He aha ka maikaʻi ʻo Omez a i ʻole Pariet me ka pancreatitis?

A eia kuʻu manaʻo e pili ana i kēia mau lāʻau. Hoʻopau kēia mau PPI āpau i ka 100% acid inā lawe ʻia ka 40 mg. A pēlā e koho ai iā lākou. A loaʻa pinepine i ka hapa mau haʻahaʻa. Akā ma kahi hapalua hapalua, e wikiwiki koke a hoʻohemo mau nei i ka acidity, i kekahi manawa wale nō. A no ke aha makaʻu wau i ka weliweli i ka lawe ʻana i nā lāʻau lapaʻau e like me kēia, me aʻu e manaʻo nei, ninini ʻo ia, inā makemake nui, hiki iā ʻoe ke hoʻokaʻawale i ka wai ʻōpū ma luna o kahi ʻano. No laila, lawe au i nā lāʻau lapaʻau ikaika loa: famotidine, ranitidine. Hoʻopilikia lākou no TM, aia nō kahi rebound syndrome i ka wā hiki ke hoʻopau, akā ma aneʻi ... he maoli maoli ia, a ʻōlelo ka PPI ʻaʻole ia. ʻOiai naʻe, ʻaʻole naʻe mai ka cannon i nā manu liʻiliʻi. Hoʻokahi mea i ka pilikia a i ʻole ka papa pōkole. A inā he koʻikoʻi ʻo ka hoʻākāka wai no ka mea ua hoʻonui ʻia ka paʻakai?

Eia, aia kekahi kauoha no nā kauka. E pono ai ka lāʻau lapaʻau, wikiwiki a hana hoʻi .. e like me .. makana .. ʻo ia kaʻu manaʻo, hiki paha i hewa. ʻAʻole pono wau e koi i ka ikaika o kēia kaona ʻaina ʻOiai e kōkua nā lāʻau hōʻemi ikaika.

ʻO nā waiwai Pharmacological

ʻO ka pūnaina o Omez e komo pū me ka omeprazole waiwai, e hōʻemi ana i ka hoʻohālikelike ʻana o ka waikila hydrochloric i loko o ka ʻōpū a hoʻoweliweli i ka maʻi Helicobacter, kahi bacterium e hoʻonāukiuki i ka ulceration. Hoʻohana ka lāʻau i ka lā, ʻo kona bioavailability (pae o ka assimilation) me kahi pākahi hoʻokahi ʻaʻole iʻoi aku ma mua o 40%.
ʻO ka mea kūpono i Pariet he rabeprazole. Mālama pū kekahi i ka hana o nā waikona e nā sela o ke kinapu o loko o ka ʻōpū, akā, ʻaʻole ia e hoʻopilikia i ka Helicobacter. ʻO ka lōʻihi o ka hopena therapeutic o ka rabeprazole hiki ke piʻi i 2 lā, a ʻo 52% ka bioavailability.

ka hele ʻana o nā ʻōpū a me ka ʻānai ʻana i ka ʻōpū a i ʻole ka duodenum, me ke ʻano o ko lākou kumu,
maʻi maʻi refrox gastroesophageal - GERD (hōʻino i ka pā esophagus ma muli o ka hopena o ka hoʻonāukiuki o ka waikawa i kona hoʻi hou ʻana mai ka ʻōpū),
ʻO Zollinger-Ellison syndrome - kahi neoplasm pancreatic e huna ana i nā enzyme, a me ka hoʻihoʻi ʻana i ka hana o nā waikawa,
ka hana ʻana i ka ʻōpū (gastritis), hoʻonāukiuki ʻia e nā kumu pH haʻahaʻa o ka wai momona,
kaohi ʻana o ka hoʻohuʻi ʻana i ka puna mai ka ʻōpū o ka ʻōpū o ka hanu (Mendelssohn syndrome),
nā hōʻailona o ka hōʻeha o ka wahi o ka'ōpū o ka'ōpū - kūlike, ka puʻuwai, ka belching, ʻeha.

ka hopena hoʻonāukiuki a me ka ulcerative hōʻino i nā paia o ka ʻōpū a i ʻole duodenum, me ka mea i hoʻoulu ʻia e helicobacter - kahi maʻi bacteria e hoʻonāukiuki i ka ulia.
he uliane i loko o ka ʻōpū i hoʻolele ʻia,
GERD,
ʻO ka maʻi Zollinger-Ellison.

Nā Hoʻohui

ka hoʻomaloka pilikino i ka lāʻau,
ka hana like ʻana o kekahi mau lāʻau lapaʻau i manaʻo ʻia no ka mālama ʻana i nā hua o ka maʻi, nā maʻi a me nā maʻi aʻa.
mai nā makahiki o nā keiki ma mua o 2 mau makahiki.

hypersensitivity i nā māhele o ka lāʻau lapaʻau,
ka wā gestation a me ka umauma,
keiki malalo o 12 makahiki.

Nā hopena hopena

nā pepeke
hopohopo a me ke kaumaha, nā hiamoe hiamoe,
ka hoemi ʻia ʻana o ka ʻike, auditory a me ka ʻono ʻike,
ʻeha, poʻokela,
hūnā
hoʻemi i ka hoʻoliʻiliʻi o nā puna koko āpau,
hōʻaʻe ʻia o ka ate,
ke maloʻo a me ka hoʻololi ʻana i ke ake o nā loko.
ʻehaʻeha, ʻōpū, ʻōpū,
paila, mamaila,
ʻeha i nā ʻeha a me nā ʻāpana.

nā mākau maʻi āpau
nā huakini a me ke constipation,
maloʻo ana mai ka puka waha,
jaundice
ʻeha ka ʻōpū, hakakā nui,
nāliʻi, ʻeha,
kaohi ʻana i ka hana hoʻokahe koko,
ka hoʻonui ʻana o ka umauma ma nā kāne,
ʻeha i nā ʻeha a me nā naʻau.

E hoʻokuʻu i ke ʻano a me ke kumu kūʻai

10 mau kalapona 10, 10 pcs. - 77 nā rubles.,
ʻōpiopio. 20 mg, 30 pcs. - 148 rub.,
ʻōpiopio. 40 mg, 40 pcs. - 275 rub.,
Hoʻopau i ka lyophilisate 40 mg, 1 pahu - 164 rubles.,
ʻO Omez Insta, ʻōmaʻomaʻo, 20 mg, 5 mau ʻeke - 80 rub.,
ʻO DSz Omez, nā kākā. 30 + 20 mg, 30 pcs. - 408 rub.,
ʻO nā Omez D, nā pāpū. 10 + 10 mg, 30 pcs. - 322 rub.

10 mg papa, 14 pcs. - 1079 rub.,
pakuhi. 10 mg, 7 pcs. - 986 rub.,
pakuhi. 20 mg, 14 pcs. - 2049 rub.,
pakuhi. 20 mg, 28 mau ʻopa. - 4047 rub.

Nā hōʻailona no ka hoʻohana ʻana

Hoʻohana ʻia ʻo Pariet e mālama ai:

molaki esophagitis,
ʻeha ʻōpū o ke aka,
ulia manuahi,
ʻO Zollinger-Ellison syndrome e pili ana i kahi ʻūpiki o ka islet apparatus o nā pancreas (pancreas) e hūnā ana i kahi mea hoʻoulu i ka waikila hydrochloric - gastrin,
ka maʻi palaualohi.

I ka hui pū me nā antibiotics, hoʻohana ʻo Pariet i ka eradication (antibacterial) therapy o Helicobacter Pylori. He kūpono ia i ka mea hana no ka hoʻomehana wā lōʻihi o ka gastrointestinal tract.

ʻLoe a me ke kākele

ʻArilelo ʻia ʻo Pariet no nā pākēne ma muli o ko lākou kūlana physiopathological. Eia ke ʻano a me ke ʻano i loko o nā ʻōlelo a ka mea hana hana.

Dusiaenal ulcer and gastric ulala i ka hana ikaika: 20 mg hoʻokahi manawa i ka lā, i ke kakahiaka. ʻO ka papa hana mai nā wiki 2 a i hoʻokahi mahina.
Reflux esophagitis: 20 mg hoʻokahi i kēlā me kēia lā. ʻO 1-2 mau papa ka mahina.
ʻO ka hoʻomaʻemaʻe (eradication) o H. pylori: 20 mg ʻelua i kēlā me kēia lā no ka hebedoma e hui pū me Clarithromycin a me Amoxicillin.
Me kahi ʻano maʻi o ka mumū o ka pancreas, ʻo Pariet (20 mg) i kuhikuhi i ke kakahiaka 30 mau minuke ma mua o ka ʻaina kakahiaka. ʻO ka papa papa he 4 mau pule. Hiki i ke kauka ke hoʻoponopono i ka hewa a me ke manawa.

E lawe i ka papa ʻaina piha, me ka ʻaihue ʻole, me ka nui o ka wai maʻemaʻe.

ʻO Pariet kekahi mau mea alkaline. I nā kaulike i hōʻoia ʻia, ke wikiwiki koke ʻia a hoʻomaka i ka hana i loko o ka hola, hōʻiliʻili i nā ʻoihana seletal.

Nā hopena hopena

ʻO nā hopena ʻaoʻao i ʻike ʻia i ka wā o nā haʻawina ua pōkole nō ia a ʻōlelo ʻia e:

Ma kahi o 2% o nā hanana i sporadic: rhinitis, flatulence, pharyngitis, holo aihui, nonspecific ʻeha ʻeha, flatulence, constipation a me nā insomnia. ʻOi aku ka liʻiliʻi o 1% o nā mea maʻi e hoʻopiʻi aku ai iā Pariet no ka maʻi myalgia, ka ʻeha pūwā, ka malo maloʻo, ka ʻalolilo, ka dyspepsia, irritability, etc.

Hāʻawi ʻia i ke ʻano kū like o kēia mau hōʻike, ʻike ʻia ʻaʻole i pili ka Pariet i ka kaomi. Akā, me ka hiamoe ana (hopena hopena), pono ʻoe e holo a hana a me nā hana paʻakikī.

Hoʻopili pū me nā lāʻau ʻē aʻe

ʻO ka loiloi hoʻohālikelike o ka sodium rabeprazole me Warfarin, Phenytoin, Theophylline, Diazepam ʻaʻole i hōʻike i kahi pilina koʻikoʻi klinika. ʻO ka hōʻike noi lāʻau lapaʻau e hōʻike ana i ke kūlike i ka Pariet a me ka hoʻomākaukau antacid hoʻomākaukau.

Akā pili kāna intake i ka hoʻopili ʻana o ka vitamin B12, e hoʻemi ana i kona komo. ʻO ka hui pū ʻana o ka lāʻau me Ketoconazole a i Itraconazole e alakaʻi i kahi hōʻemi o ko lākou ʻike i loko o ke koko koko, a me ka launa pū me Digoxin, ma ke ʻano, hoʻonui i kona nui i loko. ʻO ka ʻae ʻana i nā lāʻau lapaʻau me Pariet e pono nō e hana ma lalo o ka mākaʻi o ke kauka hele mai.

