He aha ka Siofor i lawe ʻia a me ke ʻano o kēia ʻano mea lapaʻau: ka ʻano o ka hana, ka hoʻokuʻu a me ka dosis

Ka puka ʻana - nā papaʻi keʻokeʻo keʻokeʻo:

• Siofor 500: mau pōʻai, biconvex (10 nā pcs. I nā poli, ma kahi kāwele kāleka o 3, 6 a i ʻole 12)
• Siofor 850: oblong, me kahi poki pālua ʻelua (15 pcs. In blisters, in a cardble of 2, 4 or 8 blisters),
• Siofor 1000: oblong, me kahi kiʻahi ma kekahi ʻaoʻao a me ka pā ʻana o ke ʻano "snap-tab" ʻano ʻē aʻe ma kekahi ʻaoʻao (15 mau p. In blisters, in a cardboard bundle o 2, 4 a 8 paha blisters).

ʻO ka mea ikaika o ka lāʻau lapaʻau ka metformin hydrochloride, i loko o hoʻokahi papa he 500 mg (Siofor 500), 850 mg (Siofor 850) a i ʻole o 1000 mg (Siofor 1000).

• Nā mea kūlike: povidone, hypromellose, magnesium stearate,
• Hōʻike Shell: macrogol 6000, hypromellose, titanium dioxide (E171).

Nā hōʻailona no ka hoʻohana ʻana

Kuhi ʻia ʻo Siofor no ka mālama ʻana o ka mellitus type II i ke ʻano, ka mea keu ma nā mea maʻi momona me ka hana ole a me ka hoʻomaʻamaʻa ʻai.

Hiki ke hoʻohana ia e like me ka lāʻau hoʻokahi a i ʻole kekahi mea o ka hōʻiliʻili o ka hui i hui pū me ka insulin a me nā mea āpau hypoglycemic waha.

ʻLoe a me ke kākele

Pono ka lālama e lawe ʻia i ka lāʻau i ka wā o ka pāʻina a i ʻole lā ma hope.

Hoʻoholo ʻia ka nui o ka dosage a me ka lōʻihi o ka mālama ʻana e ke kauka ma muli o ke kiʻekiʻe o ka glucose i ke koko.

Ke lawe nei i ka monotherapy, e kau ʻia nā pākeke 500 mg 1-2 mau manawa i kahi lā a i ʻole 850 mg 1 mau lā i ka lā. Ma hope o nā lā 10-15, inā pono, e hoʻonui mālie ka nui o kēlā me kēia lā i nā papa 3-4 Siofor 500, 2-3 papa Siofor 850 mg a me 2 mau papa Siofor 1000.

ʻO ka nui loa o kēlā me kēia lā he 3000 mg (6 mau papa o 500 mg a i ʻole 3 papa o 1000 mg) ma 3 mau puʻupuʻu i hoʻokaʻawale ʻia.

I ka koho ʻana i nāosa kiʻekiʻe, hiki ke hoʻololi ʻia nā papa ʻelua o Siofor 500 me 1 papa o Siofor 1000.

Inā hoʻoneʻe ʻia ka mea maʻi i ka metformin mai nā lāʻau lapaʻau antidiabetic ʻē aʻe, ke kinai ʻia ka hope a hoʻomaka lākou e lawe iā Siofor i nā palapala aʻe.

I ka hui pū me ka insulin (e hoʻomaikaʻi i ka mālama glycemic), ua kuhikuhi ʻia ʻo Siofor 500 mg 1-2 mau manawa i ka lā a i ʻole 850 mg hoʻokahi manawa i ka lā. Inā pono, hoʻokahi manawa i ka hebedoma e hoʻonui iki ʻia ka nui o nā papa he 3-4 Siofor 500, 2-3 papa Siofor 850 a me 2 mau papa Siofor 1000. Hoʻoholo ʻia ka nui o ka insulin e like me ka pae o ka glucose i ke koko. ʻO ka nui loa o nā lā ma kēlā me kēia lā he 3000 mg i 3 mau puʻupuʻu i hoʻokaʻawale ʻia.

