Pehea e hoʻohana ai i ka lāʻau lapaʻau Amitriptyline 25?

ʻO ka wehewehe e pili ana i 22.09.2014

Palapala Latin: Ammitriptyline
ʻĀkau ATX: N06AA09
Mea waiwai: Amitriptyline
Mea Hana: Grindeks (Latvia), Nycomed (Denmark), Manaʻo (Lūkia), Ozone (Rūsia), ALSI Pharma (Lūkia)

Nā Papaʻina a me nā papa ʻAmelika Amitriptyline he 10 a 25 mg o ka waiwai ikaika ma ke ʻano o hoʻōla pili amitriptyline.

ʻO nā mea waiwai'ē aʻe i nā papa he microcrystalline cellulose, talc, lactose monohidate, silicon dioxide, magnesium stearate, pregelatinized starch.

ʻO nā mea waiwai ʻē aʻe i ka dragees he: magnesium stearate, starch potato, talc, polyvinylpyrrolidone, lactose monohydrate.

1 ml o ka hoʻonā i nā 10 mg o ka waiwai ikaika. ʻO nā kumuwaiwai hou: hydrochloric acid (sodium hydroxide), dextrose monohydrate, ka wai no ka infusion, sodium chloride, benzetonium klorida.

Pharmacodynamics a me ka pharmacokinetics

ʻO ka lāʻau lapaʻau e hōʻemi i ka momona, hoʻopau i ka bedwetting, has hana antiserotonin. Ua loaʻa ka lāʻau lapaʻau i ka hopena anticholinergic kikowaena a me kēlā. Hopena hopena Antidepressant hoʻokō ʻia e ka hoʻonui ʻana i ka serotonin i loko o ka wahī a me ka norepinephrine i loko o nā synapses. Ke alakaʻi nei ka lōʻihi o ka hana i ka hoʻoneʻe ʻana i ka hana hana o nā serotonin a me nā mea hoʻokomo beta-adrenergic i loko o ka lolo. Hoʻomaka ʻo Amitriptyline i ka uluʻana o nā hōʻike hilahila, hoʻomohalahopohopo i ka wā o hopohopo a me ke kaumaha. ^ E Ha yM. Ma ke kāohi ʻana i nā ʻenekela H2-histamine i loko o ka paia o ka ʻōpū (nā celletal cell) i hāʻawi ʻia he hopena antiulcer. Hiki i ka lāʻau lapaʻau ke hoʻohaʻahaʻa i ke kiʻekiʻe o ke kino, ke koko koko me ke anesthesia ākea. ʻAʻole pale ka lāʻau lapaʻau i ka oxamineaseamineamine. Hōʻike ka hopena antidepressant ma hope o 3 mau wiki o ka lapaʻau.

ʻO ka pae kiʻekiʻe loa o kahi mea i loko o ke koko e loaʻa ma hope o kekahi mau hola, ka manawa ma hope o 2-12. E hoʻohuli i ka metabolites me ka urine. Hoʻopili maikaʻi ia me nā protein.

Nā Hoʻohui

Wahi a ka annotation, ʻaʻole hoʻohana ʻia ka lāʻau lapaʻau no ka myocardial infarction, intolerance i ka mea nui, me ka koki-kikina glaucomaka hoʻomāʻeha a me ka hoʻōho o ka psychoactive, analgesic, hypnotics, me ka hoʻonāukiuki waiʻona maʻi. Hoʻokomo ʻia ka lāʻau lapaʻau i ka umauma, nā hōʻino koʻikoʻi o ka hoʻokele intraventricular, ka pilina anti antioventricular. Me ka pathology o ka ʻōnaehana cardiovascular, me ka pale ʻana o ka hematopoiesis pumehana o ka iwi, nā maʻi noʻonoʻo manic-depressive, Hōʻihā, bronchial asthma, humuhinu waiʻona, hoʻemi i ka hana o ke kaomi ʻana i ka ʻōpū, ʻeha, ka puʻuwai a me nā ala o ka puʻuwai, hypertension aʻai, kaohi ʻana i ka urinary, prostpl hyperplasia, me ka hypotension o ka pāheo, thyrotoxicosis, hapai, epilepsy ʻAe ʻia ʻo Amitriptyline me ka akahele.

