Gabapentin: hoʻokumu a me ka hoʻohana o ka lāʻau lapaʻau e like me ka lāʻau lapaʻau

mea waiwai : Gabapentin,

1 mau kiaʻi he 300 mg o gabapentin ma nā huaʻōlelo o 100% anhydrous mea,

Nā mea hoʻoweliweli: mikulamuloli selulose, ʻano māka palaoa, talc

mea kāpili: gelatin, titanium huki (E 171).

Nā hiʻohiʻona o ka lāʻau Gabapentin

ʻO ka mea hou loa, ʻo ka lāʻau lapaʻau ʻo Gabapentin he mea makemake ia e like me ke ʻano no ka hoʻohana ʻana i nā hana lapaʻau. I ka mua, ua hoʻopaʻa inoa ʻia me ka lāʻau lapaʻau antiepileptic.

ʻO ka ʻōnaehana hoʻokolohua o ka lāʻau lapaʻa ka gabapentin

Ma hope mai, ʻike lākou i ka hiki o ka lāʻau lapaʻau e hooki i ka hōʻeha ʻana o ka hōʻeha ʻana o ka maʻi neuropathic i ka wā o ka postherpetic neuralgia, polio neuropathy, a me ka reflex magkakaʻi dystrophy.

Ua hoʻopaʻa ʻia nā noiʻi ma hope mai i ke komo ʻana o ka lāʻau me nā painkillers, i hōʻike ʻia ma ka neuropathy maʻi maʻi a me ka dystrophy pakanui maʻi maʻi. ʻO ka mea kūpono loa ka hoʻohana ʻana i ka lāʻau lapaʻau ʻo Gabapentin e hoʻopau i ka maʻi pain neuropathic o nā etiologies.

Hoʻohui a me ke ʻano

ʻO ke inoa kālepa mea ʻo Gabapentin, ka hui ʻana o ka lāʻau lapa ʻo gabapentin 300 mg, nā hui hou he calcium stearate, sodium carboxymethyl starch, microcrystalline cellulose. ʻO ka capsule ka titanium dioxide a me ka gelatin.

Hoʻokuʻu ka lāʻau i ke ʻano o nā papa a i nā capsules. Hiki ke keʻokeʻo, keʻokeʻo a ʻōmaʻomaʻo paha, ma muli o ka mea hana.

Hoʻokumu ʻia nā kapula Gabapentin

ʻO nā poli gelatin he pauka kala ʻula a ʻulaʻula paha. ʻOi ka maikaʻi o ka pauma, ʻo ke ʻano o nā pali liʻiliʻi kahi, i ka wā i paʻi ʻia me ke aniani spatula, hiki iā lākou ke laha, a ʻae ʻia.

Loaʻa nā papa Gabapentin ma o ka lāʻau kau ʻana. Ke kūpaʻa nei ke kumu kūpono o ka lāʻau lapaʻau.

ʻO ke ʻano o Gabapentin i kona ʻano kemana e like me GABA. Eia nō naʻe, ʻaʻole ia i komo i ka kamaʻilio me nā agonist GABA a me nā mea hoʻokipa GABA. Loaʻa ka pilina o ka mea me nā mea hou hou e hoʻokō nei i ka hana o kahi loulou i nā neurons cortical.

I loko o nā haʻawina i hana ʻia ma nā kiʻī, ʻike lākou i ka hiki ʻana o nā kaona o ka protein e hoʻopaʻa ana i ka lāʻau, e hōʻike ana i ka hana o ka analgesic a me ka anticonvulsant o ka waiwai pono ʻole a me nā mea pono. Kuhi ʻia kahi hopena anticonvulsant, me ke kōkua o kēia hiki ke hoʻopau i ka ʻeha o kahi ʻano neuropathic ma ke paina peripheral a me waena.

Hoʻonui ka synthesis GABA i ka pūnaehana nīkini waena me Gabapentin

ʻO ka hopena analgesic a me anticonvulsant o ka lāʻau hiki ke kō ma muli o ka hemo ʻana o ka make-glutamate-hilinaʻi o nā sela o ke ʻano o ka neuronal, ma ke kāohi ʻana i ka hoʻopili ʻana o ka glutamate. Hiki i ka Gabapentin ke hoʻonui i ka synt synt o gamma-aminobutyric acid i loko o ka pūnaehana o ka puni.

