ʻO ka lāʻau Lovastatin: ka hana o ka hana a me nā loiloi

ʻO ka pilikia me ka cholesterol koko kiʻekiʻe e hopohopo nei i nā poʻe he nui. ʻO kēia ma muli o ka loaʻaʻana o ke ʻano i hiki ke alakaʻi i nā hewa o ka puʻuwai a me ka ʻōnaehana vascular ma kahi holoʻokoʻa. E hoʻopau i ka hyperlipoproteinemia, pono wale nō e ʻai i ka ʻai, akā e lawe pū kekahi i nā lāʻau lapaʻau.

ʻO ke ala e ʻoi ka hopena o ke koko haʻahaʻa e mālama ʻia i ka lāʻau "Lovastatin." E hōʻike ʻia nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana, ke kumukūʻai, nā loiloi, nā analogues a me nā contraindications o kēia lāʻau lapaʻau ma lalo nei. E aʻo ʻoe e pili ana i nā mea a ka poʻe loea e ʻōlelo ai e pili ana iā ia a me ke ʻano o ka pane ʻana o nā mea kūʻai mai.

Hōʻailona, ​​mea kāpili, ka hoʻopili a me ka wehewehe o ka lāʻau lapaʻau

ʻO ka lāʻau lapaʻau "Lovastatin", nā ʻōlelo aʻo no ka hoʻohana ʻana ia mea e kālai ʻia i ka pahu pepa, kūʻai ʻia i ke ʻano o nā papa keʻokeʻo a me nā ʻihi. ʻO ke ʻano ikaika i kēia lāʻau lapaʻau ka lovastatin. Aia no nā mea kōkua, loaʻa iā lākou ka lactose monohydrate, starch, cellulose, ascorbic acid, butyl hydroxyanisole, citric acid a me ka magnesium stearate.

Hoʻokuʻu ʻia ka lāʻau lapaʻau i loko o nā poli a me nā ʻihi pepa o kēlā

Ke ʻano o ka hana o ka lāʻau

He aha ke kumu o ka hana a ka lāʻau lapaʻau "Lovastatin"? Nā ʻōkuhi no ka hoʻohana, hōʻike i ka abstract e mālama ʻia ana e ka pale o ka ʻĀpana o ka puʻuwai ka ʻike o nā lipoproteins i ke koko. Kūkū ʻia lākou mai ia mea ma o ka launa pū me nā mea i haʻi ʻia. I ka hopena, ke hoʻohuʻāʻa ʻia ka kolamu ma nā pūpuna o nā ate.

ʻO ke kumu o ka hana o ka lāʻau lapaʻau e nīnau ʻia nei e ka hoʻihoʻi ʻana o ka 3-hydroxy-3-methylglutaryl-coenzyme A reductase. He mea ʻōmaʻomaʻo kēia me ka komo pū o ka mea i lawe ʻia ke kāpili o ka kolamu.

ʻO ka hōʻemi i ka hoʻokumuʻana o ka cholesterol e hoʻopiʻi i ka hoʻonui uku uku i ka nui o nā mea ʻaeʻa o nā elele i hoʻopaʻa ʻia i nā hepatocytes. Ma muli o kēia hopena, ke hoʻoneʻe ʻia ke kaʻina hana o nā lipoproteins haʻahaʻa haʻahaʻa mai ke koko, a ua hōʻemi ʻia hoʻi ka nui o nā kolamu, nā haʻahaʻa haʻahaʻa a me ke kūmole kaulike waena.

Nā hiʻohiʻona o ka lāʻau lapaʻau

He aha nā waiwai ʻē aʻe i loaʻa nā papa Lovastatin? Hōʻike nā ʻōlelo no ka hoʻohana (kumukūʻai, ke hōʻike ʻia nei nā loiloi ma ka hopena o ka atikala) e hiki i kēia mea hana ke hōʻemi i nā kiko o ka apolipoprotein B a me nā triglycerides, me ka hoʻonui pū i ka pae o ka lipoproteins kiʻekiʻe.

ʻO ka hopena therapeutic ma hope o ka lawe ʻana i ka lāʻau lapaʻau e nānā ma hope o ʻelua pule, a me ke kūpono - ma hope o hoʻokahi mahina a me ka hapa. Eia naʻe, hoʻomau ia no ʻeono mau pule ma hope o ka hoʻokuʻu ʻana o ka lāʻau.

ʻAʻole emi ka hopena o ka lāʻau me ka hoʻohana lōʻihi. Pono e hoʻomanaʻo ʻia ua loaʻa mai ka biocultures o Aspergillus terreus a me Monascus ruber.

ʻO nā waiwai Kinetic

Pehea ka lōʻihi o ka lā o Lovastatin? Kahi ʻōlelo no ka hoʻohana ʻana (ʻaʻole i kiʻekiʻe nui ke kumu kūʻai o ka lāʻau) i ka lilo ʻana o ke ʻano o kēia lāʻau mai ka digestive tract. Eia kekahi, hōʻemi ia i ka hoʻokomo o nā papa i ka ʻōpū ʻole.

He haʻahaʻa loa ka bioavailability o kēia lāʻau lapaʻau (ma kahi o 30% o ka nui i lawe ʻia). Ma hope oʻehā mau hola, ua hoʻokō ʻia ka ʻike kiʻekiʻe loa o ka lāʻau i loko o ke koko. Ma hope o kekahi lā ua hoʻemi ia a ua kokoke ka 10% o ka nui.

ʻO ka lāʻau lapaʻau i nīnau ʻia he 95% hoʻopaʻa ʻia i nā protein plasma. ʻO ka wehe ʻana o ka lāʻau lapaʻau me ka pākahi hoʻokahi e mālama ʻia ma ka lā 3 o ka lā.

He aha ka lāʻau lapaʻau Lovastatin? Nā ʻōkuhi no ka hoʻohana ʻana i nā hōʻike pili o kēia mea he mea kūʻai ka huahana. Ma hope o ka pauahi ʻana ma ka ate, pono ia i kahi ʻano ikaika.

Hoʻopiliʻia ka lāʻau ma waena o nā isoenzymes. ʻO kona hapalua mau ola he 180 mau minuke. ʻO ka mea hana o ka lāʻau lapaʻau, me kāna mau metabolites, kahi a pau i ka hoʻoulu ʻia e nā keiki a ma o nā ʻāpana.

Nā hōʻailona no ka lawe ʻana i nā pōpoki

I mua o nā kūlana i kuhikuhi i nā mea maʻi Lovastatin nā papa? Ua hōʻike ʻia nā ʻōkuhi no ka hoʻohana (wehewehe, ka hoʻohui ʻana o ka lāʻau lapaʻau i ka hoʻomaka mua o ka ʻatikala) e hōʻike ana he mea maikaʻi loa kēia lāʻau lapaʻau no ka hypercholesterolemia primer (type IIb a me ke ʻano IIa lipolipoproteinemia) me kahi kikoʻī LDL kiʻekiʻe (inā i mālama ʻia ka lāʻauʻai i ka poʻe me ka nui o ka piʻi ʻana o ka atherosclerosis coronary) , me ke ʻano pū me hypertriglyceridemia a me hypercholesterolemia.

Pono e hoʻomaopopo ʻia ka lāʻau lapaʻau e nīnau nei i pinepine i ka atherosclerosis.