Hoʻomaʻamaʻa nā kauka e pili ana i nā hopena hiki ke hoʻohui i ka lāʻau lapaʻau me ka waiʻona a me ka mea inu wai i loko o ka wai, no ka mea ʻaʻole i hoʻopaʻa pono ʻia ka hoʻohālikelike ʻana me ka waiʻona o ka sodium rabeprazole.

Ka hoʻonohonoho ʻana a me ke ʻano o ka hoʻokuʻu ʻana

Kōkua ʻo Pariet e pale i nā hana o ka hoʻihoʻi o ka enzyme (proton pump) o ATPase H + / K +, e hana ana i ka hoʻoneʻe hydrochloric.

ʻO ka waiwai ikaika o Pariet ʻo ka sodium rabeprazole, kahi derivative benzimidazole i ka māhele o proton pump inhibitors. 10 a i ʻole 20 mau papa papa e loaʻa ana: mannitol, magnesium oxide, hydroxypropylcellulose, magnesium stearate, ethylcellulose, talc, titanium dioxide, hao oxide melemele, ka iron oxide ulaula a me ka carnauba wax.

Hoʻohana ʻia Pariet ma ke ʻano o nā papa i komo i loko o nā poli o 7 a 14 mau pcs.

10 mg - pōʻeleʻele, biconvex, ulana, ma kekahi ʻaoʻao ʻeleʻele e hōʻailona ana i ka "E241",
20 mg - pale melemele, biconvex, ulana, me kahi ʻulaʻula ulaula "E243".

Hoʻopili ʻia nā poli i nā pahu kāleka liʻiliʻi.

ʻŌpū a me ka lactation

ʻO ka ʻike pono e pili ana i ka maʻi ma ka palekana o ke kau ʻana i ka lāʻau i ka wā o ka gestation i nele ai. No laila, i ka wā hāpai, ua contu a Pariet.

ʻO nā hopena o ke komo ʻana o ka sodium rabeprazole i loko o ka waiū o kahi wahine hānai ʻaʻole i aʻo ʻia nā maʻi. ʻIke nā kauka hiki ʻole ke hoʻohana i ka lāʻau lapaʻau no ka umauma umauma.

Hoʻohui Kūʻai Kūʻai

Pono ke ʻano o ke kauka kauka e kūʻai i kēia lāʻau lapaʻau. I kahi helu o nā lāʻau lapaʻau, pono ia no ke kūʻai ʻana iā Parieta ma kahi waihona o 20 mg.

Omeprazole no ka pancreatitis: nā ʻōlelo pili no ka hoʻohana ʻana
Nā Papa ʻ Nlelo o ka Pancreatitis Nolpase
Pehea e lawe ai iā Nexium no ka pancreatitis?
Mexidol no ka maʻi pancreatitis

ʻO nā kauka me ka exacerbation o ka pancreatitis e hoʻolaʻa pinepine i ka wikiwiki, nā enzymes a me nā mea hōʻeha. Ua ʻōlelo mua ʻia ʻo Pariete ma hoʻokahi mahina i hala aku nei, i ka wā ua ʻeha wale ka ʻeha. ʻAʻole au i manaʻo e kōkua nui ka lāʻau lapaʻau iā lākou e wikiwiki. He hana wale nō ʻo ia - ʻo ka hoʻemi ʻana i ka huni a me ka hoʻohaʻemi ʻana i ke kaomi ma nā papa pancreatic. A me ka hoʻonui ʻana o ke kaomi ke kumu o koʻu ʻeha.

He mea paʻakikī ke hāʻawi aku i ka poʻe i kāu e ʻae ʻia. Kōkua Omeprazole i kōkua me ka kanu ʻana o ka waikawa, puʻuwai a me nā ʻeha. Akā makemake ʻo Pariet i ka wikiwiki a me ka liʻiliʻi o nā hopena ʻokoʻa, ʻoiai ke kumukūʻai kiʻekiʻe. Ua inu wau ma ka mea i kau ʻia e ke kauka no 2 mau pule i kēlā me kēia mahina. I koʻu manaʻo, e hana ʻia ke koho no ke kūpono ʻana, ʻaʻole ia he ʻemi.

Hoʻohana kēia paena i ka Akismet e hakakā ai i ka leka uila. E ʻike e pehea i ka hoʻōki ʻia o ka hōʻike ʻōlelo.

Pehea e pili ai i ka pariet?

ʻO ka hana nui ka hōʻemi i ka waikawa o ka ʻōpū, e kōkua ana i ka hoʻōla. E kōkua ka hopena analgesic e hōʻoluʻolu i kahi minuke o nā minuke.

ʻOiai ke kūpono o ka lāʻau lapaʻau, huli pinepine nā kānaka i nā ʻimi, no ka mea, ʻo ke kumukūʻai o ka lāʻau lapaʻau ma Lūkini mai 780 mau rubles.

Hoʻokuʻu i nā puka - nā papa āpau i loko o kahi pūpū. ʻOi aku ka wikiwiki o kāna hana ma mua o ka Omez.

Hāʻawi ka soaring i kahi nui mai ka puʻuwai. Pili pū ka lāʻau lapaʻau me kekahi mau lāʻau antibacterial e kuhikuhi ana i ka hoʻopau ʻana i ka maʻi i ka gastrointestinal tract. Eia kekahi, kokoke i ka nele o nā hopena o ka hopena e lilo iā ia i alakaʻi ma waena o nā lāʻau like.

Hiki ke ʻano nā ʻano hoʻohālikelike no ka hoʻohana ʻana:

ʻO ka pāpā ʻana i ka lawe ʻana i ka lāʻau lapaʻau no nā keiki ma lalo o 12 makahiki.
ʻO ka hikiʻole o Renal i ka lawe ʻana i ka lāʻau hiki ʻole ke hiki.
Lā ʻia ke koho a hoʻonui i ka dosage ʻoe iho.
ʻAʻohe hōʻoia e ke kino o kekahi mau mea o ka lāʻau.
ʻO ka ʻōpū a me ka lactation nā manawa i hiki ʻole ke lawe ʻia ʻo Pariet.

ʻAʻole ʻike ʻia ka hōʻino ʻia o ka hopena hope loa, akā ke ʻike ʻia nei nā ʻāpana o ka lāʻau lapaʻau e hiki ma ka umauma wai i ka pēpē.

Maikaʻi wale ka manaʻo o ka poʻe loea e pili ana iā Pariet, no ka mea ua hōʻike ʻia ka hiki i ka hiki ke wehe i nā ʻāpana i ke kino e hoʻolohi i ka metabolism. I kahi hihia o kahi overdose, kahi koi nui e holoi i ka ʻōpū. ʻAʻole ia he hopena ikaika, no laila ke maʻalahi ka maʻalahi e ke kino.

ʻAʻole ia o ka hopena luku i nā ʻōnaehana kino āpau. I ka wā e hoʻohana ai i nā papa, ʻaʻole pono lākou e nau ʻia. Lawe ʻia ia i ke kakahiaka ma mua o ka papaʻaina.

Ma keʻano maʻamau, ʻae ʻia ka lāʻau lapaʻau i kēlā me kēia manawa, akā i ke kakahiaka eʻoi aku ka ikaika. ʻOiai ke ʻano kūpono, he mau liʻiliʻi ia ka hopena. Inā e hoʻonui ʻoe i ka nui o nā papa i kāu iho, a laila e hoʻopau ʻia ka calcium mai ke kino, e hoʻonāukiuki i ka nui o ka loaʻa ʻana o nā iwi. No laila, pāpā pono ʻia nā lāʻau ponoʻi me kēia mea hana. ʻOi aku ka lāʻau lapaʻau ma mua o hoʻokahi loiloi maikaʻi, ʻoiai ke kumukūʻai kiʻekiʻe.

Ke hoʻohana ʻia, hiki i ka mea maʻi ke loaʻa i nā hopena ʻaoʻao.

E pili ana kēia:

nā ninia
constipation
nāwaliwali
ninini
ka malo maloʻo
ʻili kino ʻili.

ʻAʻole lawe ʻia ka Pariet me nā papa i hoʻohaʻahaʻa i ka acidity o ka ʻōpū.

ʻO ke kōkua mua no ka ʻeha o ka ʻōpū

I nā mau minuke mua o ka loaʻa ʻana o ka ʻeha ma ka ʻōpū, he mea nui ia e ʻae i kahi ʻano maikaʻi ʻole. No kēia, hoʻohana ʻia nā mea pena pena. Eia kekahi, ʻoi aku ka maikaʻi o ka hāʻawi ʻana i ka ʻai ʻana i ka meaʻai no ka manawa mua, ma mua o ka hoʻopau ʻana i kahi nui o ke inu wela a i ʻole hoʻi momona haʻahaʻa. I nā kūlana ʻē aʻe, hiki ke kōkua ʻia kekahi mau kaʻina ʻē aʻe, no ka hoʻohālike:

Me ka exacerbation o gastritis, kaukaʻi nā kauka i ke kūlana kiʻekiʻe ma ka ʻaoʻao me kou mau kuli. No ka hana nui, hiki iā ʻoe ke kau i kahi pīkī maloʻo ma kou ʻōpū a hana paha i kahi massage māmā o ka ʻōpū. I ka hihia o nā hoʻopiʻi, pono e inu i ka wai a hoʻoulu i ka luaʻi.
Me nā hōʻailona o ka makeʻana, nā arco hoʻolaʻa a me nā mea maʻi ʻē aʻe e kōkua i ka hoʻohemo ʻana i ka hōʻoluʻolu. A laila pono ʻoe e hoʻihoʻi i ka hōʻaiʻe wai i loko o ke kino me kahi inu ʻona.

ʻO ka mea e inu ai me ka ʻeha i ka ʻōpū ma ke ʻano he lapaʻau hiki ke hoʻoholo ʻia e ke kauka. ʻO ia i kuhikuhi i ka dosage a me ke ʻano o ka lawe ʻana i ka lāʻau lapaʻau. Eia naʻe, aia kekahi mau hihia i hikiʻole ke kamaʻilio me kahi loea, no laila e pono ʻoe e koho i nā lāʻau lapaʻau e pili ana i nā hōʻailona:

Me ka gastritis a he ulia paha me ka nui o ka nui o ka ʻōpū o ka ʻōpū, ka pale ʻana i ka waikawa a me ka puhi ʻana, e kōkua ana nā mea penei: Gastral, Anacid, De-nol, Flacarbin, Almagel.
Ke hōʻeha nei ka pilikia ma kaʻai pono ʻole, ka ʻai nui a me nā mea ʻē aʻe, e lawe: Gastromax, Mezim, Omeprazole, Cimetidine.
Kōkua ia i ka hoʻomaha i ka ʻōpū o ka ʻōpū: No-shpa, Besalol, Buscopan.
Mai indigestion a me ka gastritis o ka hoʻohaʻahaʻa haʻahaʻa, ua kauka nā kauka: Festal, Triferment, Panzinorm, Creon.