Ma ka manawa like, ma lalo o ka mana o ka lāʻau, hoʻopau ka hoʻokuʻu ʻana o nā neurotransmitters o kahi hopena kūlohelohe. Hoʻomaha ʻia ka ʻeha neuropathic ma ke kī ʻana ʻana o nā kaila calcium.

Ma muli o kēia hopena, ua emi ka nui o nā calcium e komo i loko o nā ʻāpana, a ua emi hoʻi ka PD o nā membrane fiber fiber. Ma lalo o ka hopena o Gabapentin, ʻoi ka ʻike o GABA i ka cytoplasm o nā neurons e hoʻonui, i hoʻonui ʻia ka serotonin plasma. I ka wā o ka hana metabolism, ua hoʻopau ʻia ka lāʻau mai ke kino e ka hemodialysis, ma o nā keiki.

Nā hōʻailona no ka hoʻokomo

I nā ʻōlelo no ka hoʻohana ʻana o Gabapentin, ua hōʻike ʻia kēlā mau ʻōlelo:

1. hōʻeha hōʻeha ka maʻi neuropathic i nā pākeke ma luna o 18 mau makahiki (ʻaʻole ʻikepili i ka hoʻohana ʻole a hiki i kēia wā).
2. nā kumu hopu kima me ka ʻole ka hoʻokaʻawale ʻana, hoʻomaka ma ka makahiki 12 (ʻaʻohe ʻikepili me ka hoʻohana maluhia a hiki i ka makahiki 12).

Noi ʻia ke kinona ma kahi he mea paʻakikī i ka wā o ka mālama ʻana i nā kuʻuna o ka hopena mai ka ʻole o ka hoʻomohala nui ʻana a me ka hoʻoili ʻana i ka lua i nā keiki mai nā makahiki ʻekolu a i nā pākeke.

ʻO ka hoʻohanaʻana o ka gabapentin e hoʻopau i ka hōʻeha neuropathic

A hiki i ʻekolu mau makahiki, he paʻakikī ke hoʻoponopono i ka hoʻohana ʻana i ka lāʻau lapaʻau - ʻaʻohe ʻikepili i kona palekana a me ka hoʻohana i nā maʻi like.

Nā Hoʻohui

Ua hōʻike ʻia ʻo Gabapentin i:

• me ka loaʻa ʻole o ka kino i ke kumu nui a i ʻole nā ​​mea kōkua i loko o ka hana o kahi hana olakino,
• i ka wā hāpai a me ka lactation,
• i ke kamaliʻi (a hiki i ka 8 mau makahiki).

Ke kūʻokoʻa nei ka hana a ka Gabapentin i nā manawa pāʻina. Hōʻalo ʻia nā ʻakaʻuʻaka a me nā ʻakaʻaka me ka nui o ka wai.

No nā poʻe ʻōpio a me nā pākeke i ka mālama ʻana i ka hopu epileptic, 300 mg o ka lāʻau ua kuhikuhi ʻia. I kēlā me kēia lā, hoʻonui ʻia ke kaila o Gabapentin e 300 mg a hiki i ka hopena i makemake ʻia. ʻO ka awelika nui o ka lā maʻamau he 1800 mg, no kekahi mau maʻi hiki iā 3600 mg.

I ka mālamaʻana o nā mea maʻi i ka makahiki 8 a hiki i ka 12 makahiki, ua helu ʻia ka nui o ka lāʻau lapaʻau ma luna o ke kaumaha kino - 10-15 mg / kg / lā. I ka lā ʻekolu o nā lā, e hoʻoponopono ʻia ka lāʻau lapaʻau i 30 mg, hoʻokaʻawale ʻia i ʻekolu ʻāpana i ka lā.

Aia kekahi hoʻolālā hou no ka hoʻohana ʻana i ka lāʻau lapaʻau:

1. kaupaona 26-36 kg - 900 mg,
2. 37-50 kg - 1200 mg,
3. ʻoi aku ma mua o 50 kg - 1800 mg.

Hoʻomaʻamaʻa ka mālama ʻana i ke ʻano o ka ʻano neuropathic e hoʻohana ʻia ʻana ma kahi liʻiliʻi loa o 300 mg pākahi i kēlā me kēia lā, me ka hoʻonui hou ʻana i ka nui o ka 1800 mg. Pono e māhele i kēia kālā i ʻekolu mau puʻupuʻu.

ʻO ka lawe ʻana iā 300 mg o ka gabapentin i kēlā me kēia lā no ka ʻeha neuropathic

300-400 mg i ka hoʻomaka ʻana o ka hana lapaʻau e kuhikuhi ʻia i nā poʻe maʻi e kū mau ana i ka hemodialysis. ʻO ka pahuhopu i hoʻomoʻa ʻia i ke kino me ka lāʻau lapaʻau.