Nāʻano hoʻohālikelike no ka lawe ʻana i nā huahana

I nā hihia hea ʻaʻole i hāʻawi ʻia ka mea maʻi e hoʻohana i nā papa Lovastatin? Nānā i nā ʻōlelo aʻoaʻo (ke ʻano me kēia lāʻau lapaʻau e kuhikuhi wale ʻia e ke kauka) hōʻike ʻo kēia lāʻau lapaʻau e contraindicated inā ʻeha o nā maʻi o ka puʻuwai, hāpai ʻia a i ʻole kona hopena, hoʻonui ʻia ka transaminases o ka kumu maopopo, ʻoiai i ka wā e hoʻolako ʻia ai, i kahi kūlana koʻikoʻi o ka mea maʻi (ka ʻā) a nui a nui aʻe ka hoʻowali ʻana i ka lovastatin.

Eia kekahi, ʻo ka lāʻau lapaʻau i nīnau ʻia ʻaʻole i kuhikuhi ʻia i ka wā ʻuʻuku, me ka myopathy a me cholestasis.

Lā ʻia ka hoʻohui ʻana i ka ʻai me nā mea inu wai. Me ka nui o ka makaʻala, ua kuhikuhi ʻia i nā poʻe maʻi ma hope o ka coronary artery bypass grafting.

Keʻano lāʻau "Lovastatin": kuhikuhi i ka hoʻohana

ʻO ke kumukūʻai, nā mea hoʻohālike o kēia pono hana e noʻonoʻo iki.

E like me nā ʻōlelo i hoʻopili ʻia, pono e lawe ʻia nā papa Lovastatin i ka wā pāʻina ʻana i ka lā hoʻokahi.

I ke ʻano o kēia pathological e like me ka hyperlipidemia, ua kuhikuhi ʻia ka lāʻau lapaʻau ma ka huina o 10-80 mg hoʻokahi (ʻo ke ʻano ka mea i kau ʻia ma ka nui o ka maʻi).

Hoʻomaka me ka lāʻau lapaʻau i ka nīnau ma nā wahi liʻiliʻi. A laila hoʻonuiʻia. ʻO ka nui o ka lā ma mua o ke ʻano o ka lāʻau lapaʻau, e like me ka 80 mg, hiki i ka manawa hoʻokahi a ʻelua paha i ka lā (i ke kakahiaka a ma mua o ka moe. Ke koho nei ke koho ʻana he hopena pākiha a me kahi manawa o hoʻokahi mahina.

Pehea e kauoha ʻia ai ʻo Lovastatin no ka atherosclerosis coronary? Nā ʻōlelo kikoʻi no ka hoʻohana ʻana i ka hōʻike e like me kēlā maʻi, ʻōlelo ʻia ka lāʻau lapaʻau ma loko o kahi hapa o 20-40 mg. Inā ʻaʻole pono ka nui o ka lāʻau i hōʻike ʻia, a laila hoʻonui ʻia i ka 60-80 mg.

Ke hoʻohui ʻia ka lāʻau lapaʻau me nā fibrates a i ʻole ka nikotinic acid, ʻaʻole ʻoi aku kona nui ma mua o 20 mg i ka lā.

Nā hanana pōʻino

No nā hopena Lovastatin ka hopena i nā ʻaoʻao? ʻO nā ʻōkuhi no ka hoʻohana e hōʻike i nā hanana pōʻino e hiki mai ana:

  • katarata, wahī,
  • optic atropa, dizziness,
  • insomnia, pilikia hiamoe, hopohopo, nāwaliwali laulā, paresthesia,
  • wahī wahī, myalgia, myositis
  • nā mea e lawe ana i ka acid nikotinic, Cyclosporin a i ʻo Gemfibrozil, e hoʻonui i ka hōʻeha o ka rhabdomyolysis,
  • thrombocytopenia, hemolytic anemia,
  • ʻĀpana, biliest cholestasis, nausea, hepatitis, flatulence, ʻono hoʻoweliweli, constipation, cholestatic jaundice, ʻeha, ʻeha,
  • i nā hana e hoʻonui ai i ka phosphokinase a me nā melaminases,
  • ka hoʻonui ʻana o ka bilirubin a me ka phosphatase alkaline,
  • ʻO ka edema o Quincke, pāheʻe, ʻeha, arthralgia, urticaria,
  • alopecia a hoʻemi i ka potency.

ʻO kahi lāʻau hoʻonui nui

Me ka hoʻomoʻi ʻole o nā lawelawe ʻana i ka nui o ka lāʻau, ʻaʻole ʻike ʻia nā hōʻailona kikoʻī i ka mea maʻi.

I ka nānā ʻana i nā kūlana patological, holoi ʻia ka mea ʻai me ka ʻūhā a kuhikuhi i ka komo ʻana i nā ʻōpū. No laila, ka mālamaʻia o ka mea maʻi no nā hana nui, ka hana ʻalike a me ka hana phosphokinase hana.

Hoʻohui nūhou

ʻO ka hoʻohana pinepine ʻana i ka nui o ka wai o ka ʻai, a me ka Gemfibrozil a me Fenofibrat, e hāʻawi i ka hopena kiʻekiʻe o ka hoʻomohala ʻana i nā myopathies.

ʻO ka lawe ʻana i ka lāʻau lapaʻau me ka acid nicotinic, Clarithromycin, Erythromycin, Cyclosporin, lāʻau lapaʻau antifungal (Itraconazole, Ketoconazole), Apanzodone a me Ritonavir alakaʻi i kahi hoʻonui i ke komo ʻana o ka lāʻau lapaʻau i loko o ke koko, a me ka luku ʻana i ka naʻau. nā kiko a me ka pilikia o ka hoʻomohala ʻana i ka myopathy.

Hoʻokomo pū ka hoʻokele ʻo "Lovastatin" me "Warfarin" i ka hopena o ke kahe.

ʻO ka lāʻau "Colestyramine" ho'ēmi i ka bioavailability o ka lāʻau i ka nīnau. No laila, ʻo ka manawa manawa ma waena o kā lākou hana e hōʻuluʻulu ma kahi o nā hola 2-4.

ʻO ke kumukūʻai o ka lāʻau lapaʻau a me nā kūmole

I kēia manawa, ʻaʻole hiki ke kūʻai aku i nā lāʻau lapaʻau i nā lāʻau lapaʻau ma Moscow a me nā kūlanakauhale o Rūsia. Inā kūpono, hiki ke kauoha ʻia ma o ka World Wide Web. Hoʻololi ākea nā kumukūʻai ma nā lāʻau lapaʻau pūnaewele. Hiki ke kūʻai ʻia kēia lāʻau lapaʻau i ka palena o 300-600 rubles.

Inā pono, a hiki ke hoʻololi ʻia ka lāʻau lapaʻau i nā lāʻau like ʻole e like me Apextatin, Fluvastatin, Cardiostatin, Iinvastin, Vero-Lovastatin, Pravastatin, Holetar, Lovasterol, Mevacor , Mevinacor, Lovacor.

Nā Hōʻike Hoʻomaʻi

I kēia manawa ʻike ʻoe i ka mea e like me nā Lovastatin. Ua wehewehe ʻia nā ʻōkuhi, ka hoʻonohonoho, hoʻohana, nā like o nā lāʻau lapaʻau i kēia ʻatikala.