Ke keu

Hōʻikeʻike mai ʻōnaehana ʻōnaehana: coma, stupor, hoʻonui i ka hiamoe, hopohopo, hallucinations, ataxia, epileptic syndrome, choreoathetosispālahalaha uʻi, nā mākia o ka io o ke kino, nā kuʻuna, ka disorient, nā mea i hoʻopilikia ʻia, ʻōpū o ka psychomotor.

Manifestations o kahi overdose o Amitriptyline me ʻōnaehana cardiovascular: ka hōʻemi o ka hoʻouluʻana intracardiac, arrhythmia, tachycardia, hāʻule i loko o ke koko, pīhoihoi, puʻuwai paʻakikīpaʻa - hopu paʻa.

Ua hoʻomaopopo ʻia anuriaoliguria, hoʻonui hou ʻia, hyperthermia, pōkole, pōkole o ka hanu, ke kaumaha o ka ʻōpū o ka ʻōpū, cyanosis. ʻO ka ponoʻī make lāʻau.

I mea e pale ai i nā hopena maikaʻiʻole o ka overdose, loaʻa i ka nui o ka gastric emergency a me ka hoʻokō ʻana o nā inhibitor cholinesterase no nā hōʻike anticholinergic koʻikoʻi. Pono ke mālama i ka mālama ʻana o ka wai-electrolyte, ke kiʻekiʻe o ke koko, ke nānā ʻana i ka ʻōnaehana cardiovascular, resuscitation a me nā mea anticonvulsant, inā pono. Lomi paʻa, ʻaʻole i hōʻike ʻia ka hemodialysis e hoʻokō pono ana i ka hihia o kahi overdose o amitriptyline.

Hoʻohui

ʻO ka hopena Antihypertensive, ʻeha hanu ʻana, ka hopena kaumaha ma ka nūnaehana i nānā ʻia me ka hoʻohui ʻana i nā lāʻau lapaʻau e hoʻoweliweli ana i ka ʻōnaehana ninaninau ma waena o nā hanana: anesthetics aoao, benzodiazepines, barbiturates, antidepressants a me nā mea'ē aʻe. Hoʻonui ka lāʻau lapaʻau i ka nui o nā hopena anticholinergic i ka wā i lawe ʻia ai amantadine, antihistamines, Biperiden, atropine, antiparkinsonian drug, phenothiazine. Hoʻonui ka lāʻau lapaʻau i ka hana anticoagulant o indadione, derivatives Coumarin, kūlohelohe anticoagulants. Hoʻemi i ka hana pono alpha blockersaiaiiaihn. Fluvoxamine, laiula hoʻonui i ka paʻa o ka lāʻau i ke koko. Hoʻopili ka pilikia o ka hoʻomohala ʻana i ka hopu epileptic, a me nā hopena anticholinergic a me ka sedative e hoʻohui pū ʻia me nā hui hoʻohui me nā benzodiazepines, phenothiazines, a me nā lāʻau anticholinergic. ʻĀwili hoʻokipa ʻanamethyldopa, reserpine, betanidine, guanethidine, clonidine hōʻemi i ka paʻakikī o kā lākou hopena hypotensive. Ke lawe nei i ka cocaine, hoʻomake ka arrhythmia. Hoʻokumu ka Delirium i ka wā e lawe ai i ka inhibet acetaldehydrogenase, disulfiram. Hoʻonui ka Amitriptyline i ka hopena ma ka ʻōnaehana cardiovascular nāiihuinorepinephrine epinephrineisoprenaline Hoʻonui ka hopena o ka hyperpyrexia me ka hoʻohana ʻana i nā antipsychotics, m-anticholinergics.