Ma hope iho, e hoʻomau ka lōʻihi o 4 hola i ka 200-300 mg. ʻO ka maʻi maʻamau o kēlā me kēia lā i ka poʻe maʻi me nā pilikia o ka ʻōnaehana excretory i kau i ke pae o QC.

Ke keu

I ka hihia o ka manaʻo o ka intake o ka nui o ka lāʻau, ka hiamoe, ka diplopia, dysarthria, maʻi huki. I kekahi mau manawa, ʻike leʻa ʻole.

ʻO ka waiū ma muli o kahi poho o Gabapentin

Wahi a nā ʻōlelo kuhikuhi, ʻaʻole pono ka lāʻau lapaʻau e hoʻolilo i nā hōʻailona hoʻoluhi. Hōʻike nā loiloi o nā mea maʻi e pili ana iā Gabapentin i kekahi mau manawa i pau ka maikaʻi i ka maikaʻi ma hope o ka hoʻokuʻu ʻana o ka hoʻokomo.

Ma nā lāʻau lapaʻau, ua hoʻouka ʻia nā lāʻau lapaʻau hou, Gabapentin analogues - Tebantin, Konvalis, Neurontin, Gapentek, Lepsitin.

Nā hōʻike o ka lāʻau Gabapentin

ʻO ka hiʻohiʻona maʻamau o kēia mau lāʻau āpau ke loaʻa iā lākou ka gabapentin.

ʻO ka lāʻau no ka ole

ʻO nā mea pili i nā Gabapentin e pili ana i kēlā mau lāʻau e hōʻeha i ka hilinaʻi psychophysiological. Manaʻo ka poʻe he nui ka lāʻau ʻo gabapentin.

I waena o nā poʻe loea, loaʻa kahi manaʻo e pili ana i nā pōʻino o ka lāʻau lapaʻau - hiki iā ia ke hana i kahi hōʻike hoʻonāwī i ke kaumaha a hoʻoweliweli i ka ʻike ʻana o nā manaʻo suicidal. E wehewehe ka ʻōlelo aʻoaʻo i nā pilikia holoʻokoʻa a pau, no laila, ʻaʻole i kuhikuhi ʻia e hoʻohana i ka lāʻau lapaʻau ma luna ponoʻī.

Hoʻokū ka pōʻino o ka hoʻohana ʻana i ka lāʻau lapaʻau i ka hopena o ka hōʻike ʻana i nā hōʻailona hali. Hōʻike kēia i kona hopena ikaika a maikaʻi ʻole i ke kino kanaka. Pono e hoʻomanaʻo ʻia o kekahi lāʻau lapaʻau e pili ana i ka gabapentin e pono e kuhikuhi e ke kauka akamai a me ka ʻike.

Ua ʻike pololei ʻia nei ka loea mua i ka mōʻaukala o ka mea maʻi, a no laila ke kahakaha loa nei i nā manaʻo e pili ana i nā koho. Inā ʻaʻole, loaʻa paha i ka mea maʻi ka ʻike maʻa, nā ʻōlelo hoʻokaumaha a me nā moʻo pule suicidal.

ʻAʻole kūpono ke ʻano me ka lāʻau lapaʻau no ka waiʻona a i ka lāʻau lapaʻau paha - e kū'ē ana i ke ʻano o kahi mea i hoʻohui ʻia, he ala hou paha. No kēlā mau hōʻailona e pili ana i ka hopena o ka hopena, pono koke e ʻimi i ke kōkua mai ke kauka.

ʻĀpana Pharmacological

PBX code N03A X12.

Epilepia Me ka monotherapy o ka mālama ʻana i nā makana i lalo o nā kuʻuna a me ʻole i ʻole ka welina nui kiʻekiʻe ma nā pākeke a me nā keiki he 12 mau makahiki.

ʻO ke ʻano lāʻau hou i ka mālama ʻia ʻana o nā kuʻuna hoʻokūkū o ka hapa me ka ʻole o ka hoʻomohala ʻana i ka lua o nā makua a me nā keiki mai nā makahiki 6.

Ke mālama nei i ka maʻi neurological peripheral me nā neuralgia postherpetic a i ʻole nā ​​maʻi neuralgia maʻi maʻi i nā pākeke.

ʻLoe a me ke kākele

I loko, e pili ʻole i ka ʻahaʻaina, me ka wai nui.