Wahi a nā poʻe loea, hoʻohana ʻia nā lāʻau lapa lalo-lipid i ka mālama paʻakikī, me ka hoʻokaʻawale ʻana o ka atherosclerosis a me nā mea hoʻohui.

ʻO ke kumuhana o ka hana o kēia lāʻau lapaʻau ka hōʻemi ʻana i nā mea o nā lipoproteins atherogenic i ke koko

Wahi a nā kauka, i kēia manawa ua loaʻa ka ʻike nui ma ka hoʻohana ʻana i Lovastatin. ʻO ia kekahi o nā lāʻau lapaʻau palekana loa. Loaʻa i kēia lāʻau lapaʻau ke kūleʻa maikaʻi loa i ka wā lōʻihi.

Kuhi hewa nā hopena ʻaoʻao i nā loiloi hoʻomanawanui. I kekahi manawa hiki i kēia lāʻau lapaʻau ke hōʻeha i ka lemulewa, ka maʻi ʻeha, ka ʻeha o ka ʻōpū, constipation, insomnia a me ka ʻehaʻeha o ka naʻau. ʻO ka maʻamau, ua nalowale kēia mau hopena i nā hebedoma ma hope o ka hoʻomaka ʻana o ka lapaʻau a ma muli o ka hōʻemi ʻana o ka hopena.

ʻO ka lāʻau Lovastatin: ka hana o ka hana a me nā loiloi

ʻO ka hui o statins (pauku-hōʻemi i ka lāʻau lapaʻau) hoʻohui pū me Lovastatin ka hopena. Hoʻohana ʻia ka lāʻau lapaʻau ʻaʻole wale nō ma ka mālama ʻana o hypercholesterolemia, hyperlipoproteinemia, akā i ka pale ʻana o nā maʻi cardiovascular.

Pono e hoʻohana ʻia ka lāʻau lapaʻau me ka hui pū me kahi meaʻai kūikawā, hoʻomaʻamaʻa a me ka hoʻoponopono pono ʻana. I kēiaʻatikala, hiki iā ʻoe ke aʻo hou e pili ana iā Lovastatin, nā ʻōlelo no ka hoʻohana ʻana, nā kumukūʻai, nā loiloi, nā loiloi.

Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau

Hoʻokomo ʻia ka Lovastatin 20 mg a i 40 mg paha ma kahi puka papa, ka mana ikaika o ia mau inoa like. ʻO nā mea waiwai'ē aʻe o ka lāʻau lapaʻau ka lactose monohydrate, starch, cellulose, magnesium stearate, butylhydroxyanisole, citric a me ascorbic acid.

Ke kūʻai lilo aku nei ka lāʻau lapaʻau inā loaʻa ke kanaka i kahi lāʻau lapaʻau me ia. I ke kūʻai ʻana i ka lāʻau lapaʻau, pono nā mea maʻi e makaʻala i ka hoʻopili paʻa. He nui nā hōʻike e aʻo ai no ka hoʻohana ʻana i kēia lāʻau lapaʻau.

  • ka hana ʻana o ka hypercholisterinemia ʻano maʻamau IIa a me IIb,
  • maʻiʻo hyperlipoproteinemia (paʻakikī me ka maʻi maʻi a me ka nephrotic syndrome),
  • ka mālamaʻana i ka atherosclerosis coronary (me ka lāʻau o ka waiū a me nā momona momona unsaturated),
  • ka pale ʻana o nā alele ma ka maʻi cardiovascular,
  • hoʻokūkū maʻi hypertriglyceridemia.

Pono ka hoʻohana ʻana i nā papa i hoʻokahi manawa i kēlā me kēia lā i ka ʻaina ʻaina. ʻO ka hopena o ka lāʻau lapaʻau e hilinaʻi ʻia i ka maʻi. No laila, me ka hyperlipidemia, kahi kikoʻī hoʻokahi o 10-80 mg i kuhikuhi ʻia.

Hoʻomaka ka hoʻokaumaha o ka pathology me nā liʻiliʻi liʻiliʻi, me ka ʻae a ke kauka, hiki ke hoʻonui iki ʻia. A ʻoi ʻia e koho i kahi kao i kēlā me kēia 4 hebedoma.

Hiki ke hoʻokaʻawale ʻia ke ana ka nui (80 mg) i ʻelua mau puʻupuʻu - i ke kakahiaka a me ke ahiahi.

I ka loaʻa ʻana o ka atherosclerosis coron, ʻo ka nui loa ma ka nui o 20-40 mg. Inā maikaʻi ʻole ka lāʻau, hiki i kahi hoʻonui o 60-80 mg hiki. Inā lawe ka mea maʻi i ka fibrates a i ka acid nicotinic i ka manawa like, pono e hoʻohana ʻia ʻo Lovastatin ma mua o 20 mg i ka lā. Eia kekahi, pono ke hōʻemi ʻia o ka dosage i ia mau hihia:

  1. Hoʻohana pinepine ʻia nā immunosuppressants.
  2. ʻO ka hoʻohana ʻana i nā mea hoʻohui antibiotika.
  3. Therapy me nā lāʻau antifungal.
  4. Mahele o nā maʻi ate o ka etiology a maʻa paha.
  5. ʻO ka hoʻohana ʻana i nā lāʻau lapaʻau e loaʻa ana nā anticoagulants.

Pono e mālama i ka lāʻau lapaʻau i kahi mahana ʻaʻoleʻoi aʻe ma mua o 25 tikelika Celsius.

Ma hope o ka lā pau, kahi 2 mau makahiki, pāpā ʻia ʻole ia e hoʻohana i ka huahana.

Nā hiʻohiʻona a me nā hopena ʻaoʻao

Lovastatin kahi papa inoa liʻiliʻi o nā contraindications. Ua papa ʻia ka hoʻohana ʻana o ka lāʻau lapaʻau ma ka hihia o ka maʻi myopathy (maʻi neuromuscular maʻi), hapai, cholestasis, ate ate, ma lalo o nā makahiki he 18 a me ka hypersensitivity pilikino i nā mea.

Pono e hoʻohana ʻia ka lāʻau lapaʻau me ka mālama ʻana i nā maʻi i hana i ka coronary artery bypass grafting. No ka mea e pono ai e inu i ka lāʻau lapaʻau me ka waiʻona.

I kekahi mau hihia, hiki i kahi lāʻau lapaʻau ke hōʻeha i nā hopena ʻaoʻao. I waena o lākou, pono e hōʻike i:

  • ʻO nā hopena pili i ka hana o ka ʻeha gastrointestinal: hōʻeuʻeu o ka ʻōpū, ka puʻuwai, ka hoʻonui ʻana i ke kinoea, he hoʻololi i ka ʻono, ʻeha, hoʻohuli i ka constipation.
  • Nā hemahema o ka pūnaehana nīnaehana: nā hōʻeha, ka hiamoe maikaʻi, ka hopohopo, ka ʻilihune, paresthesia, myositis, nā ʻōpū o ka naʻau a me ka myalgia. Ke hoʻohana nei i ka cyclosporine, gemfibrozil a i hamotinic acid, hiki i ka nui o ka rhabdomyolysis.
  • ʻO nā hopena o ka ʻōnaehana biliary: ka hana i hoʻonui ʻia o ka bilirubin, ka phosphatase alkaline, nā transaminases ate a me ka phosphokinase creatine. I kekahi manawa hepatitis, jaundice cholestatic a me nā cholestasis biliary.
  • He maʻi kūlohelohe: itching, lapalapa ʻili, urticaria, angioedema, arthralgia.
  • ʻO ka hikiʻole o nā maka kuʻekuʻe: atraph o ke aila optic a me ka hoʻomohala ʻana i nā cataracts.
  • ʻO nā hopena ʻē aʻe: ua hoʻemi i ka potency, ka malaise maʻamau, alopecia.