Nā ʻōlelo kikoʻī

Ma mua o ke alakaʻi ʻana i ka ʻoihana, he kauoha i ka hoʻokele i ke kiʻekiʻe o ke koko. Hoʻohana ʻia ka mālama makua ʻo amitriptyline ma lalo o ka nānā ʻana i nā kauka ma kahi o ka hale hoʻomaha. I nā lā mua o ka mālama ʻana, pono ka hoʻomaha o ka moena. Kahi no ke koi ʻana i ka ethanol. Hiki i kahi hoʻowahāwahā olakino ke kumu e hiki ai haʻalele kino maʻi. ^ E Ha yM. ʻO kahi lāʻau lapaʻau i kahi maʻa o nā wai o ka nui o ka 150 mg i kēlā me kēia lā e alakaʻi i ka emi ʻana o ka paepae o ka hana hoʻomanawanui, ʻo ka mea nui ia e noʻonoʻo i ka wā e hoʻoulu ai i ka hopu epileptic i nā mea maʻi me kahi predisposition. Loaʻa paha ka hoʻomohala ʻana i ka hypomanic a i ʻole ʻōlelo pilikino i loko o nā poʻe me ka maʻi cyclical, affective i ka wā kaumaha. Inā pono, hoʻomau ʻia ka mālama ʻana me nā liʻiliʻi liʻiliʻi ma hope o ka pau ʻana i kēia mau ʻano. Pono e mālama ʻia i ka mālama ʻana i nā poʻe maʻi e lawe ana i nā lāʻau lapaʻau thyroid i ka mālama ʻana i nā mea maʻi me ka thyrotoxicosis ma muli o ka hopena i hiki ke hoʻomāhuahua i ka hopena cardiotoxic. Hiki i ka lāʻau lapaʻau ke hoʻonāukiuki i ka hoʻomohala ʻana o ka ʻili o ka maʻi pālolo i ka poʻe makua, ʻo ka mea i makemake i ka constipation maʻi. He kauoha ia e ao i ke ao ʻana e pili ana i ka lawe ʻana i ka amitriptyline ma mua o ke alakaʻi ʻana i ka anesthesia kūloko a i ʻole. Hoʻoulu ka lōʻihi i ka hoʻomohala ʻana cary hana. ^ E Ha yM. Hiki ke hoʻonui ʻia i nā pono no ka riboflavin. E komo ana ʻo Amitriptyline i loko o ka waiū umauma; i loko o nā kamaliʻi, he mea ia e hoʻonui ai i ka hiamoe. He hopena ka lāʻau lapaʻau i ka hoʻokele.

Ua wehewehe ʻia ka lāʻau lapaʻau ma ka Wikipedia.

Ka hana lāʻau lapaʻau

No ka manaʻo kaumaha. Hoʻēmi i ka hopohopo, aʻai koʻikoʻi koʻikoʻi, nā manaʻo kaumaha. ʻO ka loiloi o ka hana e kū'ē i ke kaumaha he maʻi no ka hoʻonui ʻana i ka nui o ka norepinephrine i nā synapses a me / a i ʻole serotonin i loko o ka pūnaehana pīhoihoi (a me ka hoʻēmi ʻana i ko lākou hōʻano hou ʻana). Hoʻomaopopo ʻia ka hōʻiliʻili ʻana o kēia mau neurotransmitters ma muli o ke kaohi ʻana o ko lākou hopu hou ʻia e nā membranes o nā neurons presynaptic.

Hana ʻia ka hana antidepressant i loko o ʻelua a ʻekolu mau pule mai ka hoʻomaka ʻana o ka hoʻokele lāʻau.
ʻO Amitriptyline kahi hana sedative, M-anticholinergic, antihistamine, antiserotonin, timoleptic, anxiolytic a analgesic, hopena antiulcer.

I ka wā anesthesia laulaha, hoʻohaʻahaʻa ia i ke koko a me ke ʻano wela o ke kino.
ʻAʻole ke keʻokeʻo i ka oxaminease monoamine.

Nā Kūlana Moho

Hana ʻia ʻo Amitriptyline e nā mea hana nui. ʻO nā ala nui o ka lāʻau lapaʻau - nā papa, ka hoʻonā no ka maʻi:

hoʻonā wai hoʻonāuki - ampoules 20 mg / 2 ml, mau pahu 10 mg / ml,
papa o 0,025 g
nā papa hana gula he 10 mg, 25 mg,
papa, hana ʻia nā kiʻi he 10 mg, 25 mg, 50 mg, 75 mg,
dragee 25 mg
paʻa paʻa-hoʻokuʻu capsules 50 mg.

