ʻIoplelo Angiopril

Inoa inoa honua - pio

Ka hoʻonohonoho ʻana a me ke ʻano o ka hoʻokuʻu ʻana. ʻO ka mea waiwai he captopril. Nā ʻ 0.0lelo 0.025 a me 0,05 g, 10 mau pā. i ka moena.

ʻO ka hoʻohana ʻana o ka angiopril lapaʻau wale nō e like me ka mea i kuhikuhi ʻia e ke kauka, ua hāʻawi ʻia ka wehewehe no ke kuhikuhi!

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ʻO nā waiwai Pharmacological

Antihypertensive, vasodilator, cardioprotective, natriuretic. Mālama ia i ka ACE, pale i ka nalo o ka angiotensin I ka angiotensin II a pale i ka hana ʻole ʻana o nā vasodilators endogenous. Hōʻike ʻia ka hopena antihypertensive 15-60 mau minuke ma hope o ka lawelawe waha, a hiki i ka lōʻihi ma hope o 60-90 mau minuke a mau loa i nā hola 6-12. He hōʻemi ia i ka manawa o ka puʻuwai, mua a ma hope o ka hopohopo, ka puʻuwai ma ke kaʻe pulmonary a me ke kūʻē o nā moku pulmonary, hoʻonui i ka hopena cardiac (HR) ʻaʻole e loli). Loaʻa kahi hopena cardioprotective. Hoʻopili koke a hoʻopaʻa ʻia mai ka pānaʻi ʻana. Hoʻonui ka hoʻohana Sublingual i ka bioavailability a hoʻomaikaʻi i ka hoʻomaka ʻana o ka hana. Loaʻa ia i nā pale o ka histohematological, ʻaʻole i waiho i ka BBB, ma ka pleka a hele i ka waiū umauma. ʻO ka hoʻopauʻana hapalua-ola e hana i 2-3 mau hola. Hoʻopau nui ʻia e nā ʻōpū.

Nā hōʻailona no ka hoʻohana ʻana

Hoʻokomo ʻia me Arterial hypertension, ʻo ia hoʻi renovascular (akahiki a maʻalahi paha e like me ka lālani mua i koho ʻia, ʻeha inā he maikaʻi ʻole a ʻohiʻohi ʻole ʻia ke ʻano maʻamau), CHF (i loko o ke ʻano hui ʻana), Lf dysfunction ma hope o kahi infococodio myocardial i loko o kahi kūlana paʻa, maʻi nephropathy diabetes me ka type 2 diabetes mellitus 1 (me albuminuria ma mua o 30 mg / lā).

Nā Hoʻohui

Hypersensitivity e captopril a i ʻole nā ​​mea ʻē aʻe o ka ACE, hapai, lactation (ma Rūsia, ʻaʻole ʻae ʻia ka lāʻau lapaʻau no ka hoʻohana ʻana i nā poʻe ma lalo o ka 18 mau makahiki o ka makahiki.) Polokalamu. ʻO ka mōʻaukala o ka angioedema i ka wā o ka mālama ʻana me ka ACE inhibitors, ka pakanui a i ʻole idiopathic angioedema, stenosis aortic, cerebrovascular a me nā maʻi maʻi (e pili ana i ka cerebrovascular insufficiency, coronary heart heart, coronary insufficiency), nā maʻi autoimmune o ke kiko konumele ( SLE, scleroderma), pale ʻana i ka hematopoiesis pumehana o ka iwi, lālani mellitus, hyperkalemia, bilateral renal aren stenosis, stenosis o hoʻokahi hāneʻalā pēpē, ke ʻano ma hope o ka hoʻololi ʻana o ka maʻi, ʻoi a me / a i ʻole ka hemahema o ka leʻaleʻa, he meaʻai me kahi paʻa o Na +, nā kūlana i hele pū me ka emi ʻana o BCC (me ka maʻi ʻaʻala, hoʻohuka), ʻoi loa ka makahiki.