He aha nā kumu o ke kuhi ʻana ke ʻano, e pono ka hana e hui pū ai me ka hoʻōla kūpono. No ka manawa mua, pono ʻoe e hōʻole loa i ka meaʻai, a hala ka pilikia ʻole. Ma laila e kau ʻia ka papaʻai ma ka papa ʻaina i ʻae ʻia i ka ʻae ʻia:

Nā papa nexium 20 mg a me 40 mg

Me ka GERD me ka esophagitis, pono ʻia ʻo Nexium e 40 mg hoʻokahi manawa i ka lā no 4 mau pule. Inā, ma hope o kahi papa o ka lapaʻau, ʻaʻole i loaʻa ka hopena piha a i ʻole ka hopena o ka maʻi e hoʻomau ʻia, a laila pono ke lawe ʻia ʻo Nexium 40 mg me ka wā hoʻomaha ʻole i hoʻokahi lā i hoʻokahi mau pule he 4.

No ka mālama mālamaʻana ma hope o ka mālama ʻana o GERD me ka esosagitis erosive i mea e pale ai i ka nū hou ʻana, pono ia e lawe i Nexium 20 mg hoʻokahi lā i hoʻokahi lā no kekahi mau mahina.

Me ka GERD ʻaʻohe esophagitis, pono e lawe i ka Nexium he 20 mg hoʻokahi i ka lā no 4 wiki. Inā ma hope o ka papa o nā lāʻau, ʻaʻole i nalowale nā hōʻailona o GERD, pono ʻoe e hoʻomau i ka lawe ʻana i ka lāʻau i loko o ka hopena like no kekahi 4 mau wiki me ka hoʻolilo ʻole ʻia.

Ma hope o ka ho'ōla ʻana o GERD me ke esophagitis, hiki i ka Nexium ke "loaʻa ke koi", ʻo ia hoʻi, ke hele mai nā hōʻailona hōʻeha, pono ʻoe e inu i kahi papa papa o 20 mg e pani ai iā lākou. I ka manawa like, ʻaʻole pono ka hoʻokele hoʻomau o Nexium.

No ka mālamaʻana a me ka pale ʻana i ka hoʻihoʻi ʻana o ka ʻeha gastric a i ʻole ulia duodenal e pili ana i ka Helicobacter pylori, pono e lawe ʻia ʻo Nexium he 20 mg ʻelua mau manawa i ka lā no hoʻokahi pule. I ka mālama ʻia ʻana o ka ulupā peptic ua hoʻohana ʻia ʻo Nexium ma ke ʻano o ka hui ʻana, a i hoʻohana i ka prophylactic - i ka noho kaʻawale.

I mea e pale ai i ka hūnā i nā poʻe i loaʻa i ke koko mai kahi ulia, ʻo Nexium no ka hoʻokō ʻana i ka hoʻomoʻomaʻi ʻana i ka hoʻomehana acid-suppressing e mālama mua ʻia ma ka 40 mg hoʻokahi i ka lā no ka 2 a 3 wiki, a laila e lawe ʻia ma ke ʻano o nā papa o 40 mg hoʻokahi i ka lā no 4 wiki.

No ka ho'ōla o ka ʻeha ʻeha, hoʻonāukiuki ʻia e ka hoʻohana mau ʻana i nā lāʻau mai ka pūʻulu NSAID, pono e lawe ʻia ʻo Nexium he 20 mg a 40 mg mau lā i hoʻokahi lā no 4 a 8 mau pule. No ka pale ʻana i nā ʻeha pale a i ʻole duodenal i ka wā e lawe ai i ka NSAID, e lawe ʻia ʻo Nexium he 20 mg a 40 mg mau lā hoʻokahi i ka lā i ka wā o ka hoʻohana ʻana o nā NSAID.

No ka mālamaʻana i nā maʻi like ʻole e pili ana me ka hoʻomohala nui ʻana o ka hoʻomohala hydrochloric acid (Zollinger-Ellison syndrome, a pēlā aku), hoʻomaka ʻo Nexium e lawe i ka 40 mg ʻelua i kēlā me kēia lā.Inā ʻaʻole i alakaʻi ʻia kēia kīpē i ke kāohi ʻana o nā hōʻailona, a laila e hoʻonui ʻia i ka waiwai ma kahi o ke ʻano o ke kanaka. ʻO ka dosage kiʻekiʻe e ʻae ʻia ʻo Nexium he 120 mg ʻelua i kēlā me kēia lā.

ʻO ka hoʻohaʻahaʻa ʻana i ka hewa o Nexium i nā mea elemakule a me nā mea hoʻopilikia, ʻaʻole pono. Ma nā hōʻemi pale o ka ate, ʻo ka nui o ka lā o Nexium ka nui o kēlā me kēia lā, he 20 mg, a me ke ʻano maʻalahi a maʻalahi, e like nō ia no nā poʻe ʻē aʻe. No nā keiki ma lalo o 12 mau makahiki, ua contraindicated nā papa Nexium, a me nā ʻōpio mai nā makahiki 13 he lawe i ka lāʻau lapaʻau ma nā ʻano maʻi makua.

ʻOi aʻe ka maikaʻi: nā ʻale a me ka omez?

ʻO ka pono o Pariet ka hopena lōʻihi a me ka bioavailability kiʻekiʻe. No laila, hoʻohana ʻia ia i nā hihia koʻikoʻi e like me ka hana hou ʻana o kahi ulia ma ka ʻōpū i hana ʻia ma mua no kēia kumu. Kuhi hewa ʻole i ka hopena o ka hopena, ʻoi aku ka maikaʻi o ke komo ʻana i nā mea pili i ka lāʻau lapaʻau, ʻoiai ʻo ia ka mea e pono ai i nā mea maʻi me nā maʻi puʻuwai o ka cardiovascular, respiratory a me nā polokalamu ʻē aʻe.

Hoʻohana ʻia ka Omez no nā ʻūhā a me GERD wale nō, akā, i loko o nā kūlana haukapila maʻemaʻe: gastritis, nā hōʻailona o ka indigestion. Loaʻa maikaʻi nui o Omez ka hiki i kona koho ʻana i nā wahine hāpai a me nā keiki mai nā makahiki ʻelua (ʻo Pariet ka ʻae ʻia mai 12 wale nō, a contraindicated i ka wā hapai.

Hoʻohana wale ʻia ʻo Pariet i nā papa, a loaʻa pū kekahi i nā ʻano no ka hooponopono intravenous, nā ʻano like ʻole me ka domperidone, ka mea pono e hoʻokahuli i ka hana o ka hana o ka ʻōpala. No nā mea maʻi e paʻakikī nei i ka pau ʻana i nā papa a i ʻole nā kapa āpau, aia ka Omez Insta, kahi e hoʻomākaukau ai ka hoʻopiʻi ʻia ʻoi aku ka maikaʻi o ka ʻai ʻana.

Ua ʻoi aku ka waiwai ʻoi aku ma mua o ke ʻano o Omez, no laila ʻoi aku ka makemake, a ma nā kūlanakauhale liʻiliʻi ʻaʻole hiki ke ʻike ʻia i ke kūʻai ʻana.

ʻO Omez a i Pariet paha - ʻoi aku ka maikaʻi: ka manaʻo ʻike loea

ʻO ka poʻe loea-gastroenterologist ma nā hapa he nui Pariet, no ka mea ʻike lākou i kāna ʻoi aku ka maikaʻi a me ka hoʻomanawanui maikaʻi. Ua hoʻopaʻa ʻia kēia ma nā haʻawina loea. ʻO ka hapa nui o nā loiloi lapaʻau e hōʻike ana i ka palekana o Parieta i ka poʻeʻelemakule, e koi mau nei e lawe i nā nui o nā lāʻau lapaʻau. ʻO Omez, i hāʻawi ʻia i kona pili ʻana i nā lāʻau lapaʻau, ʻaʻole kūpono i kēia hihia.

ʻO ka pilikia wale nō i ka manawa ʻo Pariet kona kumukūʻai nui: ʻaʻole hiki i nā mea āpau ke kūʻai. No laila ua hāʻawi ʻia i nā hihia koʻikoʻi hou aku. A no ka mālama ʻana i ka gastritis maʻamau, ʻo GERD me ka pau ʻole a me nā kumu prophylactic i kuhikuhi ʻia me Omez.

Hoʻopau (pellets a gruble no ka hoʻonā) Nexium - nā ʻōlelo aʻoaʻo no ka hoʻohana

Hoʻohana nā pale a i nā grulle no ka hoʻomākaukau ʻana i kahi hoʻopiʻi waha. No ka hoʻomākaukau ʻana i ka pīhoihoi, pono e hoʻokaʻawale ʻia nā ʻike o hoʻokahi ʻeke Nexium i 15 ml o ka wai wai, hui maikaʻi a kali i 30 mau kekona a neʻe ʻia kahi hoʻopiʻi homogeneous. Inā pono ʻoe e lawe hou aku ma mua o hoʻokahi sachet o ka lāʻau lapaʻau, a laila e helu pono ka nui o ka wai ma ke kumu o ka 15 ml no 1 mau pā. ʻO ia hoʻi, e hoʻoheheʻe i ʻelua mau pulu o nā manu (pellets) Nexium ka pono i 30 ml o ka wai, etc. E ʻohi koke kolohe ke hoʻopau ʻia no ka lōʻihi o ka hapalua hola. Ma hope o ka inu ʻana i ka pāpā, hoʻohui i kekahi 15 ml wai i ka aniani hoʻokahi, e hoʻomoʻi i ka huahana i ke koena a inu hou i ka hopena hopena. No ka wikiwiki o ka hoʻomākaukau ʻana o ka hoʻonā Nexium, ʻaʻole pono e wāwahi ʻia nā ʻāina a maʻa paha.

Hoʻoholo ʻia ka wā maʻi a me ka lōʻihi o ka mālama ʻana e ka makahiki o ke kanaka a me ke ʻano o ka maʻi.

No nā keiki i hala 1 a 11 mau makahiki me ke kino o ke kino ʻoi aku ma mua o 10 kg, pono e hāʻawi ʻia nā pelika Nexium wale nō no ka mālama ʻana o GERD. ʻO ka Therapy o GERD me ka esophagitis i loko o nā keiki me ka paona o ke kino he 10 - 20 kg e lawe ʻia ana me Nexium 10 mg (1 sachet) 1 ka manawa i ka lā no 8 mau pule. Inā ʻoi aku ka nui o ke kaumaha o ke keiki ma mua o 20 kg, a laila no ka mālama ʻana o GERD me ka esophagitis, hiki iā ia ke lawe i ka Nexium 20 mg (2 mau pēpē) hoʻokahi i ka lā hoʻokahi no nā hebedoma. No ka mālamaʻana iā GERD me ka esophagitis, pono nā keiki e lawe iā Nexium 10 mg (1 sachet) 1 manawa i ka lā no 8 mau pule.

ʻO nā ʻōpio a me nā keiki ma mua o 12 mau makahiki ke lawe lākou i nā pellets Nexium (mau granule) i nā papa like a me nā ʻano like me nā papa like a me nā kānāwai like ʻole (e ʻike i ka pauku "Nexium 20 mg a me nā papa 40 mg - nā ʻōlelo aʻoaʻo no ka hoʻohana").