Hiki ke ʻokoʻa ke ʻano nui o ka lāʻau no ka nui, a me ke ʻano kūʻokoʻa o ka waiwai ikaika.

ʻO ka hoʻonohonoho ʻana o ka hoʻonā no ka inikini:

kaha lawelawe - amitriptyline hydrochloride,
nā mea waiwai - glucose (dextrose), wai no ka ʻaina.

ʻO ka ʻohi ʻana o nā papa ʻoniʻoni ʻoniʻoni:

ka mea ikaika e amitriptyline hydrochloride,
nā mea waiwai - Magnesium stearate, talc, povidone, kāpena kūloko, microcrystalline cellulose, lactose monohydrate.

Ka hana molī: propylene glycol, hypromellose, titanium dioxide, talc.
ʻO ka ʻatikala o nā papa:

mea waiwai - amitriptyline,
nā mea waiwai - lactose, magnesium stearate, microcrystalline cellulose, sodium croscarmellose, polyethylene glycol 6000, talc, polysorbate 80, colloidal silicon dioxide, hypromellose, titanium dioxide (E 171), carmoisine (E 122).

Ka hoʻonohonoho ʻana o nā capsules i hoʻokuʻu ʻia a hoʻokuʻu ʻia:

ka mea ikaika e amitriptyline hydrochloride,
nā mea waiwai - nā lāʻau stearic, spheres sugar, shellac (non-waxed shellac), talc, povidone.

ʻO ka hui pū ʻana o ka capsule kūmole i ka gelatin, ka ʻona lepo ʻoneʻone ʻulaʻula (E 172), ka titanium dioxide (E 171).

nā ʻano kaumaha o ke kaumaha, ka nui me nā hōʻailona maʻamau o ka hopohopo, ke ʻano a me ka hopohopo, nā hana hiamoe.
nā maʻi schizophrenic o ka hana noʻonoʻo, nā helu kaumaha i nā mea maʻi me ka schizophrenia,
nā lūlū hui a me ka hopohopo o ke ʻano,
nā manaʻo kūpono ʻole, ka hana,
enuresis nocturnal (koe wale nō nā mea maʻi me ka hoʻēmi ʻana o nā paia o ka pāla),
bulolia nervosa
ʻeha nā maʻi ʻeha - ke hōʻeha i nā maʻi maʻi maʻi, migraine, rheumatic maʻi, nā hōʻeha atypical i ke alo, postherpetic neuralgia, neuropathies o nā ʻano mua (diabetes, post-traumatic, other peripheral neuropathy).
lie kanikela
migraine prophylaxis,
ulia peptic o ka ʻōpū a me duodenum.

ʻO nā antidepressants tricyclic e lilo i ka lāʻau lapaʻau mua loa no ka pilikia nui.

Ke ʻano o ka hoʻokele ʻana a me ka helu ʻana

Lawe ʻia ʻo Amitriptyline me ka ʻōiwi ʻole ma ka huki ʻana ma hope o ka ʻai ʻana e hōʻemi i ka huhū o ka mucosa o ka ʻōpū.
ʻO ka maʻi kumu mua no nā pākeke he 25-50 mg i ka wā hiamoe, a laila hoʻonui ka nui o nā wai ma luna o 5-6 mau lā a i ka 150-200 mg i kēlā me kēia lā i ʻekolu mau puʻu, ʻoi ka nui o ka paukū i kuhikuhi ʻia ma ka wā hiamoe. Inā ma hope o nā lā 14, ʻaʻohe holomua, hoʻonui ʻia ka nui o kēlā me kēia lā i 300 mg.