ʻAʻole ʻike ʻia nā hōʻailona o kahi overdose i ka wā e hoʻohana ai i nā pona he nui o ka lāʻau lapaʻau. ʻO ke kumu o ka hana maʻi, ʻo ia ka hoʻopau ʻana i ka Lovastatin, gastage lavage, ka hoʻohana ʻana i nā sorbents (activated carbon, Smecta, Polysorb, Atoxil) ka mālama ʻana i nā hana koʻikoʻi, hana ate a me ka hana o ka phosphokinase hana.

Hoʻohui a me nā ʻano ʻē aʻe

ʻAʻole pono e hoʻohana Lovastatin me nā lāʻau āpau, no ka ʻo kā lākou pilina hiki ke alakaʻi i nā hopena maikaʻi ʻole o ke kino. Eia kekahi, hiki i kekahi mau lāʻau lapaʻau ke hoʻonui i ke kao o ka waiwai hana, a hiki ke emi i kekahi.

Hōʻeha ka nui o ka luku ʻana i ka musi a me ka myopathy, a me ka hoʻonui ʻia ʻana o ka ʻike o ka māhele ikaika, e hoʻonāukiuki i ka hoʻohana ʻana o Lovastatin me ka waikika nicotinic, Cyclosporine, Ritonavir, Erythromycin, Fazodone a me Clarithromycin.

ʻO ka hoʻohana pinepineʻana i kahi lāʻau lapaʻau me ka wai huaʻai, fenofibrate, gemfibrozil e hoʻonui pū i kahi manawa o ka myopathy.

Hōʻalo ka pilikia o ke koko me ka hoʻohana hoʻopukapuka ʻana o warfarin. Hoʻemi ka bioavailability o lovastatin i ka wā e hoʻohana ai i ka colestyramine. I mea e mālama ai i ka bioavailability o ka lāʻau lapaʻau, pono ia e hoʻohana i nā lāʻau lapaʻau me kahi huakaʻi o nā hola 2-4.

Me nā maʻi hoʻopuni, pono e ʻōlelo ka mea maʻi e nīnau aku i ke kauka e pili ana i ka lawe ʻana i nā lāʻau lapaʻau.

ʻO kekahi o lākou ʻaʻole i kūlike me Lovastatin, no laila, pāpā paʻa ke hoʻohana kūʻokoʻa.

ʻO ke kumukūʻai, nā mea hoʻohui a me nā loiloi hoʻomanawanui

ʻO ka mea pōʻino, hiki i kēia wā ke kūʻai aku iā Lovastatin no ka ʻAʻole hana ia ma Rūsia.

ʻO nāʻoihana lapaʻau e like me Lekpharm (Belarus), Replekpharm AD (Makedonia) a me Kievmedpreparat (Ukraine) nā mea hana o ka lāʻau.

Ma kēiaʻano, hiki i ke kauka ke kuhikuhi i kahi mea hoʻohālikelike o Lovastatin, nona ka ʻano like me nā therapeutic.

ʻO nā lāʻau lapaʻau kaulana loa:

  1. ʻO Holetar. Loaʻa i ka mea hana - lovastatin, no laila he mea hoʻohui a Lovastatin. Ke hōʻike nei ka lāʻau i nā hōʻailona like, nā contraindications a me nā hopena ʻino e like me Lovastatin.
  2. Cardiostatin. ʻO kekahi lāʻau lapaʻau maikaʻi loa i kapa ʻia ka Lovastatin, no ka mea piha ka mea hana like. Ke lawe nei iā Cardiostatin, he hopena therapeutic i haʻi ʻia i mālama ʻia no nā pule he ʻelua, a ʻo ka nui ma hope o ka 4 mau hebedoma o ka lawe ʻana i ka lāʻau. ʻO ka kumukūʻai kūpono he 290 mau rubles (i loko o kahi pahu o nā papa he 30 o 20 mg).
  3. Pravastatin. He palahalaha nui o ka hana. ʻO ka pogala hoʻoikaika e pravastatinum. Hoʻohana ʻia ka lāʻau lapaʻau no ka hypercholesterolemia haʻahaʻa a me nā dyslipidemia i hoʻohui ʻia, a no ka pale ʻana o ka maʻi ischemic puʻuwai. Hiki ke hoʻohana ʻia ʻo Pravastatin ma ke ʻano he pale paʻa no ka infiction myocardial, angina pectoris a me ka hyperlipidemia post-transplant.
  4. Zokor. ʻO ka mea ikaika o ka lāʻau ka simvastatin. ʻO ka hōʻike nui o ka lāʻau lapaʻau ka mālama ʻana i ka hypercholesterolemia. Hoʻohana ʻia ʻo Zokor ma ke ʻano he prophylactic i mea e pale ai i ka hoʻomohala ʻana o nā pathologies cardiovascular. ʻO ka kumukūʻai kūpono he 380 rubles (28 mau papa o 10 mg) a me 690 mau rubles (28 mau papa o 20 mg).

Wahi a ka Vyshkovsky Index, nā alakaʻi i loko o ka mākeke lāʻau Lūkini ʻo Cardiostatin, Mevacor, Holetar a me Rovacor.

E kūleʻa ana nā ʻōlelo noʻonoʻo iā Lovastatin, mai nā mea maʻi a mai nā kauka paha. Ka palekana ka lāʻau lapaʻau a hoʻomanawanui maikaʻi ʻia e nā mea maʻi, ʻoiai me ka hoʻohana lōʻihi.

Hōʻike nā hana pili i ka maʻi dyspeptic i kekahi manawa ma ka hoʻomaka ʻana o ka hopena. Ma hope oʻelua pule, i ka manawa e hoʻohana ai ke kino i ka manaʻo o ka mea hana, kau ʻia nā hōʻailona. ʻO ka manawa, hoʻonui ka nui o ALT a me AST, no laila e pono e kāohi i kā lākou ʻike.

Ma hope o 1.5 mau mahina mai ka hoʻomaka ʻana o ka ʻoihana, hoʻomaʻamaʻa ʻia ka nānā ʻana. E like me ke kānāwai, aia kahi kūpono maikaʻi i nā kākela, i.e. hoʻemi ʻia ka ʻike lipid.

Pehea e hoʻohaʻahaʻa ai i ka cholesterol i loko o ka wikiō ma kēia atikala.

E wehewehe i kāu holi a koho ʻole paha i kahi kāne no nā loiloi: ʻaʻole i loaʻa ka ʻike ʻana.