Pehea e hoʻohana ai: dosis a me ke ʻano o ka mālama ʻana

I loko, i 1 mau hola ma mua o ka papaʻa ʻana, me ka hypertension arterial, hoʻomaka ka mālama ʻana me ka hopena haʻahaʻa haʻahaʻa loa loa i ka nui o 12.5 mg 2 mau manawa i kahi lā (loaʻa ʻole me 6.25 mg 2 mau manawa i ka lā). Pono e uku ʻia i ka ʻomaʻomaʻi o ka hopena mua ma ka hola mua. Inā ulu ka hypotension arterial i kēia hihia, pono ke neʻe ka mea maʻi i kahi kūlana (ʻoi aku ka pane i ka hopena mua ʻaʻole e lilo i mea pale i kēlā lāʻau hou. Me ka monoport captopril, hiki ke loaʻa ka hopena maikaʻi ma ka manawa like i ka hoʻopiha ʻana i ka hoʻokomo o Na + i ke kino.

Me kahi papa o ka hoʻōla, ka hopena, inā pono, e hoʻonui ʻia ma hope o 2-4 mau pule, e like me ka mea hiki - a hiki i 50 mg 3 mau manawa i ka lā. Ma ka maʻi hypertension arterial (diastolic blood pressure of 115 mm Hg a i ʻole ke kiʻekiʻe), hui pinepine ʻia me nā lāʻau antihypertensive ʻē aʻe, ʻoi aku ka nui o nā diuretics thiazide (hydrochlorothiazide - 25-50 mg / lā). Hiki ke hoʻonui ʻia ka nui diuretic me kahi manawa o 1-2 mau wiki a hiki i ka nui o ke ana nui e hoʻohana ai i ka mālamaʻana i ka maʻi hypertension.

ʻO ka papa mālama mālama no ka "māmā" a me ka maʻi hypertension arterial (diastolic blood pressure - 95-114 mm Hg) ka 25 mg (i kekahi mau manawa 12,5 mg) mau manawa i ka lā.

I nā poʻe maʻi ʻelemakule, ʻo ka hopena mua loa he 6.25 mg 2 mau manawa i ka lā.

I ka hihia o ka naʻau puʻuwai, ua kuhikuhi pū ʻia me ka diuretics a me / a i hui pū ʻia me ka hoʻomākaukau digitalis (i mea e pale ʻole ai ka nui o ka neʻe ʻana i ke kahe o ke koko ma mua o ka hoʻokō ʻana o ka captopril, hoʻoneʻe ʻia ka diuretic a i hōʻemi ʻia ka hopena). ʻO ka dosis mua he 6.25 mg a i ka 12.5 mg 3 mau manawa i ka lā, inā pono, e hoʻonui i ka dosis i 25 mg 3 mau manawa i ka lā. ʻO ka dosis kiʻekiʻe loa ʻo kēlā me kēia lā he 150 mg.

Ma ka hihia o ka hana LV i hala mahope o ka loaʻa ʻana o kahi infococote myocardial i loko o nā mea maʻi ma kahi kūlana haukapila, hiki i ka captopril ke hoʻomaka i ka manawa like me 3 lā ma hope o ka myocardial infarction. ʻO ka dosis mua he 6.25 mg / lā, a laila hiki ke hoʻonui ʻia ka nui o kēlā me kēia lā i ka 37.5-75 mg ma 2-3 mau pona (e like me ka hoʻomanawanui ʻana o ka lāʻau) a hiki i ke kiʻekiʻe o 150 mg / lā.

Me ka hoʻolālāʻana o ka hypotension arterial, pono paha kahi hōʻemi. ʻO nā ho'āʻo ʻana e hoʻohana i ka nui o kēlā me kēia lā ma kahi o 150 mg e pono ke kau ʻia ma ka hoʻomanawanui captopril.

I ka nephropathy maʻi, ua kuhikuhi ʻia kahi nui o 75-150 mg / lā.