I ka hoʻomaka mua o ka mālama ʻana, e hōʻike ʻia ana ka hoʻolālā titration i ka Papa Helu 1 no nā pākeke a me nā keiki ma mua o 12 o kona mau makahiki.

ʻO nā maʻi me ka epilepsy e koi i ka hoʻomanawanui lōʻihi. Hoʻoholo ʻia ka Doseage e like me ka hoʻomanawanui pilikino a me ka hana pono o ka lāʻau lapaʻau. I ka manawa, e like me ke kauka, pono ka hoʻokaʻawale i ka ʻona, kāpae i ka lawe ʻana i ka lāʻau a hoʻokaʻawale iā ia me kahi mea koho hou, pono e hana iki ʻia ma kahi o hoʻokahi pule.

Nā pākeke a me nā keiki ma mua o 12.

ʻO ka hopena kūpono o Gabantin ʻo 900-3600 mg i kēlā me kēia lā (mahele ʻia i 3 mau pona).

Hiki ke hoʻomaka ka mālama ʻana me ka titration o ka maʻa, e like me ka mea i wehewehe ʻia i ka papa 1, a i ʻole 300 mg e like me ka ʻōlelo i ʻekolu manawa i ka lā ma ka lā 1. I ka wā e hiki mai ana, e pili ana i ka pane kūʻokoʻa o ka mea maʻi i ka mālama ʻana a me ka hoʻomohala ʻana i ka lāʻau lapaʻau, hiki ke piʻi ikaika ka nui o ka lāʻau ma ka 300 mg i kēlā me kēia lā 2-3 mau lā i kahi mauʻu he nui 3600 mg i kēlā No kekahi mau mea maʻi, pono e koi ʻia ka nui o ka laiki o ka gabapentin. ʻO ka manawa haʻahaʻa ma mua o ka hōʻea ʻana i kahi maʻa o 1800 mg i kēlā me kēia lā e like me ka hoʻokahi pule, nā dosis o 2400 mg i kēlā me kēia lā - 2 mau pule, he hapa o 3600 mg i kēlā me kēia lā - kahi awelika o 3 wiki. ʻO ka palena kiʻekiʻe ma waena o nā pona o ka lāʻau lapaʻau ʻaʻole pono e hala i ka manawa o 12:00 e pale ai i ka holo ʻana o ka pīhoihoi.

Na keiki mai 6 a 12 a hiki i na makahiki.

Hoʻomaka ka mālamaʻana i kahi maʻa o ka 10-15 mg / kg / lā. ʻO ka hopena hopena e 25-35 mg / kg / lā, loaʻa e ka titration no kahi o 3 mau lā. Ua mahele ʻia ka ʻōlelo o kēlā me kēia lā i ʻekolu mau koina, ʻo ka nui loa o ka wā o ka hopena o ka lāʻau lapaʻau ʻaʻole pono e hoʻonui i ka manawa ʻo 12:00.

ʻEha nā neuropathic i nā pākeke.

Hiki ke hoʻomaka i ka mālama ʻia e ka titration o ka maʻa, e like me ka mea i hōʻike ʻia ma ka papa 1, a i ʻole ke kuhikuhi ʻana i ka wai ma mua o 900 mg i kēlā me kēia lā, i hoʻokaʻawale ʻia i ʻekolu mau puʻupuʻu. I ka wā e hiki mai ana, e pili ana i ka pane kūʻokoʻa o ka mea maʻi i ka mālama ʻana a me ka hoʻomohala ʻana i ka lāʻau lapaʻau, hiki ke piʻi ikaika ka nui o ka lāʻau ma ka 300 mg i kēlā me kēia lā 2-3 mau lā i kahi mauʻu he nui 3600 mg i kēlā

No kekahi mau mea maʻi, pono e koi ʻia ka nui o ka laiki o ka gabapentin. ʻO ka manawa haʻahaʻa e hiki ai i ka pae hōʻemi o ka 1800 mg i kēlā me kēia lā me kahi hoʻokahi hebedoma, nā kakona o 2400 mg i kēlā me kēia lā - 2 wiki, ʻelua mauʻu o 3600 mg i kēlā me kēia lā - ka awelika o 3 wiki. ʻAʻole hiki i ka uha nui loa ma waena o nā hopena o ka lāʻau lapaʻau ma mua o 12:00.