E hoʻokuʻu i ke ʻano a me ka ʻano

Nā papa kuhikuhi o ka hoʻokuʻu ʻana o Lovastatin he papa: kahi pōpoki cylindrical, keʻokeʻo me ka tinge melemele, me kahi bevel (i loko o kahi kāwele pepa i nā ʻāpana he 10 mau papa, 10 a 20 paha i kēlā me kēia).

ʻO ka ʻōmole o 1 papa:

  • mea waiwai: lovastatin - 20 a 40 mg ((ma nā ʻōlelo o ka 100% maloʻo).
  • ʻO nā mea kōkua: colloidal silicon dioxide, magnesium stearate, mais starch, butylhydroxyanisole, microcrystalline cellulose, miki waiu.

Lapaʻau lāʻau

ʻO Lovastatin he mea pale i ka syntogenous synthesis i loko o ka ate. ʻO ka mea i loko o ke kino ma ke ʻano o ka lactone ahe ʻole i hoʻokaʻawale ʻia i ka puka ikaika e pili ana i ka therapeutically active, ka mea e hana ai i ka mea hoʻokūkū hoʻokūkū o ka 3-hydroxy-3-methylglutaryl-coenzyme-A reductase (HMG-CoA reductase). ʻO kēia kahi ʻōmaʻomaʻo e hōʻiliʻili ai i ka hoʻololi ʻana o HMG-CoA i ka mevalonate, ʻo ia ka mea mua i ka cholesterol biosynthesis.

ʻO nā hopena nui o ka lovastatin:

  • Ka hōʻemi o ka kolamu koko nui a me ka kolamu ma LDL a me VLDL (nā lipoproteins haʻahaʻa haʻahaʻa a nā lipoproteins kumu haʻahaʻa loa),
  • nāwaliwali i ka emi ʻana o ka ʻike o ka apolipoprotein B, ka ʻikeʻana o ka triglycerides i loko o ke koko koko a me ka hoʻonui ʻana i ka hoʻoulu ʻana o HDL (nā lipoproteins kūloko kiʻekiʻe),
  • plato stabilization, hoʻomaikaʻi i ka hana endothelial, antithrombogenic a me nā hopena anti-inflammatory (hāʻawi i ka hopena antiatherosclerotic).

Hōʻike ʻia ka hopena therapeutic o lovastatin i loko o nā lā 14, a me ka nui ma hope o 1-1,5 mau mahina o ka hoʻokō hoʻonohonoho. I ka manawa like ma hope o ka hoʻokuʻu ʻana o ka maʻi, hoʻomau ka hopena. Me ka hoʻohana mau ʻana (a hiki i 5 mau makahiki), ʻaʻole i emi ka hopena o lovastatin.

Lapaʻau lāʻau

Hoʻomoʻi ʻo Lovastatin i ka hana kūwili (kahi o ka gastrointestinal tract) a lohi a me ka piha ʻole - e pili ana i ka 30% o ka nui. Ke lawe ʻia ma ka ʻōpū ʻole, ua hoʻemi ʻia ke kōpono o ka 1/3 i hoʻohālikelike ʻia me ka ʻai.

ʻO Tmax (ka manawa e hiki ai i ka lōʻihi o ke kau ʻana) ka lōʻihi ma waena o 2 a 4 mau hola, ʻo Cmax (ka uka nui) ka 7.8 a me 11.9 ng / ml (no ka lovastatin a me beta-hydroxyacids), a laila emi wikiwiki ka pilina o ka plasma. Ma hope o nā hola 24, ʻo 10% nō o ka nui. Ke kamaʻilio pū ʻana me nā protein plasma koko - 95%. Me ka pākahi hoʻokahi i ka pō, ʻo ka hoʻohemo ʻana o lovastatin a me kāna mau metabolite ikaika e hōʻea ma hope o 48-75 mau hola.

Hoʻokomo ʻia ma o ke koko-lolo a me ka paepae placental.

Ke kahe nei i ka ate i ka manawa mua, ka lovastatin hele i ka metabolism kūlohelohe, hōʻiliʻawa i ka beta-hydroxy acid, kāna 6-hydroxy derivative a me nā metabolites, ʻo kekahi o lākou e hōʻike i ka hana pharmacological (hana lākou i ka HMG-CoA reductase). ʻO nā isoenzymes o CYP3A4, CYP3A7 a me CYP3A5 e komo i ka metabolism o lovastatin.

T1/2 (hapalua-ola) 3 mau hola. 83% o kahi huehue e hoʻopio ʻia ma o nā ʻōpū, 10% - e nā keiki.

Nā hōʻailona no ka hoʻohana ʻana

  • level serum level of total cholesterol, LDL cholesterol a me triglycerides i ke koko serum i nā maʻi me ka hypercholesterolemia primer (e like me nā Fredrickson ʻano IIa a me IIb), me nā famliali aila ka hyperlipidemia, polygenic hypercholesterolemia a me ka heterzygous hypercholesterolemia. o na mea ola ʻē aʻe
  • kahi atherosclerosis coronary i nā mea maʻi me ka maʻi naʻau coronary (maʻi coronary heart): e lawe ʻia ana ke kauka e lohi i kona holomua.

Hāpopo

ʻO ka dosis hoʻonaninani ʻia i kēlā lā i kēia lā ʻo Lovastatin ka 1080 mg hoʻokahi i ka lā.

I nā mea maʻi me ka hypercholesterolemia maʻalahi, mālama pinepine ʻia ka nui ma mua o 20 mg i hoʻokahi lā i ke ahiahi, me kahi ala o ka maʻi (plasma holoʻokoʻa kolamu ma ke koko - mai 7.8 mmol / l) - 40 mg. E hoʻokō i nā pae ʻai kolamu kiʻekiʻe, hiki ke hoʻonui ʻia i ka nui o 80 mg (kiʻekiʻe) i hoʻokahi a keu paha (kakahiaka a me ke ahiahi).

E hoʻololi i ka puʻupuʻu me nā mea hoʻohiki no ka liʻiliʻi loa 4 mau hebedoma. Inā hāʻule ka pae ʻai o ka kolamu nui i ka plasma koko i ka 140 mg / 100 ml a i ʻole ka LDL cholesterol i 75 mg / 100 ml, hiki ke hoʻemi ʻia ka nui o ka hoʻomālamalama o Lovastatin. Ke hui pū ʻia me ka cyclosporine, ʻo fibrates a i ʻole ka nikotinic acid (mai ka 1000 mg i kēlā me kēia lā), ʻaʻole pono ka nui o ka make ma ka 20 mg i kēlā me kēia lā. I ka poʻe maʻi me ka pilikia ʻole o ka hana ʻana me ka hoʻopukapuka ma lalo o ka 30 ml / min, ua kauoha ʻia ka lāʻau lapaʻau ma lalo o ka mākaʻi o ka maʻi (ma mua loa o 20 mg i kēlā me kēia lā).

Lovasterol - nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana

Ua hoʻohana maikaʻi kā mākou poʻe heluhelu iā Aterol e hoʻohaʻahaʻa i ka cholesterol. Ke ʻike nei i ka kaulana o kēia huahana, ua hoʻoholo mākou e hāʻawi iā i kou makemake.

Ma kēia ʻaoʻao: ʻo ka wehewehe o ka lāʻau Lovasterol, nā hopena āpau āpau, contraindications a me nā kuhikuhi i ka hoʻohana ʻana i ka lāʻau Lovasterol.