Me ka haʻahaʻa haʻahaʻa o ka hana renal i ʻole ke kau (CC ma ka liʻiliʻi he 30 ml / min / 1.73 sq.m), hiki ke kuhikuhi ʻia ka captopril ma kahi maʻi ʻo 75-100 mg / lā. Me ka nui o ka ʻōlelo o ka renal dysfunction (CC ma mua o 30 ml / min / 1,73 m), pono ka nui o ka lāʻau ma mua o 12.5 mg / lā, laila inā pono, e hoʻonui iki ʻia ka nui o ka captopril ma luna o nā lōʻihi o ka manawa. ma ka hihia o ka lapaau ana o ka hypertension arterial, i kela la i keia la.

ʻAʻole ʻae ʻia nā keiki (ma Lūkia ke hoʻohana ʻia ʻana i nā keiki) no ka hypertension arterial koʻikoʻi (me ka hana ʻole o nā lāʻau ʻē aʻe) ma kahi pāʻālua o 0.1-0.4 mg / kg 2 mau manawa i ka lā.

ʻO nā pēpē - kahi hua mua o 0.01 mg / kg 2-3 mau manawa i ka lā, nā keiki kahiko - ke kau mua ʻana o ka 0.3 mg / kg 3 mau manawa i ka lā, inā pono, e hoʻonui i ka ʻai ma ka 0.3 mg / kg ma waena o nā hola 8-24 i ka hopena haʻahaʻa o ka liʻiliʻi . ^ E Ha yM.

Ka hana lāʻau lapaʻau

ACE paleʻai. Hoʻopili i ka hoʻokumuʻana o ka angiotensin II mai angiotensin I. ʻO kahi hōʻemi i loko o nā kiko o ka angiotensin II alakaʻi i kahi hoʻohemo pololei i ka hoʻokuʻu ʻana o ka ald testosterone. I ka manawa like, ua lilo ka OPSS, ke kahe o ke koko, post- a me ka preload ma ka puʻuwai. E hoʻonui i nā arela i ka ʻoi aku ka nui ma mua o nā veins. Hōʻemi ia i ka emi ʻana o ka hōʻemi o ka bradykinin (ʻo kekahi o nā hopena o ka ACE) a me ka hoʻonui ʻana o ka hana o Pg.

ʻAʻole paʻa i ka hopena antihypertensive ka hana o ka plasma renin, kahi mākaʻikaʻi i ke koko i ʻike ʻia i ka wā maʻamau a hoʻemi ʻia hoʻi nā mea i hana ʻia o ka hormone, ʻo ia ka hopena i ka pūnaehana renin-angiotensin. Hoʻonui nā coronary a me ke kahe koko.

Me ka hoʻohana mau ʻana, hoʻemi ʻia ka nui o ka hypertrophy o ka myocardium a me nā paia o nā ʻalihi o ke ʻano resistive. Hoʻomaikaʻi i ka hāʻawi ʻana i ke koko i ka myocardium ischemic. Hoʻēmi i ka hoʻohui platelet. Kōkua i ka hoʻemi ʻana i nā ʻikepili Na + i nā maʻi me ka hōʻeha ʻole o ka naʻau.

I nā wai o 50 mg / lā, hōʻike ia i nā waiwai angioprotective e pili ana i nā moku o ka microvasculature a hiki ke hoʻolōʻihi i ka holomua o ka hiki ʻana o ka pilikia renal i ka nephroangiopathy maʻi.

ʻO ka emi ʻana o ke kahe o ke koko, i ka hoʻohālikelike ʻana i nā vasodilators (hydralazine, minoxidil, etc.) ʻaʻole i hele ʻia e ka refach tachycardia a alakaʻi i ka emi ʻana o ka makemake o ka oxygen myocardial. I ka hiki ʻole o ka puʻuwai naʻau i kahi kūpono e pono ai ka hopena o ka piʻi ʻana o ke koko.