ʻAʻole pono ka hōʻemi ʻia o ka hoʻoneʻe ʻana i nā ʻelemakule, i loko o ka poʻe e hōʻeha nei i ka hiki ʻole o ke kua a me ke ʻano maʻalahi a i ʻole ke ʻano o ka hōʻeha ʻana o ka ate. Ma ka hōʻoki hewa o ka ate, ua palena ʻia ka nui o ka make ʻana o Nexium ma 20 mg (2 mau pēpē) i kēlā me kēia lā.

Lyophilisate Nexium - nā ʻōlelo hoʻohana no ka hoʻohana ʻana

Hoʻohana ʻia ka ʻokiʻoki ʻana o ka lāʻau lapaʻau ke hana ma ke ʻano he papa hana a me nā pellets inā ʻaʻole hiki i kekahi kanaka ke hoʻolele i ka lāʻau lapaʻau no kekahi kumu. Ma ke ʻano o ka hiki ke kō i ka lāʻau lapaʻau ke hoʻihoʻi ʻia, ua lawe ʻia ke kanaka i ka hoʻokipa ʻana iā Nexium ma ke ʻano o nā papa a i ʻole nā pellets. Hoʻoholo ʻia ka nui o ka hoʻokele ʻana o Nexium e ke ʻano o nā maʻi.

No ka hoʻolālāʻana o GERD me ka esophagitis, mālama ʻia ʻo Nexium ma ke 40 mg (1 pahu) hoʻokahi i ka lā. No ka hoʻopau ʻana i nā hōʻailona o GERD, e hoʻomau nei me ka esophagitis, 20 mg (hapa hapalua bole) o ka lyophilisate ka lawelawe.

No ka ho'ōla a me ka pale ʻana o nā hewa ulcerative i hoʻopili ʻia me ka hoʻohana ʻana o nā NSAID, e mālama pū ʻia ka Nexium me 20 mg (hapalua ka hue) i hoʻokahi lā.

I mea e pale ai i ke kahe mai ka maʻi ulia maʻi ma hope o ka endoscopy, pono e lawelawe ʻia ʻo 80 mg (2 mau bole) o Nexium me kahi infusion mau i ka hapalua hola. A laila, ua lawelawe ʻia ʻo Nexium ma ke ʻano o kahi dropper (infusion) ma ka nui o 8 mg mau hola no 3 lā. Ma hope o ka pau ʻana o ka hoʻokele intravenous o Nexium, pono ʻoe e hoʻololi e lawe i ka lāʻau lapaʻau ma ke ʻano o nā papa a i nā pellets o 40 mg hoʻokahi i ka lā no nā hebedoma 4.

Na rula no ka hoʻomākaukau ʻana i nā hopena no ka maʻi intravenous injection a me infusion (droppers):

Pono e hoʻopau ʻia ʻo ka Lyophilisate me ka paʻakai momona,
ʻAʻole hiki ke hui pū ʻia ka hopena nexium mākaukau i hoʻomākaukau ʻia me nā lāʻau ʻē aʻe,
Pono e kūleʻa ʻia ka hopena me ka ʻole o nā mea maʻemaʻe a me nā flakes.
Pono e mālama ʻia ka mea hoʻonāi ma hope o ka hoʻomākaukau ʻana a i ʻole lōʻihi o 12 mau hola.
Hiki iā ʻoe ke mālama i ka hoʻonā i kahi mahana ʻaʻole iʻoi aku ma mua o 30 o C,
No ka hōʻemi ʻana, pono e hoʻopau ʻia ka lyophilisate mai hoʻokahi pahu me ka hoʻohui ʻana i ka 5 ml o ka paʻakai physiological,
No kahi dropper (infusion), pono ia i ka lyophilisate mai hoʻokahi pahu wai i 100 paʻakai.

Nā rula no ka hoʻokō intravenous i kahi hopena lyophilisate:

ʻO 40 mg a 20 mg paha o Nexium (1 a i ʻole ka ipu he 0.5 līlī ʻia o ka lyophilisate i hoʻopau ʻia) e lawelawe ʻia no ka liʻiliʻi he 3 mau minuke,
ʻO 40 mg a 20 mg o Nexium (1 a 0.5 paha vial o ka lyophilisate i hoʻopau ʻia) e lawelawe ʻia ana he infusion ma luna o kahi manawa o 10 a 30 mau minuke,
80 mg o Nexium (2 mau hāmeʻa) i lawelawe ʻia e like me ka infusion no ka liʻiliʻi 30 mau minuke,
Pono e hoʻokaʻawale ʻia nā koena āpau o ka lyophilisate, ʻaʻole mālama.

Inā ʻike ʻoe i ka luaʻi, paʻakikī paʻakikī, a i ʻole ke lilo ʻana o ke kino luhi i ke lawe ʻana iā Nexium, pono ʻoe e ʻimi i ke kauka a e nānā ʻia no nā ala ʻē aʻe. Ke lawe nei ʻo Nexium ma mua o hoʻokahi makahiki, pono ke nānā ʻia e ke kauka. Inā i ka wā o ka hoʻohana ʻana o Nexium "ma ke noi" ua loaʻa he loli ma nā hōʻailona, a laila pono e kiʻi aku i ke kauka i ka hiki.

Hoʻopili pū me nā lāʻau ʻē aʻe

Hoʻopili ʻo Nexium me nā maʻi maʻi HIV / AIDS (atazanavir, ritonavir, nelfinavir, saquinavir), e hana ana i nā loli i ko lākou komo ʻana a me ke kūpaʻa o ke koko. Eia kekahi, ʻo ka piʻi ʻana o ka loaʻa ʻana o nā lāʻau antiviral ʻaʻole pale i ka hopena o Nexium, no laila, ʻaʻole hiki ke hoʻohana pū ʻia kēia mau lāʻau.

Ke alakaʻi nei ʻo Nexium i ka hoʻonui ʻia ʻana o ka neʻe o ke koko o nā lāʻau lapaʻau e hiki mai ana:

Diazepam
Makahiki,
Imipramine
Clomipramine,
Phenytoin
Cilostazol

Me ka hoʻohana pū ʻana o Nexium me nā lāʻau lapaʻi aʻe i luna, e hoʻemi ʻia ka nui o ka hopena o ka hopena ma o 30 - 40%.

ʻO Rifampicin a me nā mākaukau e pili ana i nā māhele wort o St. John e alakaʻi i kahi emi ʻana o ka neʻe ʻana o ka nexium ma ka hui koko.

Nexium no nā keiki - pehea e lawe ai

ʻO nā keiki me ke kaumaha o ke kino e emi iho ma lalo o 10 kg a emi mai ka 1 makahiki, ʻaʻole pono lākou e lawe iā Nexium. ʻO nā keiki i hala 1 a 11 mau makahiki me ke kaumaha o ke kino he 10 a 20 kg hiki ke lawe wale i ka 10 mg (1 sachet) o Nexium i hoʻokahi lā. Ke kaupaona nei nā keiki ma mua o 20 kg hiki iā 20 mg (2 mau pēpē) o Nexium i kēlā me kēia lā.

Hoʻohana wale ʻia ka Nexium i nā keiki no ka mālama ʻana iā GERD, ka mea e loaʻa ana i loko o ka lā o ka lā he 10 mg a 20 mg o nā pellets no 8 mau pule.

Nexium - nā kikowaena

Nā ʻonymslelo like o Nexium i nā ʻōlelo penei:

Neo-Sext
Nā papa papa ʻomoma Esomeprazole
Eʻula pū me Emanera.

Nā ʻōlelo ʻ oflelo o Nexium:
1. ʻO nā ʻāpana lau,
2. ʻO nā kālena Gastrozole,
3. Helikon capsules,
4. Dexylant kapiale,
5. Zhelkizol lyophilisate,
6. Nā ʻōkuhi Zerocide,
7. ʻO nā papa Zipantola
8. Nā papa lāʻau Zolispan
9. ʻO nā papa ʻula Zulbeks
10. ʻO nā papa pākuʻi a me ka ʻōpala no ka hoʻomākaukau ʻana o ka hopena no ka hoʻokō intravenous,
11. Nā papa krosacid
12. Kapai Lanzabel,
13. Kapai Lanzap,
14. Kapakai Lansoptol,
15. Lansoprazole Stada Capsules,
16. Nā lole lansofed,
17. Nā pale lantsid,
18. ʻO nā papa pihi a me nā lyophilisate,
19. ʻO Kamikole ʻO Lozenzar-Sanovel,
20. Nolpase papa,
21. Nā papa Noflux
22. ʻO nā kāpena Omez a me ka lyophilisate,
23. ʻO ka pauku Omez Insta no ka hoʻokuʻuʻana i ka waha,
24. ʻO nā ʻōkuhi Omecaps,
25. Omeprazole kapoti,
26. ʻO nā ʻōpiapipi Omeprus,
27. ʻO nā kāpena Omefes,
28. ʻO nā ʻōkuhi Omizak,
29. Omipix kapsul,
30. Omitox kapsul,
31. Nā papa āpau
32. ʻO nā kapiki Orthanol,
33. Kapoma Ocid,
34. Nā papa Pantaz
35. Panum Pills,
36. ʻO nā lālī waiwai
37. Kapeke a Parkour,
38. ʻO nā papa papa Peptazole
39. Nā Pizhenum - Nā ʻonopoli Sanovel,
40. ʻO nā ʻōleʻa Pleoma-20,
41. Hoʻopiʻi nā kōpona
42. Nā papa piloref,
43. Nā Kiʻi-Rabeprazole-OBL
44. Rabelok lyophilisate,
45. ʻO nā kapuwai Romesek,
46. Nā papa Sanpraz a me nā lyophilisate,
47. Nā kākoi Sopral
48. ʻO nā kapcosa Ulcosol a me nā lyophilisate,
49. Pālua loa,
50. Nā kime ulula a me nā lyophilisate,
51. ʻO nā papa ʻo Hayrabesol,
52. Nā pāpale pepehi pepehi a me ka lyophilisate,
53. Nā kapuwai o Cisagast,
54. Nā kākō Epicurus.

Nā Hōʻike Manaʻo Nexium

ʻO kahi helu liʻiliʻi o nā loiloi maikaʻi e pili ana i ka lāʻau Nexium ka mea maʻamau ma muli o kona hiki ʻole ʻana. ʻO ka manawa pinepine loa, ʻo ke kumu o nā loiloi maikaʻi ʻole ke manaʻolana nui e pili ana i ka lāʻau, ke noʻonoʻo nei ka poʻe i ka "magic pill" ʻaʻole e hoʻopau wale i nā hōʻailona aiʻole e hoʻōla i ka maʻi, akā e hoʻōla lākou.

ʻO Omez a i ʻole Nexium?

