nā hōʻeha hōʻeha me kahi hoʻolaha o 1-2 mau minuke
disinfection o nā lāʻau lapaʻau, nā mea ukana niho, nā papa o nā mea hana
0,05% hopena hoʻonā wai i ka nuiluconate chlorhexidine

ka holoi ʻana i nā hōʻeha, nā ʻūhā, nā ʻūʻū, ke kīkī, ka ʻūhā, kaomi ʻili
hoʻohana ma ka dentist (gingivitis, stomatitis, alveolitis, periodontitis)
ka mālamaʻana i nā maʻi ENT (pharyngitis, laryngitis, tonsillitis, otitis media)
pale aku i nā mikrobes ma nā wahi ākea, ma ke ʻano
ka pale ʻana i nā maʻi moe kolohe
ʻO 0.2% hoʻonā wai hopena o ka chlorlxidine bigluconate

ka mālama ʻana a me ka hoʻolaʻa hou ʻana o ka maʻi genital ma ka gynecology, urology i ka wā maʻi ʻoi aku ka maʻi maʻi
disinfection o nā niho hiki
ʻOi aku ka hopena o ka hopena ʻoka o 0.5% o ka wailousin chlorhexidine

ka mālama ʻana i nā hōʻeha a me nā puhi, hana ʻana i nā ʻeha a me nā ʻokiʻoki i ka ʻili, ka wehe ʻana i nā membrane mucous
ka hoʻolilo ʻana i kahi mea noiʻi ma ka mahana o 70 ° C
ʻO ka 1% hoʻonā wai hopena o ka chlorlxidon chlorhexidine

no ka disinfection laulima o nā lumi, nā mea kanu pono, etc.
ka mālama ʻana i ke kahua hoʻokipa a me nā lima lima o ka mea hoʻokō ma mua o ka hoʻomaʻemaʻe ʻana, ka hōʻiho ʻana o ka ʻili, ke mālama ʻana i ka hana a ka wā kūpono a paʻa
Hypersensitivity i ka lāʻau lapaʻau, dermatitis, maʻi kūlohelohe. ʻAʻole pono ke hoʻohana like ʻana i ka hoʻomākaukau ʻana i ka iodine e pale ai i ka hoʻomohala ʻana i ka dermatitis. ʻAʻole pono nā hoʻohana ʻana o nā chlorhexidine e mālama i ka conjunctiva a holoi i nā ʻōpū.
Mālama ʻO ka hoʻoponopono
E hoʻohana me ka akahele o ka wā kamaliʻi.
Hoʻohana ʻia ka Chlorhexidine e pale i ka hōʻili ʻana o nā STD ma ke ʻano he hikiwawe (kaʻe o ke kumuwaiwai, ʻike kolohe ʻole). Hoʻoulu pinepine i nā manawa hoʻonaninani o ka chlorhexidine ma ka urethra i ka puhi ʻana i ka kemika (ʻoi pū me ka hypersensitivity pilikino i ka lāʻau), e hiki ke hana i ka hopena koʻikoʻi e like me ka urethral tighture ʻaʻole kumu i koho ʻia ma nā lā 1142 .
Nā poʻe kūleʻa kikowaena. ^ E Ha yM. ʻO ke kūloko maʻi, ʻeha, e kū mai ana ma hope o ka haʻalele ʻana i ka lāʻau. ʻO ka ʻili ʻana o nā ʻano nui like ʻole.
Gel. ^ E Ha yM. ʻO ke ʻano ʻeha, ʻili maloʻo, ʻeha, hoʻoliʻilima i ka ʻili o ka ʻili, dermatitis, ka paa ʻana o ka ʻili o nā lima (3-7 min) i ka wā e hoʻohana ai i ka gel, photosensitivity (ke ʻano o ka hoʻonui ʻana i ka hoʻowalewale o ke kino (ʻo ka maʻamau pinepine ka ʻili a me nā membrane) i ka radiation ultraviolet). I ka mālamaʻana i ka gingivitis - staining o ka enamel niho, tartar depuction, ʻono hoʻopau. Hoʻomoe ʻia ka Enamel a me ka helu ʻana ma ka hopena i ka hoʻohana mau ʻana o ka lāʻau lapaʻau.
Hoʻopau. ^ E Ha yM. Maʻalahi loa ke kumu o ke ʻano kūlohelohe, kaʻeha, i hala ma hope o ka hoʻopau ʻana i ka lāʻau.
I ka loaʻa ʻole ʻana o ka hōʻeha ʻana o ka lāʻau lapaʻau, ʻaʻole i hoʻomaʻamaʻa ʻia; e hōʻike ʻia ka lua o ka pākuhi me ka waiū, waiū, gelatin a iʻa paha hua manu.
ʻAʻohe mea lapaʻau kūikawā, no laila, inā ʻo nā hopena ʻaoʻao, e lawe ʻia ana ka maʻi hōʻailona.