ʻO ka emi loa ʻana o ke kahe o ke koko ma hope o ka hoʻokele waha ʻana i nānā ma hope o 60-90 mau minuke. ʻO ka lōʻihi o ka hopena hypotensive e hilinaʻi ana i ka dosis a hiki i nā waiwai loea i loko o kekahi mau pule.

Nā hopena hopena

Mai ka CCC: tachycardia, hoʻemi i ke koko, a me ka hypthension orthostatic.

Mai ka pūnaehana hoʻonāukiuki: dizziness, headache, ʻehaʻeha, asthenia, paresthesia.

Mai ka urinary system: proteinuria, hana renal impaired (hoʻonui i ka urea a me ka mea hana i loko o ke koko).

Mai ka ʻaoʻao o ka wai-electrolyte metabolism: hyperkalemia, acidosis.

Mai nā kino hemopoietic: neutropenia, anemia, thrombocytopenia, agranulocytosis.

Nā kūmole pale: angioedema, ka holo o ke koko i ka ʻili o ka maka, ke ʻano, ka ʻeha, ka ʻāʻī o ke kino (maculopapular, ʻaʻole pinepine i ka vesicular a i ʻole bullous), kaʻeha, photosensitivity, bronchospasm, maʻi serum, lymphadenopathy, i nā hihia loaʻa, ka helehelena o nā antinuclear antibodies i ke koko.

Mai ka papa hana ʻana: ka hoʻohaʻahaʻa ʻana i ka momona, hoʻemi ʻia ka makemake, stomatitis, hōʻailona dyspeptic, nausea, ʻeha o ka ʻōpū, constipation a i ʻole ʻūhā, hoʻonui i ka hana o ka transaminases hepatic, hyperbilirubinemia, nā hōʻailona o ka maʻi hepatocellular (hepatitis) a me cholestasis (ma nā hihia loaʻa ʻole). pancreatitis (ma nā hihia kaʻawale).

ʻO kekahi: ʻōpala "" maloʻo ", hala ma hope o ka hoʻokuʻu ʻana o ka lāʻau, asthenia, ʻūhā o nā wāwae. Nā hōʻailona: kahi hōʻailona i hoʻokahe ʻia i ke koko, a hiki i ka wāwahi, myocardial infarction, pilikia cerebrovascular maʻi, nā hoʻonā thromboembolic.

Hoʻomaʻamaʻa: kau i ka mea maʻi me ka hoʻohaʻahaʻa i lalo o nā wāwae haʻahaʻa, nā ana e hoʻihoʻi i ka hoʻihoʻi ʻana i ke koko (e hoʻonui i ka BCC, a me ka iv infusion o 0.9% hopena NaCl), ʻo ka hōʻailona lapaʻau. I nā pākeke, hiki ke hemodialysis, hiki ʻole ke ʻano o nā dialy peritoneal.

Nā ʻōlelo kikoʻī

Ma mua o ka hoʻomaka ʻana, me ke ʻano maʻamau i ka wā o ka mālama me ka captopril, pono ke nānā ʻia ka hana o ka pēpē. I ka poʻe maʻi me CHF, hoʻohana ʻia lākou ma lalo o ka mālama kiaʻi lapaʻau.

E kū'ē i ke kāʻei o ka hoʻohana lōʻihi ʻana o ka captopril ma kahi o 20% o nā mea maʻi, aia he ulu mau i ka kaohi ʻana o ka urea a me ka creatinine i ka serum ma mua o 20% i hoʻohālikelike ʻia i ka maʻamau a i ʻole ka waiwai mua. ʻOi aku ma mua o 5% o nā mea maʻi, ʻoi aku ka poʻe me ka nephropathy koʻikoʻi, e koi i ka hōʻemi o ka mālamaʻana ma muli o ka hoʻonui o ka neʻe ʻana o ka maka.