ʻO ke kumu o ka hana kiʻekiʻe o Nexium ʻo ia kona bioavailability kiʻekiʻe, ʻoi aku ka maikaʻi o nā mea āpau o nā lāʻau āpau mai ka pūʻulu o nā proton pump inhibitors o ka hanauna mua, aia kahi o Omez. E hōʻoiaʻiʻo ʻia ana ka bioavailability o Nexium e kona ʻano kemika kūikawā, ma muli o kona hiki ʻana i nā ʻōpū o ka ʻōpū ma kahi nui he nui loa i hoʻohālikelike ʻia me Omez. Eia kekahi, hiki i ka Nexium ke mālama i ka paʻa mau a paʻa mau i loko o ke koko ma hope o ka ingestion, ʻoiai ʻaʻole naʻe ʻo ka Omez. Ke lawe nei i ka Omez, ʻano nui ka ʻike o ka mea hana i loko o ke koko, kahi e hoʻoiho ai i ka hopena heterogeneous therapeutic ma mua o ka manawa.

I ka hopena o nā hopena therapeutic, ʻo nā pōmaikaʻi o Nexium ma luna o ka Omez penei:
1. ʻOi aku ka maikaʻi a wānana pololei i ka hoʻololi ʻana i ka paʻakai gastric.
2. ʻO kahi pālahalaha kiʻekiʻe o nā hoʻōla i ka wā o nā papa pōkole o ka maʻi.
3. ʻO ka hoʻopauʻana i nā hōʻailona hōʻeha a me ka hoʻōla ʻana o nā meaʻino i nā membous mucous o ka ʻōpū, duodenum a me esophagus.
4. Hoʻonui i ka heartburn a me nā hōʻailona ʻē aʻe o GERD i ka nui o nā mea maʻi.

Ma kāna hana pilikino, ʻoi aku ka maikaʻi o Nexium ma mua o nā lāʻau āpau o ka pūʻulu hoʻomehana proton. No laila, i ka wā o nā hoʻokolohua lapaʻau i ʻike ʻia e hoʻōla maoli ʻo Nexium i ka GERD i loko o hoʻokahi mahina, a pono e koi ʻo Omezu i ʻelua mahina e hoʻokō ai i nā hopena like.

Ke mālama nei i ka ʻōpū a i ʻole ulī duodenal e pili ana me ka Helicobacter pylori, ka hoʻohana ʻana o Nexium i ka hui pū me nā antibiotics e kinai ai i ka hopena o ka microbe i ka hōʻeha a me ka ʻeha ʻo ka ʻōpala i nā lā ʻehiku lā. No ka hoʻohālikelike, pono ʻoe e ʻike i ka maʻamau maʻamau me ka omez a i ʻole kekahi proton pump protector e hana ʻia i loko o nā hebedoma ʻekolu. ʻO ia ka mea e hoʻohana ai iā Nexium i loko o ka hui hoʻohui ʻana o ka uluna peptic e hōʻemi ana i ka lōʻihi o ka lapaʻau i nā manawa ʻekolu.

No laila, hiki iā ia ke hoʻohālike i ka ʻōlelo ʻo Nexium ka maikaʻi aku a me ka ʻoi aku o ka haukapila kiʻekiʻe e hoʻohālikelike ʻia me Omez.

Nexium a i ʻole Emanera?

Ma ka hana ʻana o ka hana kanu mua, ua hana ʻia ke kāpili a ka haʻalele ʻana i ka mea ikaika, ka hoʻomaʻemaʻe ʻana a me ka hoʻomaʻamaʻa ʻana pono o nā waiwai. Ma hope wale nō o ka hoʻomohala ʻana i kahi ʻenehana no ka hoʻomākaukau a hoʻomaʻemaʻe ʻana i kahi waiwai mai nā haumia i hoʻokomo ʻia i loko o ka mana o ka lāʻau a mālama ʻia e ka make. ʻAno kūlohelohe, nā ʻuhane a pau o ka ʻenehana no ka hana ʻana i ke ʻano ikaika i nā mea huna a me ka ʻenehana. Akā hiki i nā hui ʻē aʻe ke hoʻokaʻawale i kēia mea a hoʻokuʻu i ka lāʻau lapaʻau ma lalo o kahi inoa ʻē aʻe, e manaʻo ʻia he mau mea maʻamau, no ka mea, ʻo ka mea nui i ka loaʻa ʻana o kahi pūlea kemika a mea e hopohopo hou.

ʻAʻole hoʻomaʻemaʻe maikaʻi nā ʻoihana ʻōnaehana i ka mea ikaika e hoʻohana pono ai, hoʻohana i nā mea kōkua kōkua, e like me ka hopena i hiki ke loaʻa i ka lāʻau lapaʻau ka nui kiʻekiʻe a me ka hōʻeha o nā hopena ʻokoʻa, a ʻoi aku ka haʻahaʻa o ka maʻi ma mua o ka mea maoli. No laila, ua ʻike maopopo ka ʻokoʻa ma waena o ka mea mua a me ka mea maʻamau.

Eia nō naʻe, ʻaʻole ʻo Emanera kahi maʻamau maʻamau i hana ʻia e nā limahana lāʻau lapaʻau e nui o India. ʻO ka mea ʻoʻo ia ʻo Emanera i hana ʻia e ka punahele lapaʻau maikaʻi ʻo Krka, ʻo ka mea i hāʻawi ʻia i ka palapala e pono ai e hoʻomohala i ka lāʻau lapaʻau kūikawā e loaʻa ai ka lāʻau lapaʻau kūpono. No laila, heʻokoʻa ʻole ka ʻokoʻa ma waena o Emanera a me Nexium, a hiki iā ʻoe ke koho i kekahi lāʻau lapaʻau. Inā pono e hoʻemi i ka uku o ka mālamaʻana, no laila pono ke koho pono ʻia ʻo Emanera. A i ka nele o kekahi o nā kaupalena, hiki iā ʻoe ke koho iā Nexium. Inā ʻaʻohe mea hoʻonaʻauao kikoʻī e koi ai iā mākou e koho iā Nexium a i ʻole Emanera, a laila hiki iā ʻoe ke kūʻai i kekahi lāʻau lapa āu e makemake ai i kekahi mau kumu pili kumuhana, no ka hoʻohālike, ʻoi aku ka maikaʻi o ka pale, etc.

Nexium - pehea e kūʻai ai?

Loaʻa ka ʻike inaccurate i kekahi manawa ma ka Pūnaewele ma kēia pilikia, no laila e hoʻomaopopo mākou i nā kikoʻī.

Omeprazole a rabeprazole pili aku nā pale pale proton (IPP). ʻOnone - proton pump blockers . ^ E Ha yM. ʻO kēia mau lāʻau i keakea i ka mea huna o ka waikila hydrochloric (HCl) i loko o ka ʻōpū, no laila e pili ana lākou nā lāʻau antisecretory a hoʻohana e mālama i ka nui o ka momona o ka ʻōpū. Ka pale aku o ka palaka pale (proton pump blockers) hoʻemi ʻia ka mea huna nā ʻona hydrogen (H +, i ʻole proton) lining (parietal) mau loko o ka ʻōpū o ka ʻōpū. Hoʻokomo ʻia ka hana huna i ka pahuhio pākuʻi extracellular (K +) i ke komo ʻana i loko o ke kulana e hoʻololi ai no ka hoʻopau ʻana o ka ion hydrogen (H +).

Palani a me keʻano

Ke noi nei i kēia manawa 3 mau pūʻulu nā lāʻau e hōʻemi ana i ka acidity i loko o ka'ōpū:

nā pale pale proton - nā palekana antisecretory ikaika loa e pale i ka hoʻokumu ʻana o ka waikila hydrochloric ma loko o ka ʻōpū. Hana ʻia 1-2 mau lā i ka lā,
H 2 mau mea hoʻohana (heluhelu al-ʻelua) - he mau haʻahaʻa ko lākou antisecretory haʻahaʻa a no laila hiki ke kuhikuhi ʻia i nā hihia haʻahaʻa wale nō. Lawe ʻia lākou i 2 mau manawa i kahi lā. Hoʻokaʻa ʻia ka ʻenekini histamine (H 2 -) i nā sela parietal o ka mucosa gastric i kālai ʻia. H 2 blockers e komo raniani a famotidine .

No ka ʻōlelo: H 1 -llockers hana i nā kūlohelohe (loratadine, diphenhydramine, cetirizine a me kekahi).

antacids (ma ka unuhi ʻana "e kū'ē i ka waikawa ") - ke kumu e pili ana i nā hoʻohui pūnaehana o ka magnesium a i ʻole alumini, e hoʻohemo koke i ka hoʻopili (hoʻopaʻa ʻia) waikela hydrochloric i loko o ka ʻōpū. Pākuʻi kēia almagel, phosphalugel, maalox a me kekahi poʻe ʻē aʻe, hana wikiwiki lākou, akā no ka manawa pōkole (i loko o hoʻokahi hola), no laila e lawe pinepine ʻia lākou - 1.5-2 mau hola ma hope o ka ʻai ʻana a ma mua o ka hiamoe. ʻOiai ʻo nā antacids e hōʻemi i ka acidity i loko o ka'ōpū, hoʻonui lākou i ka hoʻopili kino ʻana i ka waikena hydrochloric e ka mīkini manaʻo maikaʻi ʻole no ka mea hoʻāʻo ke kino e hoʻihoʻi i ka pH (acidity, na ia mai ka 0 a ka 14, ma lalo o 7 - kahi kūmole acid, ma luna o 7 - alkaline, pololei ʻo 7 - neʻe iki) i nā waiwai o mua (maʻamau pH i loko o ka'ōpū o 1.5-2).

I nā pale pale proton komo:

(nā inoa kālepa omez, moose, ultop ),
(nā inoa kālepa Nexium, Emanera ),
lansoprazole (nā inoa kālepa ʻōwili, lansoptol ),
pantoprazole (nā inoa kālepa nolpaza, kāohi, pale ʻana i ka maʻemaʻe ),
rabeprazole (nā inoa kālepa ʻeha, noflux, ontay, zulbeks, hairabesol ).

Kūleʻa kumukūʻai

Omeprazole kumukūʻai mau manawa ʻoi aku ka liʻiliʻi ma mua rabeprazole .

ʻO ke kumu kūʻai o nā generics (analogues) no 20 mg o nā 30 mau papa ma Moscow ma ka lā 14 Pepeluali, 2015 mai 30 a 200 mau rubles. No ka mahina o ka mālama ʻana, pono ʻia nā 2 pā.

ʻO ke kumukūʻai o ka lāʻau kanu kumu Nā Waʻo (rabeprazole ) 20 mg 28 mau papa. - 3600 ʻōpala. No ka mahina o ka mālama ʻana, pono ʻia ka pākeke 1.
(nā analogues) ʻo rabeprazole ka mea maʻalahi:

Halawa 20 mg 20 pākaukau. - 1100 ʻōpala.
Zulbeks 20 mg 28 mau papa. - 1200 ʻōpala.
Kui kaoli 20 mg 15 mau papa. - 550 rub.

I keia ala kumukūʻai mālamakēlā me kēia mahina mea ma kahi o 200 rubles (40 mg / lā), rabeprazole i ka wa e hoʻohana ai huluhulu - e pili ana i 1150 mau rubles. (20 mg / lā).