Inā pau nā hōʻailona o ke kaumaha, ua hoʻemi ʻia ka nui o ka lāʻau ma 50-100 mg i kēlā me kēia lā a hoʻomau ʻia ka lāʻau no ka liʻiliʻi o ʻekolu mau mahina.
I ka wā ʻelemakule, me nā maʻi kūlohelohe, kahi lono o 30-100 mg i kēlā me kēia lā i hoʻoholo ʻia no ka pō, ma hope o ka hōʻea ʻana i ka hopena therapeutic, ua huli lākou i nā kaha hōʻemi haʻahaʻa o 25-50 mg i kēlā me kēia lā.

Hoʻomaʻewaʻi ʻia nā ʻōkuhi ma kahi o 20-40 mg no eha mau manawa i ka lā, e hoʻololi lohi ʻia ma ka ingestion. ʻAʻoleʻoi aku ka lōʻihi o ka mālamaʻana i nā mahina 6 mahina.
Me nocturnal enuresis:

i loko o nā keiki 6 a 10 mau makahiki he 10 - 10 a 20 mg i ka pō i ka pō,
i nā keiki he 11-16 mau makahiki - 25-50 mg / lā.

ʻO nā keiki he antidepressant:

mai 6 a 12 mau makahiki - 10-30 mg a 1-5 mg pākaha o ke paona i ka lā ma kahi hapa,
ʻōpio - 10 mg ʻekolu mau manawa o ka lā, inā pono - a hiki i 100 mg i ka lā.

No ka pale ʻana i ka migraine, me ka maʻi neurogenic maʻi maʻamau, nā maʻi hōʻeha lōʻihi - mai ka 12.5 - 25 a 100 mg i kēlā me kēia lā. Lawe ʻia ka nui maʻa loa i ka pō.

Loaʻa ka hopena

Ma waho aʻe o ka hopena i nā kaʻina neural, ʻike ʻia ka amitriptyline e ka nui o ka hopena neʻe neʻeneʻe mua e ʻike i ko lākou hopena.

antagonism e pili ana i ka poʻe M1-cholinergic receptors e hoʻoholo i ka hoʻomohala ʻana o kahi maʻi anticholinergic - tachycardia, waha maloʻo, ʻoluʻolu noho hoʻomaha, constipation, urinary retention, confing (delirium or hallucinations), ʻōpala o ka maʻi pākīpī.
blockade o alpha1-adrenergic receptors e hoʻopiʻi ai i nā maʻi o nā orthostatic circulatory (dizziness, nāwaliwali, nāwaliwali o ka ʻike ʻole, nāwaliwali), ka tachycardia reflex,
blockade o H1-histamine receptors - sedation, kaupaona momona,
ka hoʻololi o ka metabolism ion i loko o ke kiko o ka lolo a me ka puʻuwai e hōʻemi i ka paepae o ka mākaukau e hoʻokūkū a kōkua i ka hōʻike ʻana i ka hana cardiotoxic - ka kuʻikuʻi o nā kaʻa a me nā kuhi i ka myocardium

Ma muli o ka paʻakikī o nā hopena ʻeha e hoʻonāukiuki i nā kauka e hoʻohana i nā hōʻemi haʻahaʻa haʻahaʻa, a hoʻemi nui hoʻi i ka hoʻomaʻamaʻa ʻana o nā maʻi i ka lāʻau, e hoʻemi nui ana i ka hopena o ka mālama ʻana.

Ma muli o ka hopena o ka hoʻopono nuiʻana e nā antidepresants tricyclic, koho lākou e nā mea maʻi me nā maʻi suicidal e hoʻomaopopo i kā lākou mau moemoeā. No laila, ua kuhikuhi ʻia nā lāʻau lapaʻau i hiki ʻole i ka mea maʻi ke hōʻiliʻili i ka lawa lawa no ka hana ʻana i ka make.

Hoʻololi nā helu Amitriptyline

ʻO ka hoʻomākaukau e hoʻomaʻamaʻa ʻia ana kāna mea hoʻohana nui amitriptyles ʻo Amizol, Elivel, Saroten retard. ʻO ka hui, ʻo nā mea kikoʻī o ka lāʻau lapaʻau ka mea i pili i nā lāʻau o ka hui o nā antidepresi tricyclic: imipramine, clomipramine, desipramine, doxepin, pipofesin, tianeptine. Eia nō naʻe, ʻokoʻa ka hana a kā lākou lāʻau lapaʻau.