I loko o nā mea maʻi me ka hypertension arterial me captopril, hypotension nui i ʻike ʻia i loko o nā hihia loaʻa ʻole, nui ka hopena o ka ulu ʻana i kēia ʻano me ka nui o ka holo ʻana o ka wai a me nā paʻakai (no ka laʻana, ma hope o ka maʻi kūleʻa me ka diuretics), i nā mea maʻi me ka hoʻopiʻi o ka naʻau a i ʻole ka hana ʻana i ka dialysis.

Hiki ke hōʻemi ʻia ka nui o ke kahe o ke koko i ka hoʻomaka ʻana me ke kāpae ʻana i ka wā mua (4-7 mau lā) o kahi diuretic a i ka hoʻonui ʻana hoʻi o ka hoʻoulu ʻana o NaCl (ma kahi o 1 hebedoma ma mua o ka hoʻomaka ʻana o ka lawelawe), a i ka hoʻopiʻi ʻana i ka captopril i ka hoʻomaka ʻana o ka mālama ʻana i nā dosis liʻiliʻi (6.25-12.5 mg / lā).

I ka wā o ka lāʻau lapaʻau ma ke kumu maʻi outpatient, e hoʻomaopopo i ka mea maʻi e pili ana i ka hiki ʻana mai o nā hōʻailona o ka maʻi, e koi ana i ka hoʻokolokolo olakino e pili pono ana, nā hoʻomaʻamaʻa kaua a me ka lab. I nā mahina 3 mau mua o ka hoʻolālā, ka nānā ʻia o ka nui o ka leukocytes koko i kēlā me kēia mahina (ma aneʻifter - hoʻokahi manawa i kēlā me kēia 3 mau mahina), i nā mea maʻi me nā maʻi autoimmune i nā mahina 3 mua - i kēlā me kēia 2 mau pule, a laila - kēlā me kēia 2 mau mahina. Inā emi mai ka nui o nā leukocytes ma mua o 4 tausani / μl, hōʻike ʻia kahi hōʻike koko ākea, ma lalo o 1 tausani / μl, ua kāohi ʻia ka lāʻau lapaʻau. Inā hele mai ka ʻōmaʻomaʻi mua o ka maʻi lua e pili ana i ka mua o ka myeloid hypoplasia, pono e hana koke i kahi hōʻike hoʻoweliweli kikoʻī.

Pono e hoʻokaʻawale i kahi kūʻokoʻa kūʻokoʻa o ka lāʻau a me kahi hoʻonui kūʻokoʻa kūʻokoʻa i ka ulu o ka hana kino.

I kekahi mau hihia, kūʻē i ke ʻano o ke hoʻohana ʻana o nā inhibce ACE, ʻo ia hoʻi captopril, loaʻa i ka nui o ke neʻe o ka K + i ka serum. Hoʻopilikia ka hopena o ka hoʻomohala ʻana i ka hyperkalemia me ka hoʻohana ʻana o nā inhibitor ACE i ka poʻe maʻi me ka maikaʻi ʻole a me ka diabetes mellitus, a me nā mea e lawe nei i ka diuretics potassium-sparing, K + nā lāʻau a me nā lāʻau ʻē aʻe e hoʻoulu ai i ka piʻi ʻana o ka ʻohi o K + i ke koko (no ka laʻana heparin). ʻO ka hoʻohana like ʻana o ka diuretics potassium-sparing a me K + e hoʻomākaukau ai e pale.

Ke lawe nei i ka hemodialysis i nā maʻi e loaʻa ana i ka captopril, e pono ke pale ʻia ka hoʻohana ʻana o ka dimesis dialysis kiʻekiʻe (e.g. AN69), i ia mau mea, e hoʻomāhuahua ʻia ka hopena o ka ulu ʻana o ka hopena anaphylactoid.

I ka hihia o ka hoʻomohala ʻana o ka angioedema, ua hoʻopau ʻia ka lāʻau lapaʻau a nānā pono ʻia ke nānā ʻana i ka lāʻau lapaʻau a me ka hōʻailona hōʻailona.