ʻO ka inoa inoa hoʻoili waiwai ʻole o ka waiwai ikaika ka ʻike kumu e pili ana i ka lāʻau. ʻO ka meaʻoiaʻiʻo, ma muli o ke kānāwai, nā hua lāʻau me nā mea ikaika e hana ʻia ma lalo o nā inoa kālepa like ʻole, ʻo ia hoʻi, ʻo ia nō ka lāʻau like, akā ua hoʻoulu ʻia e nā hui like ʻole. ʻO ia ʻo INN ka mea e hiki ai i nā kauka ke koho i ka pono kūpono mai ka nui nui o nā lāʻau lapaʻau i loaʻa ma ka mākeke lāʻau lapaʻau.

Hoʻokuʻu palapala:

Nā Palaki
1 kōpō
aloha
20 mg
10 kamepiula - nā kīpaha palemona (3) - nā ʻeke pepa.

Nā Palaki
1 kōpō
aloha
10 mg
10 kamepiula - nā kīpaha palemona (3) - nā ʻeke pepa.

Nā Palaki
1 kōpō
aloha
40 mg
10 kamepiula - nā kīpaha palemona (3) - nā ʻeke pepa.

pakuhi. 20 mg: 30 pcs.

pakuhi. 10 mg: 30 pcs.

pakuhi. 40 mg: 30 pcs.

ʻO ka maʻi Cerebrovascular: nā puka, nā kumu, nā hōʻailona, ​​ke nānā ʻana, pehea e mālama ai

ʻO ka maʻi cerebrovascular (CVB) kahi ala no nā moku cerebral, e alakaʻi ana i ka ischemia, hypoxia a me ka pale hewa ʻana o nā hana like ʻole o ke kino. Ma lalo o ka mana o nā mea maikaʻi a exogenous a me ka endogenous i hōʻino ʻia, hōʻeha ʻia nā moku cerebral, a me ka neʻe ʻana o ka cerebral.

Ke alakaʻi nei ka maʻi cerebrovascular i ka hoʻomohala ʻana o ka encircalopathy discirculatory - kahi maʻi ka holomua o ka palepale i ka palupalu o ka lolo ma ka hopena o ka maʻi vascular maʻi. Ua manaʻo ʻia kēia ʻano hoʻokele pilikia me ka pilikia o ka poʻe kahiko. I kēia manawa, "ʻōpiopio" ka cerebrovascular: ke loaʻa nei ka maʻi i ka poʻe ma lalo o ka 40 makahiki. ʻO kēia ma muli o ka nohona maikaʻiʻole, ke kaona maikaʻiʻole, kaʻai maikaʻiʻole.

He maʻi koʻikoʻi ka maʻi Cerebrovascular. Noho ʻo ia i ka Poakolu ma ke ʻano o ka make maoli ma hope o ka maʻi naʻau coronary a me ka oncopathology. ʻO CVI ke kumu o ka hopena a me ka lōʻihi o ka maʻi.

Kahi helu

Nā maʻi cerebrovascular - nā maʻi o ka ʻōnaehana kaila, ka mea:

  • ʻO nā ʻeha hemorrhagic a ischemic.
  • Ke hele nei me ka palaki discirculatory uaua o ka palaki - occlusion a vasospasm, arteritis, aneurysm.
  • Hoʻopuka intracranial.
  • Maʻi maʻi hypertensive cerebrovascular - atherosclerotic a me hypertensive encephalopathy.

ʻO nā mea nui etiological o ka maʻi:

  1. Nā hōʻeha o ka atherosclerotic o nā moku cerebral e alakaʻi i ka hoʻohemo ʻana o ka cholesterol, ka hoʻokumu ʻana i nā pākeke, kā lākou ʻili a me ka blockage, a ma hope no ke kuʻi ʻana i ka hoʻokahe koko cerebral, ka lolo o ka trophic a me ka noʻonoʻo.
  2. ʻO ka hapa o ka ʻōnaehana coagulation o ke koko, ka thrombosis a me ka thromboembolism pinepine e hoʻohālikelike i kahi mikocococulation o ka lolo.
  3. ʻO ka nui o ka pā o ka paia ma mua o ka maʻi hypertension e hōʻemi ana i ke kahe koko cerebral.
  4. Hoʻopilikia ka Vasculitis i ka hāʻawiʻana o ke koko i ka lolo.
  5. Hiki i ka Osteochondrosis ke alakaʻi i ka nele o ka vertebro-basilar a me nā pilikia o ka palu o ka pelekikene cerebral.

Hoʻokomo i nā mea hōʻike i ka hoʻomohala ʻana o ka pathology:

Ua hoʻohana maikaʻi kā mākou poʻe heluhelu iā Aterol e hoʻohaʻahaʻa i ka cholesterol. Ke ʻike nei i ka kaulana o kēia huahana, ua hoʻoholo mākou e hāʻawi iā i kou makemake.

  • Naʻi maʻi mellitus
  • Mamua
  • ʻO ka Hypercholesterolemia, dyslipidemia,
  • Nā ʻilima
  • Hypertension
  • Maʻi maʻi Ischemic,
  • ʻĀkau
  • Nā hōʻeha ʻeha Traumatic
  • ʻO ka hoʻohana lōʻihi ʻana i nā hana hoʻohālikelike waha,
  • Laula
  • ʻĀina hoʻōla
  • ʻĀpilima.

ʻĀmaʻomaʻo

ʻO ka maʻi cerebrovascular ma ka pae mua o kona hoʻomohala e hōʻike ʻia nei e nā maʻi kauka e like me kēia:

  1. Hoʻemi ka hana, hoʻonui i ka momona
  2. Pono, hiki ke ea, ʻoluʻolu ʻole
  3. ʻOhiʻeha keu
  4. Insomnia
  5. Ke ku nei ka wela
  6. Putu maloʻo
  7. ʻAnenia
  8. Palpitations puʻuwai.

I ka wā e hiki mai ana, me ka piʻi ʻana o ka naʻau hypoxia, ulu mai nā pilikia weliweli a ua ʻike ʻia nā hōʻailona koʻikoʻi: hiki ke kīloi i ka ʻike, ʻike ʻole ʻia, manaʻo hopohopo, loiloi, hoʻonohonoho, palaualelo, me ka hōʻemi o ka noʻonoʻo.

I ka maʻi, hōʻeha ka naʻau, hoʻemi ka naʻauao, ulu nā neuroses a me nā psychoses, phobias a me ka makaʻu, egocentrism, explosiveness, nawaliwali-puʻuwai ʻike ʻia. ʻO ka mea maʻi e lilo i hypochondriacal a me ka palekana. Ma nā hihia koʻikoʻi, hoʻopiʻi ka hoʻomaka ʻana, nā hooweliweli, puʻupuʻu gait, kamaʻilio i ʻole ke alo, ka neʻe a me ka hoʻowalewale i nā hōʻiliʻili o ke alualu ʻana, hōʻalo nā pehu physiological, a hoʻopilikia ʻia nā mea ʻike o ke ʻano.

ʻO ka hoʻonui hou aʻe o nā loli morphological i ka lolo lolo e alakaʻi i ka helehelena o nā ʻenekine hou i hoʻolaha ʻia a nānā ʻia - nā puʻukū cerebral a me nā hōʻeha, nā paresis a me ka maʻi pā o nā wāwae, nā maʻi pelvic, dysphagia, he ʻakaʻawa a me ka uē ʻana.