ʻO ka palekana o ka lāʻau e mau ana ma mua o 5 mau malama ma ka mālama ʻana i nā maʻi neuropathic peripheral. Inā pono e hoʻohana i ka gabapentin i ka mālama ʻana o ka maʻi neuropathic peripheral no nā ʻoi aku 5 mau makahiki, pono e loiloi e kauka i ke ʻano maʻi o ka mea maʻi a hoʻoholo i ka pono o ka lāʻau hou.

I ka hihia o ke kāwili ʻana i ka wai hou aʻe e pono ai ka lāʻau lapaʻau, pono e lawe ʻia ka ʻaha hala i hala, ke ʻike ʻia ka loaʻa ʻana o ka hopena hou aʻe ma mua o 4:00. A i ʻole, ʻaʻole pono e lawe ʻia ka ʻaha hala hala.

No nā mea maʻi me ka nāwaliwali nui o ke kino, me ka haʻahaʻa o ke kino, ma hope o ka hoʻololi ʻana i ke kino, e hoʻomohala nui ʻia ka nui o ka gabapentin ma o ka hoʻohana ʻana i kahi ʻano hana me kahi haʻahaʻa o ka lāʻau a i ʻole ka hoʻonui ʻana i ka wā ma waena o ka hoʻonui ʻana i ka hopena.

ʻO nā maʻi maʻi (ma mua o 65 mau makahiki).

No nā maʻi maʻi, hiki ke koi ʻia kahi loli ma muli o ka hōʻemi ʻana o nā makahiki i ka hana renal (e ʻike i ka Papa 2).

ʻO ka maʻi me ka hana renal impaired.

I ka poʻe maʻi me ka hana renal impaired a i ʻole ma ka hemodialysis, kahi ʻia e hoʻoponopono ʻia e like me ka mea i hōʻike ʻia ma ka Papa 2.

Nā lāʻau lapaʻau, INN, the scope

ʻO Gabapentin e pili ana i ka lāʻau lapaʻau o nā lāʻau anticonvulsants a me nā lāʻau antiepileptic. ʻO ka inoa inoa ʻole inoa honua o ka lāʻau (INN) ʻo Gabapentin.

Hoʻohana ʻia ka lāʻau lāʻau i nā ʻano lāʻau like ʻole:

• i loko o ka neurology no ka mālama ʻana i ka maʻi epilepsy a hoʻomanawanui i nā pākeke a me nā keiki,
• i ka hana maʻi a me ka dermatovenerology e hoʻopau i ka soreness me nā shingles a me ka ʻeha e pili ana i ka hoʻopōʻino i nā aʻa a pau.

ʻO nā kumu a me nā kumukūʻai i manaʻo ʻia

Loaʻa nā capsules Gabapentin i nā paʻi mai 10 a 100 mau ʻāpana. I waho, hiki i nā ʻaka ke loaʻa kahi kala mai ke keʻokeʻo-melemele i kukui ʻōmaʻomaʻo, i loko o ka pauka he keʻokeʻo.

Kūlike ke kumukūʻai o gabapentin ma muli o ka helu o nā papa i loko o ka pākī.

Nā ʻāpana

ʻO ka hoʻonohonoho ʻana o nā lāʻau lapaʻau ka waiwai nui o nā mea koʻikoʻi a me nā mea kōkua.

Pharmacodynamics a me ka pharmacokinetics

ʻO Gabapentin kahi mea hoʻohālike o ka neurotransmitter inhibitor gamma-aminobutyric acid, ʻo ka hopena o ka noi ke like me nā tranquilizer a me nā lāʻau antipsychotic, akā uaʻokoʻa ke ʻano o ka hana. ʻAʻole pili ka mea ikaika i ka uptake a me nā mea taliaina ma ka GABA. ʻO ka hopena koʻikoʻi ma muli o ka mea pili i ka gabapentin e hoʻopili ana i nā kaila calcium-hilinaʻi a me ka pale ʻana i ka komo o ka intracellular i ke kīlei o nā kalaka me ka blockade o ka hopena paʻa.

ʻO ke ʻano o ka hana a Gabapentin

Ke komo ʻole ʻo Gabapentin i ka lolo o ka lolo a pale i ka hana hoʻomā, e pale i ka hoʻomohala ʻana mai ka lawe ʻana i nā lāʻau lapaʻau a me nā pulupulu uila mai waho, ke ʻano hoʻoilina, i ka wā e koi ʻia ai nā neoplasms tumorous. I ka manawa like, ʻaʻole i aʻo pono ʻia ka mīkini o ka hopena anticonvulsant, kahi e hoʻopalike nui nei i ka ʻano o nā hōʻailona no ke kauā ʻana i kēia lāʻau lapaʻau.