Ke lawe nei i ka captopril, hiki ke ʻike ʻia kahi hopena kūpono ʻole i ka wā e ʻimi ana i ka urine no ka acetone.

ʻO nā mea maʻi ma ka liʻiliʻi o ka paʻakai a i ʻole ka paʻakai ka paʻakai ka nui o ka nui o ke kahe nui ʻana i ke kahe o ke koko a me ka hoʻomohala ʻana i ka hyperkalemia.

I ka wā o ka mālama ʻana, pono e mālama ʻia i ka wā e alakaʻi ana i nā kaʻa a komo i nā hana ʻē aʻe ʻē aʻe e koi ai i ka piʻi nui o ka neʻe a me ka wikiwiki o ka hopena psychomotor (maʻi paha, hiki i ke kauā ma mua o ka hopena).

Hoʻohui

Hoʻonui i ka neʻe o ka digoxin i loko o ka plasma e 15-20%.

ʻO Cimetidine, e hoʻolohi ana i ka metabolism ma loko o ke ake, hoʻonui i ke kao o ka captopril i ka plasma.

Ua nāwaliwali ka hopena antihypertensive e nā NSAIDs (ka hoʻomau ʻana o Na + a ua hōʻemi iho i ka synthesis Pg), inā ua kū'ē loa i ke ʻano o ke kumu o ka renin haʻahaʻa, a me ka estrogens (Na + lohi).

ʻO ka hui pū me nā diuret thiazide, vasodilators (minoxidil), verapamil, beta-blockers, tricyclic antidepressants, ethanol hoʻonui i ka hopena hypotensive.

Hoʻohui me ka hoʻohana ʻana me ka diuretics pākōlani-Karing, ka mākaukau K, ka cyclosporine, haʻahaʻa Na + wai (e piha ana i ka K + a hiki i 60 mmol / l), nā mea hoʻohui me nā pākaha, nā mea paʻakai (ka nui o nā nui o K +) e hoʻonui i ka hōʻeha o ka hyperkalemia.

Hoʻololi i ka hoʻopuka ʻana o Li + nā lāʻau lapaʻau.

Hoʻopili ʻo Clonidine i ka uluʻana o ka hopena hypotensive.

Me ka koho i ka captopril ke lawe ʻana i ka allopurinol a i ka procainamide paha, piʻi nui ka pilikia o ka hoʻomohala ʻana i ka maʻi Stevens-Johnson a me ka hana immunosuppressive.

ʻO ka hoʻohana ʻana o ka captopril i nā maʻi e loaʻa ana i ka immunosuppressants (e.g. azathioprine a i ʻole ka cyclophosphamide) e hoʻonui i ka pilikia o ka hoʻomohala ʻana i nā maʻi hematologic.

E makaʻala no ka hoʻohana

Hoʻolaha ʻia ka hana ma lalo o ka mālama mālama olakino maʻamau. I ka wā o ka mālamaʻana, ka nānā ʻana o ke kahe o ke koko, nā hiʻohiʻona o ke koko peripheral, ka nui o ka protein, potassium potassium, urea nitrogen, creatinine, hana o ka pēpē, ka nui o ke kino, a me ka ʻai e pono ai. Me ka hoʻouluʻana o ka hyponatremia, pāʻai, ke hoʻoponopono ʻana i ka hoʻoponopono ʻia dosage e pono ai. Pono ʻia ka mālama ʻana i ka wā e hoʻokō ai i nā hōʻiliʻili o nā maʻi (me ka nānā pūpū), ʻoi loa ke hoʻohana ʻana i ka anesthetics ākea i loaʻa he hopena hypotensive. Hōʻike ʻia e haʻalele i ka hoʻohana ʻana i nā mea inu wai i ka wā o ka mālama ʻana. E hoʻohana me ka akahele aʻo ka hana ʻana no nā mea hoʻokele o nā kaʻa a me nā poʻe e pili pū ana i ka hoʻoulu ʻana o ka makaʻala. Inā kapili ʻia ka makeʻe, ʻaʻole e pāpālua ʻia ka hopena ma hope. Ke hoʻokō nei i kahi hoʻokolohua no ka acetonuria, he hopena maikaʻi.