Ke hōʻike nei kēia mau hōʻailona lapaʻau i nā maʻi i ke ao holoʻokoʻa e hōʻike i kahi hōʻeha koʻikoʻi o ka pelebula cerebral - cerebrovascular stroke. Inā nalowale lākou i ka manawa pōkole, ua lana ka manaʻo hōʻeuʻeu ischemic.

Hoʻokaʻawale ʻia nā kiʻekiʻe o nā maʻi cerebrovascular:

  • ʻO CVB o ka papa mua ua puka i ʻike ʻole ʻia. Aia i kāna mau hōʻailona ma nā ʻano he nui e like me nā hōʻailona o nā maʻi ʻē aʻe a me nā mea hōʻeha.
  • Hōʻike ʻia ka pae ʻelua e nā pilikia noʻonoʻo. ʻO ka maʻi ka hōʻailona no ke kuhikuhi ʻana i ka maʻi kīnā, akā lawelawe ka mea maʻi iā ia iho.
  • ʻO ke kolu o ke kolu ʻo ka hoʻololi ʻana o ka pathology i ke ʻano o ka dementia vascular. ʻAʻole hiki i ka mea maʻi hele aku e neʻe a lele i ka lewa; pono ʻo ia i ke kōkua a me ka mālama ʻana o nā poʻe a puni iā ​​ia. Pono e kāohi i nā ʻano o nā mea maʻi.

ʻO nā mea hoʻonā maʻamau o CVB ka: stroke, hōʻemi hōʻeuʻeu ischemic, dementia, cerebrovascular coma.

Nā huapau

Hoʻopilikia a me ka mālama ʻana i ka pathology cerebrovascular e pili ana i ka neuropathologist a me nā mea maʻi vascular. Ua koho lākou i nā hana aʻoaʻo e like me nā ʻano o ke ʻano o ka maʻi, ke ʻano maʻamau o ka mea maʻi a me ka hele ʻana o nā maʻi concomitant.

ʻO ka hōʻike maʻamau o nā poʻe maʻi me CVI ka:

  1. Hōʻike koko maʻi
  2. ʻŌkuhi koko
  3. Nā kuʻina o ka prothrombin index,
  4. ʻO ka hopena serological i ka syphilis,
  5. ECG
  6. ʻĀninalysis
  7. Che-x-ray.

ʻO nā ala i manaʻo ʻia no ka hōʻike piha ʻana i ka hoʻopukapuka piha o nā maʻi cerebrovascular:

  • Hoʻokumu ʻia ka Duplex a i ʻole ka triplex angioscanning no ka maʻi maʻamau i ka CVB. ʻO ka palekana, wikiwiki loa a maʻalahi hoʻi. I kēia ala, hiki ke hōʻoia pinepine ʻia nā moku i pili ʻia, a i ʻole hōʻino ʻia i ke olakino.
  • ʻO ka Angiography kahi ala e hoʻohālikelike ai i ke ʻano loiloi x-ray o nā moku koko, e hiki ai ke hoʻoholo i ko lākou kūlana hana, ka ʻike ʻana o kahi kaʻina pili a me kona lōʻihi. Hana ʻia ka angiography Cerebral ma hope o ka hoʻokō ʻana o kahi ʻaihue kūlike i ke koko. Hāʻawi ia iā ʻoe e hoʻoholo i ke ʻano o ka mea maʻi i ka trombosis, nā lesi atherosclerotic a me ka hoʻopili ʻana i nā moku koko, oncopathology, hematoma a me aneurysm.
  • He ʻano maʻalahi a noiʻi ʻole nā ​​kumu scintigraphy o Brain scintigraphy i like ʻole contongoications a ʻaʻole ia i kumu i nā hoʻopiʻi. ʻO ka scan Nuclear kahi ala koʻikoʻi a me ka ʻike e hoʻomaopopo ai i ka maʻi cerebrovascular. Hoʻokomo ʻia kahi lāʻau lapaʻau lāʻau radioaktif i loko o kahi vein, a ma hope o 15 mau minuke e hoʻokō ʻia kahi scan. Lawa kēia manawa no ka radioisotope e pālahalaha ana i loko o ke kino a hōʻuluʻulu i loko o ke kikoʻala o nā pathologically i hoʻololi ʻia. ʻO ka kuhikuhi i kahi kaona o nā radiation e ponoʻole ai i ke kino.
  • ʻO ka ultrasound Transopanial Doppler kahi ultrasound scan o nā moku cerebral e nānā ana i ka wikiwiki o ke kahe koko a hōʻike i nā pilikia hemodynamic.
  • ʻAʻole ia he mea liʻiliʻi i ka hopena o ka maʻi ʻana o CVB ʻo MRI a me CT.

ʻAʻole hiki ke hōʻike kūʻokoʻa a mālama i ka maʻi cerebrovascular. ʻO kekahi wale nō mea akamai, mākaukau loea, ua aʻo i nā hoʻopiʻi a ka mea maʻi a hoʻopaʻa iā ia loa, e kuhikuhi i ke ʻano hoʻokō. Hoʻonui ka kūpono kūpono a me ka manawa kūpono i ka maikaʻi o ke ola o ka mea maʻi a hoʻemi i ka hopena o ka hoʻolālā ʻana i kahi kūlana hoʻoweliweli - stroke.

ʻO ka pahuhopu nui o ka mālamaʻana i nā maʻi ka hoʻopau ʻana i nā hana o ka lolo. I mea e hoʻopau piha ai i ka pathology cerebrovascular, pono ia e hoʻoholo a e kāpae i kāna kumu. Ma kahi o ke kau ʻana i nā lāʻau lapaʻau, hāʻawi ka poʻe loea i nā mea maʻi i nā mea nui e pono ai: hoʻololi i ko lākou ola, hōʻemi ka momona, ʻaʻole e inu a inu i ka wai ʻawa, ʻai maikaʻi a me ka kaulike.

ʻO ka lāʻau lapaʻau

ʻO ka nānā ākea o ka maʻi cerebrovascular e hana pinepine ʻia i ka ʻoihana neurological. Hoʻopuka maoli nā loea i nā mea pōʻino: kuhikuhi i ka lāʻau antisclerotic, hypotensive, hypoglycemic lāʻau. Ma hope wale o ka hoʻoponopono ʻana i ka hana nui ka maʻi nui a hele lākou i ka mālama pololei i nā māla.