Ke koho nei i kahi maʻa, ua noʻonoʻo nā mea maʻi i ka paʻa ʻana o ka creatinine i loko o ke koko koko. I ka wā e pono ai, pono e nānā ʻia ka loiloi maʻamau o ka hana iā ia.

ʻO nā keiki he 10-18 mau makahiki a no ka monotherapy, a me ka hoʻohui pū ʻana me ka insulin, ma ka hoʻomaka ʻana o ka lāʻau lapaʻau e kuhikuhi ana i 500 mg a i ʻole 850 mg o ka metformin 1 ka manawa i kēlā me kēia lā. Inā pono, ma hope o nā lā 10-15, e hoʻonui mālie ka lāʻau. ʻO ka palena loa o kēlā me kēia lā he 2000 mg (4 mau papa o 500 mg a i ʻole 2 mau papa o 1000 mg) i nā 2-3.

Hoʻoholo ʻia ka nui o ka insulin e like me ka pae o ka glucose i ke koko.

Nā hopena hopena

• He ʻano hopena: ʻano paʻakikī - urticaria, itching, hyperemia,
• Pūnaehana maʻi: pinepine - ʻono ka hoʻoweliweli,
• Liver and biliary tract: hōʻike kūʻokoʻa - kahi hoʻi hou i ka hana o ka transaminases hepatic, hepatitis (hala ma hope o ka hōʻemi ʻana i ka lāʻau),
• Metabolism: līpoki loa - ka lactic acidosis, me ka hoʻohana lōʻihi - ke hoʻemi ʻana i ke kao o ka vitamin B₁₂ a me ka hoʻokaʻawale ʻana o kona ʻike i ka plasma koko (e pono ai i ke ʻano o kēia ʻano ke hana i ka wā e kuhikuhi ana i ka lāʻau i nā mea maʻi me ka megaloblastic anemia),
• Pūnaehana Digestive: nele o kaʻai ʻana, ka ʻaha metallic i loko o ka waha, nilo, ka luaʻi, ka ʻōpū o ka ʻōpū, ʻeha. Hōʻike pinepine kēia mau hōʻailona i ka hoʻomaka ʻana o ka mālama ʻana a maʻamau e haʻalele iā lākou iho. I mea e pale aku ai iā lākou, pono e hoʻonui i ka palaha i kēlā me kēia lā, hoʻokaʻawale ia mea i 2-3 mau pona, a lawe i ka lāʻau lapaʻau me ka meaʻai a i ʻole ma hope o ka pau.

Nā ʻōlelo kikoʻī

ʻAʻole hoʻololi ʻo Siofor i ka meaʻai meaʻai a me ka papa hana i kēlā me kēia lā - ʻo kēia mau ʻano lāʻau lapaʻau e pono ke hui pū me ka lāʻau lapaʻau e like me nā ʻōlelo a ke kauka. Pono nā maʻi āpau e mālama i kahi papaʻai me ka hoʻokeo kūʻokoʻa o ka mau huama i ka lā a pau, a ʻo ka poʻe me ka momona nui e loaʻa kahiʻai haʻahaʻa.

Inā kānalua ʻoe i ka hoʻomohalaʻana o ka waikawa lactic, hoʻihoʻi koke i ka lāʻau a me ka hōʻola o ka haukapila e pono ai.

Hoʻopili ʻia ka Metformin e nā keiki, no laila ma mua o ka hoʻomaka ʻana i ka mālama ʻana a ma ka hana maʻamau i kāna kaʻina, pono ke hoʻoholo ʻia ka ʻike ʻana o ka creatinine i ka plasma koko. Ka mea kia nui o ka nānā ʻana inā inā he pilikia o nā hana renal impaired, no ka laʻana, i ka hoʻomaka ʻana o ka hoʻohana ʻana o nā diuretics, non-steroidal anti-inflammatory a antihypertensive o nā lāʻau lapaʻau.