ʻO nā ʻokoʻa ma waena o ka omeprazole a me esomeprazole

He S-stereoisomer (waiho lima optic isomer), ka ʻokoʻa me ka isomer lima hema ma ke ʻano like me ka hema a ma ka hema a i ka hema a me ka pae pae hema. Ua hoʻohuli ʻia ka ikaika o ka R-form (ʻoi aku ma mua o ke ʻano S-puka) i ka wā e kahe ana i ka ate a no laila ʻaʻole i hōʻea i nā lula o ka ʻōpū. Omeprazole he lwihua o kēia mau mea hoʻokele ʻelua.

Wahi a nā puke moʻolelo, he pono maikaʻi kāna i hoʻohālikelike ʻia, akā e ʻoi aku ke kumukūʻai ʻoi aku. lawe ia ma ka inea like me.

Uila nā inoa kālepa:

Nexium 40 mg 28 pā. - 3000 rub.
Emanera 20 mg 28 mau papa. - 500 rub. (2 mau pālule i hoʻokahi mahina).

Loaʻa i nā pono o rabeprazole ma luna o nā PPI'ē aʻe

Hoʻohuirabeprazole hoʻomaka i loko o 1 mau hola ma hope o ka hoʻokele ʻana a noho ʻo 24 mau hola. Ke hana nei ka lāʻau lapaʻau i kahi ākea pH nui (0.8-4.9).
ʻĀnō ʻO rabeprazole ka 2 mau manawa haʻahaʻa i hoʻohālikelike ʻia me omeprazole, kahi e hāʻawi ai i ke ahonui i ka lāʻau a ʻoi aku nā hopena liʻiliʻi. No ka laʻana, i ka noiʻi hoʻokahi, nā hopena ʻao (hōʻeha, hōʻeha, ka ʻeha, ka ʻōpū, ka rashes ʻili ) ua kālai ʻia 2% i ka malama ana rabeprazole a me ka 15% i ka wā mālama.
Kono rabeprazole i loko o ke koko mai nā ʻunina (bioavailability) ʻaʻole i hilinaʻi i ka manawa o kahi pāʻina.
Rabeprazole ʻoi aku ka hilinaʻi hoʻokaʻawale i ka mea huna o ka waikole hydrochloric, no ka mea, ʻaʻole i hilinaʻi ʻia ka luku ʻana i ka ate ma ka ʻano like o ka ʻano o ka nui o ka cytochrome P450. No laila, hiki ke hoʻoholo pono i ka hopena o ka lāʻau i nā mea maʻi. ʻO Rabeprazole ka liʻiliʻi ma mua o nā lāʻau lapaʻau e pili ana i ka metabolism (luku ʻia) i nā lāʻau ʻē aʻe.
Ma hope o ka haʻalele rabeprazoleʻaʻohe "ʻokoʻa hōʻano hou" (hiki'ōloli), i.e. ʻaʻohe kūpono o ka uku koi i ka kiʻekiʻe o ka acidity i loko o ka ʻōpū. Hoihoi hou ʻia ka hoʻokahe ʻana o ka wai hydrocloric (i loko o 5-7 mau lā).

Nā hōʻailona no ka lawe ʻana i nā mea pale o nā proton pump

maʻi maʻi reflux gastroesophageal (Reflux o ka waikona i loko o ka ʻōpū o ka ʻōpū i loko o ka esophagus),
pathers hypersecretion o ka waikila hydrochloric (komo me Zollinger-Ellison syndrome),
ma ka hoʻomaʻamaʻa paʻakikī ʻana e hoʻohana ʻia e hoʻopau (hoʻopau i ke ʻano) Helicobacter pylori maʻi (Helicobacter pylori), ka mea e hōʻeha ai i nā maʻi ʻeha a me nā maʻi gastritis.

Hoʻomaopopo All pale proton pump inhibitors luku ʻia i loko o kahi pānaehana , no laila, aia i loko o ke ʻano o nā capsules a i ʻole nā papa i komo, ka mea Pau loa (ʻaʻole hiki iā ʻoe ke chew).

Hoʻolaha: rabeprazole ≅ esomeprazole> omeprazole, lansoprazole, pantoprazole .

Ma ka kikoʻī: rabeprazole ua mau mau pono ma mua o nā pale pale proton hou aʻe a ma nā ʻōlelo e hoʻohālikelike ʻia me, akā naʻe, ka mālama ʻana rabeprazole kumukūʻai 5 manawa ʻoi aku ke kumukūʻai a hoʻohālikelike ʻia.

Wahi a ka palapala, ʻo ka hopena o ka make ʻana o ka Helicobacter pylori, ʻaʻole ia e hilinaʻi i ke koho ʻana o kahi pale proton pump (ʻoi aku paha kekahi), ʻoiai i ka mālama ʻia maʻi maʻi gastroesophageal ua hōʻike aku ka hapa nui o nā mea kākau rabeprazole .

Ka hoʻohālikelike o ka lāʻau antihypertensive

I waena o nā pale pale proton 3 mau huahana i kuhi ʻia:

(lauka lāʻau me nā hopena ʻaoʻao)
(kahi mākaukau hoʻomaikaʻi ʻia e pili ana i ka S-stereoisomer o omeprazole),
rabeprazole (palekana loa).

Loaʻa nā kaulike like i waena o nā mea i hoʻohana e mālama i ka maʻi hypertension:

amlodipine (me nā hopena ʻaoʻao)
levamlodipine (kahi mākaukau hoʻomaikaʻi ʻia e pili ana i ka S-stereoisomer me nā hopena ʻokoʻa liʻiliʻi),
lercanidipine (palekana paʻa).

Nānā 7 i ka leka "Ma hea ka maikaʻi - omeprazole a i ʻole rabeprazole? ʻO ka pono o rabeprazole "

Loaʻa nā pōmaikaʻi o Hyrabesol:
Noi ʻia aku ʻo Hyrabezol no kāna mau keiki ma mua o 12 mau makahiki.
ʻO 3 mau makahiki ʻo ka pale o Hyrabesol.
Hoʻomili kūleʻa braille.
Kūʻokoʻa kū ʻole ʻo Hyrabezol i ka kōʻai ʻana o ka meaʻai

ʻO kaʻu moʻolelo kēia: ke kauka nei ke kauka iā Ultop noʻu. Ma hope o ke hoʻohana ʻana i hoʻokahi ʻaoʻao, loaʻa nā hopena maikaʻi loa: kahi hōʻeha ʻeha, ua ʻulaʻaka a hoʻomaka ke ʻike maikaʻi ʻole i ka maka, nā palpitations a me ke ʻala. Ua haʻi ʻo Dokhtura e pili ana i kēia, akā ʻaʻole ʻo ia i manaʻo mai iaʻu - ʻōlelo ʻo ia ʻaʻole hiki ke loaʻa nā hopena mai ka hopeop a i hoʻopaʻa ʻia ʻo Omez-insta. Hele wau i ka home, ua hoʻoholo wau e heluhelu, akā huli ʻia ka papa i like pū ka mea like ʻole, ma lalo o kahi inoa ʻē aʻe!

Ma keʻano holoʻokoʻa, mahalo iā ʻoe, ua hoʻomālamalama wau a e ʻimi au noʻu iho kahi mea pono hou me ka ʻole o ka hopena weliweli. Manaʻo wau e hiki iaʻu ke loaʻa kahi gastroenterologist maikaʻi i kēia manawa (((((

4 mau makahiki i hala aku nei, ua mālama ʻo ia i ka gastritis me kahi ultrasound, ʻoiai, ʻaʻole i kōkua, no ka mea ua ʻike ʻia ka hiolo ʻana o ka ʻōpū i kēia makahiki. zulbeks i ʻōlelo ʻia. ʻAʻole wau i hele i ka honua aʻe me 2 papa: i hoʻokahi hola ma hope o ka lawe ʻana i ka lāʻau lapaʻau, maʻi koʻu ʻūhā i ka lā mua a hoʻomaka ka huhū ʻana, ua nalowale koʻu make ʻana, a i ka kakahiaka ma ka lā lua aia kekahi ʻeha ma ka ʻōpū ma lalo o nā ʻōpū me ka cystitis. eia nō naʻe, ua hoʻoholo e inu i kekahi ʻāpana. hou, hoʻokahi hola ma hope o ke kau ʻana, ua ala ke mahana 38,5, ua maʻi ka hope o ke kua, ʻaʻole pono ke poʻo i ka ʻoli, nui ka ʻeha i loko o ke kino holoʻokoʻa, ua ʻā nā mea āpau i loko. Heluhelu wau i nā hopena ʻaoʻao wale nō ma hope o ka zulbeks i hoʻomau pinepine i nā maʻi like me ka maʻi a me nā maʻi o ka ʻōnaehana genitourinary. a ʻo ka mea maikaʻi loa kēia e makemake ai e ʻōlelo. me ka ultrasope ʻaʻole kēia, ka waha nui loa a me ka nalowale o ka makemake. ma ke ala, paha paha kahi dosis o 20 mg nui loa iaʻu, no ka mea koʻu paona he 39 kg

ʻO ka mea pōʻino, ʻo Zulbeks (rabeprazole), ʻoiai ʻo kona mau pōmaikaʻi, ʻaʻole ia e like me ka mea e like me ka mea ma mua. Ma ka ʻaoʻao ʻē aʻe, hiki iā Ultop (omeprazole) ke hana i kahi momona maʻamau, nāwaliwali ākea, ka loaʻa ʻana o ka paona, a me ka maʻi hoʻi. Ua wehewehe ʻia kēia mau hopena i nā kauoha i ka lāʻau. ʻOiai ʻo ka dosage, ʻo 10 a 20 paha o ka rabeprazole i kēlā me kēia lā (ʻaʻoleʻoi aʻe ma mua o 20 mg) e hoʻohana pinepine. No laila, ʻaʻole pono ʻo rabeprazole iā ʻoe, pono ʻoe e hoʻi i omeprazole a e hoʻāʻo paha i ka esomeprazole.

Mahalo i ka ʻōlelo. Heluhelu wau, akā he kauka i kuhikuhi iā lākou iaʻu, a ʻōlelo mai ʻo ia i hōʻemi ʻia ka lāʻau lapaʻau a kōkua maikaʻi loa ia. Akā, mai haʻi iaʻu pehea ka lōʻihi o ka hoʻopā piha ʻana i ke kino? I kēia lā ʻaʻole wau i lawe i kahi mau pōpoki, akā e pili ana i koʻu wahi wela ma ka 37.3, ua hoʻi koʻu ʻeha, ua emi koʻu ʻeha, ua maʻule koʻu ʻupena, ua hoʻi mai koʻu makemake. ʻo ka manawa hope loa au i lawe ai i ka lāʻau i ka lā i hala. e pili ana i ka hopeop i hoʻomanaʻo wau mai ia ia mai ka hū o koʻu lauoho a me ka ikaika loa (ua haʻi ʻia kēia ma nā ʻōlelo).

Hoʻomaka wale ʻia aku ʻo Rabeprazole o ke kino mai ke kino wale nō, ke noho nei wale nō ma hope o ke ao, akā naʻe, e mau ana ka hopena o ka lāʻau i ka lā. Loaʻa paha, i 4-5 mau lā, e pau loa nā hopena ʻaoʻao. Ma kahi e hoʻohālike, hiki iā ʻoe ke hoʻāʻo i ka esomeprazole, a i ʻole e hoʻohuli i nā mea blockers H 2, akā hānai lākou i ka ʻike ʻana i ka waikila hydrochloric e nawaliwali loa.