Hoʻohui kūikawā

ʻO nā hui nui o nā lāʻau lapaʻau e hoʻomaikaʻi i ka cerebral circulation a manaʻo ʻia no ka mālama ʻana o ka cerebrovascular insufficiency:

  1. Hoʻomaikaʻi ʻo nā hāmeʻa pākaleka hāpau i ke kahe koko cerebral, ka wikiwiki o ka pulse wikiwiki, pale i ka pilina o platelet a hoʻomaikaʻi i ka hoʻopili koko. Hoʻokomo ʻia nā hopena ma ka nifedipine e lawe i nā ipu o ka lolo - Corinfar, Kardipin, nā lāʻau mai ka diltiazem hui Dilzem, Kardil. ʻO Cinnarizine a me nā mea waiwai o, ʻo Verapamil, lilo nā kaona kalaka saluran.
  2. Antioxidants. Ke kumu antioxidant ikaika e koi ʻia no ka maʻi cerebrovascular, stroke a me ka encephalopathy ʻo Cerebrolysin. Ma kahi o kahi āpau, hoʻohana pinepine ʻo Cerebrocurin a me Actovegin.
  3. Ua kuhikuhi ʻia nā antihypoxants no ka maʻi cerebrovascular - Ketoprofen, Imidazole, Mekaprin.
  4. Nā Metabolika - "Cavinton", "Sermion", "Vinpocetine", "Tanakan".
  5. Pākuʻi i nā anticoagulants - "Heparin", "Fraxiparin" a me ka pololei - "Phenilin", "Sincumar", "Warfarin".
  6. Hoʻopuka Antiplatelet - "Acetylsalicylic acid", "Curantyl".
  7. Nā lāʻau lapaʻau me ka hana hypocholesterolemic, statins - "Lovastatin", "Lipostat", "Probucol", "Tykveol".
  8. No nā huahana Nootropic - Omaron, Piracetam, Pantogam, Glycine, Phenibut.
  9. Nā lāʻau lapaʻau e hoʻoinu i nā ipu o ka lolo - Pentoxifylline, Trental, Agapurin.
  10. Antispasmodics - "Papaverine", "Eufillin", "Dibazol."

ʻO ka hana nui

ʻO ka hoʻomaʻamaʻa maʻamau o CVB ʻo ia ka hoʻohālikelike i nā hana o ka hanu waho, ka ʻōnaehana cardiovascular, ka mālama ʻana i ka homeostasis, a me ka neuroprotection.

  • No ka hana i kēia, hoʻomaʻemaʻe i ke ala, hoʻokaʻawale i ka trachea, a lawe pono i ka hoʻoliʻiliʻi o nā ʻōpū.
  • PKe hele ʻia nei nā hōʻailona o ka puʻuwai naʻau a me ka edema pulmonary, "Lasix" a me "Pentamine".
  • Hōʻike ʻia ka lāʻau antiarrhythmic no nā poʻe maʻi me nā arrhythmias cardiac. Kuhi pinepine nā lāʻau antianginal, glycosides cardiac - Strofantin, Korglikon, antioxidants.
  • ʻO "Seduxen", "Haloperidol", "Diphenhydramine", "Sodium oxybutyrate" e kōkua i ka hooki ʻana i nā hana ulu.
  • Ke pale aku i ka edema cerebral, hoʻohana ʻia ka diuretū osmotic - Mannitol, Furosemide.
  • No ka hoʻopaʻaʻana i ke koko, ʻo Atenolol, Enalapril, Nifedipine, Dibazol e kuhikuhi ʻia.
  • Ke hoʻoponopono nei i ka maʻi ma o ka metabolic e lawe ʻia ana e ka hoʻāla hou ʻana i ka nui o ka wai extracellular me nā hopena o ka Ringer, plasma, glucose.
  • Hoʻokomo pū ʻia nā maʻi lapaʻau e like me nā lāʻau anticonvulsant a me nā psychotropic, hōʻoluʻolu i ka naʻau, analgesics - "Analgin", "Ketorol", "Promedol".

ʻO ka oxygenation Hyperbaric kahi ala lapaʻau physiotherapeutic e hāʻawi ana i ka oxygenation koko a me kona komo i loko o ka lolo ʻike ʻia. Pau ka mea maʻi ma kahi lumi a me ka hanu i ka oxygen hemolele. Hoʻopau ka Hyperbaric oxygenation i ka hōʻaiʻē o ka oxygen i nā kiko a hoʻihoʻi i ka glycolysis aerobic. Mālama kēia kaʻina hana i ka maikaʻi o ke ola o nā maʻi, e hōʻemi i nā hōʻailona o ka patology a pale i ka hoʻomohala ʻana o nā hoʻopiʻi koʻikoʻi.

Hana hoʻomaʻamaʻa

ʻO nā hiʻohiʻona paʻakikī o ka pathology, maikaʻi ʻoluʻolu i ka hoʻoponopono ʻana i ka lāʻau lapaʻau, pono i ka wawa ʻana. Hoʻokuʻu ʻia nā mea maʻi i nā kīlehe koko a me nā pā pli atherosclerotic mai i nā ʻalā, hoʻonui i ka lumen o nā moku e hoʻohana ana i ka catheter a me ka baluna, a ua hoʻokomo ʻia nā stents i loko o nā ʻalike e mālama ai i ka lumen o ka moku e wehe.

ʻO nā maʻi cerebrovascular e pili i ka mālama ʻana i nā maʻi maʻi: aneurysms arterial a me nā hemorrhages intracerebral.

ʻO ka lāʻau lapaʻau

ʻO ka lāʻau lapaʻau maʻamau maʻamau i hoʻohanaʻia i ka mālama ʻana i nā maʻi cerebrovascular:

  • Hoʻomaloʻo ke aʻa peony i ka ʻāina a ninini me ka wai anuanu. E hoʻomoʻa i ka hoʻopauʻana no hoʻokahi hola, e kānana a lawe i nā manawa 5 i hoʻokahi lā no ka papa ʻaina.
  • I loko o kahi mīʻai kime, ua huki nā 2 mau huaʻai a me 2 mau lemona, ua hui ʻia ke kō me ka meli wai a hoʻōwili ʻia. E hoʻomoʻa i kahi lā maloʻo, a laila lawe i kahi papaʻa 3 mau manawa i ka lā.
  • E ninini ʻia nā paila Pine me ka wai e hoʻolapalapa ana, hoʻomoʻi a hoʻohui i ka wai o ka hapalua o ka lemon i ka waiū. Lawe i ka lāʻau lapaʻau ma kahi ʻōpū ʻole i 3 mau mahina.
  • Lawe ʻia ka ʻōpio Celandine ma kahi ʻōpū ʻole i ʻekolu mau manawa i ka lā no nā wiki 2.

ʻO ka lāʻau lapaʻau kuʻuna kahi maikaʻi maikaʻi i ka hoʻouluulu maʻamau o ka pathology.

Hōʻalo a me ka prognosis

ʻO nā hana e pale ai i ka hoʻomohala ʻana o nā maʻi cerebrovascular:

  1. Ka hopena o ke kahe koko
  2. Hoʻomā hoʻomaʻamaʻa kūlou i nā ala e hiki ai
  3. E hakakā ana i nā hana maikaʻi
  4. Hoʻomaʻamaʻa māmā
  5. ʻO kaʻai kūpono
  6. ʻO ka Optimization o ka hana a me ka hoʻomaha
  7. Ke hoʻoponopono kūpono.

No nā pahuhopu prophylactic, ua kuhikuhi ʻia nā mea maʻi e hoʻomaikaʻi i ke kaila cerebral a hoʻopaʻa i ka ʻaila koko.

Inā mālama koke ʻia ka maʻi a me ka pololei, hiki wale nō ke hoʻomaikaʻi i ke ʻano o ke kanaka maʻi, akā e hōʻemi hoʻi i nā hōʻeha o nā hōʻeha a me nā hōʻeha koʻikoʻi.

Waiho I Kou ManaʻO HoʻOpuka