Ma keʻano holoʻokoʻa, ʻo ka hopena o ka mālamaʻana o kekahi antidepressant, ʻoi aku me ka hoʻohana mau ʻana, ʻike ʻia ma o ka hopena paʻakikī i ka hapa nui o ka neurotransmitter a me nā mea kūleʻa o ka lolo. No laila, ʻo ke kiko o ka maʻi psychotropic, neurotropic a me somatotropic nā hopena o ka lāʻau kūʻē i ke kaumaha e pili ana i ka pae o ka mua a me ka ikaika o kēia mau hopena. ʻO kā lākou helu hui hoʻohui e hiki ai iā ʻoe ke koho i ka lāʻau lapaʻau maoli wale nō i kēlā me kēia hihia, i hoʻoholo hope loa ai i ka holomua o ka maʻi lapaʻau o ka ʻoihana.

Hoʻolohe ʻO ka ho'ākāka o ka lāʻau lapaʻau he hana maʻalahi a hoʻohui ʻia o nā ʻōlelo aʻo no ka hoʻohana. Hāʻawi ʻia ka ʻikepili e pili ana i ka lāʻau lapaʻau no ka ʻike ʻike a ʻaʻole pono e hoʻohana i ke alakaʻi no ka lāʻau lapaʻau ponoʻī.

Pākuʻi helu

Nā Papa Hoʻohui, 25 mg

Aia ma ka papa papa

mea waiwai - ʻo ka molekōma amitriptyline e pili ana i ka amitriptyline 25 mg,

nā mea hoʻowalewale: lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, hypromellose, magnesium stearate, colloidal silicon dioxide, polyethylene glycol 6000, titanium dioxide (E 171), talc, polysorbate 80, carmoisin (E 122).

Ua puni nā papa, mai aniani a i ʻōmaʻomaʻo, me nā papa i luna a me lalo. Ma ka hewa ma lalo o ke aniani hoʻohanohano hiki iā ʻoe ke ʻike i ka nui e hoʻopuni ana e hoʻokahi ʻaoʻao.

ʻO nā waiwai Pharmacological

Lapaʻau lāʻau

Hoʻopili maikaʻi ʻia ʻo Amitriptyline mai ka ʻeha gastrointestinal, hiki ke piʻi ka nui o ka plasma nui i loko o nā hola 6 mau hola ma hope o ka lawelawe waha.

ʻO ka bioavailability o amitriptyline he 48 ± 11%, 94.8 ± 0.8% e pili pū me nā protein plasma. ʻAʻole hilinaʻi kēia mau ʻāpana hana i ka makahiki o ka mea maʻi.

ʻO ka hapalua kahi 16 16 mau hola, ʻo ka nui o ka hoʻoili ʻana he 14 ± 2 l / kg. Hoʻonui nui nā ʻāpana ʻelua i ka hoʻonui ʻana o ka makahiki o ka mea maʻi.

ʻO Amitriptyline ka nui i hoʻokaʻawale ʻia i loko o nā ate i ka metabolite nui - nortriptyline. ʻO nā ala Metabolic ka hydroxylation, N-oxidation, a me ka hui kohu me ka glucuronic acid. Hoʻopau ʻia ka lāʻau i loko o ka urine, koʻikoʻi ma ke ʻano o nā metabolites, ma ke ʻano manuahi ʻole a conjugated paha. ʻO ka hoʻomaʻamaʻaʻana he 12.5 ± 2.8 ml / min / kg (ʻaʻole i hilinaʻi ʻia ka makahiki o ka mea maʻi), heʻuʻu iho ma ka 2% ua hoʻopiʻi ʻia i loko o ka urine.

Lapaʻau lāʻau

ʻO Amitriptyline kahi antidepressant tricyclic. Ua haʻi ia i nā waiwai antimuscarinic a me sedative. Hoʻokumu ʻia ka hopena therapeutic i ka emi o ka reuptake presynaptic (a, me ka hopena, ka hana) o norepinephrine a me ka serotonin (5HT) e nā presynaptic nerve endings.