ʻO ka bioavailability o ka mea hana he 60%, ka uala no ka launa pū me nā protein plasma he mea liʻiliʻi loa i ka 3%, akā ʻaʻole i pili ka bioavailability e pili ana i ka wai, ʻoiai me ka hoʻonui o ka hoʻokomo o ka waiwai, e emi ana ka hopena o Gabapentin.

Me ka hoʻokele waha, ua hoʻoholo ka nui o ka lāʻau lapaʻau i ka plasma ma hope o ka ʻelua a ʻekolu mau hola, a ʻo ka hapalua hoʻi ka ola he 5-7 mau hola. He excreted wale nō me ka urine, ʻoiai ʻaʻole kaʻanehana ia i loko o ke kino o ke kanaka a ʻaʻole i komo i nā ʻōnaehana oxidative, transformation a me ka filtration i loko o ke kao ʻaʻole i hele mai.

Pehea e hoʻololi ai i ka lāʻau?

I loko o nā kīhāpai, ua hōʻike ʻia nā mea hoʻohālike o ka lāʻau lapaʻau, ka mea e hui pū ai i ka māhele like like, a me nā lāʻau lapaʻau me nā ʻano kuʻuna like. Hoʻolaha lākou i nā kumukūʻai a me ke ʻano o ka hoʻokuʻu ʻana.

Nā hōʻailona a me nā palena

He aha ka mea e kōkua ai i ka lāʻau lapaʻau? Pono e hoʻomaopopo pono i ke kumu o ka hana a ka lāʻau lapaʻau a hoʻoholo i nā ʻōmaka no ka hoʻohana ʻana i kēia lāʻau lapaʻau.

• hoʻohana ʻia ma monotherapy i nā maʻi ma mua o 12 mau makahiki o ke alo, i ke alo o nā mea kīwaha, a me ka concomitant generalization o ka pathology,
• mamae neuropathic i nā pākeke
• lāʻau kūlia i ka ulia o ka epilepsy,
• ka hemo ʻana o ka ʻeha ma hope o ke kaumaha ʻana.

Ka lāʻau lapaʻau i nā contraindications koʻikoʻi, i ka pili me nā mea nui, a hoʻohana nui ʻia me ke kipi ʻana o nā kino o loko, aʻala neurological.

I waena o nā kaupalena ʻana i ka lawe ʻana i ka lāʻau lapaʻau, mea kūpono e hōʻike i ka:

• ka maʻiʻuhū a me nā hypersensitivity i nā mea i hana ʻia ai ka lāʻau lapaʻau,
• kaʻeha hoʻonāukiuki i loko o ke kino e pili ana i ka hana hewa o nā aʻa endocrine (pancreatitis, malfunction o ka thyroid gland, pancreatic necrosis, pathology of adrenal cortex),
• ʻO ka lāʻau a me ka hōʻeha o ka puʻuwai, nā maʻi hoʻohui o ka tractary tract (cirrhosis, hōʻeha o ka ate, hepatitis B a me C),
• pilikia hōʻeha nui loa, a me ka hana i ke kaʻina hana o ka filtration hana - hemodialysis,
• ka manawa hapai, mai ka mea ʻaʻohe kumu kumu hōʻike i nā hopena ma luna o ka pēpē. Ke kūlana kahi i loaʻa ai ka pōmaikaʻi i ke olakino a me ke ola o ka makuahine ma mua o ka piʻi ʻana o ka hōʻeha ʻana i ka ʻōpū, ua ʻōlelo ʻia ʻo Gabapentin ma hope o ke kūkā ʻana me ke kauka i hāpai ʻia me ka wahine.
• ka manawa a ka umauma, no ka mea, ʻaʻohe data e pili ana i ka ulu ʻana o ka pēpē. Ma ka hoʻomohala ʻana i ka lāʻau lapaʻau, ua hōʻike ʻia no ka pili ʻana o nā mea ikaika i ka waiū umauma,
• kanaka i lalo o 12 mau makahiki no ka mālama ʻana i ka mākaukau paʻa.
• ʻeha i ka ʻāina lumbar ma hope o ka hū ʻana o ka herpetic o nā shingles i nā makahiki he 18 o ka makahiki.

Dosis no nā pākeke a me nā keiki

Hoʻokumu ka papa hana hōʻike ma ka ʻano etiological a me nā hōʻike o ke kuʻuna. Hōʻike ʻia nā loina maʻamau no ka heluʻana i ka hala i ka papa.