Inā pono e hoʻokō i kahi loiloi X-ray me ka hoʻokō intravenous o kahi mea kū like iodine e pehu ana, ʻo Siofor i kahi manawa iki (48 mau hola ma mua a he 48 mau hola ma hope o ke kaʻina hana) pono e hoʻololi ʻia i kekahi lāʻau lapaʻau hypoglycemic ʻē aʻe. Pēlā nō e hana ʻia i ka wā ke kuhikuhi ana i kahi hana ʻoki ʻana i hoʻolālā ʻia ma lalo o ka anesthesia laulā, me ka maʻi hōʻehu a i ʻole ka spinal anesthesia.

Wahi a nā hoʻokolohua lapaʻau hoʻokahi mau makahiki, ʻaʻole i pili ka metformin i ka ulu, ulu, a me ka puberty o nā keiki. Eia naʻe, ʻaʻohe mea e pili ana i kēia mau kuhikuhi me ka lōʻihi o ka lāʻau, no laila, nā keiki e loaʻa ʻo Siofor, ka mea nui i ka manawa prepubertal (10-12 mau makahiki), pono ke nānā.

ʻAʻole alakaʻi ʻo Monotherapy me Siofor i ka hypoglycemia. Me ka hui pū ʻana (me ka hui pū me ka lālani a i ʻole ka lālani sulfonylurea) aia kahi manawa kūpono, no laila, pono e hoʻomaʻemaʻe ʻia.

Siofor, i hoʻohana ʻia me he lāʻau lā hoʻokahi, ʻaʻole ia e hoʻopilikia i ka wikiwiki o nā hopena a me / a i ʻole hiki ke hoʻopaʻa ʻia. Ke hoʻohana nei i ka metformin ma ke ʻano he lāʻau paʻakikī, aia kekahi pilikia e pili ana i ka hoʻomohala ʻana i nā kūlana hypoglycemic, no laila, e mālama pono ka akahele i ka wā e komo ai i kekahi mau hana pōʻino, e komo pū ai i ka wā e hoʻokele ana i nā kaʻa.

Hoʻohui nūhou

Hoʻohālikelike ka metformin i ka wā o nā noiʻi me ka hoʻokele intravascular o nā iodine e loaʻa i nā mea kūlike.

ʻAʻole ia e inu i ka inu ʻawaʻawa a lawe i ka lāʻau lapaʻau e loaʻa ana i ka ethanol i ka wā mālama, ʻoiai ka ulu ʻana o ka hoʻomohala ʻana i ka acidosis lactic, ʻoi aku paha me ka hana ʻana o ka naʻau, pōʻaiʻai aʻai ʻole paha.

ʻO nā hui e koi ana i ka akahele e pili ana i nā hopena pili e hiki ke hoʻopili:

• Danazole - ka uluʻana o kahi hopena hyperglycemic,
• ʻO Angiotensin-hoʻohuli i ka hoʻohui o ka enzyme a me nā lāʻau antihypertensive ʻē aʻe - e hoʻohaʻahaʻa ana i ke koko glucose,
• ʻO nā hormone thyroid, nā hana hoʻohālikelike i ka waha, ka waikeka nicotinic, glucagon, epinephrine, derivatives phenothiazine - he hoʻonui i ka hoʻoliʻi o ka toto koko,
• Nifedipine - hoʻonui i ka hoʻohuihui a me ka piʻi nui o ka metformin i ke koko koko, ka lōʻihi o kona excretion,
• Cimetidine - e hoʻolohi ana i ka kinai o nā metformin, e hoʻonui ana i ka ulu o ka losisic acidosis,
• Salicylates, derivatives sulfonylurea, insulin, acarbose - hoʻonui hua hypoglycemic,
• ʻO nā hua lāʻau cationic (procainamide, morphine, quinidine, triamteren, ranitidine, vancomycin, amiloride) i hūnā ʻia i loko o nā ʻōpala - kahi mahuahua o ka piʻi loa o ka metformin i loko o ke koko koko.
• Furosemide - kahi hāʻule i kona kaohi a me ka hapa-ola,
• Pākuʻi i nā anticoagulants - nāwaliwali o kā lākou hana
• Agonists Beta-adrenergic, diuretics, glucocorticoids (no ka hoʻohana ʻana i ka systemic a me ka topical) - kahi mahuahua o ke kahe o ke koko.