Nā hopena hopena

Mai ka ʻaoʻao o ka pīnaehana nūna a me nā unuhi naʻau: nā luhi, hoʻoweliweli, ka ʻeha, ke kaumaha o ka pūnaehana nū o ke kikowaena, ka hiamoe, ke hoʻohālikelike, ke kaumaha, lokoxia, nā kīwaha, ʻāʻī a i ʻole nā ​​puʻupuʻu ʻana i nā hiʻona, ʻike maka a me ka honi paha. Mai ka pūnaehana cardiovascular a me ke koko (hematopoiesis, hemostasis): hypotension, komo orthostatic, angina pectoris, myocardial infarction, cardiac arrhythmias (atrial tachy a bradycardia, atrial fibrillation), palpitations, ʻeha cerebrovascular accident, peripheral edema, lymphadenopathy, anemia, pain pain, pulmonary embolism, pulmonary embolism, pulmonary me nā hana renal impaired, kūʻē i ke kūkaʻi o nā collagenoses), thrombocytopenia, eosinophilia. Mai ka papa hana hanu: bronchospasm, pōkole o ka hanu, interstitial pneumonitis, bronchitis, huaʻai maloʻo pono ʻole. Mai ka hana hanu: anorexia, ʻeha ʻono, stomatitis, lesi ulcerative o ka mucous membrane o ka waha waha a me ka ʻōpū, xerostomia, glossitis, pilikia paʻakikī, ʻāhaʻi, luaʻi, dyspepsia, lemulō, ʻeha o ka ʻōpū, constipation a ʻeha ʻole, pancreatitis, hōʻeha kino (cholestasis , hepatitis cholestatic, hepatocellular necrosis). Mai ka pūnaehana genitourinary: function renal impaired, oliguria, proteinuria, impotence. Mai ka ʻili: ʻulaʻula o ka maka, wikiwiki, ʻeha, dermatitis exfoliative, necrolysis epidermal, pemphigus, herpes zoster, alopecia, photodermatitis. Nā maʻi alerine: ʻO ka maʻi Stevens-Johnson, ka urticaria, ka edema Quincke, ka pīhoihoi anaphylactic, a me nā mea ʻē aʻe: ke kuni, ka hiʻi ʻana, sepsis, arthralgia, hyperkalemia, gynecomastia, maʻi serum, hoʻonui i ke koko o ka enzim enzim, urea nitrogen, acidosis, maikaʻi ke kūleʻa ʻana i ka wā e hoʻāʻo ai i ka antibodies i kekahi antigen nukle

ʻLoe a me ke kākele

I loko, 1 hola ma mua o ka papa ʻaina. Hoʻonohonoho ʻia ka ʻākena dosage hoʻokahi.

Me ka hypertension arterial - i kahi maʻi ma mua o 25 mg 2 mau manawa i kahi lā. Inā kūpono, e lūlū ka hopena (me kahi manawa o nā hebedoma 2-4) a hiki i ka hopena kūpono loa. Me ka hypertension arertial haʻahaʻa a maʻalahi paha, ʻo ka maʻi mālama mālama maʻamau he 25 mg 2 mau manawa i kahi lā. ʻO ka dosis kiʻekiʻe loa he 50 mg 2 mau manawa i ka lā. Ma ka maʻi hypertension arterial, ʻo ka nui loa ka nui o 50 mg 3 mau manawa i ka lā. ʻO ka dosis kiʻekiʻe loa ʻo kēlā me kēia lā he 150 mg.