ʻAʻole kuhikuhi ʻia ka lāʻau lapaʻau no nā keiki ma lalo o ka 12 mau makahiki me ka hopu ʻana e hoʻomanawanui, ʻo ka nui o ka hopena ma kahi keiki ʻaʻole ʻokoʻa i kēlā mau mea maʻi - 900 mg i ʻekolu mau huahele neʻe, akā ʻo ka nui loa - 2400 mg i ʻekolu mau māhele pae ʻokoʻa (3600 mg ma hope o 18 mau makahiki).

No ka mālamaʻana i ka hoʻohui waiʻona

Ua hōʻike ʻia nā haʻawina me kahi pūʻulu manaʻo i nā mea maʻi i lawe i ke ʻano o ka lapaʻau no 3 mau malama e mālama i ka hilinaʻi i ka waiʻona i hōʻike ʻia ka hōʻemi ʻana i ka inu ʻawaʻawa a me ka hoʻokū ʻana i ko lākou kūlana noʻonoʻo (e lawe ana i kahi mahele maʻamau o 300 mg ʻekolu mau manawa i ka lā).

Me ka piʻi o ka waiū i ka 600 mg ʻekolu mau manawa i ka lā, ʻaʻole ka nele o ka minamina no ka ʻawaʻawa, akā ʻo ka normalization o ka hiamoe, 46% haʻalele loa i ka inu, a me ka pae ʻana o ka naʻau pae maikaʻi i hoʻonui ʻia e 15% (i hōʻemi ʻia ke kaumaha, irritability, agresi).

Kōkua ʻo Gebapentin e hakakā i ka waiʻona.

Pehea e kāpae ai i ka lāʻau lapaʻau?

Ke papa ʻia ka lāʻau hiki ke hoʻopau koke i ke ʻano, ke nānā ʻana o ke kuʻina o ke kāpae ʻana a me ka hoʻomohala ʻana i nā hoʻopiʻi mai ka palema ʻana o ka neurological he ʻano - mai ka hopohopo, ke hoʻouka ʻana, ka puʻu ʻana, me nā hanana ʻana o ka hallucinations a me ke kūkulu ʻana i ke kūlana epileptic.

ʻO ka hopena ʻoi loa ka hoʻololi iki ʻana i nā kao pau aʻe ma luna o 7-10 mau lā, ma nā palena kiʻekiʻe a me ka hoʻohana wā lōʻihi no kekahi mau makahiki, hiki ke hoʻopau ʻia ke kaʻina hana a hala i hala mau mahina a hiki i ke kīleʻaleʻa ke neʻe nei.

Hiki paha nā hopena ʻaoʻao a overdose

Ma ka hihia o ka hōʻino ʻana i ka hoʻoponopono dosage, nā lāʻau lapaʻau ponoʻī, ka hoʻomehana ʻole o kēlā me kēia lāʻau a me kāna mau mea, ʻo nā hopena ʻino loa mai nā ʻano kūloko o ke kino e kū mai:

Ke nānā ʻia nei kahi overdose o ka lāʻau i ka wā i hoʻonui ʻia ai ke ʻano lāʻau i hōʻike ʻia e hōʻike ʻia e ke kiʻi e like me kēia.

• cerebralgia,
• ʻike wua
• hoʻoweliweli a ka ʻalae huʻu (hoʻopuka, hoʻāla),
• nā hōʻailona neurological (ʻ drlio, hoʻokaʻawale, stupor, stupor, coma),
• nā hoʻonāukiuki i ka lewa a me ka manawa.

Hoʻomaka ka hoʻomaʻamaʻa ʻana i ka gastage lavage a me ka hōʻoluʻolu o nā hōʻailona, ​​ʻaʻole pono nā antidotes. Hoʻouna ʻia ka mea maʻi i kahi haukapila e hoʻoponopono i ke kūlana a nānā i ka kūlana o ke olakino.

He hopena ncotic anei ia?

ʻAʻole hōʻola ka lāʻau lapaʻau i ka hopena narcotic, ʻoiai he mea ʻokoʻa ka ka hana o ke ʻano ma ke kino i ka hopena o ka hōʻeuʻeu ʻana o nā ʻenehana opioid. ʻAʻole ia he kumu a ka euphoria, akā e hoʻokō i ka hopena analgesic.

ʻO kahi hiʻohiʻona hiʻohiʻona o Gabapentin ʻo ia me ka piʻi nui o ka nui, ka hopena, ma ka ʻokoʻa, ʻaʻole i emi.