Aloha Ua heluhelu wau i ka loiloi a Jeanne a he hauʻoli nui :) i ka pūnāwai ua pau nā gastritis i hoʻopau ʻia, ua kuhikuhi ʻia lākou e mare. Hoʻopili me kahi nexium dropper. I ka wā mua ua manaʻo kekahi manaʻo o ke anuanu a haʻalulu, a laila manaʻo kekahi e ke hele mai ana ke one mai ka ʻōpū, ma ka lā 2 o koʻu ʻūhā a me ka mahana o ka mahana o 37, a laila he mau lā ma ia hope iho e kū nei, ʻā nā ʻeha ma koʻu kuʻi. ʻIke wau i kēia ma kaʻu mau leka - noi lākou iaʻu e halihali i kēia diary.

ʻAno, nalo nā hopena ʻokoʻa, ua hoʻopau ʻia ka lāʻau lapaʻau, akā ua nānā ʻia ka ʻai i ke kauwela a pau, no ka mea i lilo ka hapa liʻiliʻi i hōʻāwili i ke ʻano o ke kahe o ka poʻohiwi hema. I kahi pule i hala iho nei, ua hoʻomaka hou e puhi pinepine i ke scapula, e kūʻē i ke ʻano o ka hoʻokō ʻana i ka 1 pō (ʻoi aku ka hoʻonāukiuki i ka hāmeʻa ma kahi ʻōpū ʻole). A laila ua maʻi koʻikoʻi ka ʻaoʻao ʻākau a hoʻomaka nā nāwaliwali. Ua hoʻāʻo wau e kōkua iā Seth me Iberogast, ka Pake, akā pono wau e pono i nā lāʻau lapaʻau. Hoʻomaka wau e inu iā Nexium inehinei - i ke ahiahi, ʻo ka hōʻeha ʻana o ke kino a me ka nāwaliwali. I kēia lā ʻaʻohe ikaika o ka lā āpau, nā nāwaliwali weliweli, hiki ʻole iaʻu ke hele wāwae. Eia hou ka ʻeha o ka ʻāʻī a ua kū hoʻi ka mahana 37-37.5. I ka wā mua ua manaʻo wau he maʻi wau, akā ʻaʻohe mau hōʻailona ʻē aʻe o ka maʻi a me ka rinsing ʻaʻole kōkua. I ka pūnāwai ua manaʻo ʻia ʻaʻole he nui nā hopena ʻē aʻe, ma ka liʻiliʻi aʻaʻohe mea iʻike ʻole ʻia. Hiki ke loli ke ʻano o ka lāʻau lapaʻau? He aha kāu e ʻōlelo ai no ka famotidine? E pili ana i kona hopena?

ʻO Pariet (rabeprazole), nolpase (pantoprazole), nexium (esomeprazole) i ka hui o nā proton pump blockers a hiki ke hana i nā hopena like: maʻi a me nā maʻi like-flu. ʻO ka H2-blockers (famotidine, ranitidine, roxatidine, nizatidine) e hoʻemi ʻia i ka wela, no laila e hoʻāʻo ʻoe iā lākou. Loaʻa iā lākou nā hopena ʻē aʻe, akā aia manawa kūpono ʻaʻole ʻoe e loaʻa iā ʻoe a i ʻole ma ke liʻiliʻi iki. E ʻike i nā hopena pilikino ʻokoʻa o ka lāʻau lapaʻau ma ka pūnaewele. rlsnet.ru E ho'āʻo mua i kēlā mau blockers H2 e kūpono iā ʻoe no ke kumukūʻai. Ma keʻano holoʻokoʻa, nāwaliwali o ka H2 blockers ma mua o nā proton pump blockers. ʻAʻole wale e hoʻohana i ka cimetidine, he mea hoʻohana lapaʻau me ka nui o nā hopena maikaʻiʻole.

He aha ka mea e pono ai ka analogue palekana o rabeprozole (nā pua, noflux, ka manawa, zulbeks, hairabesol)?

I ke kumuhana, pono nā hoʻohālikelike āpau. ʻO ka lāʻau lapaʻau inoa inoa inoa (kuhikuhi, ka mea mua e komo i ka mākeke) ʻo Pariet. Ua manaʻo nui ʻia, ʻo nā lāʻau lapaʻau maikaʻi loa ka poʻe ʻenemi o ʻEulopa, ʻAmelika a me ka ʻIseraʻela. Akā e hoʻomanaʻo pono e kūʻai iki ʻia nā fakes i Rusia. No laila, hiki iā ʻoe ke hoʻohana i kekahi analogue (generic) inā kōkua ia iā ʻoe a ʻaʻole i hoʻokomo i nā hopena ʻaoʻao.

Ua maʻi au mai ka makahiki 1994. Loaʻa wau i ka herarr catarrhal o ka wehe ʻana o ka esophageal o ka diaphragm, catarrhal reflux esophagitis, ka hopena o ka antrum, gastroduodenitis superficial. I ka wā ma mua, aia kahi ʻōpū a me ka ʻili i loaʻa i ka duodenum. Hana maʻamau ʻo ia i kahi o kahi e noho ai. Hoʻokomo mau ʻia (kokoke i kēlā me kēia lā) ua lawe au iā Omeprazole, i kōkua iki a i kekahi manawa pōkole (i kekahi manawa pono wau e hana i kekahi mau papa i ka manawa e hoʻomaha ai i ka puʻuwai koʻikoʻi). ʻAʻole paʻa ka Heartburn. I ka manawa like, loaʻa iaʻu kahi rhinitis vasomotor. ʻAʻohe mea hanu. No ka lawe ʻana wau i nā puna waial. Kokoke ʻaʻole kōkua. No nā makahiki 4-5 i hala iho nei, ua hoʻōla nui mai ʻo ia (mai ka nui 46 a 56-58). Mai ka lauoho ʻē aʻe e waiho iki kekahi. I nā makahiki he ʻelua i hala iho nei, ua hoʻomaka ʻo ia e hakaka. I ka hana kekahi o kēlā a me kēia mea i hoʻopiʻi ʻia i loko ona. No kekahi kumu, ua kau ʻia ka lāʻau lapaʻau i kekahi mea me ka penicillin e pili ana i ka maʻi o ka penicillin, kahi mau mea e hoʻonā i ka hopena aluhi i nā maʻi e like me ka Quema o Quincke (ua hōʻike wau) No ka wā lōʻihi ua hoʻomaʻamaʻa wau i nā maʻi pā me nā peni a me nā ʻekehe me nā lālaki hormonal (i loko o kahi hale hoʻomaha). ʻO ka makahiki i hala ua hoʻomaka i kahi hou aʻe a nui aʻe. Ua ihoʻo Hemoglobin i 88, ka protein i ka 72-73. Ua mālama ʻia au e ka hematologist: māmā anemia, ʻōpū anemia. (No ka lawe ʻana i ka sorbifer. Maltofer ka hematologist i hoʻopaʻa ʻia i ka lāʻau, ʻaʻole ʻo ia e mālama). Ua koho ʻia nei e ka gastroenterologist iā Pariet. Ua kānalua maoli nei au i ka pono e lawe i kēlā lāʻau lapaʻau nui. Akā ke heluhelu nei wau i ka ʻikepili ma kāu pūnaewele e pili ana i ka hopena o nā lāʻau a me nā hoʻopiʻi ʻana mai ia lākou, ʻike wau he mea hiki wale nō iā ia ke kōkua iaʻu. A me nā hoʻopiʻi āpau ma ke ʻano o ka ʻōpū pōkole o ka hanu, bronchospasm, loaʻa ka momona, ka hoʻolilo ʻana o ka lauoho, ua ʻike nā leo. ʻAʻole wau i noʻonoʻo i ka hiki iā Omeprazole ke hana ʻino hou aʻe i ka maikaʻi, a wale wale no i ka olakino koʻu kino, i ka mea i manaʻoʻiʻo au ia no ka mea, he mea nui loa ka mea ʻulaʻawa.

E hoʻokō anei wau i ka hanu maʻamau i kēia manawa, e hoʻihoʻi ʻia koʻu hihiu, e hoʻi hou koʻu koʻikoʻi i kahi maʻamau, ...? (ʻAʻole maikaʻiʻole nā hōʻike maʻi alerekia, ʻaʻole hiki iaʻu ke loaʻa ke kuhikuhi i ka pulmonologist). Hiki i kekahi ke ʻoihana ke pane mai iaʻu, e aʻo mai i nā mea pehea e kū ai me kēia?

ʻO Rabeprazole a me omeprazole mai ka hui like ʻole, no laila like nā hopena ʻaoʻao. Mai manaʻo i kahi holomua palaka.

ʻO ka Asthma a me ka vasomotor rhinitis e pili ana i ka liklu acid mai ka esophagus a hiki i ka bronchi. Hoʻopau maʻamau kēia.

No ke aha ʻaʻole kōkua maikaʻi ʻo omeprazole i kahi maopopo ʻole. No ka hōʻoia, pono ke hana ʻia o kahi pā pH i kēlā me kēia lā.

Eia nō naʻe, makemake wau e hana nā hana omeprazole, a ʻo ke kumu maoli o kou pilikia i ka hernia hiatal. ʻO ke koho wale e kāpae ʻia (a laila hoʻomaka paha ke ola e hoʻomaikaʻi ʻia) ʻo ka hōʻino. ʻAʻole i haʻalele ʻia kou kūlana, no laila e pono ʻia ka hoʻomākaukau ʻana ma mua o ka hoʻomaʻemaʻe ʻana (e hoʻonui i ka hemoglobin, etc.). Akā, pono ʻoe e lawelawe ʻia ma muli, no ka mea ʻoi aku ka maikaʻi o ka maikaʻi.

O.N. Minushkin, L.V. Maslovsky, Yu.N. Loshchinina, N.Yu. Anikina,
ʻO ke Keʻena Hoʻonaʻauao a me nā ʻElimepekema Center o ke Aupuni Pelekikena o ka Russian Federation

I nā ʻāina hoʻomohala, i kēia mau makahiki i hala iho nei, ua piʻo ka nui o ka ulu ʻana o ka maʻi reflux gastroesophageal (GERD). Hoʻomaʻamaʻa ʻia nā hōʻailona GERD i kēlā me kēia lā e 10% o ka heluna o ka heluna, i ka hebedoma e 30%, a me ka mahina e 50%. ʻO ke ʻano i ka piʻi ʻana o ka ulu ʻana o GERD ke kumu e hoʻolaha ai ma ka 6th European Gastroenterological Week i ka slogan "XX kenekulia - ka makahiki o ka maʻi ulia pōpilikia, XXI - nā makahiki o GERD".