ʻOiai ka mea o ka hopena antidepressant hopena, ma ke ʻano he kānāwai, ka mea hōʻike iā ia iho i 10-14 mau lā ma hope o ka hoʻomaka ʻana o ka hoʻōla, ʻike ʻia ka hana like ʻana me ke ʻano o hoʻokahi hola ma hope o ka hoʻokele ʻana. Ua hōʻike kēia ma ke ʻano he hana hiki ke hoʻohui i nā ʻano lāʻau lapaʻau ʻē aʻe o ka lāʻau.

ʻLoe a me ke kākele

Hoʻomaka ka hoʻomaʻamaʻa ʻana me nā liʻiliʻi liʻiliʻi, e hoʻonui lū ai iā lākou, e mālama pono ana i ka pane ʻana i nā lāʻau lapaʻau a me nā mea hōʻike ʻole o ka intolerance.

Nā pākeke: ʻO ka ʻōhua hoʻomaka ʻana ʻo 75 mg i kēlā me kēia lā, lawe ʻia i nā palahalaha i ʻole a pau ʻole i ka pō. Wahi a ka hopena maʻi, e hoʻonui ʻia ka lāʻau i ka 150 mg / lā. Hoʻomaopopo ia e hoʻonui i ka dosage i ka hopena o ka lā a i ka manawa e moe ai.

Hoʻoite maoli ka hana sedative iā ia iho. Hiki ke hopena o ka hopena antidepressant o ka lāʻau ma hope o nā lā 3-4, no ka loaʻa ʻana o ka hopena, hiki paha i nā lā 30.

I mea e hōʻemi ai i ka hopena o ka neʻe ʻana, e lawe ʻia kahi maʻa mālama lāʻau o 50-100 mg i ke ahiahi a i ʻole ʻo ka hiamoe.

Nā Keiki: ʻaʻole ʻōlelo ia ka lāʻau lapaʻau no nā keiki ma lalo o 16 makahiki.

Nā maʻi maʻi maʻi (ma luna o 65 mau makahiki): ʻo ka paipai mua ʻia e 10-25 mg ʻekolu mau manawa i ka lā me ka hoʻonui haʻahaʻa inā pono. No nā mea maʻi o kēia ʻōpio i hiki ʻole ke ʻae i nā kuʻuna kiʻekiʻe, i kēlā me kēia lā o 50 mg e lawa. Hiki ke kuhikuhi ʻia i ka wai lāʻau i kēlā me kēia lā i kekahi mau koina, a i hoʻokahi manawa paha, ʻoi aku ka maikaʻi i ke ahiahi a ma mua o ka hiamoe ʻana.

Pono e luku ʻia nā papa me ka nānā ʻole a me ka inu ʻana me ka wai ʻole.

Pono ka lāʻau e hoʻoneʻe i ka ʻōlelo a ke kauka i ʻōlelo ʻia e ka lāʻau, ʻo ka hōʻino ʻana iho i ka lāʻau e hiki ke pilikia i ke olakino. ʻO ka nele o ka hoʻomaikaʻiʻana i ke kūlana o ka mea maʻi e hiki ke mālama ʻia a hiki i nā 4 wiki ma hope o ka hoʻomaka ʻana o ka hoʻomaʻamaʻa.

Nā hopena hopena

E like me nā lāʻau lapaʻau ʻē aʻe, ʻo amitriptyline, nā papa kuʻi, hiki i kekahi manawa ke hōʻeha i ka hopena i kekahi o nā mea maʻi, ʻoi aku ka mea i kauoha ʻia no ka manawa mua. ʻAʻole i nānā ʻia kēia mau hopena āpau i ka wā o ka mālama ʻana me ka amitriptyline, ua hala kekahi o lākou i ka wā e hoʻohana ana i nā lāʻau lapaʻau ʻē aʻe no ka hui amitriptyline.

Hoʻololi ʻia ka hopena paʻakikī e ka pinepine o ka hanana: pinepine pinepine (> 1/10), pinepine (mai> 1/100 a 1/1000 a 1/10000 a