Hoʻopili pū me nā lāʻau ʻē aʻe

Pono e hoʻohana pono ka lāʻau lapaʻau me nā lāʻau ʻē aʻe a mālama i ka hopena o ka hoʻopili ʻana.

1. ʻO ka Morphine a me nā narcotic analgesics - ʻaʻole e hoʻopilikia i kekahi i kekahi, kahi kūlike ʻokoʻa me ka pale ʻole a i ka hoʻonui ʻia ʻana o ka hopena o ka hoʻohana ʻana i ʻelua mau lāʻau i ka manawa like.
2. Hoʻopae ka komoʻana me nā antacids i ka hana o Gabapentin ma ka 15-30%.
3. ʻO ka emi ʻana o ka hana hoʻopau i ka lākō o ka lālani ke nānā ʻia ke hui ʻia me nā lāʻau e pili ana i ka cimetidine.

Nā ʻōlelo kikoʻī

Hoʻohana me ka mālama pono ʻana i ka hele ʻana o nā hana ʻeha i loko o ke kino, me ka hoʻōla ʻana o ka pancreas, he mea lohi ke hoʻolōʻihi i ka lāʻau lapaʻau i mea e pale aku ai i ke ʻano a me ka hoʻonāukiuki ʻana i nā kauā.

ʻAʻole hoʻohana ʻia ʻo Gabapentin no ka mālama ʻana i ka epilepsy abscess. I ka wā o ka mālama ʻana, pono e hoʻokaʻawale kekahi mau hana: ka hoʻokele ʻana i nā kaʻa, ʻoi aku ka wā e hana pū me ka lawe ʻana i ka lehulehu, a hoʻopaʻa ʻia ka hana me nā mea e hiki ai ke nānā ʻia, a e koi ana i ka neʻe ʻana o ka nānā pinepine ʻana, no ka mea, e emi ana ka hopena o ka hopena me ka nui o nā hana hōʻemi i ka cerebral cortex.

Nā hōʻike o nā loea a me nā maʻi āpau

He mea maikaʻi loa nā loiloi o nā kauka e pili ana iā Gabapentin, ka hoʻohālikelike ʻana o ka laʻana i ka pae o ka hana i ka hopena o ka hōʻike mau ʻana.

ʻO nā loiloi o nā mea maʻi i lawe iā Gabapentin no ka hoʻomaha ʻana o ka hōʻeha o ka maʻi neuropathic ma ka hapanui o ka nui, he maikaʻi nā maʻi, ʻike ʻia nā mea maʻi mai ka lawe ʻana i nā papa Gabapentin mai ka papa gastrointestinal a me nā maʻi neurological, a ua ʻike pū ʻia ka addict wikiwiki. Ma hope o ka pau ʻana o ka papa o ka mālama ʻana, ua hoʻomaopopo ʻia nā loli o ke ʻano o ka hiamoe, ke kaumaha a me ka hiamoe mau ana.

Igor, 31 makahiki: "Ua hoʻomaka maoli ka mea hoʻohui, ua paʻakikī ʻo ka ʻai ʻana me ka ʻai ʻole, a laila e noʻonoʻo. ʻAi wau i kahi pilikia hiki ʻole iaʻu ke hōʻole i ka lawe i nā pōpoki, ʻaʻole loa wau e nele - e like me ka ʻano o ka lāʻau lapaʻau.

Kūʻē kaʻu keʻokeʻo ma 400 mg ʻekolu mau manawa i ka lā no ka makahiki ʻehā. I kēia manawa ʻike wau ke kaumaha wau i nā moʻo kaumaha a me ka suicidal i loko o koʻu poʻo. Hōʻalo nā manaʻo, ʻo ka manaʻo i nalowale wau i koʻu manaʻo a ke manaʻo nei kekahi iaʻu. I kēia manawa ua hele nei ke kauka i ka mālama ʻana i ka psychiatric. "

ʻO Gabapentin kahi lāʻau lapaʻau maikaʻi no ka hoʻopauʻana i nā mea hoʻonāukiuki, e pani ana i ka hōʻeha o ka neuropathic a pale i nā kuʻekuʻe epileptic. Kuhi ʻia nā kānāwai o ka hoʻokele a me nā regimens dosage, hiki ke hoʻokō nui loa i ke kala ʻana o nā maʻi o kahi ʻano neurological me nā hopena ʻole a me nā haunaele ma ka ʻaoʻao o ke kino.