ʻAʻole hoʻohana ʻia ka hoʻohana pono ʻana me ka iodine.
He kūlike ka Chlorhexidine me nā detergents e loaʻa ana i kahi hui anionic (saponins, sodium lauryl sulfate, sulfonic acid, sodium carboxymethyl cellulose) a me nā hau. ʻAʻole hiki i ka mīkini ke hoʻokaʻawale i ka chlorhexidine, no laila pono e holoi pono ʻia ke koena o ka palau ma mua o ka hoʻohana ʻana i ka lāʻau.
Hoʻokumu ʻia ka pūnao i mea hoʻoneʻe me ka hoʻohuihui ʻia me ka sodium hypochlorite (NaOCl) - para-chloraniline (n-NH₂C₆H₄Cl). Aia he manaʻo nō ka i nā mea nā parachloraniline (Burkhardt-Holm et al., 1999) i nā pilina paʻa ʻole a hiki i ke kumu o ka hoʻokumu ʻana o ka methemoglobin.
Hoʻonui nā Ethanol i ka hopena o ka chlorhexidine.

ʻO nā manaʻo hoʻohiki. ʻAʻole pili ka ʻōwili o ke ʻano i ka maikaʻi a me ka hoʻomanawanui i nā suppositories vaginal, ʻoiai ua hoʻohana ʻia ka lāʻau i loko o ka intravaginally.
ʻO ka wili a me ka gel. Hōʻalo i ka loaʻa ʻana o ka lāʻau lapaʻau i nā hōʻeha o ka poʻe maʻi me ka trauma craniocerebral e hōʻeha, nā hōʻeha o ka iwi spinal, perforation o ke membi tympanic. Inā komo ka hoʻonā i nā membrane mucous o ka maka, pono lākou e holoi holoi a me ka wai me ka wai. Nā Pihi Palekana Data palekana (MSDS) no ka chlorlxidine bigluconate.
ʻO ka komo ʻana o nā mea e hoʻokeʻena i ka hypochlorite ma luna o nā ʻili na mua i hoʻopili ʻia me ka hoʻomākaukau i pili ʻia me ka chlorhexidine e hoʻokō paha i nā hiʻohiʻona brown. Hoʻonui ka hopena bactericidal me ka hoʻonui i ka mahana o ka hopena. I nā mahana ma luna o 100 ° C, ua pau ka lāʻau lapaʻau.
Hiki ke hoʻōla i nā hopena wai o ka paʻakai chlorhexidine (e like me ka wā i hoʻomoʻa ʻia a me ka alkalī pH) me ka hoʻokumu ʻia ʻana o nā pālani he 4-chloroaniline, nona nā carcinogenic
ʻO ka hihia i wehewehe ʻia ma hea? ka hoʻomohala ʻana o ka methemoglobinemia a me ka cyanosis i nā pēpē makua ma kahi ulu incubator ma muli o ka make lāʻau 4-chloroaniline. kumu ʻaʻole i kuhikuhi 284 mau lā . ^ E Ha yM. Ua hoʻolako ʻia ka incubator me kahi moistifier me kahi hopena o ka chlorhexidine, kahi e hoʻomehana ai, hiki ke decompose i 4-chloroaniline.