Ua hōʻike ʻia nā haʻawina Lūkini ma kahi o ka papahana WHO MONICA ma Novosibirsk i hōʻike i kahi hoʻohālikelike o ka GERD hoʻohālikelike i nā ikepili ma luna. Hoʻomaopopo ka Heartburn e 61.7% o nā kāne a me 63.6% o nā wahine, me 10,3% a me 15,1% pinepine a i ʻole (5). Hōʻike nā hualoaʻa i kā mākou noiʻi iho, pili i ka loiloi retrospective o nā ʻike mua o ka endoscopy o 5107 o nā maʻi gastroenterological ma kahi 5 mau makahiki, hōʻike ʻia nā hōʻailona endoskopiko o ka esophagitis reflux i ʻike ʻia i nā mea maʻi 1419 (27.8%), nona 880 mau kāne (28.8%) a he 539 mau wahine (26,3%) (hāʻawi ʻia ke kumukūʻai o ka huina o nā kāne a me nā wahine). Ua ʻike ʻia ka Catarrhal esophagitis i nā maʻi 890 (17.4%) - 538 kāne (17.8%) a me 352 wahine (17.2%). Erophive esophagitis - i 529 i hoʻopaʻa ʻia (10.4%) - 342 kāne (11.2%) a me 187 wahine (9.1%).

ʻO ka kūpono kūpono o ka GERD pono, no ka mea e pili ana kēia maʻi i ke ola o nā mea maʻi, a me ka lōʻihi o ka noho ʻana a me ka holomua o ka esophagitis hiki ke alakaʻi i ka ulu ʻana o ka hana, ʻo ka esophagus a Barrett a me ke kanesa o ka esophageal.

Hoʻomaʻamaʻa ka mālama ʻana i ka GERD i ka hoʻololi ʻana i ke ʻano o ka mea maʻi a me ka lāʻau lapaʻau lāʻau (2). I ka poʻe maʻi me ka esophagitis, ʻo ka pahuhopu o ka mālamaʻana e hoʻopau i nā hōʻailona e pili ana i ka acid reflux (heartburn, i kekahi manawa ka ʻeha ma hope o ka sternum) a hoʻomaikaʻi i ke ʻano o ke ola. I ka piha o ka esophagitis, lawe ʻia ka mālama ʻia e pale i ka hoʻomohala ʻana o nā hoʻopiʻi e like me ka esophageal tighture a me ka epithelial metaplasia (Barrett's esophagus).

I nā ʻano ʻo GERD āpau, loaʻa ka mālama mua ʻana i kahi pā ana no ka lāʻau lapaʻau ʻole (hoʻāla i ke poʻo o ka moena, ka hoʻolilo ʻana, ke kāʻai ʻana, ka papa ʻaina, a me kekahi mea) a me ka lawe ʻana i nā antacids. Inā hoʻomau nā hōʻailona ma kēia ʻano, ua hoʻopili ʻia ka lāʻau lapaʻau no 2-4 mau pule. ʻO nā koho koho mua ponoʻī huakaʻi maikaʻi loa ʻo ia nā pale pale proton. I kēia manawa ʻike nā ʻikepili i ka like o ka like me nā hopena like ʻole o nā ʻelele like o kēia hui o nā lāʻau lapaʻau (omeprazole, lanzoprazole, pantoprazole, rabeprazole a me esomeprazole) (9, 11). Ua hōʻike ʻia kekahi mau haʻawina o ka nui o ka esomeprazole ma luna o ka omeprazole ma ka pae o ka hoʻomakeʻa ʻana i ka ʻōpū o ka ʻōpū a me ka piʻi ʻana o ka hopena (10). Eia naʻe, nā ʻokoʻa i loaʻa i ke ʻano ma muli o nā ʻano like ʻole o ka lāʻau (40 mg a me 20 mg, kahi pākuʻi).

Loaʻa iā ʻoe iho i ka papa o ka mālama ʻana i nā mea maʻi o nā maʻi 115 (77 kāne, 38 mau wahine, ka makahiki 45.1 ± 1.2 mau makahiki) ʻo GERD 0-4 mau ʻihi omeprazole, esomeprazole, rabeprazole ma nā papa hana no nā hebedoma he 4 i hōʻike i ke kiʻekiʻe o ka maʻi lapaʻau a me ka endoscopic o nā haʻawina a pau. hoʻomākaukau (6, 7, 8).

Hāʻawi ʻia nā hana hoʻohālike o ke kiʻi lāʻau a me ka endoscopic i nā papa 1 a me 2.

ʻO ka nui o nā mea maʻi me ka hoʻōla piha o ka hoʻopau ʻana ma hope o 4 hebedoma o ka mālama ʻana me nā PPI like ʻole, e pili ana i ka pae o ka reflux zsophagitis

ʻO ka pākēpē o nā mea maʻi me ka hoʻomaha piha o ka puʻuwai ma hope o nā hebedoma 4 o ka mālama ʻana me nā PPI like ʻole

Hōʻike ʻia nā hōʻike i ka hana ʻoi aku ka maikaʻi o nā lāʻau āpau i hoʻohana ʻia i ka mālama ʻana i ka esophagitis erosive, ʻaʻohe ʻano nui o ka nui o nā mea maʻi me ka hoʻōla piha ʻana o ka ʻaʻai ma hope o nā hebedoma 4 o ka mālama ʻana me ka Omez, Pariet a me Nexium. Ua nānā ʻia kahi ʻano like like me ka nānā ʻana i ke kōkua ʻana o ke mau maʻi, ma ka puʻuwai naʻau. Hōʻike ka papa 2 ma kahi pono iā Omez.

No ka loiloi ʻana i ka pono o nā ʻano ʻano like ʻole o ka mālama mālama ʻana, ua hoʻohana ʻia ʻo Omez. ʻO kekahi o nā kumu i koho ʻia ai, ʻo ia kekahi o ka nui o ka pale i nā mea paʻa i loko o ka mākia o Russia a ʻaʻole hoʻi he mea haʻahaʻa i kona hopena i nā mākeke pale proton e hele aku i ka mākeke lāʻau Lūkini.

Ua loiloi mākou i ka maikaʻi o 4 o nā hana mālama mālama me ka Omez (omeprazole) ma kahi o 20 mg no 12 mau malama i nā maʻi me GERD 0 a me 1 tbsp. i ka hoʻokō 'ana i ke kala ʻana a me ka endoscopic me ka papa mālama aʻoaʻo.
1) lawe i ka Omez i kahi make o 20 mg / lā i kēlā me kēia lā (1 hui - 20 mau mea maʻi),
2) lawe i ka Omez ma kahi mahele o 20 mg / lā i kēlā me kēia lā (hui 2 - 20 mau kānaka),
3) ka lawe ʻana i ka Omez i kahi maʻa o 20 mg i ka mode "ma ka noi": 20 mg / lā me ka heartburn (hui 3 - 20 nā mea maʻi),
4) e lawe i ka Omez i kahi maʻa o 20 mg i ka hana "hopena pule": 20 mg / lā ma ka Pōʻalima, Pōʻalima a me ka Lāpule (hui 4 - 15 nā mea maʻi),
5) hui pūnaehana - nā mea maʻi i loaʻa ʻole i ka mālama mālama lāʻau (pūʻulu 5 - 30 nā mea maʻi).

Ua loaʻa ka nui o nā maʻi he 105 i ka hoʻopaʻa ʻana: 62 kāne (59%) a me nā wāhine 43 (41%). Loaʻa ka poʻe maʻi āpau i ka lāhui Europa. Hōʻike ʻia nā hiʻohiʻona o ka hui ma ka papa 3.

Ka hiʻohiʻona o nā mea maʻi i aʻo ʻia

Ma mua o ke komo ʻana i ka noiʻi, ua ʻike ʻia nā mea maʻi a pau i ka endoscopy (Papa 4), ka loiloi o ka hōʻailona a me ka maikaʻi o ke ola. Ua mālama ʻia ka mākaʻi Endoscopical Clinical i kēlā me kēia 3 mahina. ʻO ka loiloiʻana o ka hōʻailona o GERD ma endoscopy i hana ʻia e like me ka helu ʻana o Savary-Miller i ka hoʻololi ʻana o Carisson et al. Mālama nā mea maʻi i kahi diary i kēlā me kēia lā kahi a lākou i loiloi ai i ka piʻi ʻana o nā hōʻailona ma ka skala Likert, a ua hoʻohana ʻia kahi ʻōhua hoʻonaninani (VAS) e nānā i ke ʻano o ke ola. Ua loaʻa i nā mea maʻi ka hoʻomau ʻana o ka maʻi PPI i kahi papa holoʻokoʻa a hiki i ka hōʻea ʻana o nā hoʻomaʻamaʻa endoskopika hope, ma hope o ko lākou kuhikuhi ʻia ʻana i ka mālama mālama ʻana me ka Omez i kekahi o nā regimens.

ʻO ka kohoʻana o nā mea maʻi i nā pūʻulu pili i ke kiʻekiʻe o GERD

ʻO ka hui	Palapala GERD ma endoscopy
ʻO ka hui	ʻO GERD 0 mauʻike	ʻOi ʻO GERD 1 kō
Kāpae 1 (n = 20)	9 (45%)	11 (55%)
Kāpae 2 (n = 20)	8 (40%)	12 (60%)
Kākau 3 (n = 20)	11 (55%)	9 (45%)
A hui 4 (n = 15)	7 (46,6%)	8 (53,3%)
Kāpana 5 (n = 30)	13 (43,3%)	17 (56,6%)

Kahi ka māhele o nā pūʻulu. Hoʻohālikelike nā mea maʻi i kēlā me kēia hui i ka makahiki, ka lōʻihi o ka maʻi, ka index mass body (BMI), a me kekahi mau hōʻailona ʻē aʻe (papaʻaina 5).

Ka hōʻike ʻana o nā mea maʻi o nā hui ʻikepili

ʻO ka loiloi o ka kūpono o ka mālama mālama ʻia e like me ka endoscopy i hōʻike i kēia. I nā maʻi o nā hui 1 a me 2, ʻaʻole i ʻike ʻia ka ulu ʻana o ka erophive esophagitis. I nā mea maʻi o ka hui 3 me ka 1 kiʻekiʻe o GERD, ua ʻike ʻia kahi hoʻomaha o ka maʻi ma hope o 3 a me 6 mau malama ma 44,4% o nā hihia. I ka hui i nā mea maʻi 4, ʻike hou ʻia ka puka erosive me ka endoscopy i ʻike ʻia ma nā mea maʻi 7, kahi nui o 87.5%. I ka hoʻomanawanui o ka pūʻulu hoʻomalu, ʻike ʻia ka lohi i 100% o nā hihia 6 mau mahina ma hope o ka hopena o ka papa papa.

ʻO ka loiloi o ka hopena kūpono o ka mālama mālama pono e like me ka ʻike olakino

ʻO ka dinamika o ka pinepine o ka puʻuwai i ka wā o ka mālama mālama ʻana i nā hui like ʻole i hōʻike ʻia ma nā Figures 1-4.

Kiʻikuhi 1 Nā hōʻailona o ka hōʻailona ma ka poʻe maʻi o ka hui 1st (Omez 20 mg i kēlā me kēia lā)

Kiʻi 2 ʻO ka dinamics o nā hōʻailona i ka poʻe maʻi o ka hui 2 (Omez 20 mg i kēlā me kēia lā)