Ma kahi hikiʻole i ka puʻuwai ulu, ke kauoha ʻia nei ʻo Angiopril i nā hihia kahi i hāʻawi ʻole ʻia ai ka diuretics i kahi hopena kūpono. ʻO ka awelika mālama mālama ʻia he 25 mg 2-3 mau manawa i ka lā. I ka wā e hiki mai ana, inā pono, e hoʻonui i ka dosis (me kahi keke o nā liʻiliʻi 2 mau pule). ʻO ka dosis kiʻekiʻe loa ʻo kēlā me kēia lā he 150 mg.

No ka poʻe maʻi me kahi pae haʻahaʻa kūpono o ka hana ʻole o ka pilikia (Cl creatinine ma kahi o 30 ml / min), hiki ke kuhikuhi ʻia ʻo Angiopril i kahi maʻi o 75-100 mg / lā. Me kahi kekee i ʻōlelo ʻia i nā hana hoʻololi ʻole āpau (Cl creatinine ® -25

Mai mālama i nā keiki.

Inoa Kūʻai ʻole honua

ʻO ka inoa inoa ʻole honua no ka huahana ʻo Captopril.

No kā lākou mālamaʻana i nā kahe koko, pono ke koi ʻia ʻo ka lāʻau paʻakikī, ka mea e komo ai i nā lāʻau lapaʻau, kahi me ka angiopril.

Ke loaʻa nei ka lāʻau lapaʻau i kēia code ATX: C09AA01.

E hoʻokuʻu i nā palapala a me ka ʻano

Hoʻokuʻu ʻia ka hoʻokuʻu ʻia o ka lāʻau i ke ʻano o nā papa i kau ʻia ma nā kaha o 10 mau pcs a me 4 pcs. Aia ka pūpū pepa paha i ka 1, 3, 10 mau kaha o 10 mau papa i hoʻokahi a i ʻole 1 mau ʻāpana me 4 papa. ʻO ka mea hana ikaika e captopril - 25 mg. Eia kekahi, ʻo ka stearic acid, lactose, mais starch, colloidal silicon dioxide a me ka microcrystalline cellulose e hoʻohana.

Lapaʻau lāʻau

Ma hope o ka lawe ʻana i nā papa, ua hopu koke ʻia i ka gastrointestinal tract ma muli o ka bioavailability o 60-70%. Hōʻailona kahi hoʻolalelima me ka hoʻohana pinepine ʻana o ka captopril me ka meaʻai. ʻO ka hapalua o ka ola o ka lāʻau lapaʻau e lawe i nā hola 2-3. ʻO ka hapalua o ka papa hana i excreted i loko o ka urine i kahi loli ʻole.

Me ka maʻi diabetes

Inā loaʻa i ka mea maʻi nephropathy maʻi, a laila loaʻa ka lāʻau lapaʻau ma 75-150 mg i kēlā me kēia lā. Hiki ke loli ʻia ka Dosage e kou mea mālama olakino.

Inā loaʻa i ka mea maʻi nephropathy maʻi, a laila loaʻa ka lāʻau lapaʻau ma 75-150 mg i kēlā me kēia lā.

Ke noi no ka hana lawelawe lēʻaleʻa

Me ka mālama pono a ma lalo o ka mālama ʻana i ka lāʻau lapaʻau, lawe lākou i ka lāʻau lapaʻau no nā pilikia o ke ake.

Hoʻolaha ka waipuna

I ka wā mālama, pāpā ʻia ka inu ʻawaʻī. ʻO kā lākou pilina me ka hana ikaika e hiki ke hana i ka hypertension hoʻomau.

I ka wā mālama, pāpā ʻia ka inu ʻawaʻī.

Inā kūpono, ua hoʻololi ʻia ka lāʻau e ke ʻano. I waena o lākou:

Pono e hoʻololi ʻia nā loli e nā kauka e koho i ka lāʻau lapaʻau e noʻonoʻo ana i nā hiʻohiʻona pilikino o ke kino o ka mea maʻi a me ka hōʻeha o ka pathology.